Ccdc188 (coiled-coil domain containing 188) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ccdc188 (coiled-coil domain containing 188) Mus musculus
Analyze
Symbol: Ccdc188
Name: coiled-coil domain containing 188
RGD ID: 1621006
MGI Page MGI
Description: Is expressed in nervous system and neural retina. Orthologous to human CCDC188 (coiled-coil domain containing 188).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: coiled-coil domain-containing protein 188; EG665975; Gm7873; predicted gene, EG665975
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,032,091 - 18,038,211 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,035,743 - 18,038,212 (+)EnsemblGRCm39 Ensembl
GRCm381618,214,227 - 18,220,347 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,217,879 - 18,220,348 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,217,972 - 18,220,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,131,026 - 18,133,910 (+)NCBIMGSCv36mm8
Celera1618,790,625 - 18,793,093 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21267068  


Genomics

Comparative Map Data
Ccdc188
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,032,091 - 18,038,211 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,035,743 - 18,038,212 (+)EnsemblGRCm39 Ensembl
GRCm381618,214,227 - 18,220,347 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,217,879 - 18,220,348 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,217,972 - 18,220,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,131,026 - 18,133,910 (+)NCBIMGSCv36mm8
Celera1618,790,625 - 18,793,093 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.29NCBI
CCDC188
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,148,416 - 20,151,055 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,148,416 - 20,151,055 (-)EnsemblGRCh38hg38GRCh38
GRCh372220,135,939 - 20,138,578 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,515,950 - 18,531,131 (-)NCBINCBI36Build 36hg18NCBI36
Celera223,988,159 - 3,989,475 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef223,756,722 - 3,758,044 (-)NCBIHuRef
CHM1_12220,135,800 - 20,137,122 (-)NCBICHM1_1
T2T-CHM13v2.02220,527,451 - 20,534,406 (-)NCBIT2T-CHM13v2.0
Ccdc188
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,273,615 - 96,276,496 (-)NCBIGRCr8
mRatBN7.21182,769,735 - 82,772,062 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,769,473 - 82,772,114 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01186,917,349 - 86,920,091 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,917,667 - 86,920,094 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,011,605 - 90,014,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1181,546,278 - 81,549,021 (-)NCBICelera
Cytogenetic Map11q23NCBI
Ccdc188
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544217,962,249 - 17,965,261 (+)NCBIChiLan1.0ChiLan1.0
CCDC188
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,775,452 - 29,778,774 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12232,322,329 - 32,329,851 (-)NCBINHGRI_mPanPan1
PanPan1.12218,580,908 - 18,585,074 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2218,582,301 - 18,585,074 (-)Ensemblpanpan1.1panPan2
CCDC188
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,189,736 - 29,194,606 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,189,880 - 29,192,286 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,148,736 - 29,153,598 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02630,593,855 - 30,598,718 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,593,995 - 30,597,011 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,641,702 - 28,646,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,267,066 - 28,271,929 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,352,051 - 29,356,910 (+)NCBIUU_Cfam_GSD_1.0
Ccdc188
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118138,702,990 - 138,707,429 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366194,048,686 - 4,049,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC188
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,517,234 - 51,520,622 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,517,669 - 51,520,622 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21455,155,083 - 55,157,538 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC188
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,589,399 - 5,592,135 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660851,343,097 - 1,346,005 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc188
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624747756,298 - 759,056 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:176
Count of miRNA genes:161
Interacting mature miRNAs:175
Transcripts:ENSMUST00000167061
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
15092082Igly9_mIgG glycosylation 9, GP17b (mouse)161477522320103513Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001370887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_169085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_384716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_875941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC006082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC012526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC118542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000167061   ⟹   ENSMUSP00000132278
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1618,036,034 - 18,037,177 (+)Ensembl
GRCm38.p6 Ensembl1618,218,170 - 18,219,313 (+)Ensembl
Ensembl Acc Id: ENSMUST00000231369   ⟹   ENSMUSP00000155981
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1618,035,743 - 18,038,209 (+)Ensembl
GRCm38.p6 Ensembl1618,217,879 - 18,220,345 (+)Ensembl
Ensembl Acc Id: ENSMUST00000231860   ⟹   ENSMUSP00000156197
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1618,035,743 - 18,038,205 (+)Ensembl
GRCm38.p6 Ensembl1618,217,879 - 18,220,341 (+)Ensembl
Ensembl Acc Id: ENSMUST00000231965   ⟹   ENSMUSP00000156029
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1618,035,743 - 18,038,212 (+)Ensembl
GRCm38.p6 Ensembl1618,217,879 - 18,220,348 (+)Ensembl
RefSeq Acc Id: NM_001370887   ⟹   NP_001357816
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,743 - 18,038,210 (+)NCBI
Sequence:
RefSeq Acc Id: NR_169085
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,743 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522809   ⟹   XP_006522872
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,514 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522811   ⟹   XP_006522874
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,514 - 18,038,209 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011246064   ⟹   XP_011244366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,514 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011246065   ⟹   XP_011244367
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,514 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011246066   ⟹   XP_011244368
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,878 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011246068   ⟹   XP_011244370
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,032,091 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017317179   ⟹   XP_017172668
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,514 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248901   ⟹   XP_030104761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,738 - 18,038,211 (+)NCBI
Sequence:
RefSeq Acc Id: XR_384716
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,514 - 18,037,916 (+)NCBI
Sequence:
RefSeq Acc Id: XR_875941
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391618,035,514 - 18,037,889 (+)NCBI
Sequence:
Ensembl Acc Id: ENSMUSP00000156029   ⟸   ENSMUST00000231965
Ensembl Acc Id: ENSMUSP00000156197   ⟸   ENSMUST00000231860
Ensembl Acc Id: ENSMUSP00000155981   ⟸   ENSMUST00000231369
Ensembl Acc Id: ENSMUSP00000132278   ⟸   ENSMUST00000167061
RefSeq Acc Id: XP_011244370   ⟸   XM_011246068
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006522872   ⟸   XM_006522809
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011244366   ⟸   XM_011246064
- Peptide Label: isoform X2
- UniProtKB: A0A338P6G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244367   ⟸   XM_011246065
- Peptide Label: isoform X4
- UniProtKB: A0A338P6G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172668   ⟸   XM_017317179
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006522874   ⟸   XM_006522811
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_030104761   ⟸   XM_030248901
- Peptide Label: isoform X7
RefSeq Acc Id: NP_001357816   ⟸   NM_001370887
- UniProtKB: A0A338P6G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_011244368   ⟸   XM_011246066
- Peptide Label: isoform X6
- Sequence:

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A338P6G2-F1-model_v2 AlphaFold A0A338P6G2 1-436 view protein structure

Promoters
RGD ID:6827093
Promoter ID:MM_KWN:20360
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:XM_980665_GM7873
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361618,217,486 - 18,217,986 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3647803 AgrOrtholog
Ensembl Genes ENSMUSG00000090777 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000167061.2 UniProtKB/TrEMBL
  ENSMUST00000231369 ENTREZGENE
  ENSMUST00000231369.2 UniProtKB/TrEMBL
  ENSMUST00000231860.2 UniProtKB/TrEMBL
  ENSMUST00000231965 ENTREZGENE
  ENSMUST00000231965.2 UniProtKB/TrEMBL
InterPro SMCO2/5 UniProtKB/TrEMBL
MGD MGI:3647803 ENTREZGENE
NCBI Gene Ccdc188 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 188 UniProtKB/TrEMBL
  PTHR22422 UniProtKB/TrEMBL
PhenoGen Ccdc188 PhenoGen
UniProt A0A338P6G2 ENTREZGENE, UniProtKB/TrEMBL
  A0A338P6M1_MOUSE UniProtKB/TrEMBL
  A0A338P6Z0_MOUSE UniProtKB/TrEMBL
  F6WEU2_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Ccdc188  coiled-coil domain containing 188  Gm7873  predicted gene 7873  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 Gm7873  predicted gene 7873  Ccdc188  coiled-coil domain containing 188  Symbol and/or name change 5135510 APPROVED
2018-10-09 Ccdc188  coiled-coil domain containing 188  Gm7873  predicted gene 7873  Symbol and/or name change 5135510 APPROVED