Pja1 (praja ring finger ubiquitin ligase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Pja1 (praja ring finger ubiquitin ligase 1) Mus musculus
Analyze
Symbol: Pja1
Name: praja ring finger ubiquitin ligase 1
RGD ID: 1620099
MGI Page MGI
Description: Enables ubiquitin protein ligase activity. Acts upstream of or within protein catabolic process. Located in cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; ear; genitourinary system; and liver. Orthologous to human PJA1 (praja ring finger ubiquitin ligase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase Praja-1; E3 ubiquitin-protein ligase Praja1; praja ring finger 1, E3 ubiquitin protein ligase; praja-1; praja1, RING-H2 motif containing; RING-type E3 ubiquitin transferase Praja-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X98,509,344 - 98,514,874 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX98,509,340 - 98,514,879 (-)EnsemblGRCm39 Ensembl
GRCm38X99,465,734 - 99,471,268 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX99,465,734 - 99,471,273 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X96,661,073 - 96,666,074 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X95,668,865 - 95,673,391 (-)NCBIMGSCv36mm8
CeleraX86,405,285 - 86,410,248 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9393880   PMID:10198174   PMID:10349636   PMID:10500182   PMID:10722742   PMID:10922068   PMID:11042159   PMID:11044607   PMID:11076861   PMID:11217851   PMID:11438667  
PMID:11533224   PMID:11544199   PMID:11959851   PMID:12036302   PMID:12466851   PMID:12477932   PMID:14691545   PMID:15489334   PMID:15618518   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:18287559   PMID:21677750   PMID:21873635   PMID:22988430   PMID:23688634   PMID:28067271   PMID:31891772   PMID:32127355   PMID:32134507   PMID:32686212   PMID:35084365   PMID:36528254  
PMID:37196079   PMID:37712419   PMID:38355793  


Genomics

Comparative Map Data
Pja1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X98,509,344 - 98,514,874 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX98,509,340 - 98,514,879 (-)EnsemblGRCm39 Ensembl
GRCm38X99,465,734 - 99,471,268 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX99,465,734 - 99,471,273 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X96,661,073 - 96,666,074 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X95,668,865 - 95,673,391 (-)NCBIMGSCv36mm8
CeleraX86,405,285 - 86,410,248 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.38NCBI
PJA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X69,160,746 - 69,165,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX69,160,851 - 69,165,521 (-)EnsemblGRCh38hg38GRCh38
GRCh37X68,380,589 - 68,385,296 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X68,297,422 - 68,302,065 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X68,163,718 - 68,166,409NCBI
CeleraX68,733,493 - 68,738,277 (-)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX62,204,531 - 62,209,313 (-)NCBIHuRef
CHM1_1X68,273,990 - 68,278,774 (-)NCBICHM1_1
T2T-CHM13v2.0X67,594,126 - 67,598,833 (-)NCBIT2T-CHM13v2.0
Pja1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X68,621,101 - 68,626,001 (-)NCBIGRCr8
mRatBN7.2X64,580,938 - 64,585,846 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX64,580,849 - 64,585,833 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX66,064,443 - 66,069,292 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X69,564,800 - 69,569,649 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X67,125,694 - 67,130,543 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X69,213,645 - 69,218,601 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX69,213,645 - 69,218,556 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X70,086,011 - 70,090,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX64,945,766 - 64,948,345 (-)NCBICelera
Cytogenetic MapXq22NCBI
Pja1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554758,688,888 - 8,690,720 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554758,688,467 - 8,693,010 (-)NCBIChiLan1.0ChiLan1.0
PJA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X68,809,765 - 68,814,474 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X68,813,368 - 68,818,077 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X58,400,899 - 58,405,697 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X68,464,681 - 68,469,343 (-)NCBIpanpan1.1PanPan1.1panPan2
PJA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X53,608,459 - 53,614,270 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX44,435,116 - 44,439,770 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X54,575,157 - 54,579,816 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX54,574,010 - 54,579,774 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X52,543,076 - 52,547,730 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X53,871,826 - 53,876,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X53,795,660 - 53,800,314 (-)NCBIUU_Cfam_GSD_1.0
