ANKS4B (ankyrin repeat and sterile alpha motif domain containing 4B) - Rat Genome Database

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Gene: ANKS4B (ankyrin repeat and sterile alpha motif domain containing 4B) Chlorocebus sabaeus
Analyze
Symbol: ANKS4B
Name: ankyrin repeat and sterile alpha motif domain containing 4B
RGD ID: 18606629
Description: INVOLVED IN protein localization to microvillus (ortholog); protein-containing complex assembly (ortholog); response to endoplasmic reticulum stress (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN brush border (ortholog); endoplasmic reticulum membrane (ortholog); microvillus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ankyrin repeat and SAM domain-containing protein 4B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1519,347,736 - 19,380,959 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl519,358,962 - 19,380,332 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606810,500,124 - 10,521,156 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ANKS4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1519,347,736 - 19,380,959 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl519,358,962 - 19,380,332 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606810,500,124 - 10,521,156 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ANKS4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381621,233,699 - 21,253,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1621,233,699 - 21,253,850 (+)EnsemblGRCh38hg38GRCh38
GRCh371621,245,020 - 21,265,171 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361621,152,517 - 21,171,251 (+)NCBINCBI36Build 36hg18NCBI36
Celera1620,559,328 - 20,578,058 (+)NCBICelera
Cytogenetic Map16p12.2NCBI
HuRef1619,780,267 - 19,798,999 (+)NCBIHuRef
CHM1_11621,332,353 - 21,351,089 (+)NCBICHM1_1
T2T-CHM13v2.01621,168,996 - 21,189,143 (+)NCBIT2T-CHM13v2.0
Anks4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397119,773,081 - 119,782,939 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7119,773,081 - 119,784,809 (+)EnsemblGRCm39 Ensembl
GRCm387120,173,858 - 120,183,716 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7120,173,858 - 120,185,586 (+)EnsemblGRCm38mm10GRCm38
MGSCv377127,317,372 - 127,327,230 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367119,965,025 - 119,974,863 (+)NCBIMGSCv36mm8
Celera7120,083,279 - 120,093,146 (+)NCBICelera
Cytogenetic Map7F2NCBI
cM Map764.45NCBI
Anks4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,934,528 - 183,989,127 (+)NCBIGRCr8
mRatBN7.21174,534,195 - 174,557,798 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1174,547,473 - 174,557,797 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1182,872,512 - 182,882,615 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01190,058,556 - 190,068,657 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,784,909 - 182,795,235 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,940,305 - 189,942,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,940,291 - 189,942,112 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01196,869,693 - 196,871,501 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1172,297,007 - 172,306,740 (+)NCBICelera
Cytogenetic Map1q36NCBI
Anks4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955493428,895 - 440,379 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955493429,339 - 439,456 (+)NCBIChiLan1.0ChiLan1.0
ANKS4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21822,406,254 - 22,421,664 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11626,926,784 - 26,942,201 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01617,154,209 - 17,170,120 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11621,267,573 - 21,283,015 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1621,267,573 - 21,283,015 (+)Ensemblpanpan1.1panPan2
ANKS4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1624,209,125 - 24,230,355 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl624,209,125 - 24,267,993 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha625,646,863 - 25,683,978 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0624,360,462 - 24,397,584 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl624,358,101 - 24,419,328 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1624,163,860 - 24,200,973 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0624,057,504 - 24,094,624 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0624,442,579 - 24,480,050 (-)NCBIUU_Cfam_GSD_1.0
Anks4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344118,325,830 - 118,339,050 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365016,423,719 - 6,435,835 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365016,423,719 - 6,436,639 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKS4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl324,828,224 - 24,852,764 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1324,836,446 - 24,852,816 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2325,642,959 - 25,654,471 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Anks4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,289,623 - 7,315,717 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,287,514 - 7,316,577 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 11 11
Below cutoff 18 7 38

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007987519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000005396   ⟹   ENSCSAP00000003618
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl519,358,962 - 19,380,332 (+)Ensembl
RefSeq Acc Id: XM_007987519   ⟹   XP_007985710
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1519,347,736 - 19,380,959 (+)NCBI
Vero_WHO_p1.0NW_02366606810,500,124 - 10,521,156 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007985710 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003618.1
Reference Protein Sequences
RefSeq Acc Id: XP_007985710   ⟸   XM_007987519
- UniProtKB: A0A0D9R4S9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000003618   ⟸   ENSCSAT00000005396


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007352 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005396.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
InterPro ANKS4B_SAM UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
KEGG Report csab:103229495 UniProtKB/TrEMBL
NCBI Gene ANKS4B ENTREZGENE
PANTHER ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 4B UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
UniProt A0A0D9R4S9 ENTREZGENE, UniProtKB/TrEMBL