RAB6A (RAB6A, member RAS oncogene family) - Rat Genome Database

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Gene: RAB6A (RAB6A, member RAS oncogene family) Chlorocebus sabaeus
Analyze
Symbol: RAB6A
Name: RAB6A, member RAS oncogene family
RGD ID: 18642385
Description: ENCODES a protein that exhibits ATPase activator activity (ortholog); ATPase binding (ortholog); GTP binding (ortholog); INVOLVED IN peptidyl-cysteine methylation (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); intellectual disability (ortholog); FOUND IN presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-6A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,923,071 - 65,020,279 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,922,496 - 65,020,207 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604360,865,453 - 60,963,442 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RAB6A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,923,071 - 65,020,279 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,922,496 - 65,020,207 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604360,865,453 - 60,963,442 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAB6A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381173,675,638 - 73,761,074 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1173,675,638 - 73,761,137 (-)EnsemblGRCh38hg38GRCh38
GRCh371173,386,683 - 73,472,119 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361173,064,331 - 73,149,849 (-)NCBINCBI36Build 36hg18NCBI36
Build 341173,064,332 - 73,149,849NCBI
Celera1170,692,067 - 70,777,822 (-)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1169,682,483 - 69,767,815 (-)NCBIHuRef
CHM1_11173,270,356 - 73,355,857 (-)NCBICHM1_1
T2T-CHM13v2.01173,604,789 - 73,690,219 (-)NCBIT2T-CHM13v2.0
Rab6a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397100,256,778 - 100,290,475 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7100,256,617 - 100,290,475 (+)EnsemblGRCm39 Ensembl
GRCm387100,607,575 - 100,641,268 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7100,607,410 - 100,641,268 (+)EnsemblGRCm38mm10GRCm38
MGSCv377107,756,100 - 107,789,782 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367100,481,850 - 100,515,722 (+)NCBIMGSCv36mm8
Celera7100,946,742 - 100,980,482 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.36NCBI
Rab6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81164,370,033 - 164,422,324 (+)NCBIGRCr8
mRatBN7.21154,957,870 - 155,008,922 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,958,189 - 154,996,715 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1162,950,084 - 162,989,099 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01170,130,189 - 170,169,205 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01163,007,327 - 163,046,501 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01165,624,973 - 165,664,201 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,625,058 - 165,664,192 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,826,220 - 171,865,438 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,041,088 - 158,080,222 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11158,144,599 - 158,156,906 (+)NCBI
Celera1153,041,208 - 153,080,201 (+)NCBICelera
Cytogenetic Map1q32NCBI
Rab6a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541417,758,071 - 17,806,727 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541417,758,071 - 17,806,727 (+)NCBIChiLan1.0ChiLan1.0
RAB6A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2974,619,745 - 74,705,513 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11175,663,918 - 75,749,696 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,751,163 - 68,837,324 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,063,655 - 72,148,144 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,063,663 - 72,148,144 (-)Ensemblpanpan1.1panPan2
RAB6A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12124,489,653 - 24,578,212 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2124,492,359 - 24,576,524 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2124,239,195 - 24,343,629 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02124,679,351 - 24,784,291 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2124,699,371 - 24,839,863 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12124,474,127 - 24,578,595 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02124,674,207 - 24,779,068 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02124,589,401 - 24,694,514 (+)NCBIUU_Cfam_GSD_1.0
Rab6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494761,240,783 - 61,307,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364982,839,834 - 2,907,227 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364982,840,141 - 2,907,227 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB6A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl98,137,672 - 8,199,079 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.198,137,901 - 8,199,212 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.298,926,789 - 8,988,311 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rab6a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248173,241,323 - 3,307,269 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248173,241,636 - 3,307,331 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAB6A
1713 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000002094   ⟹   ENSCSAP00000000420
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl164,922,496 - 65,020,207 (-)Ensembl
RefSeq Acc Id: XM_008020110   ⟹   XP_008018301
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,923,071 - 65,020,279 (-)NCBI
Vero_WHO_p1.0NW_02366604360,865,487 - 60,963,442 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020111   ⟹   XP_008018302
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,923,071 - 65,020,279 (-)NCBI
Vero_WHO_p1.0NW_02366604360,865,453 - 60,963,442 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008018301 (Get FASTA)   NCBI Sequence Viewer  
  XP_008018302 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000420
  ENSCSAP00000000420.1
RefSeq Acc Id: XP_008018301   ⟸   XM_008020110
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QVN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008018302   ⟸   XM_008020111
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000000420   ⟸   ENSCSAT00000002094


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004062 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002094.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rab UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report csab:103248019 UniProtKB/TrEMBL
NCBI Gene RAB6A ENTREZGENE
PANTHER RAS-RELATED PROTEIN RAB UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9QVN1 ENTREZGENE, UniProtKB/TrEMBL