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Gene: FDCSP (follicular dendritic cell secreted protein) Chlorocebus sabaeus

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Symbol:

FDCSP

Name:

follicular dendritic cell secreted protein

RGD ID:

18587288

Description:

ENCODES a protein that exhibits hydroxyapatite binding (ortholog); INVOLVED IN isotype switching to IgD isotypes (ortholog); isotype switching to IgE isotypes (ortholog); isotype switching to IgG isotypes (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

follicular dendritic cell secreted peptide; LOC103235737

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	18,711,145 - 18,721,926 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	18,716,973 - 18,721,350 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666084	4,202,678 - 4,211,798 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

isotype switching to IgD isotypes (ISO)

isotype switching to IgE isotypes (ISO)

isotype switching to IgG isotypes (ISO)

mucosal immune response (ISO)

negative regulation of isotype switching to IgA isotypes (ISO)

positive regulation of B cell chemotaxis (ISO)

Cellular Component

collagen-containing extracellular matrix (ISO)

Molecular Function

hydroxyapatite binding (ISO)

protein binding (ISO)

References

Genomics

Comparative Map Data

FDCSP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	18,711,145 - 18,721,926 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	18,716,973 - 18,721,350 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666084	4,202,678 - 4,211,798 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

FDCSP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	70,226,124 - 70,235,252 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	70,226,124 - 70,235,252 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	71,091,841 - 71,100,969 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	71,126,404 - 71,135,558 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	71,272,574 - 71,281,729	NCBI
Celera	4	68,449,575 - 68,458,729 (+)	NCBI		Celera
Cytogenetic Map	4	q13.3	NCBI
HuRef	4	66,894,015 - 66,903,196 (+)	NCBI		HuRef
CHM1_1	4	71,128,208 - 71,137,390 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	73,565,445 - 73,574,935 (+)	NCBI		T2T-CHM13v2.0

Fdcsp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	88,056,638 - 88,062,030 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	88,056,638 - 88,062,030 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	87,908,779 - 87,914,171 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	87,908,779 - 87,914,171 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	88,337,804 - 88,343,196 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	88,983,365 - 88,988,729 (+)	NCBI		MGSCv36	mm8
MGSCv36	5	87,513,203 - 87,518,567 (+)	NCBI		MGSCv36	mm8
Cytogenetic Map	5	E1	NCBI
cM Map	5	45.0	NCBI

Fdcsp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	20,447,761 - 20,453,227 (-)	NCBI		GRCr8
mRatBN7.2	14	20,169,691 - 20,173,983 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	20,169,691 - 20,173,983 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	20,100,114 - 20,104,407 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	21,419,000 - 21,423,293 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	20,149,774 - 20,154,066 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	21,818,999 - 21,823,687 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	21,819,395 - 21,823,687 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	21,729,348 - 21,733,772 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	21,690,466 - 21,694,758 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	21,690,465 - 21,694,758 (-)	NCBI
Celera	14	19,572,307 - 19,576,599 (-)	NCBI		Celera
Cytogenetic Map	14	p21	NCBI

FDCSP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	59,847,452 - 59,857,051 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	60,044,013 - 60,053,618 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	53,988,378 - 53,998,028 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	60,331,941 - 60,341,589 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	60,331,243 - 60,341,647 (-)	Ensembl	panpan1.1		panPan2

Fdcsp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624890	1,641,993 - 1,645,026 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in FDCSP
336 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
23	21	17	33	33	7	5

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007998778	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007998779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007998781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000002933 ⟹ ENSCSAP00000001223

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	7	18,716,973 - 18,721,350 (+)	Ensembl

RefSeq Acc Id:

XM_007998778 ⟹ XP_007996969

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	7	18,711,147 - 18,721,390 (+)	NCBI
Vero_WHO_p1.0	NW_023666084	4,202,678 - 4,211,798 (-)	NCBI

