MDGA1 (MAM domain containing glycosylphosphatidylinositol anchor 1) - Rat Genome Database

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Gene: MDGA1 (MAM domain containing glycosylphosphatidylinositol anchor 1) Chlorocebus sabaeus
Analyze
Symbol: MDGA1
Name: MAM domain containing glycosylphosphatidylinositol anchor 1
RGD ID: 18752921
Description: INVOLVED IN brain development (ortholog); cerebral cortex radially oriented cell migration (ortholog); inhibitory synapse assembly (ortholog); ASSOCIATED WITH acute megakaryocytic leukemia (ortholog); FOUND IN axon (ortholog); cell surface (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MAM domain-containing glycosylphosphatidylinositol anchor protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11734,443,453 - 34,506,531 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1734,474,974 - 34,501,685 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604437,589,643 - 37,652,643 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MDGA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11734,443,453 - 34,506,531 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1734,474,974 - 34,501,685 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604437,589,643 - 37,652,643 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MDGA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38637,630,679 - 37,697,883 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl637,630,679 - 37,699,306 (-)EnsemblGRCh38hg38GRCh38
GRCh37637,598,455 - 37,665,659 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36637,708,262 - 37,773,744 (-)NCBINCBI36Build 36hg18NCBI36
Build 34637,708,261 - 37,773,744NCBI
Celera639,155,326 - 39,220,811 (-)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef637,319,586 - 37,385,201 (-)NCBIHuRef
CHM1_1637,602,083 - 37,667,562 (-)NCBICHM1_1
T2T-CHM13v2.0637,455,697 - 37,522,898 (-)NCBIT2T-CHM13v2.0
Mdga1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391730,046,930 - 30,107,557 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1730,046,923 - 30,189,061 (-)EnsemblGRCm39 Ensembl
GRCm381729,827,956 - 29,888,583 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,827,949 - 29,970,087 (-)EnsemblGRCm38mm10GRCm38
MGSCv371729,964,903 - 30,024,827 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361729,554,970 - 29,614,894 (-)NCBIMGSCv36mm8
Celera1730,363,040 - 30,422,558 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.54NCBI
Mdga1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8207,901,856 - 7,965,834 (-)NCBIGRCr8
mRatBN7.2207,900,327 - 7,964,309 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,904,358 - 7,963,471 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx208,600,465 - 8,659,560 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0207,961,630 - 8,020,725 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0208,434,933 - 8,493,730 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0208,515,142 - 8,574,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl208,515,142 - 8,574,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02010,707,850 - 10,766,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4208,149,686 - 8,200,149 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1208,150,174 - 8,245,666 (-)NCBI
Celera209,435,545 - 9,495,254 (-)NCBICelera
Cytogenetic Map20p12NCBI
Mdga1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554375,547,666 - 5,601,156 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554375,547,684 - 5,596,980 (+)NCBIChiLan1.0ChiLan1.0
MDGA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2552,104,165 - 52,171,655 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1647,975,920 - 48,041,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0637,197,192 - 37,264,426 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1638,387,640 - 38,453,796 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl638,394,341 - 38,453,604 (-)Ensemblpanpan1.1panPan2
MDGA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1126,655,586 - 6,716,619 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl126,659,910 - 6,686,760 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,672,502 - 6,735,801 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0127,119,350 - 7,183,292 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl127,119,349 - 7,182,289 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1126,655,803 - 6,719,163 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0126,738,942 - 6,801,936 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0126,836,805 - 6,901,038 (-)NCBIUU_Cfam_GSD_1.0
Mdga1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494642,112,653 - 42,169,418 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647621,790,051 - 21,847,558 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647621,790,058 - 21,843,744 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MDGA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl733,210,158 - 33,269,130 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1733,205,736 - 33,269,213 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2738,109,505 - 38,173,065 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mdga1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475420,434,648 - 20,481,206 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475420,434,625 - 20,485,402 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 1 6
Low 35 12 54
Below cutoff 7

Sequence


RefSeq Acc Id: ENSCSAT00000008593   ⟹   ENSCSAP00000006735
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1734,474,974 - 34,501,685 (+)Ensembl
RefSeq Acc Id: XM_007972739   ⟹   XP_007970930
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11734,443,453 - 34,501,247 (+)NCBI
Vero_WHO_p1.0NW_02366604437,594,579 - 37,652,643 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007972740   ⟹   XP_007970931
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11734,443,453 - 34,506,531 (+)NCBI
Vero_WHO_p1.0NW_02366604437,589,643 - 37,652,643 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007972741   ⟹   XP_007970932
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11734,443,453 - 34,506,531 (+)NCBI
Vero_WHO_p1.0NW_02366604437,589,643 - 37,652,643 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007970930 (Get FASTA)   NCBI Sequence Viewer  
  XP_007970931 (Get FASTA)   NCBI Sequence Viewer  
  XP_007970932 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006735
  ENSCSAP00000006735.1
RefSeq Acc Id: XP_007970931   ⟸   XM_007972740
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RDP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007970932   ⟸   XM_007972741
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RDP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007970930   ⟸   XM_007972739
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RDP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000006735   ⟸   ENSCSAT00000008593


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008593.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
NCBI Gene MDGA1 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1 UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A0D9RDP6 ENTREZGENE, UniProtKB/TrEMBL