Ccdc187 (coiled-coil domain containing 187) - Rat Genome Database

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Gene: Ccdc187 (coiled-coil domain containing 187) Mus musculus
Analyze
Symbol: Ccdc187
Name: coiled-coil domain containing 187
RGD ID: 1620454
MGI Page MGI
Description: Predicted to enable microtubule binding activity. Predicted to be involved in microtubule anchoring. Predicted to be located in centrosome. Is expressed in brain ventricle and choroid plexus and nose. Orthologous to human CCDC187 (coiled-coil domain containing 187).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4932418E24Rik; coiled-coil domain-containing protein 187; hypothetical protein LOC329366; RP23-297I16.4; uncharacterized protein LOC329366
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,161,659 - 26,184,569 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,133,481 - 26,184,569 (-)EnsemblGRCm39 Ensembl
GRCm38226,243,449 - 26,300,204 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,243,469 - 26,294,557 (-)EnsemblGRCm38mm10GRCm38
MGSCv37226,127,167 - 26,150,077 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,093,656 - 26,116,566 (-)NCBIMGSCv36mm8
Celera225,994,444 - 26,017,147 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21267068   PMID:32325033  


Genomics

Comparative Map Data
Ccdc187
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,161,659 - 26,184,569 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,133,481 - 26,184,569 (-)EnsemblGRCm39 Ensembl
GRCm38226,243,449 - 26,300,204 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,243,469 - 26,294,557 (-)EnsemblGRCm38mm10GRCm38
MGSCv37226,127,167 - 26,150,077 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,093,656 - 26,116,566 (-)NCBIMGSCv36mm8
Celera225,994,444 - 26,017,147 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.54NCBI
CCDC187
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,249,973 - 136,306,901 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,249,973 - 136,306,901 (-)EnsemblGRCh38hg38GRCh38
GRCh379139,141,819 - 139,166,855 (-)NCBIGRCh37GRCh37hg19GRCh37
Celera9109,692,458 - 109,715,154 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9108,637,299 - 108,659,975 (-)NCBIHuRef
T2T-CHM13v2.09148,479,614 - 148,536,390 (-)NCBIT2T-CHM13v2.0
Ccdc187
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,468,292 - 29,525,002 (-)NCBIGRCr8
mRatBN7.239,070,192 - 9,127,001 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,070,185 - 9,126,946 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.033,724,656 - 3,747,440 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl33,724,656 - 3,747,440 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,086,793 - 9,115,518 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,451,179 - 4,473,859 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera33,918,377 - 3,941,161 (-)NCBICelera
Cytogenetic Map3p13NCBI
Ccdc187
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555134,393,583 - 4,433,285 (+)NCBIChiLan1.0ChiLan1.0
CCDC187
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2113,081,575 - 3,132,538 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan193,083,910 - 3,134,294 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,326,280 - 107,377,510 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,335,875 - 136,357,822 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,307,297 - 136,357,568 (-)Ensemblpanpan1.1panPan2
CCDC187
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,165,109 - 49,202,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,161,034 - 49,202,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,415,597 - 48,453,413 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0950,041,718 - 50,079,542 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1948,822,167 - 48,859,992 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,116,498 - 49,154,318 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,164,614 - 49,201,838 (+)NCBIUU_Cfam_GSD_1.0
Ccdc187
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947201,845,740 - 201,910,473 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366691,462,154 - 1,528,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC187
(Sus scrofa - pig)		 No map positions available.
CCDC187
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,927,571 - 1,950,730 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660583,263,536 - 3,314,445 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc187
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247601,459,803 - 1,499,531 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ccdc187
1132 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:404
Count of miRNA genes:298
Interacting mature miRNAs:336
Transcripts:ENSMUST00000057224, ENSMUST00000155409
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552706Cia24_mcollagen induced arthritis QTL 24 (mouse)Not determined22467911533523172Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
8552705Cia25_mcollagen induced arthritis 25 (mouse)Not determined22467911533523172Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301838Sluc16_msusceptibility to lung cancer 16 (mouse)Not determined2126529589Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
12904743Carcdq3_mcardiac collagen deposition QTL 3 (mouse)2323494028179150Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
12903993Opfaq1_mopen field activity QTL 1 (mouse)2967669127022642Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000057224   ⟹   ENSMUSP00000054283
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,161,658 - 26,184,569 (-)Ensembl
GRCm38.p6 Ensembl226,271,646 - 26,294,557 (-)Ensembl
Ensembl Acc Id: ENSMUST00000217256   ⟹   ENSMUSP00000150719
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,133,481 - 26,184,450 (-)Ensembl
GRCm38.p6 Ensembl226,243,469 - 26,294,438 (-)Ensembl
Ensembl Acc Id: ENSMUST00000227200   ⟹   ENSMUSP00000153797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,133,481 - 26,184,450 (-)Ensembl
GRCm38.p6 Ensembl226,243,469 - 26,294,438 (-)Ensembl
RefSeq Acc Id: NM_177841   ⟹   NP_808509
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39226,161,659 - 26,184,569 (-)NCBI
GRCm38226,271,647 - 26,294,557 (-)NCBI
MGSCv37226,127,167 - 26,150,077 (-)RGD
Celera225,994,444 - 26,017,147 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_808509   ⟸   NM_177841
- UniProtKB: Q8C5V8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000150719   ⟸   ENSMUST00000217256
Ensembl Acc Id: ENSMUSP00000153797   ⟸   ENSMUST00000227200
Ensembl Acc Id: ENSMUSP00000054283   ⟸   ENSMUST00000057224

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C5V8-F1-model_v2 AlphaFold Q8C5V8 1-958 view protein structure

Promoters
RGD ID:6876682
Promoter ID:EPDNEW_M1792
Type:initiation region
Name:Ccdc187_1
Description:Mus musculus coiled-coil domain containing 187 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38226,294,608 - 26,294,668EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3045295 AgrOrtholog
Ensembl Genes ENSMUSG00000048038 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000057224 ENTREZGENE
  ENSMUST00000057224.4 UniProtKB/Swiss-Prot
  ENSMUST00000217256.2 UniProtKB/TrEMBL
  ENSMUST00000227200.2 UniProtKB/TrEMBL
InterPro CEP350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:329366 UniProtKB/Swiss-Prot
MGD MGI:3045295 ENTREZGENE
NCBI Gene 329366 ENTREZGENE
PANTHER CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  COILED-COIL DOMAIN-CONTAINING PROTEIN 187 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13958 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccdc187 PhenoGen
UniProt A0A1L1SUD9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2I3BPI0 ENTREZGENE, UniProtKB/TrEMBL
  CC187_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-17 Ccdc187  coiled-coil domain containing 187  4932418E24Rik  RIKEN cDNA 4932418E24 gene  Symbol and/or name change 5135510 APPROVED