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Gene: Zfp459 (zinc finger protein 459) Mus musculus

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Symbol:

Zfp459

Name:

zinc finger protein 459

RGD ID:

1618790

MGI Page

MGI

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in cranial ganglion; dorsal root ganglion; early conceptus; and genitourinary system.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

9930025G17Rik; Rslc; Rslcan-14

RGD Orthologs

Human

Bonobo

Dog

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

Gm18175

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	67,553,831 - 67,569,537 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	67,553,828 - 67,569,537 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	67,405,033 - 67,443,302 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	67,405,709 - 67,421,418 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	67,506,658 - 67,572,531 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	67,904,819 - 67,920,515 (-)	NCBI		MGSCv36	mm8
Celera	13	69,887,098 - 69,902,813 (+)	NCBI		Celera
Cytogenetic Map	13	B3	NCBI
cM Map	13	34.54	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp459	Mouse	branched-chain keto acid dehydrogenase kinase deficiency		ISO	RGD:1602069	8554872	ClinVar Annotator: match by term: Branched-chain keto acid dehydrogenase kinase deficiency	ClinVar	PMID:25741868
Zfp459	Mouse	dilated cardiomyopathy		ISO	RGD:1602069	8554872	ClinVar Annotator: match by term: Dilated Cardiomyopathy, Dominant	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp459	Mouse	1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene	multiple interactions	EXP		6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Zfp459	Mouse	1,2-dimethylhydrazine	decreases expression	EXP		6480464	1,2-Dimethylhydrazine results in decreased expression of ZFP459 mRNA	CTD	PMID:22206623
Zfp459	Mouse	2,2',4,4',5,5'-hexachlorobiphenyl	multiple interactions	EXP		6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Zfp459	Mouse	2,2',5,5'-tetrachlorobiphenyl	multiple interactions	EXP		6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Zfp459	Mouse	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of ZFP459 mRNA	CTD	PMID:21570461
Zfp459	Mouse	2,4,4'-trichlorobiphenyl	multiple interactions	EXP		6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Zfp459	Mouse	2-hydroxypropanoic acid	increases expression	ISO	RGD:1602069	6480464	Lactic Acid results in increased expression of ZNF785 mRNA	CTD	PMID:30851411
Zfp459	Mouse	2-palmitoylglycerol	increases expression	ISO	RGD:1602069	6480464	2-palmitoylglycerol results in increased expression of ZNF785 mRNA	CTD	PMID:37199045
Zfp459	Mouse	azathioprine	increases expression	EXP		6480464	Azathioprine results in increased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	Bardoxolone methyl	increases expression	EXP		6480464	bardoxolone methyl results in increased expression of ZFP459 mRNA	CTD	PMID:25056779
Zfp459	Mouse	benzo[a]pyrene	decreases methylation	ISO	RGD:1602069	6480464	Benzo(a)pyrene results in decreased methylation of ZNF785 exon; Benzo(a)pyrene results in decreased methylation of ZNF785 more ...	CTD	PMID:27901495
Zfp459	Mouse	cadmium dichloride	decreases expression	ISO	RGD:1602069	6480464	Cadmium Chloride results in decreased expression of ZNF785 mRNA	CTD	PMID:38568856
Zfp459	Mouse	chlorpyrifos	decreases expression	EXP		6480464	Chlorpyrifos results in decreased expression of ZFP459 mRNA	CTD	PMID:37019170
Zfp459	Mouse	coumestrol	decreases expression	ISO	RGD:1602069	6480464	Coumestrol results in decreased expression of ZNF785 mRNA	CTD	PMID:19167446
Zfp459	Mouse	cyclophosphamide	increases expression	EXP		6480464	Cyclophosphamide results in increased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	cyclosporin A	increases expression	EXP		6480464	Cyclosporine results in increased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	dexamethasone	increases expression	EXP		6480464	Dexamethasone results in increased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	diazinon	increases methylation	ISO	RGD:1602069	6480464	Diazinon results in increased methylation of ZNF785 gene	CTD	PMID:22964155
Zfp459	Mouse	Dibutyl phosphate	affects expression	ISO	RGD:1602069	6480464	di-n-butylphosphoric acid affects the expression of ZNF785 mRNA	CTD	PMID:37042841
