ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6) - Rat Genome Database

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Gene: ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6) Chlorocebus sabaeus
Analyze
Symbol: ENTPD6
Name: ectonucleoside triphosphate diphosphohydrolase 6
RGD ID: 18760215
Description: ENCODES a protein that exhibits guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity (ortholog); nucleoside diphosphate phosphatase activity (ortholog); ribonucleoside triphosphate phosphatase activity (ortholog); INVOLVED IN response to calcium ion (ortholog); response to magnesium ion (ortholog); ASSOCIATED WITH obesity (ortholog); seminoma (ortholog); FOUND IN cell surface (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ectonucleoside triphosphate diphosphohydrolase 6 (putative)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660787,827,280 - 7,857,456 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Disease Annotations     Click to see Annotation Detail View
obesity  (ISO)
seminoma  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ENTPD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660787,827,280 - 7,857,456 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ENTPD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382025,195,712 - 25,228,075 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2025,195,693 - 25,228,075 (+)EnsemblGRCh38hg38GRCh38
GRCh372025,176,348 - 25,208,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362025,124,372 - 25,155,360 (+)NCBINCBI36Build 36hg18NCBI36
Build 342025,124,371 - 25,155,360NCBI
Celera2025,250,075 - 25,281,095 (+)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2025,133,642 - 25,164,663 (+)NCBIHuRef
CHM1_12025,177,223 - 25,208,244 (+)NCBICHM1_1
T2T-CHM13v2.02025,260,296 - 25,293,060 (+)NCBIT2T-CHM13v2.0
Entpd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392150,590,959 - 150,613,595 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2150,590,962 - 150,613,595 (+)EnsemblGRCm39 Ensembl
GRCm382150,748,980 - 150,771,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2150,749,042 - 150,771,675 (+)EnsemblGRCm38mm10GRCm38
MGSCv372150,574,817 - 150,597,410 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362150,440,590 - 150,463,114 (+)NCBIMGSCv36mm8
Celera2151,982,124 - 152,004,717 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.74NCBI
Entpd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83160,036,055 - 160,058,580 (+)NCBIGRCr8
mRatBN7.23139,575,659 - 139,598,163 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3139,575,686 - 139,598,154 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,471,519 - 143,494,099 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03152,055,255 - 152,077,835 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03149,804,015 - 149,826,553 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03146,546,424 - 146,568,828 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,546,387 - 146,568,825 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03152,905,464 - 152,927,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,385,480 - 141,407,860 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,291,052 - 141,313,433 (+)NCBI
Celera3138,337,640 - 138,359,993 (+)NCBICelera
Cytogenetic Map3q41NCBI
Entpd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541531,219,909 - 31,245,107 (+)NCBIChiLan1.0ChiLan1.0
ENTPD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22126,069,393 - 26,105,731 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12026,066,122 - 26,101,884 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02025,138,856 - 25,169,765 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12025,544,808 - 25,576,712 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2025,544,880 - 25,576,707 (+)Ensemblpanpan1.1panPan2
ENTPD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1231,374,793 - 1,422,625 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl231,374,199 - 1,420,802 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,404,549 - 1,450,380 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0231,615,237 - 1,661,162 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl231,615,277 - 1,661,177 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1231,456,204 - 1,501,946 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0231,580,817 - 1,626,596 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0231,548,077 - 1,593,906 (+)NCBIUU_Cfam_GSD_1.0
Entpd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640147,178,218 - 147,207,324 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936620598,592 - 627,822 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936620598,677 - 627,766 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENTPD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,908,252 - 30,934,083 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,908,747 - 30,930,774 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Entpd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624939313,768 - 333,694 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624939313,763 - 333,640 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008019102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_008019102   ⟹   XP_008017293
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660787,827,280 - 7,857,456 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008017293 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013540.1
RefSeq Acc Id: XP_008017293   ⟸   XM_008019102
- UniProtKB: A0A0D9RY51 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017511 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015606.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.40 UniProtKB/TrEMBL
  Exopolyphosphatase. Domain 2 UniProtKB/TrEMBL
InterPro GDA1_CD39_NTPase UniProtKB/TrEMBL
KEGG Report csab:103247059 UniProtKB/TrEMBL
NCBI Gene ENTPD6 ENTREZGENE
PANTHER ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6 UniProtKB/TrEMBL
  PTHR11782 UniProtKB/TrEMBL
Pfam GDA1_CD39 UniProtKB/TrEMBL
PROSITE GDA1_CD39_NTPASE UniProtKB/TrEMBL
UniProt A0A0D9RY51 ENTREZGENE, UniProtKB/TrEMBL