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Gene: CISD3 (CDGSH iron sulfur domain 3) Chlorocebus sabaeus

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Symbol:

CISD3

Name:

CDGSH iron sulfur domain 3

RGD ID:

18392290

Description:

ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN protein maturation (inferred); ASSOCIATED WITH genetic disease (ortholog); Turnpenny-Fry Syndrome (ortholog); Wolfram syndrome 2 (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

CDGSH iron-sulfur domain-containing protein 3, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	67,462,038 - 67,465,843 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	67,458,472 - 67,465,572 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	38,459,661 - 38,463,171 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CISD3	Green Monkey	genetic disease		ISO	RGD:1626692	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:28492532\|PMID:36413997
CISD3	Green Monkey	Turnpenny-Fry Syndrome		ISO	RGD:1626692	8554872	ClinVar Annotator: match by term: PCGF2-related condition \| ClinVar Annotator: match by term: Turnpenny-fry syndrome	ClinVar	PMID:25741868\|PMID:28492532
CISD3	Green Monkey	Wolfram syndrome 2		ISO	RGD:1626692	8554872	ClinVar Annotator: match by term: Wolfram syndrome 2	ClinVar	PMID:25741868

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CISD3	Green Monkey	protein maturation	involved_in	IEA	UniProtKB:P0C7P0\|ensembl:ENSP00000483781	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CISD3	Green Monkey	cytoplasm	located_in	IEA	ARBA:ARBA00026971	150520179		UniProt	GO_REF:0000117
CISD3	Green Monkey	mitochondrion	located_in	IEA	PANTHER:PTN002925593	150520179		TreeGrafter	GO_REF:0000118
CISD3	Green Monkey	mitochondrion	located_in	IEA	UniProtKB:P0C7P0\|ensembl:ENSP00000483781	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CISD3	Green Monkey	2 iron, 2 sulfur cluster binding	enables	IEA	PANTHER:PTN002925593	150520179		TreeGrafter	GO_REF:0000118
CISD3	Green Monkey	2 iron, 2 sulfur cluster binding	enables	IEA	UniProtKB-KW:KW-0001	150520179		UniProt	GO_REF:0000043
CISD3	Green Monkey	2 iron, 2 sulfur cluster binding	enables	IEA	InterPro:IPR018967	150520179		InterPro	GO_REF:0000002
CISD3	Green Monkey	2 iron, 2 sulfur cluster binding	enables	IEA	UniProtKB:P0C7P0\|ensembl:ENSP00000483781	150520179		Ensembl	GO_REF:0000107
CISD3	Green Monkey	iron-sulfur cluster binding	enables	IEA	UniProtKB-KW:KW-0411	150520179		UniProt	GO_REF:0000043
CISD3	Green Monkey	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
CISD3	Green Monkey	metal ion binding	enables	IEA	UniProtKB:P0C7P0\|ensembl:ENSP00000483781	150520179		Ensembl	GO_REF:0000107

PMID:22301074

CISD3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	67,462,038 - 67,465,843 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	67,458,472 - 67,465,572 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	38,459,661 - 38,463,171 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CISD3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	38,730,341 - 38,735,605 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	38,730,341 - 38,735,605 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	36,886,594 - 36,891,858 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	34,138,986 - 34,145,383 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	33,547,468 - 33,552,818 (+)	NCBI		Celera
Cytogenetic Map	17	q12	NCBI
HuRef	17	32,683,132 - 32,687,987 (+)	NCBI		HuRef
CHM1_1	17	37,121,826 - 37,127,177 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	39,593,426 - 39,598,690 (+)	NCBI		T2T-CHM13v2.0

Cisd3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	97,576,291 - 97,579,451 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	97,576,652 - 97,579,447 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	97,685,465 - 97,688,625 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	97,685,826 - 97,688,621 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	97,547,266 - 97,549,939 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	97,501,677 - 97,504,715 (+)	NCBI		MGSCv36	mm8
Celera	11	107,335,758 - 107,338,441 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	61.06	NCBI