Zfp459	Mouse	dorsomorphin	multiple interactions	ISO	RGD:1602069	6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ...	CTD	PMID:27188386
Zfp459	Mouse	doxorubicin	increases expression	ISO	RGD:1602069	6480464	Doxorubicin results in increased expression of ZNF785 mRNA	CTD	PMID:29803840
Zfp459	Mouse	methotrexate	increases expression	EXP		6480464	Methotrexate results in increased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	panobinostat	decreases expression	ISO	RGD:1602069	6480464	Panobinostat results in decreased expression of ZNF785 mRNA	CTD	PMID:26272509
Zfp459	Mouse	panobinostat	multiple interactions	ISO	RGD:1602069	6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ...	CTD	PMID:27188386
Zfp459	Mouse	PCB138	multiple interactions	EXP		6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Zfp459	Mouse	phenylmercury acetate	multiple interactions	ISO	RGD:1602069	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Zfp459	Mouse	phenylmercury acetate	decreases expression	ISO	RGD:1602069	6480464	Phenylmercuric Acetate results in decreased expression of ZNF785 mRNA	CTD	PMID:26272509
Zfp459	Mouse	prednisolone	increases expression	EXP		6480464	Prednisolone results in increased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	rac-lactic acid	increases expression	ISO	RGD:1602069	6480464	Lactic Acid results in increased expression of ZNF785 mRNA	CTD	PMID:30851411
Zfp459	Mouse	SB 431542	multiple interactions	ISO	RGD:1602069	6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ...	CTD	PMID:27188386
Zfp459	Mouse	sodium dodecyl sulfate	decreases expression	EXP		6480464	Sodium Dodecyl Sulfate results in decreased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	tacrolimus hydrate	decreases expression	EXP		6480464	Tacrolimus results in decreased expression of ZFP459 mRNA	CTD	PMID:29362864
Zfp459	Mouse	tacrolimus hydrate	increases expression	EXP		6480464	Tacrolimus results in increased expression of ZFP459 mRNA	CTD	PMID:21621594
Zfp459	Mouse	valproic acid	affects expression	ISO	RGD:1602069	6480464	Valproic Acid affects the expression of ZNF785 mRNA	CTD	PMID:25979313
Zfp459	Mouse	valproic acid	decreases expression	ISO	RGD:1602069	6480464	Valproic Acid results in decreased expression of ZNF785 mRNA	CTD	PMID:23179753\|PMID:24383497\|PMID:24935251\|PMID:25192806\|PMID:26272509\|PMID:27188386\|PMID:28001369
Zfp459	Mouse	valproic acid	increases methylation	ISO	RGD:1602069	6480464	Valproic Acid results in increased methylation of ZNF785 gene	CTD	PMID:29154799
Zfp459	Mouse	valproic acid	multiple interactions	ISO	RGD:1602069	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp459	Mouse	regulation of transcription by RNA polymerase II	involved_in	IBA	PANTHER:PTN002810224\|MGI:3643133\|RGD:708346\|MGI:104748\|FB:FBgn0032979\|MGI:104786\|UniProtKB:P52736	2290270		GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp459	Mouse	nucleus	is_active_in	IBA	PANTHER:PTN002810224\|MGI:3583896\|UniProtKB:Q96N77\|UniProtKB:Q9UC06\|MGI:104786\|UniProtKB:P21506\|UniProtKB:Q9UJL9\|MGI:2442566\|UniProtKB:P13682\|UniProtKB:Q86TJ5\|MGI:104748\|FB:FBgn0032979\|MGI:1921650\|UniProtKB:Q96H86\|MGI:107794\|UniProtKB:Q9C0F3\|UniProtKB:Q6IV72	2290270		GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp459	Mouse	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA	PANTHER:PTN002810224\|MGI:104786\|RGD:708346\|FB:FBgn0032979	2290270		GO_Central	GO_REF:0000033
Zfp459	Mouse	protein binding	enables	ISO	UniProtKB:Q9UL42	9068941	PMID:33961781	IntAct	PMID:33961781
Zfp459	Mouse	protein binding	enables	ISO	UniProtKB:A2ABF9\|UniProtKB:P60370\|UniProtKB:Q5JR59\|UniProtKB:Q9UJC3\|UniProtKB:Q9UJV3-2	9068941	PMID:25416956	IntAct	PMID:25416956
Zfp459	Mouse	protein binding	enables	ISO	UniProtKB:Q5JR59	9068941	PMID:31515488	IntAct	PMID:31515488
Zfp459	Mouse	protein binding	enables	ISO	UniProtKB:A6NEM1\|UniProtKB:O76013-2\|UniProtKB:O95273\|UniProtKB:P07951-2\|UniProtKB:P32856-2\|UniProtKB:P59991\|UniProtKB:Q15654\|UniProtKB:Q16623\|UniProtKB:Q5JR59-3\|UniProtKB:Q8NA61-2\|UniProtKB:Q8NHQ1\|UniProtKB:Q99750\|UniProtKB:Q9BVG8-5\|UniProtKB:Q9NPB3\|UniProtKB:Q9UL42\|UniProtKB:Q9ULX6	9068941	PMID:32296183	IntAct	PMID:32296183
Zfp459	Mouse	RNA polymerase II transcription regulatory region sequence-specific DNA binding	enables	IBA	PANTHER:PTN002810224\|RGD:708346\|FB:FBgn0032979	2290270		GO_Central	GO_REF:0000033

