FAM53B (family with sequence similarity 53 member B) - Rat Genome Database

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Gene: FAM53B (family with sequence similarity 53 member B) Chlorocebus sabaeus
Analyze
Symbol: FAM53B
Name: family with sequence similarity 53 member B
RGD ID: 18403428
Description: INVOLVED IN positive regulation of canonical Wnt signaling pathway (inferred); protein import into nucleus (inferred); regulation of canonical Wnt signaling pathway (inferred); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein FAM53B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19117,274,491 - 117,402,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9117,281,516 - 117,365,393 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604878,629,441 - 78,754,492 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FAM53B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19117,274,491 - 117,402,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9117,281,516 - 117,365,393 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604878,629,441 - 78,754,492 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FAM53B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810124,619,292 - 124,744,378 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10124,619,292 - 124,744,378 (-)EnsemblGRCh38hg38GRCh38
GRCh3710126,307,861 - 126,432,947 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610126,297,853 - 126,422,920 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410126,297,852 - 126,422,920NCBI
Celera10120,081,758 - 120,206,847 (-)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10119,994,456 - 120,081,985 (-)NCBIHuRef
CHM1_110126,589,691 - 126,714,741 (-)NCBICHM1_1
T2T-CHM13v2.010125,500,348 - 125,625,386 (-)NCBIT2T-CHM13v2.0
Fam53b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397132,313,813 - 132,429,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7132,313,811 - 132,415,615 (-)EnsemblGRCm39 Ensembl
GRCm387132,712,084 - 132,813,848 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7132,712,082 - 132,813,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv377139,903,767 - 140,004,879 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367132,550,427 - 132,651,539 (-)NCBIMGSCv36mm8
Celera7132,517,316 - 132,618,775 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map776.31NCBI
Fam53b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,930,170 - 197,021,290 (-)NCBIGRCr8
mRatBN7.21187,500,061 - 187,591,186 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1187,500,066 - 187,591,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1195,850,220 - 195,941,337 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01203,028,988 - 203,120,140 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01195,702,117 - 195,793,264 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01204,714,468 - 204,805,738 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1204,714,473 - 204,817,080 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01211,707,719 - 211,798,528 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41192,180,087 - 192,271,253 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11192,333,458 - 192,431,090 (-)NCBI
Celera1185,244,527 - 185,335,599 (-)NCBICelera
Cytogenetic Map1q41NCBI
Fam53b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554772,609,431 - 2,725,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554772,609,431 - 2,725,001 (-)NCBIChiLan1.0ChiLan1.0
FAM53B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28136,466,116 - 136,591,759 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110136,471,467 - 136,597,030 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010121,175,032 - 121,300,276 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110125,443,925 - 125,584,509 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10125,443,925 - 125,585,392 (-)Ensemblpanpan1.1panPan2
FAM53B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12833,961,810 - 34,077,075 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2833,933,605 - 34,081,090 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2834,019,966 - 34,126,040 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02834,515,444 - 34,621,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2834,491,114 - 34,659,251 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12834,071,767 - 34,177,715 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02834,063,869 - 34,169,839 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02834,315,417 - 34,421,382 (-)NCBIUU_Cfam_GSD_1.0
Fam53b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721312,558,977 - 12,690,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648612,870,753 - 13,002,456 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648612,870,773 - 12,983,172 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM53B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14134,002,228 - 134,082,462 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114134,002,226 - 134,135,397 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214145,501,642 - 145,619,512 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Fam53b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473722,411,728 - 22,495,801 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473722,355,112 - 22,495,801 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FAM53B
3240 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000002555   ⟹   ENSCSAP00000000857
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl9117,281,516 - 117,365,393 (-)Ensembl
RefSeq Acc Id: XM_007964346   ⟹   XP_007962537
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.19117,277,554 - 117,402,965 (-)NCBI
Vero_WHO_p1.0NW_02366604878,629,441 - 78,754,492 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007962537 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000857.1
RefSeq Acc Id: XP_007962537   ⟸   XM_007964346
- UniProtKB: A0A0D9QWW8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000000857   ⟸   ENSCSAT00000002555


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004523 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002555.1 UniProtKB/TrEMBL
InterPro FAM53 UniProtKB/TrEMBL
KEGG Report csab:103216667 UniProtKB/TrEMBL
NCBI Gene FAM53B ENTREZGENE
PANTHER PROTEIN FAM53B UniProtKB/TrEMBL
  PTHR28567 UniProtKB/TrEMBL
Pfam FAM53 UniProtKB/TrEMBL
UniProt A0A0D9QWW8 ENTREZGENE, UniProtKB/TrEMBL