TMEM97 (transmembrane protein 97) - Rat Genome Database

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Gene: TMEM97 (transmembrane protein 97) Homo sapiens
Analyze
Symbol: TMEM97
Name: transmembrane protein 97
RGD ID: 1607046
HGNC Page HGNC:28106
Description: Predicted to enable cholesterol binding activity and oxysterol binding activity. Involved in several processes, including cholesterol homeostasis; positive regulation of lipoprotein transport; and regulation of intracellular cholesterol transport. Located in several cellular components, including lysosome; nuclear membrane; and rough endoplasmic reticulum. Is active in endoplasmic reticulum.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MAC30; meningioma-associated protein 30; S2R; sigma intracellular receptor 2; sigma-2 receptor; sigma2 receptor; sigma2R
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: TMEM97P1   TMEM97P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,319,200 - 28,328,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,319,200 - 28,328,685 (+)EnsemblGRCh38hg38GRCh38
GRCh371726,646,226 - 26,655,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,670,248 - 23,679,838 (+)NCBINCBI36Build 36hg18NCBI36
Celera1723,507,857 - 23,517,453 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1722,854,509 - 22,864,105 (+)NCBIHuRef
CHM1_11726,709,006 - 26,718,604 (+)NCBICHM1_1
T2T-CHM13v2.01729,261,048 - 29,270,533 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 165 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TMEM97Human(-)-alpha-phellandrene decreases expressionEXP 6480464alpha phellandrene results in decreased expression of TMEM97 mRNACTDPMID:25075043
TMEM97Human(-)-epigallocatechin 3-gallate increases expressionEXP 6480464epigallocatechin gallate results in increased expression of TMEM97 mRNACTDPMID:32512070
TMEM97Human(1->4)-beta-D-glucan multiple interactionsISORGD:13166126480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM97 mRNACTDPMID:36331819
TMEM97Human(S)-nicotine increases expressionISORGD:13166126480464Nicotine results in increased expression of TMEM97 mRNACTDPMID:17997037
TMEM97Human1,2-dichloroethane decreases expressionISORGD:13166126480464ethylene dichloride results in decreased expression of TMEM97 mRNACTDPMID:28189721|PMID:28960355
TMEM97Human1,2-dimethylhydrazine multiple interactionsISORGD:13166126480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TMEM97 mRNACTDPMID:22206623
TMEM97Human1-naphthyl isothiocyanate increases expressionISORGD:130742364804641-Naphthylisothiocyanate results in increased expression of TMEM97 mRNACTDPMID:30723492
TMEM97Human17alpha-ethynylestradiol affects expressionISORGD:13074236480464Ethinyl Estradiol affects the expression of TMEM97 mRNACTDPMID:17351261
TMEM97Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of TMEM97 mRNACTDPMID:16474171|PMID:19167446
TMEM97Human17beta-estradiol increases expressionISORGD:13166126480464Estradiol results in increased expression of TMEM97 mRNACTDPMID:39298647
TMEM97Human17beta-estradiol affects expressionISORGD:13074236480464Estradiol affects the expression of TMEM97 mRNACTDPMID:32145629
TMEM97Human2,3',4,4',5-Pentachlorobiphenyl increases expressionISORGD:131661264804642,3',4,4',5-pentachlorobiphenyl results in increased expression of TMEM97 mRNACTDPMID:31388691
TMEM97Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13166126480464Tetrachlorodibenzodioxin results in increased expression of TMEM97 mRNACTDPMID:19933214
TMEM97Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13074236480464Tetrachlorodibenzodioxin results in increased expression of TMEM97 mRNACTDPMID:34747641
TMEM97Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:13074236480464Tetrachlorodibenzodioxin results in decreased expression of TMEM97 mRNACTDPMID:32109520
TMEM97Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of TMEM97 mRNACTDPMID:20106945|PMID:21632981|PMID:26238291
TMEM97Human2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of TMEM97 mRNACTDPMID:22574217
TMEM97Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13166126480464Tetrachlorodibenzodioxin affects the expression of TMEM97 mRNACTDPMID:21570461
TMEM97Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:13166126480464Tetrachlorodibenzodioxin results in decreased expression of TMEM97 mRNACTDPMID:20159946
TMEM97Human2,4,6-trinitrotoluene affects expressionISORGD:13074236480464Trinitrotoluene affects the expression of TMEM97 mRNACTDPMID:21346803

