Prb1c (proline-rich protein BstNI subfamily 1C) - Rat Genome Database

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Gene: Prb1c (proline-rich protein BstNI subfamily 1C) Mus musculus
Analyze
No known orthologs.
Symbol: Prb1c
Name: proline-rich protein BstNI subfamily 1C
RGD ID: 1615255
MGI Page MGI
Description: Orthologous to several human genes including PRR4 (proline rich 4); PRB1 (proline rich protein BstNI subfamily 1); and PRB2 (proline rich protein BstNI subfamily 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG667929; Gm8882; proline-rich protein BstNI subfamily 1-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396132,338,068 - 132,341,097 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6132,338,004 - 132,341,097 (-)EnsemblGRCm39 Ensembl
GRCm386132,361,105 - 132,364,134 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6132,361,041 - 132,364,134 (-)EnsemblGRCm38mm10GRCm38
MGSCv376132,311,420 - 132,314,125 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366132,327,095 - 132,329,845 (-)NCBIMGSCv36mm8
Celera6133,500,624 - 133,503,652 (+)NCBICelera
Cytogenetic Map6G1NCBI
cM Map664.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Variants

.
Variants in Prb1c
126 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:85
Interacting mature miRNAs:85
Transcripts:ENSMUST00000080849
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125333609134096586Mouse
10412134Cmv4_mcytomegalovirus resistance 4 (mouse)Not determined6127815180136022150Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
4141151Ath38_matherosclerosis 38 (mouse)Not determined128495857136293176Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128601582149588044Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128601582149588044Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128601582149588044Mouse
10412215Cmv3_mcytomegalovirus resistance 3 (mouse)Not determined6128811857137416927Mouse
1301084Bpq5_mblood pressure QTL 5 (mouse)Not determined6129330484149588044Mouse
4141974Skmw14_mskeletal muscle weight 14 (mouse)Not determined6129330484149588044Mouse
1301686Trmq1_mT cell ratio modifier QTL 1 (mouse)Not determined6129330484149588044Mouse
1301620Insq8_minsulin QTL 8 (mouse)Not determined6129534979149588044Mouse
1558959Eamcd2_mexperimental autoimmune myocarditis 2 (mouse)Not determined6129953954149588044Mouse
14746990Manh61_mmandible shape 61 (mouse)6130156355149588044Mouse
14746999Mancz6_mmandible centroid size 6 (mouse)6130156355149588044Mouse
12879916Shm5_msperm head morphology 5 (mouse)6132266532145601739Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000080849   ⟹   ENSMUSP00000079660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6132,338,004 - 132,341,097 (-)Ensembl
GRCm38.p6 Ensembl6132,361,041 - 132,364,134 (-)Ensembl
RefSeq Acc Id: NM_001177588   ⟹   NP_001171059
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396132,338,068 - 132,341,097 (-)NCBI
GRCm386132,361,105 - 132,364,134 (-)ENTREZGENE
Celera6133,500,624 - 133,503,652 (+)ENTREZGENE
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001171059 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI71935 (Get FASTA)   NCBI Sequence Viewer  
  AAI71936 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000079660
  ENSMUSP00000079660.6
Reference Protein Sequences
RefSeq Acc Id: NP_001171059   ⟸   NM_001177588
- Peptide Label: precursor
- UniProtKB: E9Q7E4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000079660   ⟸   ENSMUST00000080849

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9Q7E4-F1-model_v2 AlphaFold E9Q7E4 1-283 view protein structure

Promoters
RGD ID:6891324
Promoter ID:EPDNEW_M9080
Type:single initiation site
Name:Gm8882_1
Description:Mus musculus predicted gene 8882 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386132,364,131 - 132,364,191EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3645847 AgrOrtholog
Ensembl Genes ENSMUSG00000030143 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000080849 ENTREZGENE
  ENSMUST00000080849.6 UniProtKB/TrEMBL
InterPro Pro-rich UniProtKB/TrEMBL
KEGG Report mmu:667929 UniProtKB/TrEMBL
MGD MGI:3645847 ENTREZGENE
NCBI Gene 667929 ENTREZGENE
PANTHER PROLINE-RICH PROTEIN BSTNI SUBFAMILY 1-RELATED UniProtKB/TrEMBL
  PTHR23203 UniProtKB/TrEMBL
Pfam Pro-rich UniProtKB/TrEMBL
PhenoGen Prb1c PhenoGen
SMART Pro-rich UniProtKB/TrEMBL
UniProt B7ZW90_MOUSE UniProtKB/TrEMBL
  E9Q7E4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-24 Prb1c  proline-rich protein BstNI subfamily 1C  Gm8882  predicted gene 8882  Symbol and/or name updated 27372883 PROVISIONAL