Snx9 (sorting nexin 9) - Rat Genome Database

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Gene: Snx9 (sorting nexin 9) Mus musculus
Analyze
Symbol: Snx9
Name: sorting nexin 9
RGD ID: 1621547
MGI Page MGI
Description: Enables phosphatidylinositol binding activity. Involved in positive regulation of actin filament polymerization. Acts upstream of or within intracellular protein transport. Located in cytoplasm and plasma membrane. Colocalizes with cuticular plate. Is expressed in lower jaw molar and upper jaw molar. Orthologous to human SNX9 (sorting nexin 9).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2700073N08Rik; SD; SDP1; SH3P; SH3PX1; sorting nexin-9; sorting nexin-9-like
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,891,599 - 5,982,231 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,891,604 - 5,982,229 (+)EnsemblGRCm39 Ensembl
GRCm38175,841,324 - 5,931,956 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,841,329 - 5,931,954 (+)EnsemblGRCm38mm10GRCm38
MGSCv37175,841,380 - 5,930,711 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36175,797,862 - 5,887,193 (+)NCBIMGSCv36mm8
Celera176,430,109 - 6,474,633 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map173.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12917015   PMID:14610273   PMID:15489334  
PMID:15722415   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693   PMID:21267068   PMID:21873635   PMID:23437151   PMID:25107275   PMID:27034005   PMID:27655699  
PMID:32325033   PMID:32554809   PMID:35449600   PMID:37839992  


Genomics

Comparative Map Data
Snx9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,891,599 - 5,982,231 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,891,604 - 5,982,229 (+)EnsemblGRCm39 Ensembl
GRCm38175,841,324 - 5,931,956 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,841,329 - 5,931,954 (+)EnsemblGRCm38mm10GRCm38
MGSCv37175,841,380 - 5,930,711 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36175,797,862 - 5,887,193 (+)NCBIMGSCv36mm8
Celera176,430,109 - 6,474,633 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map173.51NCBI
SNX9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386157,823,246 - 157,945,077 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6157,700,387 - 157,945,077 (+)EnsemblGRCh38hg38GRCh38
GRCh376158,244,278 - 158,366,109 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366158,164,282 - 158,286,097 (+)NCBINCBI36Build 36hg18NCBI36
Build 346158,214,702 - 158,336,518NCBI
Celera6158,893,214 - 159,014,998 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6155,760,951 - 155,838,449 (+)NCBIHuRef
CHM1_16158,506,443 - 158,628,331 (+)NCBICHM1_1
T2T-CHM13v2.06159,069,178 - 159,191,298 (+)NCBIT2T-CHM13v2.0
Snx9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8148,827,061 - 48,915,215 (+)NCBIGRCr8
mRatBN7.2146,424,897 - 46,510,096 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,423,553 - 46,509,036 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx146,975,856 - 47,059,358 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0152,963,109 - 53,046,607 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,051,280 - 47,134,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0146,780,142 - 46,826,250 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl146,779,860 - 46,825,830 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,084,891 - 48,130,894 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera142,155,821 - 42,201,820 (+)NCBICelera
Cytogenetic Map1q11NCBI
Snx9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554394,421,297 - 4,503,393 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554394,422,385 - 4,503,408 (-)NCBIChiLan1.0ChiLan1.0
SNX9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25177,840,146 - 178,058,536 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16175,841,464 - 175,961,940 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06155,724,026 - 155,844,553 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16157,826,651 - 157,903,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6157,824,918 - 157,903,357 (+)Ensemblpanpan1.1panPan2
SNX9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,346,214 - 47,457,417 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,343,668 - 47,455,937 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha148,191,531 - 48,302,806 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,532,216 - 47,644,795 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl147,530,968 - 47,644,779 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,412,288 - 47,523,565 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,282,028 - 47,393,272 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0147,840,744 - 47,952,026 (+)NCBIUU_Cfam_GSD_1.0
Snx9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946142,484,264 - 142,552,848 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364899,736,242 - 9,804,874 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364899,736,255 - 9,804,841 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl19,130,338 - 9,239,029 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.119,130,360 - 9,239,023 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2111,253,605 - 11,362,628 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNX9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11385,468,837 - 85,549,351 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1385,468,479 - 85,549,988 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604057,787,751 - 57,911,509 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624785282,512 - 374,378 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624785283,886 - 374,740 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Snx9
3069 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:474
Count of miRNA genes:300
Interacting mature miRNAs:320
Transcripts:ENSMUST00000002436
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120975022Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120975022Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_025664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC168063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000002436   ⟹   ENSMUSP00000002436
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl175,891,604 - 5,982,229 (+)Ensembl
GRCm38.p6 Ensembl175,841,329 - 5,931,954 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231803
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl175,891,627 - 5,940,405 (+)Ensembl
GRCm38.p6 Ensembl175,841,352 - 5,890,130 (+)Ensembl
RefSeq Acc Id: NM_025664   ⟹   NP_079940
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39175,891,599 - 5,982,231 (+)NCBI
GRCm38175,841,324 - 5,931,956 (+)NCBI
MGSCv37175,841,380 - 5,930,711 (+)RGD
Celera176,430,120 - 6,474,633 (+)ENTREZGENE
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017317612   ⟹   XP_017173101
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39175,916,274 - 5,981,318 (+)NCBI
GRCm38175,865,988 - 5,931,162 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249990   ⟹   XP_030105850
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39175,949,423 - 5,981,318 (+)NCBI
GRCm38175,899,146 - 5,931,162 (+)NCBI
Sequence:
RefSeq Acc Id: NP_079940   ⟸   NM_025664
- UniProtKB: Q91VH2 (UniProtKB/Swiss-Prot),   Q3U1P2 (UniProtKB/TrEMBL),   Q3TZU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173101   ⟸   XM_017317612
- Peptide Label: isoform X1
- UniProtKB: Q3TZU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030105850   ⟸   XM_030249990
- Peptide Label: isoform X2
- UniProtKB: Q9CZK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000002436   ⟸   ENSMUST00000002436
Protein Domains
BAR   PX   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91VH2-F1-model_v2 AlphaFold Q91VH2 1-595 view protein structure

Promoters
RGD ID:6828705
Promoter ID:MM_KWN:21947
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   Spleen
Transcripts:NM_025664
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36175,841,076 - 5,841,827 (+)MPROMDB
RGD ID:13674626
Promoter ID:EPDNEW_M21463
Type:initiation region
Name:Snx9_1
Description:Mus musculus sorting nexin 9 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38175,841,365 - 5,841,425EPDNEW
RGD ID:6828704
Promoter ID:MM_KWN:21949
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney
Transcripts:ENSMUST00000002436
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36175,886,726 - 5,887,226 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913866 AgrOrtholog
Ensembl Genes ENSMUSG00000002365 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000002436 ENTREZGENE
  ENSMUST00000002436.11 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNX9_BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Snx9_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNX9_PX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNX9_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sorting_nexin_WASP-bd-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1913866 ENTREZGENE
NCBI Gene 66616 ENTREZGENE
PANTHER PTHR45827:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SORTING NEXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BAR_3_WASP_bdg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00787 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Snx9 PhenoGen
PIRSF Snx9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PS50195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF64268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q3TZU7 ENTREZGENE, UniProtKB/TrEMBL
  Q3U1P2 ENTREZGENE, UniProtKB/TrEMBL
  Q91VH2 ENTREZGENE
  Q9CZK0 ENTREZGENE, UniProtKB/TrEMBL
  SNX9_MOUSE UniProtKB/Swiss-Prot