Zfp526 (zinc finger protein 526) - Rat Genome Database

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Gene: Zfp526 (zinc finger protein 526) Mus musculus
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Symbol: Zfp526
Name: zinc finger protein 526
RGD ID: 1617393
MGI Page MGI
Description: Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Is expressed in genitourinary system. Orthologous to human ZNF526 (zinc finger protein 526).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D030024H03Rik; MGC106217; Znf526
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,919,272 - 24,929,688 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,920,850 - 24,926,932 (+)EnsemblGRCm39 Ensembl
GRCm38725,219,849 - 25,227,876 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,221,425 - 25,227,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv37726,006,470 - 26,012,524 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,930,211 - 24,936,267 (+)NCBIMGSCv36mm8
Celera719,836,754 - 19,842,809 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15368895   PMID:15618518   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:18287559   PMID:20059953   PMID:21873635  


Genomics

Comparative Map Data
Zfp526
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,919,272 - 24,929,688 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,920,850 - 24,926,932 (+)EnsemblGRCm39 Ensembl
GRCm38725,219,849 - 25,227,876 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,221,425 - 25,227,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv37726,006,470 - 26,012,524 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,930,211 - 24,936,267 (+)NCBIMGSCv36mm8
Celera719,836,754 - 19,842,809 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.73NCBI
ZNF526
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381942,220,312 - 42,228,201 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1942,220,292 - 42,228,201 (+)EnsemblGRCh38hg38GRCh38
GRCh371942,724,464 - 42,732,353 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,416,332 - 47,424,193 (+)NCBINCBI36Build 36hg18NCBI36
Celera1939,525,287 - 39,533,148 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1939,154,919 - 39,162,779 (+)NCBIHuRef
CHM1_11942,726,149 - 42,734,028 (+)NCBICHM1_1
T2T-CHM13v2.01945,039,686 - 45,047,575 (+)NCBIT2T-CHM13v2.0
Zfp526
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,935,604 - 89,945,669 (+)NCBIGRCr8
mRatBN7.2180,807,791 - 80,817,852 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,806,972 - 80,818,180 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0182,088,955 - 82,097,444 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,089,922 - 82,097,526 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,357,504 - 83,365,752 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera175,251,194 - 75,259,684 (+)NCBICelera
Cytogenetic Map1q21NCBI
Znf526
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555678,735 - 682,967 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955555678,735 - 682,967 (-)NCBIChiLan1.0ChiLan1.0
ZNF526
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,325,618 - 48,333,202 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11950,194,247 - 50,201,076 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01939,108,454 - 39,115,200 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,700,565 - 47,707,070 (+)NCBIpanpan1.1PanPan1.1panPan2
ZNF526
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,141,455 - 112,148,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,142,061 - 112,144,184 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,567,231 - 111,574,375 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,753,705 - 112,760,852 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,753,705 - 112,758,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,307,908 - 112,315,051 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,943,847 - 111,950,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,870,400 - 112,877,546 (-)NCBIUU_Cfam_GSD_1.0
Znf526
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,932,274 - 15,939,032 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706280,075 - 282,078 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706278,730 - 284,232 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF526
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,699,431 - 49,708,523 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,702,837 - 49,708,524 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,620,534 - 45,626,249 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF526
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,425,450 - 36,431,813 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,429,165 - 36,431,177 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607314,669,658 - 14,676,044 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf526
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907524,749 - 527,550 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907524,749 - 529,527 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp526
372 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:431
Count of miRNA genes:319
Interacting mature miRNAs:368
Transcripts:ENSMUST00000055604
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000055604   ⟹   ENSMUSP00000053567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,920,850 - 24,926,932 (+)Ensembl
GRCm38.p6 Ensembl725,221,425 - 25,227,507 (+)Ensembl
RefSeq Acc Id: NM_175436   ⟹   NP_780645
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,920,850 - 24,926,920 (+)NCBI
GRCm38725,221,425 - 25,227,495 (+)NCBI
MGSCv37726,006,470 - 26,012,524 (+)RGD
Celera719,836,754 - 19,842,809 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539713   ⟹   XP_006539776
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,919,272 - 24,929,688 (+)NCBI
GRCm38725,219,849 - 25,227,876 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006539715   ⟹   XP_006539778
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,920,879 - 24,929,688 (+)NCBI
GRCm38725,221,455 - 25,227,876 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006539716   ⟹   XP_006539779
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,920,850 - 24,929,688 (+)NCBI
GRCm38725,221,425 - 25,227,876 (+)NCBI
Sequence:
RefSeq Acc Id: NP_780645   ⟸   NM_175436
- UniProtKB: Q69Z58 (UniProtKB/Swiss-Prot),   Q4VA17 (UniProtKB/Swiss-Prot),   Q8BIH7 (UniProtKB/Swiss-Prot),   Q8BI66 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539776   ⟸   XM_006539713
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006539779   ⟸   XM_006539716
- Peptide Label: isoform X2
- UniProtKB: Q69Z58 (UniProtKB/Swiss-Prot),   Q4VA17 (UniProtKB/Swiss-Prot),   Q8BIH7 (UniProtKB/Swiss-Prot),   Q8BI66 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539778   ⟸   XM_006539715
- Peptide Label: isoform X2
- UniProtKB: Q69Z58 (UniProtKB/Swiss-Prot),   Q4VA17 (UniProtKB/Swiss-Prot),   Q8BIH7 (UniProtKB/Swiss-Prot),   Q8BI66 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000053567   ⟸   ENSMUST00000055604

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BI66-F1-model_v2 AlphaFold Q8BI66 1-675 view protein structure

Promoters
RGD ID:6892244
Promoter ID:EPDNEW_M9573
Type:multiple initiation site
Name:Zfp526_1
Description:Mus musculus zinc finger protein 526 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38725,221,441 - 25,221,501EPDNEW
RGD ID:6842390
Promoter ID:MM_KWN:49426
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000055604,   ENSMUST00000092652
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,005,531 - 26,006,572 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2445181 AgrOrtholog
Ensembl Genes ENSMUSG00000046541 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000055604 ENTREZGENE
  ENSMUST00000055604.6 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report mmu:210172 UniProtKB/Swiss-Prot
MGD MGI:2445181 ENTREZGENE
NCBI Gene 210172 ENTREZGENE
PANTHER C2H2-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
  zf-C2H2_4 UniProtKB/Swiss-Prot
PhenoGen Zfp526 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt Q4VA17 ENTREZGENE
  Q69Z58 ENTREZGENE
  Q8BI66 ENTREZGENE
  Q8BIH7 ENTREZGENE
  ZN526_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q4VA17 UniProtKB/Swiss-Prot
  Q69Z58 UniProtKB/Swiss-Prot
  Q8BIH7 UniProtKB/Swiss-Prot