Krtap21-1 (keratin associated protein 21-1) - Rat Genome Database

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Gene: Krtap21-1 (keratin associated protein 21-1) Mus musculus
Analyze
Symbol: Krtap21-1
Name: keratin associated protein 21-1
RGD ID: 1621384
MGI Page MGI
Description: Acts upstream of or within several processes, including hair follicle development; pigment accumulation in tissues; and post-embryonic camera-type eye development. Predicted to be located in intermediate filament.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110017B05Rik; AI506979; KAP21.1; keratin associated protein 16-7; keratin-associated protein 16-7; keratin-associated protein 16.7; keratin-associated protein 21-1; Krtap1; Krtap16-7
RGD Orthologs
Human
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391689,199,915 - 89,200,662 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1689,200,106 - 89,200,756 (-)EnsemblGRCm39 Ensembl
GRCm381689,403,027 - 89,403,774 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1689,403,218 - 89,403,868 (-)EnsemblGRCm38mm10GRCm38
MGSCv371689,403,272 - 89,404,019 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361689,403,272 - 89,404,049 (-)NCBIMGSCv36mm8
Celera1689,601,944 - 89,602,742 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1651.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11290294   PMID:12466851   PMID:12477932   PMID:15385554   PMID:16141072   PMID:16141073   PMID:17151017   PMID:18721477  
PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Krtap21-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391689,199,915 - 89,200,662 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1689,200,106 - 89,200,756 (-)EnsemblGRCm39 Ensembl
GRCm381689,403,027 - 89,403,774 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1689,403,218 - 89,403,868 (-)EnsemblGRCm38mm10GRCm38
MGSCv371689,403,272 - 89,404,019 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361689,403,272 - 89,404,049 (-)NCBIMGSCv36mm8
Celera1689,601,944 - 89,602,742 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1651.42NCBI
AL445238.1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381363,832,361 - 63,833,053 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1363,832,361 - 63,833,531 (-)EnsemblGRCh38hg38GRCh38
GRCh371364,406,494 - 64,407,186 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map13q21.31NCBI
CHM1_11364,288,497 - 64,288,977 (+)NCBICHM1_1
T2T-CHM13v2.01363,053,933 - 63,054,625 (-)NCBIT2T-CHM13v2.0
LOC111093530
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13125,744,080 - 25,745,146 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3125,734,817 - 25,735,818 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03125,859,202 - 25,860,233 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13125,806,714 - 25,807,715 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03125,818,314 - 25,819,315 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03126,286,598 - 26,287,623 (-)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Krtap21-1
42 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:119
Interacting mature miRNAs:126
Transcripts:ENSMUST00000078422
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166860072298008968Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163544664392573008Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166332733697327472Mouse
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6298664696986646Mouse
1301364Lith14_mlithogenic gene 14 (mouse)Not determined165566184689661961Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166912761198008968Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166912761198008968Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167038025298008968Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166912761198008968Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166925448298008968Mouse
1300928Etia_methanol induced activation (mouse)Not determined166331390797314016Mouse
1301125Sluc27_msusceptibility to lung cancer 27 (mouse)Not determined166160864495608764Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166907613298008968Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000078422   ⟹   ENSMUSP00000077524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1689,200,106 - 89,200,756 (-)Ensembl
GRCm38.p6 Ensembl1689,403,218 - 89,403,868 (-)Ensembl
RefSeq Acc Id: NM_028621   ⟹   NP_082897
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391689,199,915 - 89,200,662 (-)NCBI
GRCm381689,403,027 - 89,403,774 (-)ENTREZGENE
MGSCv371689,403,272 - 89,404,019 (-)RGD
Celera1689,601,944 - 89,602,742 (-)RGD
cM Map16 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_082897 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI47777 (Get FASTA)   NCBI Sequence Viewer  
  AAI47787 (Get FASTA)   NCBI Sequence Viewer  
  AAK52895 (Get FASTA)   NCBI Sequence Viewer  
  BAB22970 (Get FASTA)   NCBI Sequence Viewer  
  EDK98379 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000077524
  ENSMUSP00000077524.3
GenBank Protein Q925H4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_082897   ⟸   NM_028621
- UniProtKB: B9EK12 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000077524   ⟸   ENSMUST00000078422

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q925H4-F1-model_v2 AlphaFold Q925H4 1-128 view protein structure

Promoters
RGD ID:13674374
Promoter ID:EPDNEW_M21336
Type:single initiation site
Name:Krtap21-1_1
Description:Mus musculus keratin associated protein 21-1 (Krtap21-1), mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381689,403,804 - 89,403,864EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000058368 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078422 ENTREZGENE
  ENSMUST00000078422.4 UniProtKB/TrEMBL
KEGG Report mmu:170656 UniProtKB/TrEMBL
MGD MGI:2157767 ENTREZGENE
NCBI Gene 170656 ENTREZGENE
PANTHER KERATIN-ASSOCIATED PROTEIN 21-1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR31294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Krtap21-1 PhenoGen
UniProt B9EK12 ENTREZGENE, UniProtKB/TrEMBL
  KR211_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q9D1B6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-21 Krtap21-1  keratin associated protein 21-1  Krtap21-1  keratin associated protein 21-1  Data merged from RGD:1616732 737654 PROVISIONAL
2012-07-31 Krtap21-1  keratin associated protein 21-1  Krtap16-7  keratin associated protein 16-7  Symbol and/or name change 5135510 APPROVED