PBX1 (PBX homeobox 1) - Rat Genome Database

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Gene: PBX1 (PBX homeobox 1) Chlorocebus sabaeus
Analyze
Symbol: PBX1
Name: PBX homeobox 1
RGD ID: 18647569
Description: ENCODES a protein that exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN adrenal gland development (ortholog); animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); brain infarction (ortholog); Burkitt lymphoma (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pre-B-cell leukemia transcription factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,990,553 - 64,317,901 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2563,989,612 - 64,084,673 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605565,810,334 - 66,103,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PBX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,990,553 - 64,317,901 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2563,989,612 - 64,084,673 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605565,810,334 - 66,103,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PBX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381164,559,184 - 164,886,047 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1164,555,584 - 164,899,296 (+)EnsemblGRCh38hg38GRCh38
GRCh371164,528,421 - 164,855,284 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,795,561 - 163,082,934 (+)NCBINCBI36Build 36hg18NCBI36
Build 341161,260,594 - 161,547,967NCBI
Celera1137,634,090 - 137,926,324 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1135,774,690 - 136,068,016 (+)NCBIHuRef
CHM1_11165,951,428 - 166,243,870 (+)NCBICHM1_1
T2T-CHM13v2.01163,905,317 - 164,232,389 (+)NCBIT2T-CHM13v2.0
Pbx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,946,933 - 168,259,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,946,933 - 168,259,839 (-)EnsemblGRCm39 Ensembl
GRCm381168,119,364 - 168,432,365 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,119,364 - 168,432,270 (-)EnsemblGRCm38mm10GRCm38
MGSCv371170,049,495 - 170,362,389 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,956,674 - 170,268,631 (-)NCBIMGSCv36mm8
MGSCv361169,328,392 - 169,641,347 (-)NCBIMGSCv36mm8
Celera1170,542,293 - 170,864,365 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map175.95NCBI
Pbx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81382,811,664 - 83,121,447 (-)NCBIGRCr8
mRatBN7.21380,278,766 - 80,588,563 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1380,278,770 - 80,588,594 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,940,830 - 83,217,210 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01384,248,904 - 84,525,004 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01381,480,869 - 81,756,919 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01386,390,741 - 86,671,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1386,390,741 - 86,451,002 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01391,028,026 - 91,307,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41383,839,256 - 84,115,516 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11383,853,894 - 84,129,704 (-)NCBI
Celera1380,014,082 - 80,284,838 (-)NCBICelera
Cytogenetic Map13q24NCBI
Pbx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546211,812,649 - 12,082,316 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546211,777,168 - 12,083,068 (-)NCBIChiLan1.0ChiLan1.0
PBX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,886,020 - 85,212,543 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1184,554,490 - 84,880,947 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01139,985,392 - 140,311,845 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11143,778,426 - 144,104,493 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1143,778,701 - 144,104,797 (+)Ensemblpanpan1.1panPan2
PBX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13818,378,997 - 18,703,694 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3818,418,093 - 18,703,497 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3818,435,288 - 18,759,350 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03818,460,019 - 18,784,434 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3818,458,914 - 18,783,979 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13818,431,748 - 18,755,044 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03818,781,894 - 19,105,974 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03819,078,211 - 19,402,654 (-)NCBIUU_Cfam_GSD_1.0
Pbx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344102,354,727 - 102,593,874 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648120,203,405 - 20,440,629 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648120,200,236 - 20,440,623 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PBX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl485,824,666 - 86,170,191 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1485,824,590 - 86,170,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2493,531,066 - 93,876,673 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pbx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248262,945,004 - 3,215,110 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248262,944,272 - 3,250,957 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 19 35 35 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000008767   ⟹   ENSCSAP00000006900
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2563,989,612 - 64,084,673 (-)Ensembl
RefSeq Acc Id: XM_007989707   ⟹   XP_007987898
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12564,024,342 - 64,317,898 (-)NCBI
Vero_WHO_p1.0NW_02366605565,810,334 - 66,103,813 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007989711   ⟹   XP_007987902
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12564,029,202 - 64,317,900 (-)NCBI
Vero_WHO_p1.0NW_02366605565,810,334 - 66,103,813 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007989715   ⟹   XP_007987906
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12564,024,342 - 64,317,894 (-)NCBI
Vero_WHO_p1.0NW_02366605565,810,334 - 66,103,809 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037986017   ⟹   XP_037841945
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605565,810,334 - 66,103,810 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007987898 (Get FASTA)   NCBI Sequence Viewer  
  XP_007987902 (Get FASTA)   NCBI Sequence Viewer  
  XP_007987906 (Get FASTA)   NCBI Sequence Viewer  
  XP_037841945 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006900.1
RefSeq Acc Id: XP_007987898   ⟸   XM_007989707
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007987906   ⟸   XM_007989715
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007987902   ⟸   XM_007989711
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCSAP00000006900   ⟸   ENSCSAT00000008767
RefSeq Acc Id: XP_037841945   ⟸   XM_037986017
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010678 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008767.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  PBX UniProtKB/TrEMBL
  TALE_homeobox UniProtKB/TrEMBL
NCBI Gene PBX1 ENTREZGENE
PANTHER HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
  PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1 UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  PBC UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  PBC UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A0D9RE61_CHLSB UniProtKB/TrEMBL