Cisd3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	83,175,708 - 83,178,739 (+)	NCBI		GRCr8
mRatBN7.2	10	82,679,345 - 82,682,376 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	82,679,196 - 82,682,550 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	87,627,099 - 87,630,127 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	87,125,190 - 87,128,218 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	82,517,771 - 82,520,799 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	85,628,579 - 85,631,656 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	85,628,491 - 85,631,657 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	85,415,946 - 85,419,003 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	86,434,901 - 86,437,932 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	81,435,130 - 81,438,161 (+)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

Cisd3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	13,814,135 - 13,817,334 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	13,814,679 - 13,817,334 (+)	NCBI	ChiLan1.0	ChiLan1.0

CISD3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	26,216,912 - 26,220,675 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	28,100,485 - 28,103,892 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	18,538,545 - 18,543,374 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	18,815,044 - 18,820,685 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	18,815,044 - 18,817,980 (-)	Ensembl	panpan1.1		panPan2

CISD3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	23,501,167 - 23,504,302 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	23,501,168 - 23,504,308 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1

Cisd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	22,936,199 - 22,938,976 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	14,136,640 - 14,138,969 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	14,136,209 - 14,138,940 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CISD3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	23,376,002 - 23,379,584 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	23,375,998 - 23,379,587 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Cisd3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	3,952,477 - 3,955,127 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	3,952,500 - 3,955,123 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in CISD3
69 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20


RefSeq Transcripts	XM_008012905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008012907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008012908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008012909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000000660 ⟹ ENSCSAP00000015403

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	67,458,472 - 67,465,572 (-)	Ensembl

RefSeq Acc Id:

XM_008012905 ⟹ XP_008011096

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	67,462,038 - 67,465,843 (-)	NCBI
Vero_WHO_p1.0	NW_023666077	38,459,661 - 38,463,171 (-)	NCBI

Sequence:

show sequence

CAGGGTGCATCAATCCGTGGGCACCGGCCGTCGGGACCCTGACCCGTCCCGAGGTGACGCGACGCCCGCGTACTCGCTCCCAGAAGCGCGGCTGAGGCTCGGCCAGCAACAGTGAATCCTGGGAAGGT
CCCGTGCCCTCGCGGGTGCCCCAGACGCTGAGGCTGTGCGCGGGGCGTTCCGCCGCCAGACCCGCCCGGCAGGGGGCGCCAGGGCCGACCGCTCACGCCCGGCGCGCCGAGGAGGCCGCTGGGCGGGC
CCCGCGGCCAGGCTTCCGGACCCCGTCGGCCCCTGGCCTTAGCCCTCGCAGAACGCTGCGGCGTCTTCCGGGGCCTGGCGGGCCGGGGACCGAGGGGGCGGGGAGGTGACCCGGCCGGGGCGGAGCCG
GCGCGGGCGGGGGCACAGGCGCGGCCAGAAGGCGGCCATGCGCTGCGTGGGGGCGATCTTGCGGCCGGCGGCGCACGGCGCCTGGGACCTGAACCCGCGGCGGGACATCTCCTCCTGGCTGGCCCGGT
GGTTCCCTAGAACCCCAGCCAGGTCTGTGGTGGCCCTGAAGACCCCCATCAAAGTGGAGCTGGTGGCAGGGAAAACCTACAGGTGGTGTGTGTGTGGCCGCAGCAAGAAGCAGGTGAGACACCTACCT
GCCTTCCTACTGATACCTCCATCTGGGAATAGCCTGGTGTCTCCACCCTTCTGTGACGGCTCCCACTTCTTCCAACGCACTGGCCTATCTCCCCTCAAGTTCAAGGCCCAAGAGACCCGCACGGTGGC
ACTCTGTACCTGCAAGGCCACTCAGAGGCCCCCGTACTGCGATGGCACCCACAGGAGTGAGCGCGTGCAGAAGGCAGAAGTGGGCTCCCCACTCTGAGGGGGCTGCTGCTGTCCAGCCACAGGTGGCC
TTGGCTCCTGGCCTCTGACAGGCACCCCCTTCTGTGGGAAAGGAAACAGGTGCTGAGCCCAAGAAAGAGATTGTGGTACCCACAGCTGGCTCATGAAGGAAGAATTCTTCCCTATAACCTAAAAGTCT
CCAGTCTGGGGCAGGCGGGAGTGGGCCCTGGTTCAATGTTTGCTGATGGGGAAGATGGCAAAAACAAGCCGCCCAACTAGA

