MVB12A (multivesicular body subunit 12A)

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Gene: MVB12A (multivesicular body subunit 12A) Chlorocebus sabaeus

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Symbol:

MVB12A

Name:

multivesicular body subunit 12A

RGD ID:

18648907

Description:

ENCODES a protein that exhibits lipid binding (inferred); SH3 domain binding (inferred); ubiquitin binding (inferred); INVOLVED IN endosome to lysosome transport via multivesicular body sorting pathway (inferred); protein transport (inferred); receptor catabolic process (inferred); ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); cytosol (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,917,568 - 15,923,168 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	15,917,539 - 15,923,361 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	3,512,867 - 3,519,567 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

human immunodeficiency virus infectious disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endosome to lysosome transport via multivesicular body sorting pathway (IEA)

protein transport (IEA)

receptor catabolic process (IEA)

regulation of epidermal growth factor receptor signaling pathway (IEA)

viral budding (IEA)

virus maturation (IEA)

Cellular Component

centrosome (IEA)

cytoplasm (IEA)

cytosol (IEA)

endosome (IEA)

ESCRT I complex (IEA)

intracellular membrane-bounded organelle (IEA)

late endosome membrane (IEA)

membrane (IEA)

vesicle (IEA)

Molecular Function

lipid binding (IEA)

protein binding (ISO)

SH3 domain binding (IEA)

ubiquitin binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

MVB12A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,917,568 - 15,923,168 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	15,917,539 - 15,923,361 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	3,512,867 - 3,519,567 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

MVB12A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	17,405,741 - 17,425,332 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	17,405,722 - 17,433,724 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	17,516,550 - 17,536,141 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	17,391,912 - 17,397,140 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	17,432,663 - 17,437,892 (+)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	17,096,852 - 17,102,055 (+)	NCBI		HuRef
CHM1_1	19	17,530,417 - 17,535,642 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	17,540,476 - 17,560,094 (+)	NCBI		T2T-CHM13v2.0

Mvb12a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	71,995,552 - 72,000,670 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	71,995,566 - 72,000,729 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	71,542,907 - 71,548,026 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	71,542,922 - 71,548,085 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	74,066,829 - 74,071,925 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	74,471,919 - 74,477,015 (+)	NCBI		MGSCv36	mm8
Celera	8	74,053,836 - 74,058,731 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.43	NCBI

Mvb12a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	18,286,231 - 18,291,096 (+)	NCBI		GRCr8
mRatBN7.2	16	18,252,227 - 18,257,111 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	18,252,222 - 18,257,539 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	18,303,210 - 18,308,039 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	19,436,449 - 19,441,045 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	18,356,148 - 18,360,977 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	19,973,611 - 19,978,479 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	19,973,636 - 19,978,478 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	19,833,926 - 19,838,784 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	18,726,945 - 18,731,772 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	18,726,942 - 18,731,769 (+)	NCBI
Celera	16	18,457,206 - 18,462,083 (+)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Mvb12a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	839,328 - 840,664 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	839,328 - 842,160 (-)	NCBI	ChiLan1.0	ChiLan1.0

MVB12A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	22,289,570 - 22,294,844 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	21,296,143 - 21,301,414 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	16,906,449 - 16,911,717 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	17,880,073 - 17,885,546 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	17,880,073 - 17,894,044 (+)	Ensembl	panpan1.1		panPan2

MVB12A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	45,365,850 - 45,370,114 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	45,365,852 - 45,370,014 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	45,279,673 - 45,283,942 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	45,853,051 - 45,857,318 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	45,852,450 - 45,857,513 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	45,089,402 - 45,093,830 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	45,499,205 - 45,503,471 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	45,775,232 - 45,779,500 (-)	NCBI		UU_Cfam_GSD_1.0

Mvb12a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	203,929,003 - 203,932,598 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	3,477,690 - 3,481,968 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	3,478,142 - 3,481,968 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MVB12A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	60,271,026 - 60,275,971 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	60,271,020 - 60,275,972 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Mvb12a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624908	563,814 - 567,266 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624908	562,380 - 582,765 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007995722	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000003633 ⟹ ENSCSAP00000001909

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	6	15,917,539 - 15,923,361 (+)	Ensembl

RefSeq Acc Id:

XM_007995722 ⟹ XP_007993913

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	15,917,568 - 15,923,168 (+)	NCBI
Vero_WHO_p1.0	NW_023666074	3,512,867 - 3,519,567 (-)	NCBI

Sequence:

show sequence

CCCGCATGGCCTTCTGGTAGTTGTAGTTCGACCGCGAGCGCTGCCGTCGGGAGGCTGCTCCGAG
GTTCCAGGCTGTCCCCCACGACCCCGCCTTCGGCGCTCCGATCGCAGAATGGATCCTGTACCCG
GGACAGACTCGGCGCCGCTGGCTGGCCTGGCTTGGTCGTCGGCCTCTGCACCCCCGCCGCGGGG
GTTCAGCGCGATCTCCTGCACCGTCGAGGGGGCACCCGCCAGCTTTGGCAAGAGCTTCGCGCAG
AAATCTGGCTACTTCCTGTGCCTTAGTTCTCTGGGCAGCTTAGAGAACCCCCAGGAGAACGTGG
TGGCCGATATCCAGATCGTGGTGGACAAGAGCCCCCTGCCGCTGGGCTTCTCCCCGGTCTGCGA
CCCCATGGATTCCAAGGCCTCTGTGTCCAAGAAGAAACGCATGTGTGTGAAGCTGTTGCCCCTG
GGAGCTGCAGACACAGCTGTGTTTGATGTCCGGCTGAGTGGAAAGACCAAGACAGTGCCTGGAT
ACCTTCGAATAGGGGACATGGGCGGCTTTGCCATCTGGTGCAAGAAGGCCAAGGCGCCGAGGCC
AGTGCCCAAGCCCCGAGGTCTCAGCCGCGACATGCAGGGCCTGTCTCTGGATGCAGCCAGCCAG
CCGAGTAAGGGCAGCCTCCTGGAGCGGACTCCGTCAAGGCTGGGCTCTCGGGCATCCACTCTGC
GGAGGAATGACTCCATCTACGAGGCCTCTAGCCTCTATGGCATCTCAGCCATGGATGGGGTTCC
CTTCACACTCCACCCACGATTTGAGGGCAAGAGCTGCAGCCCCCTGGCCTTCTCTGCTTTTGGG
GACCTGACCATCAAGTCTCTGGCGGACATTGAGGAGGAGTATAACTACGGCTTCGTGGTGGAGA
AGACCGCGGCTGCCCGCCTGCCCCCCAGCGTCTCGTAGTCCCTCACCCGTCCGCGGGAAGAGCC
CCCTTACGCCACCCCCACCCCCGGCCAGCCTGGGGCCACCCCGCCTCACTGCATCCTGGGAACC
TCCGCCCTGCAAGGCTTTGCTATCTTCAGCCACTGGGCGGAGCTGCAGCTCTGGAGGAGGGGGC
GGGTCGAAGCTGCGTGGTGATGGGGTCTCCACCCCCAGGCCCTGCCGGGCAGGGCTGGAGCTGG
ACAGAAGCCAGTGCCTTTAAGTCATTCGTGTCAAAACCCTCTAGGGTCCGGAGGCAACGCGGGT
GTCCTCCTGGCAATAAACACTACCTGGTTCACGCCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007993913	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000001909.1

RefSeq Acc Id:	XP_007993913 ⟸ XM_007995722
- UniProtKB:	A0A0D9QZX0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000001909 ⟸ ENSCSAT00000003633

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000005599	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000003633.1	UniProtKB/TrEMBL
Gene3D-CATH	2.100.10.50	UniProtKB/TrEMBL
InterPro	MABP	UniProtKB/TrEMBL
	MVB12A	UniProtKB/TrEMBL
	MVB12A/B	UniProtKB/TrEMBL
	UMA	UniProtKB/TrEMBL
KEGG Report	csab:103234141	UniProtKB/TrEMBL
NCBI Gene	MVB12A	ENTREZGENE
PANTHER	MULTIVESICULAR BODY SUBUNIT 12A	UniProtKB/TrEMBL
	PTHR31612	UniProtKB/TrEMBL
Pfam	DUF2464	UniProtKB/TrEMBL
PROSITE	MABP	UniProtKB/TrEMBL
	UMA	UniProtKB/TrEMBL
UniProt	A0A0D9QZX0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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