Pja1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X48,433,167 - 48,438,204 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936777796,756 - 798,726 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936777796,101 - 801,111 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PJA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX55,274,298 - 55,280,530 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X55,274,294 - 55,280,583 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X62,339,803 - 62,346,075 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PJA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X58,997,686 - 59,002,361 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX58,998,132 - 59,000,066 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666065855,813 - 860,490 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pja1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248911,085,068 - 1,086,903 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248911,082,774 - 1,087,338 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pja1
120 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1490
Count of miRNA genes:334
Interacting mature miRNAs:391
Transcripts:ENSMUST00000036354, ENSMUST00000113790, ENSMUST00000113792, ENSMUST00000113797, ENSMUST00000167246
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
4141803Lmr30_mleishmaniasis resistance 30 (mouse)Not determined85062606119062720Mouse
1302054Gct4_mgranulosa cell tumorigenesis 4 (mouse)Not determinedX76124336102062720Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
11075102Modc2_mmodifier of Odc2 (mouse)X80189914114190059Mouse
1357500Mdmsc6_mmodifier of muscularity 6 (mouse)Not determinedX75306671109306758Mouse
12879918Shm4_msperm head morphology 4 (mouse)X72072050102062720Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse

Markers in Region
U06944  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X99,466,234 - 99,466,368UniSTSGRCm38
MGSCv37X96,661,573 - 96,661,707UniSTSGRCm37
CeleraX86,405,786 - 86,405,920UniSTS
Cytogenetic MapXC3UniSTS
cM MapX36.6UniSTS
Whitehead/MRC_RHX1107.02UniSTS
RH137160  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X99,466,170 - 99,466,381UniSTSGRCm38
MGSCv37X96,661,509 - 96,661,720UniSTSGRCm37
CeleraX86,405,722 - 86,405,933UniSTS
Cytogenetic MapXC3UniSTS
cM MapX36.6UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001083110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF335250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF335251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF335252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL831752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD741074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN695027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000036354   ⟹   ENSMUSP00000109420
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX98,509,720 - 98,514,298 (-)Ensembl
GRCm38.p6 EnsemblX99,466,114 - 99,470,692 (-)Ensembl
Ensembl Acc Id: ENSMUST00000113790   ⟹   ENSMUSP00000109421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX98,509,344 - 98,514,293 (-)Ensembl
GRCm38.p6 EnsemblX99,465,738 - 99,470,687 (-)Ensembl
Ensembl Acc Id: ENSMUST00000113792   ⟹   ENSMUSP00000109423
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX98,509,340 - 98,514,879 (-)Ensembl
GRCm38.p6 EnsemblX99,465,734 - 99,471,273 (-)Ensembl
Ensembl Acc Id: ENSMUST00000113797   ⟹   ENSMUSP00000109428
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX98,509,752 - 98,514,278 (-)Ensembl
GRCm38.p6 EnsemblX99,466,146 - 99,470,672 (-)Ensembl
Ensembl Acc Id: ENSMUST00000167246   ⟹   ENSMUSP00000132393
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX98,509,374 - 98,514,341 (-)Ensembl
GRCm38.p6 EnsemblX99,465,768 - 99,470,735 (-)Ensembl
RefSeq Acc Id: NM_001083110   ⟹   NP_001076579
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,344 - 98,514,306 (-)NCBI
GRCm38X99,465,734 - 99,470,735 (-)NCBI
MGSCv37X96,661,073 - 96,666,074 (-)RGD
CeleraX86,405,285 - 86,410,248 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001290555   ⟹   NP_001277484
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,344 - 98,514,306 (-)NCBI
GRCm38X99,465,734 - 99,470,735 (-)NCBI
CeleraX86,405,285 - 86,410,248 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001290556   ⟹   NP_001277485
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,344 - 98,514,306 (-)NCBI
GRCm38X99,465,734 - 99,470,735 (-)NCBI
CeleraX86,405,285 - 86,410,248 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001425925   ⟹   NP_001412854
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,344 - 98,514,306 (-)NCBI
RefSeq Acc Id: NM_001425926   ⟹   NP_001412855
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,344 - 98,514,306 (-)NCBI
