GPR68 (G protein-coupled receptor 68) - Rat Genome Database

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Gene: GPR68 (G protein-coupled receptor 68) Chlorocebus sabaeus
Analyze
Symbol: GPR68
Name: G protein-coupled receptor 68
RGD ID: 18567338
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN cellular response to pH (ortholog); insulin secretion (ortholog); monocyte differentiation (ortholog); ASSOCIATED WITH achondrogenesis type IA (ortholog); amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 2A6 (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ovarian cancer G-protein coupled receptor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12468,998,721 - 69,027,237 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2468,998,805 - 68,999,902 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605356,253,057 - 56,281,240 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GPR68
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12468,998,721 - 69,027,237 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2468,998,805 - 68,999,902 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605356,253,057 - 56,281,240 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GPR68
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381491,232,532 - 91,270,790 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1491,232,532 - 91,253,925 (-)EnsemblGRCh38hg38GRCh38
GRCh371491,698,876 - 91,720,224 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361490,768,629 - 90,789,977 (-)NCBINCBI36Build 36hg18NCBI36
Build 341490,769,964 - 90,790,022NCBI
Celera1471,747,337 - 71,768,677 (-)NCBICelera
Cytogenetic Map14q32.11NCBI
HuRef1471,875,167 - 71,896,408 (-)NCBIHuRef
CHM1_11491,636,649 - 91,657,972 (-)NCBICHM1_1
T2T-CHM13v2.01485,458,030 - 85,496,278 (-)NCBIT2T-CHM13v2.0
Gpr68
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912100,842,941 - 100,874,457 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12100,842,941 - 100,874,457 (-)EnsemblGRCm39 Ensembl
GRCm3812100,876,679 - 100,908,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12100,876,682 - 100,908,198 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712102,114,892 - 102,146,408 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612101,277,735 - 101,288,931 (-)NCBIMGSCv36mm8
Celera12102,103,729 - 102,135,412 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.1NCBI
Gpr68
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86125,865,205 - 125,895,674 (-)NCBIGRCr8
mRatBN7.26120,135,620 - 120,166,089 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,135,436 - 120,166,089 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6120,290,512 - 120,320,967 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06120,587,199 - 120,617,654 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06119,922,046 - 119,952,502 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06124,874,151 - 124,903,949 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,874,151 - 124,876,710 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06134,095,815 - 134,123,783 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46125,134,284 - 125,174,033 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16125,139,362 - 125,140,542 (-)NCBI
Celera6117,663,888 - 117,694,277 (-)NCBICelera
Cytogenetic Map6q32NCBI
Gpr68
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543813,555,379 - 13,559,465 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543813,553,770 - 13,575,093 (-)NCBIChiLan1.0ChiLan1.0
GPR68
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21592,382,587 - 92,414,691 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11491,599,095 - 91,631,206 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01471,859,025 - 71,891,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11491,206,261 - 91,227,264 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1491,207,679 - 91,208,806 (-)Ensemblpanpan1.1panPan2
GPR68
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1862,090,050 - 62,108,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl862,092,135 - 62,093,217 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha861,668,237 - 61,696,572 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0862,362,350 - 62,390,680 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl862,362,354 - 62,374,835 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1862,042,914 - 62,071,212 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0862,092,632 - 62,120,928 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0862,421,632 - 62,450,098 (-)NCBIUU_Cfam_GSD_1.0
Gpr68
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864013,789,934 - 13,811,716 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648818,259,866 - 18,260,993 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648818,257,765 - 18,278,530 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR68
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7112,885,163 - 112,904,246 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17112,885,160 - 112,904,214 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27119,457,230 - 119,485,333 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Gpr68
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473411,360,053 - 11,368,757 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473411,338,233 - 11,370,239 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000019668   ⟹   ENSCSAP00000019077
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2468,998,805 - 68,999,902 (-)Ensembl
RefSeq Acc Id: XM_007987593   ⟹   XP_007985784
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12468,998,721 - 69,009,685 (-)NCBI
Vero_WHO_p1.0NW_02366605356,253,057 - 56,263,753 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007987594   ⟹   XP_007985785
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12468,998,721 - 69,027,237 (-)NCBI
Vero_WHO_p1.0NW_02366605356,253,057 - 56,281,240 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007987595   ⟹   XP_007985786
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12468,998,721 - 69,007,357 (-)NCBI
Vero_WHO_p1.0NW_02366605356,253,057 - 56,262,680 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007987596   ⟹   XP_007985787
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12468,998,721 - 69,009,685 (-)NCBI
Vero_WHO_p1.0NW_02366605356,253,057 - 56,263,754 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007985784 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985785 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985786 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985787 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000019077
  ENSCSAP00000019077.1
RefSeq Acc Id: XP_007985785   ⟸   XM_007987594
- UniProtKB: A0A0D9SDY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007985787   ⟸   XM_007987596
- UniProtKB: A0A0D9SDY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007985784   ⟸   XM_007987593
- UniProtKB: A0A0D9SDY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007985786   ⟸   XM_007987595
- UniProtKB: A0A0D9SDY8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000019077   ⟸   ENSCSAT00000019668


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019578 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019668.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  OGR1_rcpt UniProtKB/TrEMBL
NCBI Gene GPR68 ENTREZGENE
PANTHER LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR UniProtKB/TrEMBL
  OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OGR1RECEPTOR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9SDY8 ENTREZGENE, UniProtKB/TrEMBL