Clec2g (C-type lectin domain family 2, member g) - Rat Genome Database

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Gene: Clec2g (C-type lectin domain family 2, member g) Mus musculus
Analyze
No known orthologs.
Symbol: Clec2g
Name: C-type lectin domain family 2, member g
RGD ID: 1619146
MGI Page MGI
Description: Enables natural killer cell lectin-like receptor binding activity. Acts upstream of or within negative regulation of osteoclast differentiation. Predicted to be located in cell surface and endoplasmic reticulum. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC2D (C-type lectin domain family 2 member D).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4632413B12Rik; C-type lectin domain family 2 member G; C-type lectin-related protein C; C-type lectin-related protein x variant 1; Clec2f; Clr-c; Clr-d; Clrc; Clrd; Clrx; Ddv10; MGC144756; Oc; ocil-related protein 1; Ocilrp1; osteoclast inhibitory lectin related protein; osteoclast inhibitory lectin-related protein 1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396128,911,344 - 128,961,670 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6128,911,344 - 128,961,670 (+)EnsemblGRCm39 Ensembl
GRCm386128,934,381 - 128,984,707 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6128,934,381 - 128,984,707 (+)EnsemblGRCm38mm10GRCm38
MGSCv376128,884,399 - 128,934,725 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366128,900,000 - 128,950,090 (+)NCBIMGSCv36mm8
Celera6130,636,744 - 130,692,143 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11398965   PMID:12374791   PMID:12466851   PMID:12477932   PMID:12746323   PMID:16141072   PMID:16141073   PMID:16460835  
PMID:16751398   PMID:19535641   PMID:20738764   PMID:21409442   PMID:21667046   PMID:21873635   PMID:25694214   PMID:26173808   PMID:32473917   PMID:38355793  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:989
Count of miRNA genes:446
Interacting mature miRNAs:499
Transcripts:ENSMUST00000000254, ENSMUST00000075789, ENSMUST00000142388, ENSMUST00000146925
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128601582149588044Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125333609134096586Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
4141151Ath38_matherosclerosis 38 (mouse)Not determined128495857136293176Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128601582149588044Mouse
10412215Cmv3_mcytomegalovirus resistance 3 (mouse)Not determined6128811857137416927Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128601582149588044Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
10412134Cmv4_mcytomegalovirus resistance 4 (mouse)Not determined6127815180136022150Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001168223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001168224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001316752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB091386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF320595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF320596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY137339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY137340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY137341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY137342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ143107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF431014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF792238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF792239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000000254   ⟹   ENSMUSP00000000254
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,911,344 - 128,961,667 (+)Ensembl
GRCm38.p6 Ensembl6128,934,381 - 128,984,704 (+)Ensembl
Ensembl Acc Id: ENSMUST00000075789   ⟹   ENSMUSP00000075192
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,956,372 - 128,960,155 (+)Ensembl
GRCm38.p6 Ensembl6128,979,409 - 128,983,192 (+)Ensembl
Ensembl Acc Id: ENSMUST00000142388   ⟹   ENSMUSP00000115140
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,948,123 - 128,961,670 (+)Ensembl
GRCm38.p6 Ensembl6128,971,160 - 128,984,707 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146925
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,911,368 - 128,925,948 (+)Ensembl
GRCm38.p6 Ensembl6128,934,405 - 128,948,985 (+)Ensembl
Ensembl Acc Id: ENSMUST00000203405   ⟹   ENSMUSP00000144788
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,948,123 - 128,960,345 (+)Ensembl
