Hells (helicase, lymphoid specific) - Rat Genome Database
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Gene: Hells (helicase, lymphoid specific) Mus musculus
Analyze
Symbol: Hells
Name: helicase, lymphoid specific
RGD ID: 1616865
Description: Exhibits chromatin binding activity. Involved in several processes, including DNA metabolic process; cellular response to leukemia inhibitory factor; and chromatin organization involved in negative regulation of transcription. Localizes to nucleus and pericentric heterochromatin. Is expressed in several structures, including central nervous system; gut; neural retina; reproductive system; and thymus. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 4. Orthologous to human HELLS (helicase, lymphoid specific); INTERACTS WITH (S)-nicotine; 1,2-dichloroethane; 1,4-dioxane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323785; E130115I21Rik; L; LSH; Ly; lymphocyte-specific helicase; Lysh; P; PASG; proliferation-associated SNF2-like protein; YFK8
Orthologs:
Homo sapiens (human) : HELLS (helicase, lymphoid specific)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hells (helicase, lymphoid specific)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hells (helicase, lymphoid specific)
Pan paniscus (bonobo/pygmy chimpanzee) : HELLS (helicase, lymphoid specific)
Canis lupus familiaris (dog) : HELLS (helicase, lymphoid specific)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hells (helicase, lymphoid specific)
Sus scrofa (pig) : HELLS (helicase, lymphoid specific)
Chlorocebus sabaeus (African green monkey) : HELLS (helicase, lymphoid specific)
Heterocephalus glaber (naked mole-rat) : Hells (helicase, lymphoid specific)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391938,913,282 - 38,958,914 (+)NCBI
GRCm381938,930,262 - 38,970,470 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1938,930,915 - 38,971,051 (+)EnsemblGRCm38mm10GRCm38
MGSCv371939,005,480 - 39,042,767 (+)NCBIGRCm37mm9NCBIm37
MGSCv361938,996,134 - 39,033,421 (+)NCBImm8
Celera1939,732,380 - 39,769,659 (+)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-nicotine  (EXP)
1,2-dichloroethane  (EXP)
1,4-dioxane  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-naphthyl isothiocyanate  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxynon-2-enal  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (EXP)
anthracene-1,8,9-triol  (EXP)
azathioprine  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
butylated hydroxyanisole  (EXP)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcitriol  (ISO)
carbon nanotube  (EXP)
cefaloridine  (ISO)
chlorpyrifos  (EXP)
cholic acid  (EXP)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dioxygen  (ISO)
Enterolactone  (ISO)
flurbiprofen  (EXP)
formaldehyde  (ISO)
glafenine  (ISO)
glycerol 2-phosphate  (ISO)
indole-3-methanol  (ISO)
irinotecan  (ISO)
iron dichloride  (EXP)
iron trichloride  (EXP)
L-ascorbic acid  (ISO)
Lasiocarpine  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Mezerein  (EXP)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nicotine  (EXP)
oxaliplatin  (ISO)
ozone  (EXP)
palytoxin  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (EXP,ISO)
progesterone  (EXP,ISO)
quercetin  (ISO)
resveratrol  (ISO)
saccharin  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium nitrite  (EXP)
styrene oxide  (EXP)
succimer  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
topotecan  (ISO)
tremolite asbestos  (EXP)
trichloroethene  (ISO)
trimellitic anhydride  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axial skeleton morphology  (IAGP)
abnormal chromosome morphology  (IAGP)
abnormal chromosome number  (IAGP)
abnormal coat/hair pigmentation  (IAGP)
abnormal DNA methylation  (IAGP)
abnormal DNA methylation during gametogenesis  (IAGP)
abnormal gait  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal locomotor activation  (IEA)
abnormal long bone epiphysis morphology  (IAGP)
abnormal long bone morphology  (IAGP)
abnormal meiosis  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal renal tubule morphology  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal tibia morphology  (IAGP)
alopecia  (IAGP)
arrest of male meiosis  (IAGP)
atelectasis  (IAGP)
cachexia  (IAGP)
decreased B cell number  (IAGP)
decreased birth weight  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased cell proliferation  (IAGP)
decreased cellular sensitivity to gamma-irradiation  (IAGP)
decreased circulating cholesterol level  (IEA)
decreased circulating LDL cholesterol level  (IEA)
decreased circulating triglyceride level  (IEA)
decreased embryo weight  (IAGP)
decreased fetal weight  (IAGP)
decreased granulocyte number  (IEA)
decreased IgG1 level  (IEA)
decreased male germ cell number  (IAGP)
decreased subcutaneous adipose tissue amount  (IAGP)
decreased testis weight  (IAGP)
delayed bone ossification  (IAGP)
delayed endochondral bone ossification  (IAGP)
dilated renal tubules  (IAGP)
hyperkeratosis  (IAGP)
hypoglycemia  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased double-negative T cell number  (IAGP)
increased male germ cell apoptosis  (IAGP)
increased renal tubule apoptosis  (IAGP)
kyphosis  (IAGP)
male infertility  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
osteoporosis  (IAGP)
paternal imprinting  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature aging  (IAGP)
renal tubular necrosis  (IAGP)
respiratory failure  (IAGP)
short femur  (IAGP)
short tibia  (IAGP)
small kidney  (IAGP)
small spleen  (IAGP)
small thymus  (IAGP)
thymus hypoplasia  (IAGP)
References

