CRTAP (cartilage associated protein)

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Gene: CRTAP (cartilage associated protein) Chlorocebus sabaeus

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Symbol:

CRTAP

Name:

cartilage associated protein

RGD ID:

18392389

Description:

ENCODES a protein that exhibits collagen binding (inferred); INVOLVED IN peptidyl-proline hydroxylation to 3-hydroxy-L-proline (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); osteogenesis imperfecta (ortholog); FOUND IN endoplasmic reticulum (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC103241841

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	77,608,493 - 77,636,242 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	77,608,760 - 77,635,960 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	50,987,810 - 51,019,619 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

osteogenesis imperfecta (ISO)

osteogenesis imperfecta type 7 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

collagen fibril organization (IEA)

negative regulation of post-translational protein modification (IEA)

peptidyl-proline hydroxylation to 3-hydroxy-L-proline (ISO)

protein stabilization (IEA)

spermatogenesis (IEA)

Cellular Component

endoplasmic reticulum (IEA)

extracellular space (IEA)

Molecular Function

collagen binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CRTAP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	77,608,493 - 77,636,242 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	77,608,760 - 77,635,960 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	50,987,810 - 51,019,619 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CRTAP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	33,114,014 - 33,147,773 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	33,114,014 - 33,147,773 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	33,155,506 - 33,189,265 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	33,130,483 - 33,164,269 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	33,130,482 - 33,164,269	NCBI
Celera	3	33,098,553 - 33,132,585 (+)	NCBI		Celera
Cytogenetic Map	3	p22.3	NCBI
HuRef	3	33,088,585 - 33,093,213 (-)	NCBI		HuRef
CHM1_1	3	33,105,509 - 33,139,329 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	33,115,771 - 33,149,528 (+)	NCBI		T2T-CHM13v2.0

Crtap
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	114,204,204 - 114,219,743 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	114,204,202 - 114,219,743 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	114,375,131 - 114,390,712 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	114,375,134 - 114,390,675 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	114,284,249 - 114,299,830 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	114,223,836 - 114,239,368 (-)	NCBI		MGSCv36	mm8
Celera	9	114,846,559 - 114,862,195 (-)	NCBI		Celera
Cytogenetic Map	9	F3	NCBI
cM Map	9	64.39	NCBI

Crtap
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	122,926,117 - 122,945,843 (-)	NCBI		GRCr8
mRatBN7.2	8	114,047,929 - 114,067,636 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	114,047,933 - 114,067,631 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	119,664,008 - 119,684,195 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	117,863,271 - 117,883,459 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	115,706,053 - 115,726,233 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	122,394,451 - 122,402,198 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	122,417,532 - 122,421,384 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	121,719,062 - 121,734,324 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	8	121,695,467 - 121,715,067 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	118,765,925 - 118,773,673 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	8	113,306,491 - 113,314,398 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

Crtap
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955421	384,668 - 408,214 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955421	384,668 - 408,214 (+)	NCBI	ChiLan1.0	ChiLan1.0

CRTAP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	33,089,852 - 33,120,326 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	33,095,851 - 33,125,090 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	33,040,030 - 33,071,095 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	33,342,700 - 33,376,184 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	33,342,694 - 33,370,863 (+)	Ensembl	panpan1.1		panPan2

CRTAP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	3,694,695 - 3,723,119 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	3,698,407 - 3,722,800 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	3,736,004 - 3,767,088 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	3,951,805 - 3,982,905 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	3,958,025 - 3,982,886 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	3,786,542 - 3,817,624 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	3,913,837 - 3,944,928 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	3,887,433 - 3,918,531 (-)	NCBI		UU_Cfam_GSD_1.0

Crtap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	190,312,838 - 190,334,055 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	23,451,411 - 23,472,736 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	23,451,394 - 23,472,645 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CRTAP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	18,995,234 - 19,035,720 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	18,994,371 - 19,040,297 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Crtap
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624788	11,130,278 - 11,153,965 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624788	11,130,232 - 11,153,322 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008009390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000007495 ⟹ ENSCSAP00000005672

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	15	77,608,760 - 77,635,960 (+)	Ensembl

RefSeq Acc Id:

XM_008009390 ⟹ XP_008007581

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	15	77,608,493 - 77,636,242 (+)	NCBI
Vero_WHO_p1.0	NW_023666041	50,987,810 - 51,019,619 (+)	NCBI