Sequence:

show sequence

GAAGTTCTCAAAAAAACTTAGCTGTTATTATTTTTCTGAGTTCCCTTGAGAACTGATTTCTAGA
AAAAATAAAAAGAAGAAAAGGGACTTTGATGCACTACTACTACAATCTGGACTATATAACCTCT
TTTGAAGTAGAACTCAATAATAGAATATTTTTGAAAGCTCTCAAATGAGTTAAAGCTCAAATTT
TATGACTCTTGAAAATGGCATATACAATATGCATGCATATTTAAGGTAATTCTTGAATGTTTTG
TGGGCTCTAGTTTCTAGTCCAGCACTTAATGATGATACCCTTTCTGTGCAAGTGAATTTTCAGT
TGAGAAACAGAGTATAGTGTTCCATAAGGTAAACAAGATGCTGTGGTGCTCCAAAAATACAATT
CACTCATCTATGAAGCTCTAATCCTGATAATAAAATGAAGAAGCTGAACGCAGAACCATGCAAA
AGATTTTAATCCCATCTTTAACGATTTTTAGATTTTTTATTTTCTTAAGATTCCAGCACTATCA
AATATGCTTTGCAATAGATTGTTATCAATACCAGTAAAATGCTTGGAGGTATTTTAAATTGTGG
GAAGTGAAGGAAAAAAATTGTGAGAGTAGACAATGGAACAACAACATGTAAAGTGATAAGCTTC
AAATATACGAGACACAAAATTTGGAGAAAAAAACCACAGAAGATTTTGGTATTTGGTAGTTTCT
ATGAAACTAGACATTGGTTATTCCCCAATTTCAACATATTGTGATAGTTGATGAGTAATAACTG
ATCCTATGGGAGAAGCCTTTAAGCCACAGATTTCTCCACTCCATTATACCTTCGAGTATATAAA
ACAGCTGCAATATTCCAGGGCCAGACACTCTCCCTTTCTAACAGCGTCGGAGACAAAGAACTGA
CTGAAACGTTTGAGATGAAGAAAGTTCTCCTTCTGATCACAGCCATCCTGGCAGTGGCTGTTGG
TTTCCCAGTCTCTCAAGACCAGGAACGAGAAAAAAGAAGTGTCAGTGACAGCGATGAATTTTTT
TCAGGATTTCTTGCGTTCCCTTACCCATATCCATTTCGCCCATTTCCACCAATTCCATATCCAA
GATTTCCAAGGTTTGGACGTAGTTTTCCTGTTCCAATACCTGAATCTGGCCCTACAACTCCCCT
TCCTAGTGAAAGTAAACAAGAATGAGAAGTCACAATAAAATTGAAGATGAAATATGTGGTCACC
TAAAATTAAATGTGAGCCACTTCTTTGAAGAATCAAAATTCCTGTTAATGAAAGAATAACAAAT
GTAATTGAAATAGCACACAGCATTCTCTATTCAATATCTTTAGTGATCTTCTTTAATAAACATG
AAAGCAAAGGTCTTGGTTTCTTAATTTCCACAAATTCCATGATAAGTACTTGATTTGTTTTCAA
TCTTCAGCAATATCTTGAAGAAGGAAGAGGTGGCAGATGGTGACAATAACAAACTGTCCTACAG
CATGTGACAAAAGTCATCCAACAAGATTCTACTTGCACAATAAGCCTTTCAGTGGGTCACAATG
ACTACCTTTGTCTCCACAAGCTGATTATCAGGAAATTAGAAAAATTCTCTTTGAATAAAGATTG
TGTTTCTTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007996969	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000001223.1

RefSeq Acc Id:	XP_007996969 ⟸ XM_007998778
- UniProtKB:	A0A0D9QXY4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000001223 ⟸ ENSCSAT00000002933

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004899	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002933.1	UniProtKB/TrEMBL
InterPro	FDC-SP	UniProtKB/TrEMBL
NCBI Gene	FDCSP	ENTREZGENE
Pfam	FDC-SP	UniProtKB/TrEMBL
UniProt	A0A0D9QXY4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-09	FDCSP	follicular dendritic cell secreted protein	LOC103235737	follicular dendritic cell secreted protein	Symbol and/or name change	5135510	APPROVED
2020-12-08	LOC103235737	follicular dendritic cell secreted protein	FDCSP	follicular dendritic cell secreted protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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