Or8c10 (olfactory receptor family 8 subfamily C member 10) - Rat Genome Database

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Gene: Or8c10 (olfactory receptor family 8 subfamily C member 10) Mus musculus
Analyze
No known orthologs.
Symbol: Or8c10
Name: olfactory receptor family 8 subfamily C member 10
RGD ID: 1613234
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2MYUG-19447-18473; MOR170-; MOR170-14; olfactory receptor 250; Olfr250
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39938,278,844 - 38,279,839 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl938,278,192 - 38,282,651 (+)EnsemblGRCm39 Ensembl
GRCm38938,367,548 - 38,368,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl938,366,896 - 38,371,355 (+)EnsemblGRCm38mm10GRCm38
MGSCv37938,175,154 - 38,176,128 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera935,601,752 - 35,602,747 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14611657   PMID:15081110   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or8c10
44 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:72
Interacting mature miRNAs:72
Transcripts:ENSMUST00000052085
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
1301000Obq5_mobesity QTL 5 (mouse)Not determined92850333341799326Mouse
1301007Pid2_mprion incubation determinant 2 (mouse)Not determined93715336244251323Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
1558949Igan3_mIgA nephropathy 3 (mouse)Not determined93041469440565914Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
10045613Rapop7_mradiation-induced apoptosis 6 (mouse)Not determined93673624349420511Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1357682Phdlc1_mplasma HDL cholesterol 1 (mouse)Not determined93410461942764866Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
1301501Lmr2_mleishmaniasis resistance 2 (mouse)Not determined93694340650111140Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse

Markers in Region
UniSTS:489360  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38938,367,548 - 38,368,543UniSTSGRCm38
MGSCv37938,175,133 - 38,176,128UniSTSGRCm37
Celera935,601,752 - 35,602,747UniSTS
Cytogenetic Map9A5UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000052085   ⟹   ENSMUSP00000051631
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl938,278,844 - 38,279,839 (+)Ensembl
GRCm38.p6 Ensembl938,367,548 - 38,368,543 (+)Ensembl
Ensembl Acc Id: ENSMUST00000216168   ⟹   ENSMUSP00000150432
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl938,278,192 - 38,282,651 (+)Ensembl
GRCm38.p6 Ensembl938,366,896 - 38,371,355 (+)Ensembl
RefSeq Acc Id: NM_207552   ⟹   NP_997435
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39938,278,844 - 38,279,839 (+)NCBI
GRCm38938,367,548 - 38,368,543 (+)ENTREZGENE
MGSCv37938,175,154 - 38,176,128 (+)RGD
Celera935,601,752 - 35,602,747 (+)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_997435 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP70809 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000051631
  ENSMUSP00000051631.2
  ENSMUSP00000150432.2
RefSeq Acc Id: NP_997435   ⟸   NM_207552
- UniProtKB: E9PV37 (UniProtKB/TrEMBL),   Q7TS24 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000051631   ⟸   ENSMUST00000052085
Ensembl Acc Id: ENSMUSP00000150432   ⟸   ENSMUST00000216168
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PV37-F1-model_v2 AlphaFold E9PV37 1-331 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030084 AgrOrtholog
Ensembl Genes ENSMUSG00000049864 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000052085 ENTREZGENE
  ENSMUST00000052085.2 UniProtKB/TrEMBL
  ENSMUST00000216168.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:404312 UniProtKB/TrEMBL
MGD MGI:3030084 ENTREZGENE
NCBI Gene 404312 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or8c10 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A1L1STR2_MOUSE UniProtKB/TrEMBL
  E9PV37 ENTREZGENE, UniProtKB/TrEMBL
  Q7TS24 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or8c10  olfactory receptor family 8 subfamily C member 10  Olfr250  olfactory receptor 250  Symbol and/or name change 5135510 APPROVED