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp459	Mouse	abnormal retina blood vessel morphology		IEA		5509061		MGI

#	Reference Title	Reference Citation
1.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:12520002	PMID:12904583	PMID:14563677	PMID:14610273	PMID:15618518	PMID:16141072
PMID:16141073	PMID:17967808	PMID:18799693	PMID:20059953	PMID:20412781	PMID:21267068	PMID:21677750	PMID:21873635	PMID:24194600	PMID:29997285	PMID:38355793

Zfp459
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	67,553,831 - 67,569,537 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	67,553,828 - 67,569,537 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	67,405,033 - 67,443,302 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	67,405,709 - 67,421,418 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	67,506,658 - 67,572,531 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	67,904,819 - 67,920,515 (-)	NCBI		MGSCv36	mm8
Celera	13	69,887,098 - 69,902,813 (+)	NCBI		Celera
Cytogenetic Map	13	B3	NCBI
cM Map	13	34.54	NCBI

ZNF785
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	30,578,361 - 30,585,697 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	30,573,740 - 30,585,769 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	30,591,977 - 30,597,018 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	30,499,495 - 30,504,511 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	29,701,399 - 29,706,415 (+)	NCBI		Celera
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	28,154,779 - 28,159,877 (-)	NCBI		HuRef
CHM1_1	16	31,909,181 - 31,914,278 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	30,965,340 - 30,972,758 (-)	NCBI		T2T-CHM13v2.0

ZNF785
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	33,781,403 - 33,794,710 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	38,582,839 - 38,596,606 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	24,382,132 - 24,388,335 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	30,953,485 - 30,957,279 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	30,953,485 - 30,957,279 (-)	Ensembl	panpan1.1		panPan2

ZNF785
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	17,565,330 - 17,569,490 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	17,565,260 - 17,568,684 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	19,139,619 - 19,143,785 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	17,696,728 - 17,700,896 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	17,496,899 - 17,501,057 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	17,411,969 - 17,416,136 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	17,727,204 - 17,731,362 (+)	NCBI		UU_Cfam_GSD_1.0

