Gpr31b (G protein-coupled receptor 31, D17Leh66b region) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gpr31b (G protein-coupled receptor 31, D17Leh66b region) Mus musculus
Analyze
Symbol: Gpr31b
Name: G protein-coupled receptor 31, D17Leh66b region
RGD ID: 1616350
MGI Page MGI
Description: Enables bioactive lipid receptor activity. Involved in several processes, including negative regulation of inflammatory response; response to ischemia; and response to molecule of bacterial origin. Predicted to be located in plasma membrane. Orthologous to human GPR31 (G protein-coupled receptor 31).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 12-(S)-HETE receptor; 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; 12-HETER; EG667359; G protein-coupled receptor 31, D17Leh66c region; G-protein coupled receptor 31; Gm8593; Gpr31; Gpr31c; GPR31c(t); probable G-protein coupled receptor 31
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm6553   Gpr31a  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,270,208 - 13,271,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,565,094 - 13,566,048 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1713,269,901 - 13,271,183 (-)EnsemblGRCm39 Ensembl
GRCm381713,051,321 - 13,052,280 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1713,051,014 - 13,052,296 (-)EnsemblGRCm38mm10GRCm38
MGSCv371713,244,187 - 13,245,146 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,894,253 - 12,895,212 (-)NCBIMGSCv36mm8
Cytogenetic Map17A1NCBI
cM Map178.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (ISO,ISS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10501965   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21873635   PMID:29227475   PMID:30675063   PMID:32325033  
PMID:35303081  


Genomics

Comparative Map Data
Gpr31b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,270,208 - 13,271,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,565,094 - 13,566,048 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1713,269,901 - 13,271,183 (-)EnsemblGRCm39 Ensembl
GRCm381713,051,321 - 13,052,280 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1713,051,014 - 13,052,296 (-)EnsemblGRCm38mm10GRCm38
MGSCv371713,244,187 - 13,245,146 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,894,253 - 12,895,212 (-)NCBIMGSCv36mm8
Cytogenetic Map17A1NCBI
cM Map178.76NCBI
GPR31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386167,155,247 - 167,157,980 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6167,155,247 - 167,157,980 (-)EnsemblGRCh38hg38GRCh38
GRCh376167,568,735 - 167,571,468 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366167,490,350 - 167,491,309 (-)NCBINCBI36Build 36hg18NCBI36
Build 346167,540,770 - 167,541,730NCBI
Celera6168,312,713 - 168,313,672 (-)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6165,042,993 - 165,043,952 (-)NCBIHuRef
CHM1_16167,832,742 - 167,833,701 (-)NCBICHM1_1
T2T-CHM13v2.06168,537,922 - 168,540,655 (-)NCBIT2T-CHM13v2.0
Gpr31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8155,474,484 - 55,475,443 (-)NCBIGRCr8
mRatBN7.2152,926,953 - 52,927,912 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx153,634,921 - 53,635,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0159,619,793 - 59,620,752 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,710,524 - 53,711,483 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0153,519,829 - 53,520,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl153,519,829 - 53,520,788 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0154,767,584 - 54,768,543 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,581,861 - 47,582,820 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1147,584,805 - 47,585,765 (-)NCBI
Celera148,687,120 - 48,688,079 (-)NCBICelera
Cytogenetic Map1q12NCBI
Gpr31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543914,906,304 - 14,907,574 (+)NCBIChiLan1.0ChiLan1.0
GPR31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25187,367,870 - 187,370,602 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16185,263,793 - 185,266,523 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl6170,103,890 - 170,104,849 (-)Ensemblpanpan1.1panPan2
GPR31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,974,711 - 54,977,251 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl154,976,178 - 54,977,128 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,764,274 - 55,766,869 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0155,155,569 - 55,158,164 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl155,157,045 - 55,157,995 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1155,052,473 - 55,055,068 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,900,934 - 54,903,529 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0155,526,148 - 55,528,739 (-)NCBIUU_Cfam_GSD_1.0
Gpr31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946149,449,961 - 149,451,007 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648916,702,084 - 16,703,000 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648916,702,024 - 16,703,000 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl12,003,172 - 2,008,112 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.112,002,241 - 2,008,114 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103240927
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11394,908,329 - 94,915,359 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1394,913,071 - 94,914,030 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604066,707,867 - 66,710,401 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpr31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478512,155,797 - 12,158,107 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:55
Interacting mature miRNAs:56
Transcripts:ENSMUST00000091648
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171263668226401133Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1219832925076769Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120975022Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120975022Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000091648   ⟹   ENSMUSP00000089237
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,269,901 - 13,271,183 (-)Ensembl
GRCm38.p6 Ensembl1713,051,014 - 13,052,296 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233475
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,565,094 - 13,566,048 (-)Ensembl
RefSeq Acc Id: NM_001013832   ⟹   NP_001013854
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,270,208 - 13,271,167 (-)NCBI
GRCm381713,051,321 - 13,052,280 (-)ENTREZGENE
MGSCv371713,244,187 - 13,245,146 (-)RGD
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001013854 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF26668 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000089237
  ENSMUSP00000089237.3
GenBank Protein F8VQN3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001013854   ⟸   NM_001013832
- UniProtKB: Q9JLS1 (UniProtKB/Swiss-Prot),   F8VQN3 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000089237   ⟸   ENSMUST00000091648

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F8VQN3-F1-model_v2 AlphaFold F8VQN3 1-319 view protein structure

Promoters
RGD ID:13674776
Promoter ID:EPDNEW_M21537
Type:initiation region
Name:Gpr31b_1
Description:Mus musculus G protein-coupled receptor 31, D17Leh66b region, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381713,052,296 - 13,052,356EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354372 AgrOrtholog
Ensembl Genes ENSMUSG00000071311 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSG00000117239 Ensembl
Ensembl Transcript ENSMUST00000091648 ENTREZGENE
  ENSMUST00000091648.4 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  HCARs UniProtKB/Swiss-Prot
KEGG Report mmu:436440 UniProtKB/Swiss-Prot
MGD MGI:1354372 ENTREZGENE
NCBI Gene Gpr31b ENTREZGENE
PANTHER 12-(S)-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID RECEPTOR UniProtKB/Swiss-Prot
  HYDROXYCARBOXYLIC ACID RECEPTOR 2 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Gpr31b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt F8VQN3 ENTREZGENE, UniProtKB/Swiss-Prot
  Q9JLS1 ENTREZGENE
UniProt Secondary Q9JLS1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-05 Gpr31b  G protein-coupled receptor 31, D17Leh66b region  Gpr31c  G protein-coupled receptor 31, D17Leh66c region  Data Merged 737654 PROVISIONAL
2014-09-17 Gpr31b  G protein-coupled receptor 31, D17Leh66b region  Gpr31c  G protein-coupled receptor 31, D17Leh66c region  Symbol and/or name change 5135510 APPROVED
2014-09-17 Gpr31c  G protein-coupled receptor 31, D17Leh66c region  Gm8593  predicted gene 8593  Symbol and/or name change 5135510 APPROVED