TREML2 (triggering receptor expressed on myeloid cells like 2) - Rat Genome Database

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Gene: TREML2 (triggering receptor expressed on myeloid cells like 2) Chlorocebus sabaeus
Analyze
Symbol: TREML2
Name: triggering receptor expressed on myeloid cells like 2
RGD ID: 18489288
Description: ENCODES a protein that exhibits signaling receptor activity (inferred); INVOLVED IN T cell activation (inferred); ASSOCIATED WITH infantile Refsum disease (ortholog); Zellweger syndrome (ortholog); FOUND IN cell surface (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103221522
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11730,949,709 - 30,962,348 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1730,950,860 - 30,959,703 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604441,197,970 - 41,209,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TREML2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11730,949,709 - 30,962,348 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1730,950,860 - 30,959,703 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604441,197,970 - 41,209,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TREML2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38641,189,749 - 41,201,149 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl641,189,749 - 41,201,149 (-)EnsemblGRCh38hg38GRCh38
GRCh37641,157,487 - 41,168,887 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36641,266,206 - 41,276,902 (-)NCBINCBI36Build 36hg18NCBI36
Build 34641,266,205 - 41,276,902NCBI
Celera642,710,254 - 42,721,629 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef640,875,346 - 40,886,723 (-)NCBIHuRef
CHM1_1641,160,464 - 41,171,828 (-)NCBICHM1_1
T2T-CHM13v2.0641,018,309 - 41,029,701 (-)NCBIT2T-CHM13v2.0
Treml2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391748,606,419 - 48,619,562 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1748,606,526 - 48,619,561 (+)EnsemblGRCm39 Ensembl
GRCm381748,299,390 - 48,312,534 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1748,299,498 - 48,312,533 (+)EnsemblGRCm38mm10GRCm38
MGSCv371748,439,363 - 48,451,859 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361747,765,507 - 47,776,716 (+)NCBIMGSCv36mm8
Celera1751,729,007 - 51,741,509 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.99NCBI
Treml2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,192,292 - 20,202,981 (-)NCBIGRCr8
mRatBN7.2912,694,453 - 12,705,379 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl912,694,697 - 12,705,324 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0914,659,967 - 14,668,313 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl914,660,738 - 14,668,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0913,581,327 - 13,590,040 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.498,107,688 - 8,115,759 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera910,468,458 - 10,476,804 (-)NCBICelera
Cytogenetic Map9q12NCBI
Treml2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554377,812,005 - 7,824,344 (-)NCBIChiLan1.0ChiLan1.0
TREML2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2555,674,472 - 55,685,958 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1651,544,432 - 51,555,915 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0640,766,713 - 40,778,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1642,075,101 - 42,086,477 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl642,075,101 - 42,086,477 (-)Ensemblpanpan1.1panPan2
TREML2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1129,948,309 - 9,958,991 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl129,950,133 - 9,959,478 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha129,978,286 - 9,988,881 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01210,427,899 - 10,438,498 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1210,428,677 - 10,438,672 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1129,959,997 - 9,970,595 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01210,041,737 - 10,052,263 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,136,772 - 10,147,368 (-)NCBIUU_Cfam_GSD_1.0
Treml2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494645,326,414 - 45,335,058 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647618,625,573 - 18,632,228 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647618,625,573 - 18,632,228 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TREML2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl736,482,058 - 36,493,906 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1736,478,339 - 36,494,348 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2741,779,258 - 41,786,511 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Treml2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475417,613,812 - 17,623,436 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
46 34 20 36 36 30 18

Sequence


Ensembl Acc Id: ENSCSAT00000009322   ⟹   ENSCSAP00000007443
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1730,950,860 - 30,959,703 (+)Ensembl
RefSeq Acc Id: XM_007972636   ⟹   XP_007970827
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11730,949,709 - 30,962,348 (+)NCBI
Vero_WHO_p1.0NW_02366604441,197,970 - 41,209,962 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007970827 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007443.1
RefSeq Acc Id: XP_007970827   ⟸   XM_007972636
- UniProtKB: A0A0D9RFQ4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000007443   ⟸   ENSCSAT00000009322


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011246 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009322.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Immune_rcpt_domain UniProtKB/TrEMBL
NCBI Gene LOC103221522 ENTREZGENE
PANTHER TREM-LIKE TRANSCRIPT 2 PROTEIN UniProtKB/TrEMBL
  TREM-LIKE TRANSCRIPT PROTEIN UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0D9RFQ4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 TREML2  triggering receptor expressed on myeloid cells like 2  LOC103221522  trem-like transcript 2 protein  Symbol and/or name change 5135510 APPROVED