Variants in Zfp459
586 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	637
Count of miRNA genes:	463
Interacting mature miRNAs:	521
Transcripts:	ENSMUST00000056470
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300561	Heal7_m	wound healing/regeneration 7 (mouse)			Not determined		13	36144820	70144904	Mouse
4142331	Bxs6_m	BXSB/MpJ autoimmune nephritis 6 (mouse)			Not determined			45210442	83744746	Mouse
4142009	Pregq3_m	pregnancy QTL 3 (mouse)			Not determined		13	20615512	72385189	Mouse
1357587	Pfat3_m	predicted fat percentage 3 (mouse)			Not determined		13	36101530	70101640	Mouse
1300573	Elsgp2_m	elevated serum gp70 2 (mouse)			Not determined		13	50616828	84617027	Mouse
10412109	Bxs7_m	BXSB/MpJ autoimmune nephritis 7 (mouse)			Not determined		13	45210442	83744746	Mouse
10412235	Scgq5_m	spontaneous crescentic glomerulonephritis QTL 5 (mouse)			Not determined		13	36060908	96239162	Mouse
4142314	Tailaq3_m	tail length adjusted QTL 3 (mouse)			Not determined			55720354	112431103	Mouse
1558850	Sgp3_m	serum gp70 production 3 (mouse)			Not determined		13	56470456	76971314	Mouse
1301445	Listr2_m	listeriosis resistance 2 (mouse)			Not determined		13	66744601	100744746	Mouse
4141992	W6q16_m	weight 6 weeks QTL 16 (mouse)			Not determined			55720354	112431103	Mouse
4142372	Moo2_m	modifier of Odc2 (mouse)			Not determined		X	50318411	84318559	Mouse
15039353	Nmrs35_m	NAFLD-associated magnetic resonance shift 35 (mouse)					13	40588253	74588253	Mouse
10412163	Wra1_m	wheel running activity 1 (mouse)			Not determined		13	59132600	93132738	Mouse
1302157	Bwem2_m	body weight day 30 males 2 (mouse)			Not determined		13	39629249	73629397	Mouse
4142241	Tailq3_m	tail length QTL 3 (mouse)			Not determined			55720354	112431103	Mouse
1300941	Skl6_m	skeletal size (tail length) 6 (mouse)			Not determined		13	64250821	98250945	Mouse
1301299	Sluc23_m	susceptibility to lung cancer 23 (mouse)			Not determined		13	34921943	68922081	Mouse
4140959	W10q17_m	weight 10 weeks QTL 17 (mouse)			Not determined			55720354	112431103	Mouse
1357553	Cia28_m	collagen induced arthritis 28 (mouse)			Not determined		13	56629249	96239162	Mouse
1300985	Bmd13_m	bone mineral density 13 (mouse)			Not determined		13	39629249	73629397	Mouse
1302073	Pgct1_m	primordial germ cell tumor locus 1 (mouse)			Not determined		13	53820783	87820897	Mouse
1300862	Cfbw5_m	cystic fibrosis body weight 5 (mouse)			Not determined		13	38720358	72720517	Mouse
1301949	Skull20_m	skull morphology 20 (mouse)			Not determined		13	64250821	98250945	Mouse
1300668	Pas10_m	pulmonary adenoma susceptibility 10 (mouse)			Not determined		13	41489042	75489158	Mouse
1357563	Bmch6_m	bone mechanical trait 6 (mouse)			Not determined		13	55384980	89385140	Mouse
10402414	Sgp5_m	serum gp70 production 5 (mouse)			Not determined		13	56470456	105422186	Mouse
1301666	Eae13_m	susceptibility to experimental allergic encephalomyelitis 13 (mouse)			Not determined		13	50318411	84318559	Mouse
26884393	Humsd7_m	humerus midshaft diameter 7, 16 week (mouse)					13	3950000	76048119	Mouse
1301734	Acsns2_m	Angiostrongylus costaricensis nematode susceptibility 2 (mouse)			Not determined		13	36101530	70101640	Mouse
26884396	Humsd4_m	humerus midshaft diameter 4, 10 week (mouse)					13	47853476	73148119	Mouse
1301801	Cpfd5_m	cerebellum pattern fissures (mouse)			Not determined		13	39629249	73629397	Mouse
4142147	Mvwf4_m	modifier of von Willebrand factor 4 (mouse)			Not determined			20477612	112898424	Mouse
14746975	Manh74_m	mandible shape 74 (mouse)					13	52477269	86477269	Mouse

D13Mit98

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	13	67,468,709 - 67,468,908	UniSTS	GRCm38
MGSCv37	13	67,569,645 - 67,569,844	UniSTS	GRCm37
Celera	13	90,003,008 - 90,003,199	UniSTS
Celera	13	89,732,863 - 89,733,062	UniSTS
Cytogenetic Map	13	B3	UniSTS
cM Map	13	40.0	UniSTS
Whitehead Genetic	13	25.1	UniSTS

