LOC128925342 (STARR-positive B cell enhancer ABC_E1311) - Rat Genome Database

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Gene: LOC128925342 (STARR-positive B cell enhancer ABC_E1311) Mus musculus
Analyze
Symbol: LOC128925342
Name: STARR-positive B cell enhancer ABC_E1311
RGD ID: 163650068
Description: This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. A subregion was identified as a candidate cis-regulatory module (CRM) in developing mouse thymocytes based on a combination of DNase I hypersensitivity and transcription factor binding. That CRM was validated as an active enhancer by high-throughput CapStarr-seq reporter assays showing weak activity in NIH3T3 fibroblasts. [provided by RefSeq, Oct 2023]
Type: biological-region
RefSeq Status: REVIEWED
Previously known as: CapStarr-seq enhancer MGSCv37_chr5:136438367-136438476; Rr367968
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,991,251 - 135,991,552 (+)NCBIGRCm39GRCm39mm39
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:25872643   PMID:31873292   PMID:31873293  


Genomics

Variants

.
Variants in LOC128925342
13 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
13464143Bbaa2b_mB.burgdorferi-associated arthritis 2b (mouse)5133052969140709801Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5133925558151758149Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
14700793Mencq4_mmeniscus calcification QTL 4 (mouse)5135895854136218854Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_151040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC087420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information

Database Acc Id Source(s)
NCBI Gene LOC128925342 ENTREZGENE
PhenoGen LOC128925342 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-10 LOC128925342  STARR-positive B cell enhancer ABC_E1311  LOC128925342  CapStarr-seq enhancer MGSCv37_chr5:136438367-136438476  Symbol and/or name change 5135510 APPROVED