GRCm38.p6 Ensembl6128,971,160 - 128,983,382 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204259   ⟹   ENSMUSP00000144879
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,948,224 - 128,960,209 (+)Ensembl
GRCm38.p6 Ensembl6128,971,261 - 128,983,246 (+)Ensembl
RefSeq Acc Id: NM_001168223   ⟹   NP_001161695
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396128,948,123 - 128,961,670 (+)NCBI
GRCm386128,971,160 - 128,984,707 (+)NCBI
MGSCv376128,884,399 - 128,934,725 (+)RGD
Celera6130,636,744 - 130,692,143 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001168224   ⟹   NP_001161696
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396128,948,123 - 128,961,670 (+)NCBI
GRCm386128,971,160 - 128,984,707 (+)NCBI
MGSCv376128,884,399 - 128,934,725 (+)RGD
Celera6130,636,744 - 130,692,143 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001316752   ⟹   NP_001303681
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396128,948,123 - 128,961,670 (+)NCBI
GRCm386128,971,160 - 128,984,707 (+)NCBI
Sequence:
RefSeq Acc Id: NM_027562   ⟹   NP_081838
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396128,911,344 - 128,961,670 (+)NCBI
GRCm386128,934,381 - 128,984,707 (+)ENTREZGENE
MGSCv376128,884,399 - 128,934,725 (+)RGD
Celera6130,636,744 - 130,692,143 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_081838   ⟸   NM_027562
- Peptide Label: isoform 1
- UniProtKB: Q80Z35 (UniProtKB/Swiss-Prot),   Q3UUY2 (UniProtKB/Swiss-Prot),   Q1AFZ6 (UniProtKB/Swiss-Prot),   Q8BHH6 (UniProtKB/Swiss-Prot),   Q9D676 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001161695   ⟸   NM_001168223
- Peptide Label: isoform 2
- UniProtKB: A0A0N4SUR3 (UniProtKB/TrEMBL),   G3EZR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001161696   ⟸   NM_001168224
- Peptide Label: isoform 3
- UniProtKB: F5CSM6 (UniProtKB/TrEMBL),   G3EZR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001303681   ⟸   NM_001316752
- Peptide Label: isoform 4
- UniProtKB: F5CSM7 (UniProtKB/TrEMBL),   G3EZR8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000144879   ⟸   ENSMUST00000204259
Ensembl Acc Id: ENSMUSP00000144788   ⟸   ENSMUST00000203405
Ensembl Acc Id: ENSMUSP00000000254   ⟸   ENSMUST00000000254
Ensembl Acc Id: ENSMUSP00000075192   ⟸   ENSMUST00000075789
Ensembl Acc Id: ENSMUSP00000115140   ⟸   ENSMUST00000142388
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VI21-F1-model_v2 AlphaFold Q8VI21 1-196 view protein structure
AF-Q9D676-F1-model_v2 AlphaFold Q9D676 1-269 view protein structure

Promoters
RGD ID:6891164
Promoter ID:EPDNEW_M9033
Type:multiple initiation site
Name:Clec2g_1
Description:Mus musculus C-type lectin domain family 2, member g , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9035  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386128,934,358 - 128,934,418EPDNEW
RGD ID:6891168
Promoter ID:EPDNEW_M9035
Type:single initiation site
Name:Clec2g_2
Description:Mus musculus C-type lectin domain family 2, member g , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9033  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386128,974,597 - 128,974,657EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918059 AgrOrtholog
Ensembl Genes ENSMUSG00000000248 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000000254 ENTREZGENE
  ENSMUST00000000254.14 UniProtKB/Swiss-Prot
  ENSMUST00000075789.4 UniProtKB/Swiss-Prot
  ENSMUST00000142388 ENTREZGENE
  ENSMUST00000142388.8 UniProtKB/Swiss-Prot
  ENSMUST00000203405 ENTREZGENE
  ENSMUST00000203405.3 UniProtKB/TrEMBL
  ENSMUST00000204259 ENTREZGENE
  ENSMUST00000204259.3 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin/matrix_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NKR-like_CTLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:70809 UniProtKB/Swiss-Prot
MGD MGI:1918059 ENTREZGENE
NCBI Gene 70809 ENTREZGENE
PANTHER C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER D-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Clec2g PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUR3 ENTREZGENE, UniProtKB/TrEMBL
  CLC2G_MOUSE UniProtKB/Swiss-Prot
  F5CSM6 ENTREZGENE, UniProtKB/TrEMBL
  F5CSM7 ENTREZGENE, UniProtKB/TrEMBL
  G3EZR8 ENTREZGENE, UniProtKB/TrEMBL
  I1W6W7_MOUSE UniProtKB/TrEMBL
  Q1AFZ6 ENTREZGENE
  Q3UUY2 ENTREZGENE
  Q80Z35 ENTREZGENE
  Q8BHH6 ENTREZGENE
  Q8VI21 ENTREZGENE
  Q9D676 ENTREZGENE
UniProt Secondary Q1AFZ6 UniProtKB/Swiss-Prot
  Q3UUY2 UniProtKB/Swiss-Prot
  Q80Z35 UniProtKB/Swiss-Prot
  Q8BHH6 UniProtKB/Swiss-Prot