D13Mit66

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	13	67,170,347 - 67,170,495	UniSTS	GRCm38
MGSCv37	13	67,271,283 - 67,271,431	UniSTS	GRCm37
Celera	13	70,132,783 - 70,132,931	UniSTS
Celera	13	69,897,008 - 69,897,160	UniSTS
Cytogenetic Map	13	B3	UniSTS
cM Map	13	37.0	UniSTS
Whitehead Genetic	13	24.0	UniSTS
Whitehead/MRC_RH	13	929.46	UniSTS
Whitehead_YAC	13		UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_177811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC154510	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC164116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK036923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100389	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BK001628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000056470 ⟹ ENSMUSP00000063027

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	13	67,553,828 - 67,569,537 (-)	Ensembl
GRCm38.p6 Ensembl	13	67,405,709 - 67,421,418 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000223644 ⟹ ENSMUSP00000153490

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	13	67,556,659 - 67,569,518 (-)	Ensembl
GRCm38.p6 Ensembl	13	67,408,540 - 67,421,399 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000224113 ⟹ ENSMUSP00000153407

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	13	67,556,583 - 67,569,483 (-)	Ensembl
GRCm38.p6 Ensembl	13	67,408,464 - 67,421,364 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000224496

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	13	67,561,013 - 67,569,527 (-)	Ensembl
GRCm38.p6 Ensembl	13	67,412,894 - 67,421,408 (-)	Ensembl

RefSeq Acc Id:

NM_177811 ⟹ NP_808479

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	13	67,553,831 - 67,569,537 (-)	NCBI
GRCm38	13	67,405,712 - 67,421,418 (-)	NCBI
MGSCv37	13	67,506,658 - 67,572,531 (-)	RGD
Celera	13	69,887,098 - 69,902,823 (+)	ENTREZGENE
cM Map	13		ENTREZGENE

Sequence:

show sequence

AACACTCGTCAATCTTCCCGAAAGTTGGACTGGAGTCCTGTGATGCTGAAGATTCCTGTAGCATCTCTGACTTAGAGGAAATGCTGTCATTCAGGGATGTGGCCGTTGATTTCTCTGCAGAAGAGTGG
GAATGCCTGGAGCCTGCTCAGTGGCATCTGTACAGGGATGTGATGCTGGAGAATTACAGCCACCTTGTGTTCCTGGGGCTTGCTGACTCTAAGCCACAGCTGGTGACATTTCTGGAGCAAAGACAAGG
CTCTACTGGTGAAGAGAGACAAGCAGTAAAAGCAGTGTTCCCAGGAATAACACCCAATGATCCTAACCATTACAGCAAGCCCACTAATTGTGAATCACTCCTTCTTAAACGAAGAAGAATTAATACAG
GGGAGAAACCCTACAAGTGTGAAGAATGTGGTAAGGCCCTTAGTTCTCATAAAACACTTTCTATACACCAGAGACTTCATACTGGAGACAAACCCTACAAGTGTGAAGTGTGTCATAAGGCCTTCTGT
GCTCCCTCATCACTTTTTATACACCAGAAAAATCATACTGATGAAAAAAACTTCAAGTGTGAAGACTGTGGCAGAACATTTTACTATCTTTCAATGCTGAAGCAACATCAGAGAATTCATTCTGGGGA
GAAATGTTACAAGTGCAAAAATTGTGGATACGCTTCTTATGACCCTTCATTCCTTGAGCAGCATCAAAAAATTAATTGTAGGGAGAAATGCTACAAGTGTGAAGACTGTCACAAAGCCTTTCATCATC
AGCCCTTAGGATACACAAGAGAGTTCATACTGGAGAGAAACCTTTCAAATGTGAAAAGTGTGGCAGATGTTTTAGGGTATCTAAATCCCTTAAGCAACATAAAAAAATCCACTTAAAAAAGGAACCCT
ACACCTGCCAAGACTGTGGCAGATCTTTTTCAAATTATTTGAGACTTAGACGACATGAAGTGATTCATTCTGAATATAATCCTCACAAGTGTGAAAAATGTGACAAAAGGTTTTCCCATTCTGCAAAT
CTTCGGAACCATCAAAGAGTTCATAGTAGAGAGAGACCTTGCAAGTGTTAAGCATGTCACCAAGCCTTTTAAATATCGTTCAACCCTTTCGAAACACAAGAACACTCATGCAAGAGAGAAATCCTACC
AGTGTGAAGATGTGGTATGATGGTTTGTATATGCTTGGCTCAGGGAGTTGCAGTATTAGGAGGTGTGGCCTTGTTGGAGTAAGTGTGTCAATGTGGGTGTGGGGGTGGGCGCTAATACCCTTGTCCTA
CAAGCCAGTCTTGTAGCAGCCTTCAGATGAAGATGTACAACTCTTAGCTCTTCCTGCACCATGTCTGCCTGGATGCTGCCATGCTCCTGCCTTGATGATAATAGACTAAGTCTTTAATCTGTAAGCAA
GCCTCTATTAAGTGTTGTTCTTACAAGAGTTGCTTTGGTTATGGTGTCTGTTCACAGCAATAAACCCCTAAGACATATGGGAAGTGTGATAAAGCCTAGTTAATCTTGATAGCCTTACTCAACACAGG
ATAGTTCATAATGGAGTGAAGTCCTATGAATTTTTAAAATATTTAATCTTCTTCCACTCTTAAAACAAATCTGTGCTGCCCAGTTTTATGTCAGCTTGACAGGCAAACTAGAGCTATCTGAAAGGACA
GAACTTCAACTGAGTAAATGTTTGCATAAGATCCAGCTTTAACTGTTTTCTTAATTAGTGATTGATGGGAGGGCCCAGCCCATTGTGAGTGCGGTCATTCCTGAGCTGGGAGGCCTGGATTGTATAAG
AAAGCAGATTGAGCAGTCCATAGGGAGCAAGCATCCCTCCATGCCCTCCTCTATGTGAGTTCTTTTTTTTTTTTTTTTTGAGGCAGGTTTTTTCTGTGTAGCCCTGGCTGTCCTGGAACTCACTTTGT
AGACCAGGCTGGCCTCAAACTCAGAAATCCGCCTGCCTCTGCCTCCCAAGTGCTGGGATTAAAAGCGTGTGCCACCACGCCCGGCCCCTATGTGAGTTCTTGTCCTGGCTTCCTTTAATAATGGACTA
CAATGTGTTGGTGTAACTCAAACCCTTTCCTGCCCAACTTGCTTCAGTAGTAGTGTTTCTTAGAAGCAATAGGAACCCCAATTGACTGACTAAGGCAACACTCATTCTGACTACAAACTCCATGAGTG
TGTGGAATATGGTGAAATGTTTGCTAACAATTCAGATTTTATCCAATTCAAAAGGATCTGCAGTGAAGACTATTAAGTGAATTATTTTGGAATATCAACACAAACATCTTACTTCTAATAGCACAAAT
GCTAAGAAAGTCACCAGAAGCTGGGTGGTGGTGGTGCACACCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGTGGATTTCTGAGTTCGAGGCCAGCCTGGTCTACAAAGTGAGTTCCAGGACGGCC
GGGGCTATACAGAGAAACCCTGTCTCAAAACCCTCCTACCCCCCAAAAAAAGTCACCAGAGGAGTAGAGACTTCTCTTTGATGTAACCTCCCCACCAATGTGTTCAACCAATGTGCTTGAATCTTGCA
TGGATGGATGAGTTTCATCCCTCTGTAACTATATATATTTCATGAAACTGTTGCTCTGTTGTATAACTTGGTCCTTTGGGTGCCTGGAATCTGATTTGTGGGCTGTGGTACAGTTTCTGTTGTTTTAA
CCAGTGGCGGTGTCACCCATACTCTTTAAATAACGCATTCCCTGGGTGTGTAAGAAGCTCCATAAACTCACATTCCTCACCAACTTGGACTTTATGAAGATGATTTACATTGGATCTAATCTAAGCTA
ACTGGCCACTAGTGTTTGTGTCCCCAGGAAAAGCTAACAGAAATCATTGTCAGTTGTATTTGGCTTCAGAATGAAGAATCTCTTCATTTTCTTTAAACCTATAGATTGTTTTTCATATGACTCCAACT
GTCATGTCATAGAACTTGGCAGCATATTGAAATAATAATTGAAAAGATGCATTTGATTAGTATGTATATGATGTCAATCATGAAACATTGTAGATGCAGTTCTTACATAAATAACTATTGATAGGGAT
CCTAAAAGTGATCTCACAGTTGTGTTTATTCATTTATGGGAACACTTATATTAGGGCCATTAAAACCTAAAAGTTATCAGTCATTAACTTAGAAATGATCAAATATCTCTAATGTGCCCAAATTTTGT
TTTTAGTCATGCTAAGTATAAAATGAAATTTAATAAGTACAAGATGGGAGGGAGAGACCAATTTATATCTGTCATTTTATAGTTTTCTGTTTATACTATTAAATAAAGTACATCCTAAAACAAGTTTA
AAA

