Fam53b (family with sequence similarity 53 member B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Fam53b (family with sequence similarity 53 member B) Ictidomys tridecemlineatus
Analyze
Symbol: Fam53b
Name: family with sequence similarity 53 member B
RGD ID: 12737159
Description: INVOLVED IN positive regulation of canonical Wnt signaling pathway (inferred); protein import into nucleus (inferred); regulation of canonical Wnt signaling pathway (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: family with sequence similarity 53 member B, transcript variant X1; family with sequence similarity 53 member B, transcript variant X2; family with sequence similarity 53 member B, transcript variant X3; family with sequence similarity 53 member B, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721312,558,977 - 12,690,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648612,870,753 - 13,002,456 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648612,870,773 - 12,983,172 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Fam53b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721312,558,977 - 12,690,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648612,870,753 - 13,002,456 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648612,870,773 - 12,983,172 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM53B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810124,619,292 - 124,744,378 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10124,619,292 - 124,744,378 (-)EnsemblGRCh38hg38GRCh38
GRCh3710126,307,861 - 126,432,947 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610126,297,853 - 126,422,920 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410126,297,852 - 126,422,920NCBI
Celera10120,081,758 - 120,206,847 (-)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10119,994,456 - 120,081,985 (-)NCBIHuRef
CHM1_110126,589,691 - 126,714,741 (-)NCBICHM1_1
T2T-CHM13v2.010125,500,348 - 125,625,386 (-)NCBIT2T-CHM13v2.0
Fam53b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397132,313,813 - 132,429,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7132,313,811 - 132,415,615 (-)EnsemblGRCm39 Ensembl
GRCm387132,712,084 - 132,813,848 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7132,712,082 - 132,813,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv377139,903,767 - 140,004,879 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367132,550,427 - 132,651,539 (-)NCBIMGSCv36mm8
Celera7132,517,316 - 132,618,775 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map776.31NCBI
Fam53b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,930,170 - 197,021,290 (-)NCBIGRCr8
mRatBN7.21187,500,061 - 187,591,186 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1187,500,066 - 187,591,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1195,850,220 - 195,941,337 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01203,028,988 - 203,120,140 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01195,702,117 - 195,793,264 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01204,714,468 - 204,805,738 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1204,714,473 - 204,817,080 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01211,707,719 - 211,798,528 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41192,180,087 - 192,271,253 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11192,333,458 - 192,431,090 (-)NCBI
Celera1185,244,527 - 185,335,599 (-)NCBICelera
Cytogenetic Map1q41NCBI
Fam53b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554772,609,431 - 2,725,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554772,609,431 - 2,725,001 (-)NCBIChiLan1.0ChiLan1.0
FAM53B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28136,466,116 - 136,591,759 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110136,471,467 - 136,597,030 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010121,175,032 - 121,300,276 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110125,443,925 - 125,584,509 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10125,443,925 - 125,585,392 (-)Ensemblpanpan1.1panPan2
FAM53B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12833,961,810 - 34,077,075 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2833,933,605 - 34,081,090 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2834,019,966 - 34,126,040 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02834,515,444 - 34,621,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2834,491,114 - 34,659,251 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12834,071,767 - 34,177,715 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02834,063,869 - 34,169,839 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02834,315,417 - 34,421,382 (-)NCBIUU_Cfam_GSD_1.0
FAM53B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14134,002,228 - 134,082,462 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114134,002,226 - 134,135,397 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214145,501,642 - 145,619,512 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FAM53B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19117,274,491 - 117,402,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9117,281,516 - 117,365,393 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604878,629,441 - 78,754,492 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam53b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473722,411,728 - 22,495,801 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473722,355,112 - 22,495,801 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000004523   ⟹   ENSSTOP00000004060
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648612,874,626 - 13,002,456 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000035360   ⟹   ENSSTOP00000026492
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648612,875,854 - 13,002,456 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000041240   ⟹   ENSSTOP00000028542
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648612,870,753 - 12,959,819 (-)Ensembl
RefSeq Acc Id: XM_013356549   ⟹   XP_013212003
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721312,578,126 - 12,690,525 (+)NCBI
SpeTri2.0NW_00493648612,870,773 - 12,983,172 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013356550   ⟹   XP_013212004
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721312,604,716 - 12,690,525 (+)NCBI
SpeTri2.0NW_00493648612,870,773 - 12,957,479 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040273832   ⟹   XP_040129766
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721312,558,977 - 12,690,525 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013212003   ⟸   XM_013356549
- UniProtKB: I3M4E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013212004   ⟸   XM_013356550
- UniProtKB: I3M4E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040129766   ⟸   XM_040273832
- UniProtKB: I3M4E7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000028542   ⟸   ENSSTOT00000041240
RefSeq Acc Id: ENSSTOP00000026492   ⟸   ENSSTOT00000035360
RefSeq Acc Id: ENSSTOP00000004060   ⟸   ENSSTOT00000004523


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004536 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004523.3 UniProtKB/TrEMBL
  ENSSTOT00000035360.1 UniProtKB/TrEMBL
  ENSSTOT00000041240.1 UniProtKB/TrEMBL
InterPro FAM53 UniProtKB/TrEMBL
NCBI Gene Fam53b ENTREZGENE
PANTHER PROTEIN FAM53B UniProtKB/TrEMBL
  PTHR28567 UniProtKB/TrEMBL
Pfam FAM53 UniProtKB/TrEMBL
UniProt A0A287CYV4_ICTTR UniProtKB/TrEMBL
  I3M4E7 ENTREZGENE, UniProtKB/TrEMBL