LOC128927767 (STARR-seq mESC enhancer starr_43693) - Rat Genome Database

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Gene: LOC128927767 (STARR-seq mESC enhancer starr_43693) Mus musculus
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Symbol: LOC128927767
Name: STARR-seq mESC enhancer starr_43693
RGD ID: 163650607
Description: This genomic region represents an enhancer that was validated by the STARR-seq (self-transcribing active regulatory region sequencing) reporter assay in metastable (SL) mouse embryonic stem cells, where it was defined as a C1 class enhancer that overlaps an active chromatin signature. This locus also includes a candidate cis-regulatory module (CRM) that was identified in developing mouse thymocytes based on a combination of DNase I hypersensitivity and transcription factor binding. That CRM was validated as an active enhancer by high-throughput CapStarr-seq reporter assays showing weak activity in P5424 T cells and NIH3T3 fibroblasts. [provided by RefSeq, Jul 2023]
Type: biological-region
RefSeq Status: REVIEWED
Previously known as: CapStarr-seq enhancer MGSCv37_chr18:5162506-5162663; Rr370336
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39185,162,110 - 5,164,771 (+)NCBIGRCm39GRCm39mm39
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:25872643   PMID:32912294  


Genomics

Variants

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Variants in LOC128927767
68 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142127Rafaril_mRafar interacting locus (mouse)Not determined18123108555Mouse
14928307Manh83_mmandible shape 83 (mouse)18126902168Mouse
12801458Intmrm3_mintima/media ratio modifier 3 (mouse)18131720756Mouse
11354953Mom21_mmodifier of Min 21 (mouse)18128893823Mouse
12801462Intim3_mintima modifier 3 (mouse)18131720756Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961272643Mouse
13207585Mwmlpt3_mMorris water maze latency to platform, training, 3 (mouse)18133547739Mouse
13207589Mwmlpa3_mMorris water maze latency to platform, all, 3 (mouse)18133547739Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060933072Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_153378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information

Database Acc Id Source(s)
NCBI Gene LOC128927767 ENTREZGENE
PhenoGen LOC128927767 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-25 LOC128927767  STARR-seq mESC enhancer starr_43693  LOC128927767  CapStarr-seq enhancer MGSCv37_chr18:5162506-5162663  Symbol and/or name change 5135510 APPROVED