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Protein RefSeqs	NP_808479	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAC29640	(Get FASTA)	NCBI Sequence Viewer
	DAA01853	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000063027
	ENSMUSP00000063027.8
	ENSMUSP00000153407.2
	ENSMUSP00000153490.2

RefSeq Acc Id:

NP_808479 ⟸ NM_177811

- UniProtKB:

Q8BZ17 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSFRDVAVDFSAEEWECLEPAQWHLYRDVMLENYSHLVFLGLADSKPQLVTFLEQRQGSTGEERQAVKAVFPGITPNDPNHYSKPTNCESLLLKRRRINTGEKPYKCEECGKALSSHKTLSIHQRLH
TGDKPYKCEVCHKAFCAPSSLFIHQKNHTDEKNFKCEDCGRTFYYLSMLKQHQRIHSGEKCYKCKNCGYASYDPSFLEQHQKINCREKCYKCEDCHKAFHHQPLGYTREFILERNLSNVKSVADVLGY
LNPLSNIKKST

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Ensembl Acc Id:

ENSMUSP00000153490 ⟸ ENSMUST00000223644

Ensembl Acc Id:

ENSMUSP00000153407 ⟸ ENSMUST00000224113

Ensembl Acc Id:

ENSMUSP00000063027 ⟸ ENSMUST00000056470

Protein Domains

C2H2-type KRAB

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8BZ17-F1-model_v2	AlphaFold	Q8BZ17	1-267	view protein structure

RGD ID:

8680714

Promoter ID:

EPDNEW_M18387

Type:

initiation region

Name:

Zfp459_1

Description:

Mus musculus zinc finger protein 459 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	13	67,421,417 - 67,421,477	EPDNEW

RGD ID:

6824514

Promoter ID:

MM_KWN:14566

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Lung

Transcripts:

NM_177811

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	13	67,522,111 - 67,522,611 (-)	MPROMDB

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000055560	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000056470	ENTREZGENE
	ENSMUST00000056470.10	UniProtKB/TrEMBL
	ENSMUST00000223644.2	UniProtKB/TrEMBL
	ENSMUST00000224113.2	UniProtKB/TrEMBL
Gene3D-CATH	6.10.140.140	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	KRAB_dom_sf	UniProtKB/TrEMBL
	Krueppel-associated_box	UniProtKB/TrEMBL
	Krueppel_C2H2_ZnF	UniProtKB/TrEMBL
	Znf_C2H2-type	UniProtKB/TrEMBL
	Znf_C2H2/integrase_DNA-bd	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
KEGG Report	mmu:328274	UniProtKB/TrEMBL
MGD	MGI:3040701	ENTREZGENE
NCBI Gene	328274	ENTREZGENE
PANTHER	AA987161 PROTEIN	UniProtKB/TrEMBL
	KRAB DOMAIN C2H2 ZINC FINGER	UniProtKB/TrEMBL
	KRAB DOMAIN-CONTAINING PROTEIN 5	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN	UniProtKB/TrEMBL
	ZNF44 PROTEIN	UniProtKB/TrEMBL
Pfam	KRAB	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
PhenoGen	Zfp459	PhenoGen
PROSITE	KRAB	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	KRAB	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	Krueppel-associated_box	UniProtKB/TrEMBL
	SSF57667	UniProtKB/TrEMBL
UniProt	A0A286YDM7_MOUSE	UniProtKB/TrEMBL
	A0A286YDX0_MOUSE	UniProtKB/TrEMBL
	Q8BZ17	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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