RefSeq Acc Id: NM_001425927   ⟹   NP_001412856
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,344 - 98,514,306 (-)NCBI
RefSeq Acc Id: NM_008853   ⟹   NP_032879
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,344 - 98,514,306 (-)NCBI
GRCm38X99,465,734 - 99,470,735 (-)NCBI
MGSCv37X96,661,073 - 96,666,074 (-)RGD
CeleraX86,405,285 - 86,410,248 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011247544   ⟹   XP_011245846
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X98,509,716 - 98,514,874 (-)NCBI
GRCm38X99,466,110 - 99,471,268 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001076579   ⟸   NM_001083110
- Peptide Label: isoform 1
- UniProtKB: Q99MJ3 (UniProtKB/Swiss-Prot),   Q99MJ2 (UniProtKB/Swiss-Prot),   Q99MJ1 (UniProtKB/Swiss-Prot),   Q8CFU2 (UniProtKB/Swiss-Prot),   Q9DB04 (UniProtKB/Swiss-Prot),   O55176 (UniProtKB/Swiss-Prot),   Q05CG5 (UniProtKB/TrEMBL),   Q3UXQ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_032879   ⟸   NM_008853
- Peptide Label: isoform 2
- UniProtKB: B1AXU3 (UniProtKB/TrEMBL),   A0JLS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277485   ⟸   NM_001290556
- Peptide Label: isoform 4
- UniProtKB: B1AXU4 (UniProtKB/TrEMBL),   A0JLS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277484   ⟸   NM_001290555
- Peptide Label: isoform 3
- UniProtKB: Q3UXQ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011245846   ⟸   XM_011247544
- Peptide Label: isoform X1
- UniProtKB: Q3UXQ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000109428   ⟸   ENSMUST00000113797
Ensembl Acc Id: ENSMUSP00000109421   ⟸   ENSMUST00000113790
Ensembl Acc Id: ENSMUSP00000109423   ⟸   ENSMUST00000113792
Ensembl Acc Id: ENSMUSP00000109420   ⟸   ENSMUST00000036354
Ensembl Acc Id: ENSMUSP00000132393   ⟸   ENSMUST00000167246
RefSeq Acc Id: NP_001412856   ⟸   NM_001425927
- Peptide Label: isoform 4
- UniProtKB: B1AXU4 (UniProtKB/TrEMBL),   A0JLS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001412854   ⟸   NM_001425925
- Peptide Label: isoform 1
- UniProtKB: Q9DB04 (UniProtKB/Swiss-Prot),   Q99MJ3 (UniProtKB/Swiss-Prot),   Q99MJ2 (UniProtKB/Swiss-Prot),   Q99MJ1 (UniProtKB/Swiss-Prot),   Q8CFU2 (UniProtKB/Swiss-Prot),   O55176 (UniProtKB/Swiss-Prot),   Q05CG5 (UniProtKB/TrEMBL),   Q3UXQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001412855   ⟸   NM_001425926
- Peptide Label: isoform 5
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O55176-F1-model_v2 AlphaFold O55176 1-578 view protein structure

Promoters
RGD ID:6846099
Promoter ID:MM_KWN:61256
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000113790,   ENSMUST00000113792,   NM_001083110,   NM_008853,   UC009TVM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X96,665,769 - 96,666,269 (-)MPROMDB
RGD ID:13681018
Promoter ID:EPDNEW_M24658
Type:initiation region
Name:Pja1_1
Description:Mus musculus praja ring finger ubiquitin ligase 1 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X99,470,688 - 99,470,748EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1101765 AgrOrtholog
Ensembl Genes ENSMUSG00000034403 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000036354 ENTREZGENE
  ENSMUST00000036354.7 UniProtKB/Swiss-Prot
  ENSMUST00000113790 ENTREZGENE
  ENSMUST00000113790.8 UniProtKB/TrEMBL
  ENSMUST00000113792 ENTREZGENE
  ENSMUST00000113792.2 UniProtKB/Swiss-Prot
  ENSMUST00000113797 ENTREZGENE
  ENSMUST00000113797.4 UniProtKB/TrEMBL
  ENSMUST00000167246 ENTREZGENE
  ENSMUST00000167246.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RING_finger_E3_ligase UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18744 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1101765 ENTREZGENE
NCBI Gene 18744 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE PRAJA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15710:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING ZINC FINGER-CONTAINING PROTEIN UniProtKB/TrEMBL
  SI:CH211-59O9.10 UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pja1 PhenoGen
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0JLS7 ENTREZGENE, UniProtKB/TrEMBL
  B1AXU3 ENTREZGENE, UniProtKB/TrEMBL
  B1AXU4 ENTREZGENE, UniProtKB/TrEMBL
  O55176 ENTREZGENE, UniProtKB/Swiss-Prot
  Q05CG5 ENTREZGENE, UniProtKB/TrEMBL
  Q3UXQ1 ENTREZGENE, UniProtKB/TrEMBL
  Q8CFU2 ENTREZGENE
  Q99MJ1 ENTREZGENE
  Q99MJ2 ENTREZGENE
  Q99MJ3 ENTREZGENE
  Q9DB04 ENTREZGENE
UniProt Secondary Q8CFU2 UniProtKB/Swiss-Prot
  Q99MJ1 UniProtKB/Swiss-Prot
  Q99MJ2 UniProtKB/Swiss-Prot
  Q99MJ3 UniProtKB/Swiss-Prot
  Q9DB04 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-20 Pja1  praja ring finger ubiquitin ligase 1    praja ring finger 1, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED
2014-06-10 Pja1  praja ring finger 1, E3 ubiquitin protein ligase    praja1, RING-H2 motif containing  Symbol and/or name change 5135510 APPROVED