1 to 20 of 165 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TMEM97Humancholesterol homeostasis involved_inIDA 150520179 PMID:19583955UniProtPMID:19583955
TMEM97Humanpositive regulation of lipoprotein transport involved_inIMP 150520179 PMID:30443021UniProtPMID:30443021
TMEM97Humanpositive regulation of wound healing involved_inIMP 150520179 PMID:34233061UniProtPMID:34233061
TMEM97Humanregulation of cell growth involved_inNAS 150520179 PMID:7694637UniProtPMID:7694637
TMEM97Humanregulation of intracellular cholesterol transport involved_inIMP 150520179 PMID:27378690UniProtPMID:27378690
TMEM97Humanregulation of intracellular lipid transport involved_inIMP 150520179 PMID:27378690UniProtPMID:27378690

Cellular Component
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TMEM97Humanendoplasmic reticulum is_active_inIDA 150520179 PMID:34233061UniProtPMID:34233061
TMEM97Humanendoplasmic reticulum located_inIDA 150520179 HPAGO_REF:0000052
TMEM97Humanendoplasmic reticulum located_inIEAUniProtKB-KW:KW-0256150520179 UniProtGO_REF:0000043
TMEM97Humanendoplasmic reticulum is_active_inIBAPANTHER:PTN001260854|UniProtKB:Q5BJF2150520179 GO_CentralGO_REF:0000033
TMEM97Humanlysosome located_inIDA 150520179 PMID:19583955UniProtPMID:19583955
TMEM97Humanmembrane located_inIEAUniRule:UR000414115150520179 UniProtGO_REF:0000104
TMEM97Humanmembrane located_inIEAUniProtKB-SubCell:SL-0162150520179 UniProtGO_REF:0000044
TMEM97Humanmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
TMEM97Humannuclear membrane located_inIDA 150520179 PMID:19583955UniProtPMID:19583955
TMEM97Humannuclear membrane located_inIEAUniProtKB-SubCell:SL-0182150520179 UniProtGO_REF:0000044
TMEM97Humannucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
TMEM97Humanplasma membrane located_inIDA 150520179 PMID:19583955UniProtPMID:19583955
TMEM97Humanrough endoplasmic reticulum located_inIDA 150520179 PMID:19583955UniProtPMID:19583955
TMEM97Humanrough endoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-0237150520179 UniProtGO_REF:0000044
1 to 14 of 14 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TMEM97Humancholesterol binding enablesISSUniProtKB:Q3MHW7150520179 UniProtGO_REF:0000024
TMEM97Humanoxysterol binding enablesIEAUniProtKB:Q8VD00|ensembl:ENSMUSP00000099532150520179 EnsemblGO_REF:0000107
TMEM97Humanoxysterol binding enablesISSUniProtKB:Q8VD00150520179 UniProtGO_REF:0000024
TMEM97Humanprotein binding enablesIPIUniProtKB:P15515150520179 PMID:34233061UniProtPMID:34233061
TMEM97Humanprotein binding enablesIPIUniProtKB:O00264|UniProtKB:P30536150520179 PMID:37047353UniProtPMID:37047353
TMEM97Humanprotein binding enablesIPIUniProtKB:O00264|UniProtKB:P01130150520179 PMID:30443021UniProtPMID:30443021
TMEM97Humanprotein binding enablesIPIUniProtKB:O15118150520179 PMID:19583955, PMID:34799735UniProtPMID:19583955|PMID:34799735
TMEM97Humanprotein binding enablesIPIUniProtKB:A2A2Y4|UniProtKB:A6NM10-2|UniProtKB:A8MZ59|UniProtKB:O14524-2|UniProtKB:O15552|UniProtKB:O43278-2|UniProtKB:O60883|UniProtKB:O75712|UniProtKB:O75787|UniProtKB:O95377|UniProtKB:O95470|UniProtKB:O95471|UniProtKB:P04233-2|UniProtKB:P15941-11|UniProtKB:P19397|UniProtKB:P38484|UniProtKB:P41181|UniProtKB:P43628|UniProtKB:P60201-2|UniProtKB:Q13113|UniProtKB:Q13323|UniProtKB:Q13336-2|UniProtKB:Q13520|UniProtKB:Q14802-3|UniProtKB:Q15125|UniProtKB:Q15849|UniProtKB:Q3SXY8|UniProtKB:Q4KMG9|UniProtKB:Q5JX71|UniProtKB:Q6IN84|UniProtKB:Q7Z5P4|UniProtKB:Q7Z7G2|UniProtKB:Q8N183|UniProtKB:Q8TAF8|UniProtKB:Q8TDT2|UniProtKB:Q8TED1|UniProtKB:Q8WWF3|UniProtKB:Q8WWH4|UniProtKB:Q96AG4|UniProtKB:Q96B21|UniProtKB:Q96K19-5|UniProtKB:Q99675|UniProtKB:Q9BQ51|UniProtKB:Q9BQT9|UniProtKB:Q9BSE2|UniProtKB:Q9BVX2|UniProtKB:Q9BXK5|UniProtKB:Q9GZY8-5|UniProtKB:Q9H2K0|UniProtKB:Q9H400|UniProtKB:Q9H7M9|UniProtKB:Q9H902|UniProtKB:Q9NR31|UniProtKB:Q9NUH8|UniProtKB:Q9UBD6|UniProtKB:Q9Y282|UniProtKB:Q9Y320|UniProtKB:Q9Y375|UniProtKB:Q9Y680150520179 PMID:32296183IntActPMID:32296183


