CNTROB (centrobin, centriole duplication and spindle assembly protein) - Rat Genome Database

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Gene: CNTROB (centrobin, centriole duplication and spindle assembly protein) Chlorocebus sabaeus
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Symbol: CNTROB
Name: centrobin, centriole duplication and spindle assembly protein
RGD ID: 18740750
Description: ENCODES a protein that exhibits protein domain specific binding (inferred); INVOLVED IN centriole replication (inferred); centrosome separation (inferred); mitotic cytokinetic process (inferred); ASSOCIATED WITH common variable immunodeficiency (ortholog); cone-rod dystrophy 6 (ortholog); Diamond-Blackfan anemia (ortholog); FOUND IN centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: centrobin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,320,557 - 7,337,746 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,320,586 - 7,338,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,070,347 - 14,087,586 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriole  (IEA)
centrosome  (IEA,ISO)
ciliary basal body  (IEA)
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CNTROB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,320,557 - 7,337,746 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,320,586 - 7,338,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,070,347 - 14,087,586 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CNTROB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,932,081 - 7,949,920 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,932,101 - 7,949,920 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,835,399 - 7,853,238 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,776,198 - 7,793,621 (+)NCBINCBI36Build 36hg18NCBI36
Celera177,863,187 - 7,880,713 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,730,040 - 7,747,892 (+)NCBIHuRef
CHM1_1177,844,229 - 7,862,013 (+)NCBICHM1_1
T2T-CHM13v2.0177,837,509 - 7,855,338 (+)NCBIT2T-CHM13v2.0
Cntrob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,188,735 - 69,214,720 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,190,313 - 69,214,601 (-)EnsemblGRCm39 Ensembl
GRCm381169,297,909 - 69,323,898 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,299,487 - 69,323,775 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,112,998 - 69,137,375 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,115,691 - 69,139,970 (-)NCBIMGSCv36mm8
Celera1176,253,419 - 76,277,856 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.51NCBI
Cntrob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,521,338 - 54,546,569 (-)NCBIGRCr8
mRatBN7.21054,022,523 - 54,047,793 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,022,852 - 54,044,849 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,684,543 - 58,706,468 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,173,159 - 58,195,082 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,681,256 - 53,703,227 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,901,929 - 55,927,121 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,901,901 - 55,924,158 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,644,004 - 55,666,957 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,094,489 - 56,116,421 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,108,146 - 56,129,842 (-)NCBI
Celera1053,179,449 - 53,201,359 (-)NCBICelera
Cytogenetic Map10q24NCBI
Cntrob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,993,952 - 9,009,928 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,993,528 - 9,010,829 (-)NCBIChiLan1.0ChiLan1.0
CNTROB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,530,146 - 15,546,805 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,496,297 - 17,512,824 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,967,297 - 7,983,743 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,953,617 - 7,970,148 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,953,660 - 7,970,148 (+)Ensemblpanpan1.1panPan2
CNTROB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,777,242 - 32,811,747 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,777,341 - 32,811,518 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,908,508 - 32,948,110 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,874,335 - 32,914,229 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,889,100 - 32,914,223 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,842,045 - 32,881,648 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,798,079 - 32,837,667 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,977,207 - 33,017,099 (+)NCBIUU_Cfam_GSD_1.0
Cntrob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,700,460 - 47,716,775 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,175,562 - 1,191,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,174,559 - 1,191,171 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNTROB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,181,642 - 53,201,667 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,181,096 - 53,201,670 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,532,441 - 55,602,642 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cntrob
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,514,609 - 10,532,563 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,514,593 - 10,532,661 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CNTROB
312 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000009158   ⟹   ENSCSAP00000007288
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl167,320,586 - 7,338,369 (+)Ensembl
RefSeq Acc Id: XM_008010233   ⟹   XP_008008424
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1167,320,557 - 7,337,746 (+)NCBI
Vero_WHO_p1.0NW_02366605914,070,347 - 14,087,586 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008010234   ⟹   XP_008008425
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1167,321,675 - 7,337,746 (+)NCBI
Vero_WHO_p1.0NW_02366605914,070,347 - 14,086,772 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008008424 (Get FASTA)   NCBI Sequence Viewer  
  XP_008008425 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007288
  ENSCSAP00000007288.1
RefSeq Acc Id: XP_008008424   ⟸   XM_008010233
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RF99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008008425   ⟸   XM_008010234
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000007288   ⟸   ENSCSAT00000009158


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011070 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009158.1 UniProtKB/TrEMBL
InterPro Centrobin UniProtKB/TrEMBL
KEGG Report csab:103242334 UniProtKB/TrEMBL
NCBI Gene CNTROB ENTREZGENE
PANTHER CENTROBIN UniProtKB/TrEMBL
  PTHR34439 UniProtKB/TrEMBL
UniProt A0A0D9RF99 ENTREZGENE, UniProtKB/TrEMBL