LRRTM3 (leucine rich repeat transmembrane neuronal 3) - Rat Genome Database

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Gene: LRRTM3 (leucine rich repeat transmembrane neuronal 3) Chlorocebus sabaeus
Analyze
Symbol: LRRTM3
Name: leucine rich repeat transmembrane neuronal 3
RGD ID: 18588238
Description: INVOLVED IN positive regulation of amyloid-beta formation (ortholog); positive regulation of synapse assembly (ortholog); ASSOCIATED WITH arrhythmogenic right ventricular dysplasia 13 (ortholog); autism spectrum disorder (ortholog); Autosomal Dominant Intellectual Developmental Disorder 70 (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat transmembrane neuronal protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1964,260,513 - 64,435,277 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604825,071,912 - 25,246,681 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LRRTM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1964,260,513 - 64,435,277 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604825,071,912 - 25,246,681 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LRRTM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381066,926,036 - 67,101,551 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1066,926,036 - 67,101,551 (+)EnsemblGRCh38hg38GRCh38
GRCh371068,685,794 - 68,861,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361068,355,798 - 68,530,873 (+)NCBINCBI36Build 36hg18NCBI36
Build 341068,355,818 - 68,529,072NCBI
Celera1061,961,031 - 62,136,119 (+)NCBICelera
Cytogenetic Map10q21.3NCBI
HuRef1062,684,879 - 62,859,970 (+)NCBIHuRef
CHM1_11068,967,601 - 69,142,679 (+)NCBICHM1_1
T2T-CHM13v2.01067,789,258 - 67,964,743 (+)NCBIT2T-CHM13v2.0
Lrrtm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391063,764,276 - 63,926,034 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1063,764,251 - 63,926,056 (-)EnsemblGRCm39 Ensembl
GRCm381063,928,497 - 64,090,255 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1063,928,472 - 64,090,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv371063,391,245 - 63,553,003 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361063,323,854 - 63,485,612 (-)NCBIMGSCv36mm8
Celera1065,025,713 - 65,187,599 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.57NCBI
Lrrtm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82024,514,304 - 24,688,322 (+)NCBIGRCr8
mRatBN7.22024,515,627 - 24,689,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2024,515,627 - 24,689,669 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2025,232,288 - 25,407,794 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02024,585,290 - 24,760,796 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02025,149,771 - 25,326,595 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02025,990,304 - 26,163,656 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2025,990,304 - 26,163,656 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02028,060,837 - 28,233,801 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42026,343,897 - 26,518,838 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12026,530,218 - 26,532,637 (-)NCBI
Celera2025,840,823 - 26,013,166 (+)NCBICelera
Cytogenetic Map20p11NCBI
Lrrtm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542519,480,907 - 19,654,804 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542519,480,944 - 19,657,178 (+)NCBIChiLan1.0ChiLan1.0
LRRTM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2879,081,050 - 79,273,026 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11079,086,355 - 79,278,350 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01063,407,003 - 63,594,210 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11065,721,854 - 65,895,122 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1065,722,425 - 65,893,608 (+)Ensemblpanpan1.1panPan2
LRRTM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1418,320,720 - 18,485,863 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl418,321,084 - 18,481,131 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha418,449,353 - 18,611,927 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0418,591,439 - 18,754,088 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl418,591,459 - 18,754,738 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1418,476,844 - 18,638,825 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0418,693,637 - 18,855,992 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0419,039,648 - 19,202,050 (+)NCBIUU_Cfam_GSD_1.0
Lrrtm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721362,534,045 - 62,694,508 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936925330,399 - 493,632 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936925330,424 - 492,052 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRTM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1470,172,746 - 70,180,777 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11470,172,460 - 70,352,073 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21476,064,496 - 76,242,177 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Lrrtm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247541,348,129 - 1,496,259 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247541,348,448 - 1,499,649 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007963299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_007963299   ⟹   XP_007961490
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1964,260,513 - 64,435,277 (-)NCBI
Vero_WHO_p1.0NW_02366604825,071,912 - 25,246,681 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007961490 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003740.1
Reference Protein Sequences
RefSeq Acc Id: XP_007961490   ⟸   XM_007963299
- UniProtKB: A0A0D9R551 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007477 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005524.1 UniProtKB/TrEMBL
Gene3D-CATH Ribonuclease Inhibitor UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
NCBI Gene LRRTM3 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 3 UniProtKB/TrEMBL
  SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A0D9R551 ENTREZGENE, UniProtKB/TrEMBL