NSUN7 (NOP2/Sun RNA methyltransferase family member 7) - Rat Genome Database

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Gene: NSUN7 (NOP2/Sun RNA methyltransferase family member 7) Chlorocebus sabaeus
Analyze
Symbol: NSUN7
Name: NOP2/Sun RNA methyltransferase family member 7
RGD ID: 18763016
Description: ENCODES a protein that exhibits methyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN flagellated sperm motility (ortholog); sperm mitochondrion organization (ortholog); ASSOCIATED WITH Hyperglycinemia, Lactic Acidosis, and Seizures (ortholog); male infertility (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: putative methyltransferase NSUN7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1279,536,614 - 9,589,622 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl279,537,740 - 9,589,573 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604755,870,775 - 55,924,943 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
NSUN7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1279,536,614 - 9,589,622 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl279,537,740 - 9,589,573 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604755,870,775 - 55,924,943 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NSUN7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38440,749,955 - 40,811,184 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl440,749,925 - 40,811,184 (+)EnsemblGRCh38hg38GRCh38
GRCh37440,751,972 - 40,813,201 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36440,446,699 - 40,506,759 (+)NCBINCBI36Build 36hg18NCBI36
Celera441,194,556 - 41,255,316 (+)NCBICelera
Cytogenetic Map4p14NCBI
HuRef440,073,760 - 40,133,961 (+)NCBIHuRef
CHM1_1440,751,551 - 40,811,726 (+)NCBICHM1_1
T2T-CHM13v2.0440,723,823 - 40,785,135 (+)NCBIT2T-CHM13v2.0
Nsun7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39566,417,181 - 66,457,544 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl566,417,240 - 66,455,369 (+)EnsemblGRCm39 Ensembl
GRCm38566,259,838 - 66,299,927 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl566,259,897 - 66,298,026 (+)EnsemblGRCm38mm10GRCm38
MGSCv37566,651,364 - 66,689,255 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36566,539,260 - 66,577,151 (+)NCBIMGSCv36mm8
Celera563,558,668 - 63,596,664 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map534.34NCBI
Nsun7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81442,233,062 - 42,289,013 (-)NCBIGRCr8
mRatBN7.21441,878,562 - 41,935,238 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1441,879,293 - 41,934,949 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1442,224,836 - 42,287,402 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01443,524,923 - 43,587,491 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,005,706 - 42,068,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01443,525,530 - 43,584,621 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1443,527,579 - 43,584,343 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01443,315,334 - 43,374,692 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41444,556,251 - 44,582,930 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11444,558,641 - 44,585,321 (-)NCBI
Celera1441,060,653 - 41,087,334 (-)NCBICelera
Cytogenetic Map14p11NCBI
Nsun7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554436,789,224 - 6,830,813 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554436,788,155 - 6,830,659 (-)NCBIChiLan1.0ChiLan1.0
NSUN7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2340,931,709 - 40,991,735 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1441,123,658 - 41,183,689 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0435,071,093 - 35,131,207 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1440,922,714 - 40,982,315 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl440,922,714 - 40,982,315 (+)Ensemblpanpan1.1panPan2
NSUN7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1371,832,051 - 71,891,020 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl371,833,198 - 71,891,453 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha374,382,001 - 74,440,288 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0372,592,087 - 72,651,343 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl372,592,234 - 72,651,343 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1371,868,055 - 71,922,508 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0372,024,017 - 72,078,449 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0372,408,100 - 72,462,582 (-)NCBIUU_Cfam_GSD_1.0
Nsun7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528538,136,705 - 38,171,312 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364828,126,720 - 8,162,183 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364828,126,812 - 8,161,899 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NSUN7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl831,810,320 - 31,925,472 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1831,810,012 - 31,920,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2833,428,452 - 33,536,833 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Nsun7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476126,268,868 - 26,310,652 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476126,267,988 - 26,310,048 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 16 16
Low 20 12 42
Below cutoff 5 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015158   ⟹   ENSCSAP00000013105
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl279,537,740 - 9,589,573 (-)Ensembl
RefSeq Acc Id: XM_038008604   ⟹   XP_037864532
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604755,870,775 - 55,924,943 (-)NCBI
RefSeq Acc Id: XM_038008605   ⟹   XP_037864533
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604755,872,278 - 55,924,943 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037864532 (Get FASTA)   NCBI Sequence Viewer  
  XP_037864533 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013105.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000013105   ⟸   ENSCSAT00000015158
RefSeq Acc Id: XP_037864532   ⟸   XM_038008604
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RWW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037864533   ⟸   XM_038008605
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017072 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015158.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro MeTrfase_RsmB-F_NOP2_cat UniProtKB/TrEMBL
  MeTrfase_RsmB/NOP2 UniProtKB/TrEMBL
  NSUN5_7_fdxn-like UniProtKB/TrEMBL
  NSUN7 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene NSUN7 ENTREZGENE
PANTHER METHYLTRANSFERASE NSUN7-RELATED UniProtKB/TrEMBL
  PTHR14663 UniProtKB/TrEMBL
Pfam Methyltr_RsmB-F UniProtKB/TrEMBL
  NSUN5_fdxn-like UniProtKB/TrEMBL
PROSITE SAM_MT_RSMB_NOP UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0D9RWW6 ENTREZGENE, UniProtKB/TrEMBL