Additional References at PubMed
PMID:8647447   PMID:9878251   PMID:10349636   PMID:10781083   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11325543   PMID:11357197   PMID:11555636   PMID:11711429  
PMID:12466851   PMID:12471446   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14517253   PMID:14610273   PMID:14612388   PMID:15226823   PMID:15448183   PMID:15489334   PMID:15647320  
PMID:16141072   PMID:16141073   PMID:16395332   PMID:17115026   PMID:17726103   PMID:18487951   PMID:18799693   PMID:20161795   PMID:20362541   PMID:20362542   PMID:20439489   PMID:20439742  
PMID:21149390   PMID:21349825   PMID:21427231   PMID:21589869   PMID:21677750   PMID:21873635   PMID:22083510   PMID:22516201   PMID:22770845   PMID:22946062   PMID:24194600   PMID:24457600  
PMID:24711395   PMID:25170028   PMID:27179028   PMID:27626380   PMID:28378742   PMID:28442710   PMID:28621576   PMID:30516846   PMID:31493975   PMID:31970665   PMID:32001511   PMID:32325033  
PMID:32727902   PMID:32900989  


Genomics

Comparative Map Data
Hells
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391938,913,282 - 38,958,914 (+)NCBI
GRCm381938,930,262 - 38,970,470 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1938,930,915 - 38,971,051 (+)EnsemblGRCm38mm10GRCm38
MGSCv371939,005,480 - 39,042,767 (+)NCBIGRCm37mm9NCBIm37
MGSCv361938,996,134 - 39,033,421 (+)NCBImm8
Celera1939,732,380 - 39,769,659 (+)NCBICelera
Cytogenetic Map19C3NCBI
HELLS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1094,501,434 - 94,613,905 (+)EnsemblGRCh38hg38GRCh38
GRCh381094,545,778 - 94,613,905 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371096,305,535 - 96,362,628 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361096,295,564 - 96,351,846 (+)NCBINCBI36hg18NCBI36
Build 341096,295,563 - 96,351,845NCBI
Celera1090,045,660 - 90,101,938 (+)NCBI
Cytogenetic Map10q23.33NCBI
HuRef1089,932,081 - 89,988,296 (+)NCBIHuRef
CHM1_11096,587,324 - 96,643,612 (+)NCBICHM1_1
Hells
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01257,901,856 - 257,953,889 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1257,766,691 - 257,949,183 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1257,614,731 - 257,791,728 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01265,357,043 - 265,402,172 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,246,843 - 243,262,459 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1233,793,113 - 233,835,276 (+)NCBICelera
Cytogenetic Map1q53NCBI
Hells
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955507990,429 - 1,034,852 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955507995,389 - 1,034,852 (+)NCBIChiLan1.0ChiLan1.0
HELLS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11094,790,137 - 94,847,209 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1094,790,292 - 94,847,209 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01091,282,330 - 91,344,156 (+)NCBIMhudiblu_PPA_v0panPan3
HELLS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl288,661,008 - 8,705,580 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1288,660,866 - 8,705,570 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Hells
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936601626,354 - 662,477 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HELLS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14105,923,552 - 105,966,998 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114105,923,727 - 105,967,003 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214115,770,403 - 115,812,864 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HELLS
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl987,796,502 - 87,834,619 (+)Ensembl
ChlSab1.1987,780,897 - 87,835,087 (+)NCBI
Hells
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247375,892,705 - 5,954,364 (+)NCBI

