LRGUK (leucine rich repeats and guanylate kinase domain containing) - Rat Genome Database

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Gene: LRGUK (leucine rich repeats and guanylate kinase domain containing) Chlorocebus sabaeus
Analyze
Symbol: LRGUK
Name: leucine rich repeats and guanylate kinase domain containing
RGD ID: 18651349
Description: ENCODES a protein that exhibits guanylate kinase activity (inferred); INVOLVED IN axoneme assembly (ortholog); spermatogenesis (ortholog); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN acrosomal vesicle (ortholog); manchette (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat and guanylate kinase domain-containing protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121102,753,877 - 102,884,558 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21102,755,344 - 102,884,003 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666042463,822 - 606,248 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LRGUK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121102,753,877 - 102,884,558 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21102,755,344 - 102,884,003 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666042463,822 - 606,248 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LRGUK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387134,127,340 - 134,276,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7134,127,299 - 134,264,595 (+)EnsemblGRCh38hg38GRCh38
GRCh377133,812,093 - 133,949,347 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367133,462,645 - 133,599,473 (+)NCBINCBI36Build 36hg18NCBI36
Celera7128,549,620 - 128,686,380 (+)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7128,113,745 - 128,250,751 (+)NCBIHuRef
CHM1_17133,746,675 - 133,883,286 (+)NCBICHM1_1
T2T-CHM13v2.07135,424,298 - 135,584,803 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27133,156,684 - 133,293,312 (+)NCBI
Lrguk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39634,006,183 - 34,110,969 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl634,006,379 - 34,110,969 (+)EnsemblGRCm39 Ensembl
GRCm38634,029,245 - 34,134,034 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl634,029,448 - 34,134,034 (+)EnsemblGRCm38mm10GRCm38
MGSCv37633,979,448 - 34,084,034 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36633,959,606 - 34,064,192 (+)NCBIMGSCv36mm8
Celera634,025,402 - 34,131,289 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map614.75NCBI
Lrguk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8463,614,431 - 63,737,463 (+)NCBIGRCr8
mRatBN7.2462,647,222 - 62,770,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl462,647,264 - 62,770,319 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx467,598,875 - 67,705,095 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0463,514,587 - 63,620,819 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0461,917,002 - 62,023,226 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0461,419,987 - 61,544,748 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl461,420,009 - 61,544,446 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0461,143,324 - 61,265,284 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4461,348,199 - 61,458,380 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1461,624,343 - 61,733,924 (+)NCBI
Celera457,700,495 - 57,807,232 (+)NCBICelera
Cytogenetic Map4q22NCBI
Lrguk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541033,753,999 - 33,870,523 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541033,753,411 - 33,870,512 (-)NCBIChiLan1.0ChiLan1.0
LRGUK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26170,942,941 - 171,097,100 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1722,955,438 - 23,107,079 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07126,087,557 - 126,225,253 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17138,595,150 - 138,731,914 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7138,595,150 - 138,731,507 (+)Ensemblpanpan1.1panPan2
LRGUK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1143,191,324 - 3,301,306 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl143,193,813 - 3,301,293 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha142,846,409 - 2,957,446 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0142,919,311 - 3,030,563 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl142,923,556 - 3,030,548 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1143,123,357 - 3,234,896 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0142,867,985 - 2,979,285 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0143,014,095 - 3,125,199 (-)NCBIUU_Cfam_GSD_1.0
Lrguk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511821,359,788 - 21,462,808 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365791,492,389 - 1,595,465 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365791,492,868 - 1,595,402 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRGUK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1814,957,509 - 15,071,876 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11814,957,257 - 15,074,978 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21815,904,316 - 16,021,336 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Lrguk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247832,112,121 - 2,263,632 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
65 25 19 24 24 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000007454   ⟹   ENSCSAP00000005632
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl21102,755,344 - 102,884,003 (+)Ensembl
RefSeq Acc Id: XM_007982967   ⟹   XP_007981158
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.121102,753,878 - 102,838,757 (+)NCBI
Vero_WHO_p1.0NW_023666042502,145 - 606,248 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007982968   ⟹   XP_007981159
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.121102,753,877 - 102,838,757 (+)NCBI
Vero_WHO_p1.0NW_023666042502,145 - 606,248 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007982970   ⟹   XP_007981161
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.121102,753,881 - 102,884,147 (+)NCBI
Vero_WHO_p1.0NW_023666042463,822 - 606,220 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007981158 (Get FASTA)   NCBI Sequence Viewer  
  XP_007981159 (Get FASTA)   NCBI Sequence Viewer  
  XP_007981161 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005632.1
RefSeq Acc Id: XP_007981159   ⟸   XM_007982968
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007981158   ⟸   XM_007982967
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007981161   ⟸   XM_007982970
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RAJ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000005632   ⟸   ENSCSAT00000007454


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009415 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007454.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro GK/Ca_channel_bsu UniProtKB/TrEMBL
  Guanylate_kin-like_dom UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene LRGUK ENTREZGENE
PANTHER GUANYLATE KINASE-RELATED UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Guanylate_kin UniProtKB/TrEMBL
  LRR_4 UniProtKB/TrEMBL
  LRR_9 UniProtKB/TrEMBL
PROSITE GUANYLATE_KINASE_2 UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART GuKc UniProtKB/TrEMBL
  LRR_SD22 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9RAJ3 ENTREZGENE, UniProtKB/TrEMBL