hide sequence

RefSeq Acc Id:

XM_008012908 ⟹ XP_008011099

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	67,462,038 - 67,465,666 (-)	NCBI
Vero_WHO_p1.0	NW_023666077	38,459,661 - 38,463,171 (-)	NCBI

Sequence:

show sequence

CCGCCGCCAGACCCGCCCGGCAGGGGGCGCCAGGGCCGACCGCTCACGCCCGGCGCGCCGAGGAGGCCGCTGGGCGGGCCCCGCGGCCAGGCTTCCGGACCCCGTCGGCCCCTGGCCTTAGCCCTCGC
AGAACGCTGCGGCGTCTTCCGGGGCCTGGCGGGCCGGGGACCGAGGGGGCGGGGAGGTGACCCGGCCGGGGCGGAGCCGGCGCGGGCGGGGGCACAGGCGCGGCCAGAAGGCGGCCATGCGCTGCGTG
GGGGCGATCTTGCGGCCGGCGGCGCACGGCGCCTGGGACCTGAACCCGCGGCGGGACATCTCCTCCTGGCTGGCCCGGTGGTTCCCTAGAACCCCAGCCAGGTCTGTGGTGGCCCTGAAGACCCCCAT
CAAAGTGGAGCTGGTGGCAGGGAAAACCTACAGGTGGTGTGTGTGTGGCCGCAGCAAGAAGCAGCCCTTCTGTGACGGCTCCCACTTCTTCCAACGCACTGGCCTATCTCCCCTCAAGTTCAAGGCCC
AAGAGACCCGCACGGTGGCACTCTGTACCTGCAAGGCCACTCAGAGGCCCCCGTACTGCGATGGCACCCACAGGAGTGAGCGCGTGCAGAAGGCAGAAGTGGGCTCCCCACTCTGAGGGGGCTGCTGC
TGTCCAGCCACAGGTGGCCTTGGCTCCTGGCCTCTGACAGGCACCCCCTTCTGTGGGAAAGGAAACAGGTGCTGAGCCCAAGAAAGAGATTGTGGTACCCACAGCTGGCTCATGAAGGAAGAATTCTT
CCCTATAACCTAAAAGTCTCCAGTCTGGGGCAGGCGGGAGTGGGCCCTGGTTCAATGTTTGCTGATGGGGAAGATGGCAAAAACAAGCCGCCCAACTAGA

hide sequence


Protein RefSeqs	XP_008011096	(Get FASTA)	NCBI Sequence Viewer
	XP_008011099	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000015403
	ENSCSAP00000015403.1

RefSeq Acc Id:	XP_008011096 ⟸ XM_008012905
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_008011099 ⟸ XM_008012908
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9S3G4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000015403 ⟸ ENSCSAT00000000660

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000002644	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000000660.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.5.90	UniProtKB/TrEMBL
InterPro	CISD	UniProtKB/TrEMBL
	FeS-contain_CDGSH-typ	UniProtKB/TrEMBL
	FeS-contain_mitoNEET_C	UniProtKB/TrEMBL
NCBI Gene	CISD3	ENTREZGENE
PANTHER	CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG	UniProtKB/TrEMBL
	CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	zf-CDGSH	UniProtKB/TrEMBL
SMART	ZnF_CDGSH	UniProtKB/TrEMBL
UniProt	A0A0D9S3G4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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