Position Markers
AI323785  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381073,142,414 - 73,142,704UniSTSGRCm38
GRCm381938,967,873 - 38,968,157UniSTSGRCm38
MGSCv371939,042,363 - 39,042,647UniSTSGRCm37
MGSCv371072,605,162 - 72,605,452UniSTSGRCm37
Celera1939,769,255 - 39,769,539UniSTS
Celera1074,209,177 - 74,209,467UniSTS
Cytogenetic Map19C3-D1UniSTS
Whitehead/MRC_RH19370.21UniSTS
UniSTS:237938  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381938,965,568 - 38,965,865UniSTSGRCm38
MGSCv371939,040,058 - 39,040,355UniSTSGRCm37
Celera1939,766,937 - 39,767,234UniSTS
Cytogenetic Map19C3-D1UniSTS
Hells  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-D1UniSTS
cM Map19 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19533596239336106Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19932831543328421Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19981005343810202Mouse
14928311Manh85_mmandible shape 85 (mouse)191193738945937389Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191494561648945738Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191593520749935319Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191593520749935319Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191831776252317981Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191831776252317981Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192025691554257062Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192025691554257062Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192139025755390480Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192233596253923073Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192500000059000000Mouse
1302123Tlsr8_mthymic lymphoma suppressor region 8 (mouse)Not determined192515863842400477Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192543847859438566Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192739715561397266Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2815190961431566Mouse
4141562Pas3b_mpulmonary adenoma susceptibility 3b (mouse)Not determined2977296261431566Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193015278561431566Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193015279261431566Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193015279261431566Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193090944161431566Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193300371961431566Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193396351461431566Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3460834861431566Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193603954446773082Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193676416661431566Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193789455061431566Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193838761861431566Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir468mmu-miR-468-3pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI19959559

Predicted Target Of
Summary Value
Count of predictions:1082
Count of miRNA genes:615
Interacting mature miRNAs:749
Transcripts:ENSMUST00000025965, ENSMUST00000127968, ENSMUST00000128949, ENSMUST00000138292, ENSMUST00000145051, ENSMUST00000155465
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC101775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02162533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF155210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC090671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U25691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000025965   ⟹   ENSMUSP00000025965
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1938,930,915 - 38,971,051 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127968
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1938,943,689 - 38,950,475 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128949
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1938,934,508 - 38,940,601 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138292
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1938,931,030 - 38,940,500 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145051   ⟹   ENSMUSP00000116710
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1938,931,174 - 38,943,914 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155465
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1938,931,390 - 38,953,609 (+)Ensembl
RefSeq Acc Id: NM_008234   ⟹   NP_032260
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391938,919,434 - 38,956,721 (+)NCBI
GRCm381938,930,990 - 38,968,277 (+)NCBI
MGSCv371939,005,480 - 39,042,767 (+)RGD
Celera1939,732,380 - 39,769,659 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006526699   ⟹   XP_006526762
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391938,913,282 - 38,958,914 (+)NCBI
GRCm381938,930,262 - 38,970,470 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006526700   ⟹   XP_006526763
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391938,936,000 - 38,958,914 (+)NCBI
GRCm381938,947,555 - 38,970,470 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032260   ⟸   NM_008234
- UniProtKB: Q60848 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006526762   ⟸   XM_006526699
- Peptide Label: isoform X1
- UniProtKB: Q60848 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006526763   ⟸   XM_006526700
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000116710   ⟸   ENSMUST00000145051
RefSeq Acc Id: ENSMUSP00000025965   ⟸   ENSMUST00000025965
Promoters
RGD ID:13679416
Promoter ID:EPDNEW_M23857
Type:initiation region
Name:Hells_1
Description:Mus musculus helicase, lymphoid specific , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381938,930,957 - 38,931,017EPDNEW
RGD ID:6830118
Promoter ID:MM_KWN:26991
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000050285,   OTTMUST00000050287,   OTTMUST00000050288,   OTTMUST00000050290
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361939,005,164 - 39,005,664 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106209 AgrOrtholog
Ensembl Genes ENSMUSG00000025001 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000025965 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000116710 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000025965 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000145051 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10810 UniProtKB/Swiss-Prot
InterPro Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  SNF2-like_sf UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
KEGG Report mmu:15201 UniProtKB/Swiss-Prot
MGD MGI:106209 ENTREZGENE
NCBI Gene 15201 ENTREZGENE
Pfam Helicase_C UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
PhenoGen Hells PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
SMART DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniGene Mm.392920 ENTREZGENE
  Mm.486446 ENTREZGENE
  Mm.57223 ENTREZGENE
UniProt D3Z414_MOUSE UniProtKB/TrEMBL
  HELLS_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q497T3 UniProtKB/Swiss-Prot
  Q8VDZ1 UniProtKB/Swiss-Prot
  Q9CYV7 UniProtKB/Swiss-Prot