Mir199b (microRNA 199b) - Rat Genome Database

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Gene: Mir199b (microRNA 199b) Mus musculus
Analyze
Symbol: Mir199b
Name: microRNA 199b
RGD ID: 1607649
MGI Page MGI
Description: Acts upstream of or within cellular response to decreased oxygen levels and sensory perception of sound. Is expressed in brain meninges; embryo mesenchyme; and epithelium. Orthologous to human MIR199B (microRNA 199b).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-199b; Mirn1; Mirn199b
RGD Orthologs
Human
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,208,472 - 32,208,581 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,208,472 - 32,208,581 (+)EnsemblGRCm39 Ensembl
GRCm38232,318,460 - 32,318,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,318,460 - 32,318,569 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,173,980 - 32,174,089 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera232,023,513 - 32,023,622 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. miR-199b exerts tumor suppressive functions in hepatocellular carcinoma by directly targeting JAG1. Li GL, etal., Eur Rev Med Pharmacol Sci. 2018 Nov;22(22):7679-7687. doi: 10.26355/eurrev_201811_16388.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12554860   PMID:12624257   PMID:15634332   PMID:16381832   PMID:17369397   PMID:17604727   PMID:19147652   PMID:20215419   PMID:20413612   PMID:21037258   PMID:21102440   PMID:21267068  
PMID:21822254   PMID:23646144   PMID:25535084   PMID:26107383   PMID:29715263   PMID:30578296   PMID:32818586   PMID:33313638   PMID:34227902   PMID:34490833   PMID:35354755   PMID:38770735  
PMID:39177342  


Genomics

Comparative Map Data
Mir199b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,208,472 - 32,208,581 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,208,472 - 32,208,581 (+)EnsemblGRCm39 Ensembl
GRCm38232,318,460 - 32,318,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,318,460 - 32,318,569 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,173,980 - 32,174,089 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera232,023,513 - 32,023,622 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
MIR199B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,244,721 - 128,244,830 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,244,721 - 128,244,830 (-)EnsemblGRCh38hg38GRCh38
GRCh379131,007,000 - 131,007,109 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,046,820 - 130,046,929 (-)NCBINCBI36Build 36hg18NCBI36
Celera9101,657,904 - 101,658,013 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,620,454 - 100,620,563 (-)NCBIHuRef
CHM1_19131,158,023 - 131,158,132 (-)NCBICHM1_1
T2T-CHM13v2.09140,451,835 - 140,451,944 (-)NCBIT2T-CHM13v2.0
MIR199-3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,262,354 - 55,262,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,262,328 - 55,262,437 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,457,225 - 54,457,283 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,184,394 - 56,184,452 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1954,944,294 - 54,944,352 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,258,931 - 55,258,989 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,350,485 - 55,350,543 (+)NCBIUU_Cfam_GSD_1.0
MIR199B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,691,502 - 268,691,610 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,691,520 - 268,691,593 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,681,826 - 302,681,899 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir199b
2 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:21082
Count of gene targets:8898
Count of transcripts:14698
Interacting mature miRNAs:mmu-miR-199b-3p, mmu-miR-199b-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552706Cia24_mcollagen induced arthritis QTL 24 (mouse)Not determined22467911533523172Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
8552705Cia25_mcollagen induced arthritis 25 (mouse)Not determined22467911533523172Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000175066
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,208,472 - 32,208,581 (+)Ensembl
GRCm38.p6 Ensembl232,318,460 - 32,318,569 (+)Ensembl
RefSeq Acc Id: NR_029811
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39232,208,472 - 32,208,581 (+)NCBI
GRCm38232,318,460 - 32,318,569 (+)ENTREZGENE
MGSCv37232,173,980 - 32,174,089 (+)RGD
Celera232,023,513 - 32,023,622 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Promoters
RGD ID:6876988
Promoter ID:EPDNEW_M1945
Type:single initiation site
Name:Mir199b_1
Description:Mus musculus microRNA 199b , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38232,318,546 - 32,318,606EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676865 AgrOrtholog
Ensembl Genes ENSMUSG00000092807 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000175066 ENTREZGENE
MGD MGI:2676865 ENTREZGENE
miRBase MI0000714 ENTREZGENE
NCBI Gene 387239 ENTREZGENE
PhenoGen Mir199b PhenoGen
RNAcentral URS00003F2D94 RNACentral
  URS00004DECC9 RNACentral
  URS000075997E RNACentral