Ovol3 (ovo like zinc finger 3) - Rat Genome Database

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Gene: Ovol3 (ovo like zinc finger 3) Mus musculus
Analyze
Symbol: Ovol3
Name: ovo like zinc finger 3
RGD ID: 1616395
MGI Page MGI
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in epidermal cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human OVOL3 (ovo like zinc finger 3).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Gm1903; mo; movo3; OVO homolog-like 3; putative transcription factor ovo-like protein 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39729,932,722 - 29,937,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl729,932,864 - 29,935,150 (-)EnsemblGRCm39 Ensembl
GRCm38730,233,297 - 30,237,575 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,233,439 - 30,235,725 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,018,458 - 31,020,478 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36729,942,199 - 29,944,119 (-)NCBIMGSCv36mm8
MGSCv36722,511,594 - 22,513,514 (-)NCBIMGSCv36mm8
Celera724,837,823 - 24,839,843 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map717.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12213202   PMID:14610273   PMID:15716349   PMID:17062627   PMID:21873635   PMID:22737237  


Genomics

Comparative Map Data
Ovol3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39729,932,722 - 29,937,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl729,932,864 - 29,935,150 (-)EnsemblGRCm39 Ensembl
GRCm38730,233,297 - 30,237,575 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,233,439 - 30,235,725 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,018,458 - 31,020,478 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36729,942,199 - 29,944,119 (-)NCBIMGSCv36mm8
MGSCv36722,511,594 - 22,513,514 (-)NCBIMGSCv36mm8
Celera724,837,823 - 24,839,843 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map717.34NCBI
OVOL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381936,111,143 - 36,113,711 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1936,111,143 - 36,113,711 (+)EnsemblGRCh38hg38GRCh38
GRCh371936,602,045 - 36,604,613 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361941,287,925 - 41,296,403 (+)NCBINCBI36Build 36hg18NCBI36
Celera1933,316,285 - 33,318,744 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1933,107,590 - 33,110,099 (+)NCBIHuRef
CHM1_11936,603,447 - 36,605,955 (+)NCBICHM1_1
T2T-CHM13v2.01938,656,961 - 38,659,529 (+)NCBIT2T-CHM13v2.0
Ovol3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,612,417 - 94,616,053 (-)NCBIGRCr8
mRatBN7.2185,484,956 - 85,488,592 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,484,956 - 85,488,592 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx190,901,557 - 90,905,174 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,368,921 - 99,372,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0192,659,818 - 92,663,435 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0191,037,531 - 91,041,167 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl191,038,886 - 91,041,121 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,688,299 - 88,690,534 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0192,174,474 - 92,178,324 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera179,859,395 - 79,863,031 (-)NCBICelera
Cytogenetic Map1q21NCBI
Ovol3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554682,495,567 - 2,498,508 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554682,495,567 - 2,498,508 (-)NCBIChiLan1.0ChiLan1.0
OVOL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22042,112,976 - 42,115,735 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11944,096,533 - 44,099,284 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01933,030,285 - 33,032,988 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,777,055 - 41,780,124 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,777,055 - 41,780,124 (+)Ensemblpanpan1.1panPan2
OVOL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,587,569 - 116,594,086 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,587,599 - 116,589,497 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1115,992,945 - 115,999,678 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01117,190,335 - 117,197,055 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,190,570 - 117,192,468 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11116,757,730 - 116,764,462 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,377,910 - 116,384,643 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,433,080 - 117,439,809 (-)NCBIUU_Cfam_GSD_1.0
Ovol3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934911,357,768 - 11,360,128 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936922128,196 - 130,197 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936922128,196 - 130,197 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OVOL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,478,098 - 45,480,786 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1645,477,261 - 45,480,822 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,878,391 - 40,882,993 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OVOL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1631,016,622 - 31,020,104 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660738,817,498 - 8,820,290 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ovol3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479410,357,829 - 10,359,935 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479410,355,883 - 10,360,083 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ovol3
123 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
7394747asp3_maudiogenic seizure prone 3 (mouse)Not determined72730579836842367Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse

Markers in Region
RH139378  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38730,233,000 - 30,233,070UniSTSGRCm38
MGSCv37731,018,019 - 31,018,089UniSTSGRCm37
Celera724,837,384 - 24,837,454UniSTS
Cytogenetic Map7B1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000189482   ⟹   ENSMUSP00000140811
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl729,932,864 - 29,935,150 (-)Ensembl
GRCm38.p6 Ensembl730,233,439 - 30,235,725 (-)Ensembl
RefSeq Acc Id: NM_001289817   ⟹   NP_001276746
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39729,932,722 - 29,936,190 (-)NCBI
GRCm38730,233,297 - 30,236,765 (-)NCBI
Celera724,837,681 - 24,841,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036153197   ⟹   XP_036009090
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39729,932,848 - 29,937,000 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001276746 (Get FASTA)   NCBI Sequence Viewer  
  XP_036009090 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D3YYM0 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000140811
  ENSMUSP00000140811.2
Reference Protein Sequences
RefSeq Acc Id: NP_001276746   ⟸   NM_001289817
- UniProtKB: D3YYM0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000140811   ⟸   ENSMUST00000189482
RefSeq Acc Id: XP_036009090   ⟸   XM_036153197
- Peptide Label: isoform X1
- UniProtKB: D3YYM0 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3YYM0-F1-model_v2 AlphaFold D3YYM0 1-189 view protein structure

Promoters
RGD ID:6841713
Promoter ID:MM_KWN:49787
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney
Transcripts:ENSMUST00000047308,   XM_355880_OVOL3
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36731,020,446 - 31,020,997 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2388075 AgrOrtholog
Ensembl Genes ENSMUSG00000100512 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000189482 ENTREZGENE
  ENSMUST00000189482.2 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro Ovo-like UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report mmu:381867 UniProtKB/Swiss-Prot
MGD MGI:2388075 ENTREZGENE
NCBI Gene 381867 ENTREZGENE
PANTHER PTHR10032 UniProtKB/Swiss-Prot
  TRANSCRIPTION FACTOR OVO-LIKE PROTEIN 3-RELATED UniProtKB/Swiss-Prot
Pfam zf-H2C2_2 UniProtKB/Swiss-Prot
PhenoGen Ovol3 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt D3YYM0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Ovol3  ovo like zinc finger 3    OVO homolog-like 3 (Drosophila)  Symbol and/or name change 5135510 APPROVED