Sequence:

show sequence

ATGAGCGGCGGAGCCCCATCACACGCATCAGCCTTCGTGAACCAGTGCGCAGCGCGCCGTACAC
GCGCACCCTCTCGGCGCTGGCAGCTGGCGCCCAGATCCCCCGGCTGGGTGGGGAGGAGCGGCCG
GACGGGGCGGGCCGGCAGCTGGCGTCCCCGCCCCGAAAGCATTCGGCCCGCCGCGTCGAGCCGT
CCTCTTTCCTTTCTTTCTCCCTCCCCTTTTCCCTTCCTTCGTCCCTTCCTTTCTTCCTTCCTTT
CGCCGGGCGCGATGGAGTCGGGGCGTCCGGGGGTCGCGGCGCTGTTGGCGCTGCTGTGCGTGGC
CTGTGCGCTGCGCGCCGGGCGCGCGCAGTACGAACGCTACAGCTTCCGCAGCTTCCCACGGGAC
GAGCTGATGCCGCTCGAGTCGGCCTACGGGCACGCGCTGGACAAGTATAGTGGGGAGCACTGGG
CTGAGAGCGTGGGCTACCTGGAGATCAGCCTGCGGCTGCACCGCCTGCTGCGCGACAGCGAGGC
CTTCTGCCACCGCAACTGCAGCGCCGCGCCGCAGCCCGAGCCCGCCTCCGGCCTCGCCAGCTAT
CCAGAGCTGCGCCTCTTCGGGGGCCTGCTGCGCCGCGCGCACTGCCTCAAGCGCTGCAAGCAAG
GCCTGCCAGCCTTCCGCCAGTCCCAGCCCAGCCGCGAGGTGCTGGCGGACTTCCAGCGCCGCGA
GCCCTACAAGTTCCTGCAGTTCGCCTACTTCAAGGCAAATAATCTCCCCAAAGCCATCGCAGCT
GCTCACACCTTTCTACTGAAGCATCCTGATGACGAAATGATGAAGAGGAACATGGCCTATTATA
AGAGCCTGCCTGGTGCCGAGGACTACATTAAAGACCTGGAAACCAAGTCGTAAGAGAGCCTGTT
CATCCGAGCAGTGCGAGCGTACAACGGTGAGAACTGGAGAACATCCATCACAGACATGGAGCTG
GCCCTTCCCGACTTCTTCAAAGCCTTTTACGAGTGTCTCGCGGCCTGTGAGGGTTCCAGGGAGA
TCAAGGACTTCAAGGATTTCTACCTTTCCATAGCAGATCATTATGTAGAAGTTCTGGAATGCAA
AATACAGTGTGAAGAGAACCTCACCCCAGTTATAGGAGGCTATCCAGTTGAGAAATTTGTGGCT
ACCATGTATCATTACTTGCAGTTTGCCTATTATAAGTTGAACGACCTGAAGAACGCAGCCCCCT
GCGCAGTCAGCTACCTGCTCTTTGATCAGAATGACAGGGTCATGCAGCAGAACCTGGTGTATTA
CCAGTACCACAGGGACACGTGGGGCCTCTCGGATGAGCACTTCCAGCCCAGACCTGAAGCAGTT
CAGTTCTTTAACGTGACCACACTCCAGAAGGAGCTGTATGACTTTGCTAAGGAAAATATAATGG
AAGATGATGAGGGAGAAGTTGTGGAATACGTGGATGACCTCTTAGAACTGGAGGAGACCAGCTA
GCCCACAGCAACCAAAGAGACTTCCTCTTGACGTTCAGGAAACACAGATTCTTCGTCCTTTTGC
CAACAGCCCAGGCTGTTGATACCTCAGAGCCTTCCCTTTACTCTCCGAAGTGAAAGGGAAGCCC
CCATCTCTCTCACTACATGTCACCAGGGGTGAGCCTGCCTTTCCCGTCTTCACACCTGCCACCT
CGTGTTCACACCTATCTTTCTTACCTTCTTTTTGAGATGGAGTCTCGCTCTGTCGCCCAGGCTG
GAGTCCTTTGGCACGTTCTCGGCTCAC

hide sequence

Protein Sequences


Protein RefSeqs	XP_008007581	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000005672.1

RefSeq Acc Id:	XP_008007581 ⟸ XM_008009390
- UniProtKB:	A0A0D9RAN3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000005672 ⟸ ENSCSAT00000007495

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000009478	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000007495.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
InterPro	Collagen_mod_leprecan	UniProtKB/TrEMBL
	TPR-like_helical_dom_sf	UniProtKB/TrEMBL
NCBI Gene	CRTAP	ENTREZGENE
PANTHER	PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT	UniProtKB/TrEMBL
	PTHR13986:SF3	UniProtKB/TrEMBL
UniProt	A0A0D9RAN3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-09	CRTAP	cartilage associated protein	LOC103241841	cartilage associated protein	Symbol and/or name change	5135510	APPROVED
2020-12-08	LOC103241841	cartilage associated protein	CRTAP	cartilage associated protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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