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:7694637   PMID:12477932   PMID:15375745   PMID:15489334   PMID:16344560   PMID:17143516   PMID:18029348   PMID:18070364   PMID:19322201   PMID:19583955   PMID:21079401   PMID:21832049  
PMID:21873635   PMID:22024687   PMID:23229099   PMID:23254963   PMID:24797263   PMID:24853233   PMID:25080503   PMID:25959826   PMID:26002575   PMID:26186194   PMID:27268655   PMID:27378690  
PMID:27432908   PMID:27688262   PMID:28514442   PMID:28559337   PMID:28644012   PMID:28972404   PMID:29180619   PMID:29599847   PMID:30443021   PMID:30639242   PMID:31586073   PMID:31678930  
PMID:32296183   PMID:32572762   PMID:32628020   PMID:33618021   PMID:33961781   PMID:34079125   PMID:34233061   PMID:34615853   PMID:34799735   PMID:35373413   PMID:35906200   PMID:35907137  
PMID:35970844   PMID:36215168   PMID:36244648   PMID:36949045   PMID:37047353   PMID:37314216   PMID:37827155   PMID:38113892   PMID:38319380   PMID:38388887   PMID:39468006  



TMEM97
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,319,200 - 28,328,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,319,200 - 28,328,685 (+)EnsemblGRCh38hg38GRCh38
GRCh371726,646,226 - 26,655,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,670,248 - 23,679,838 (+)NCBINCBI36Build 36hg18NCBI36
Celera1723,507,857 - 23,517,453 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1722,854,509 - 22,864,105 (+)NCBIHuRef
CHM1_11726,709,006 - 26,718,604 (+)NCBICHM1_1
T2T-CHM13v2.01729,261,048 - 29,270,533 (+)NCBIT2T-CHM13v2.0
Tmem97
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,432,643 - 78,441,561 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,432,643 - 78,441,603 (-)EnsemblGRCm39 Ensembl
GRCm381178,541,817 - 78,550,735 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,541,817 - 78,550,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv371178,355,319 - 78,364,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361178,358,012 - 78,366,930 (-)NCBIMGSCv36mm8
Celera1188,173,890 - 88,182,808 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
Tmem97
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,936,276 - 63,945,359 (-)NCBIGRCr8
mRatBN7.21063,438,228 - 63,447,311 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1063,438,222 - 63,589,730 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1068,070,852 - 68,079,944 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,576,183 - 67,585,275 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01063,045,738 - 63,054,825 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,811,455 - 65,820,538 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,811,456 - 65,820,538 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01065,823,082 - 65,832,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,652,641 - 64,661,724 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11064,666,264 - 64,675,347 (-)NCBI
Celera1062,414,772 - 62,423,855 (-)NCBICelera
Cytogenetic Map10q25NCBI
Tmem97
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,807,850 - 4,817,006 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,807,850 - 4,817,006 (-)NCBIChiLan1.0ChiLan1.0
TMEM97
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21936,130,408 - 36,140,584 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11738,010,800 - 38,020,975 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01728,446,213 - 28,455,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11728,948,225 - 28,957,345 (-)NCBIpanpan1.1PanPan1.1panPan2
TMEM97
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,572,855 - 42,581,012 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,572,889 - 42,579,947 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,729,777 - 41,737,940 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0943,391,799 - 43,400,150 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,391,761 - 43,400,631 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,176,287 - 42,184,423 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,467,497 - 42,475,646 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,544,521 - 42,552,694 (+)NCBIUU_Cfam_GSD_1.0
Tmem97
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,597,080 - 41,606,883 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365384,475,256 - 4,484,643 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365384,475,314 - 4,484,385 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM97
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,604,021 - 44,609,999 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11244,603,764 - 44,609,935 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TMEM97
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,044,208 - 22,092,969 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660758,035,869 - 8,043,735 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem97
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624786915,640 - 928,022 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624786915,839 - 928,022 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in TMEM97
11 total Variants

1 to 10 of 24 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 17q11.2(chr17:28283125-28904397)x3 copy number gain See cases [RCV000136494] Chr17:28283125..28904397 [GRCh38]
Chr17:26610151..27231415 [GRCh37]
Chr17:23634278..24255541 [NCBI36]
Chr17:17q11.2
benign
GRCh37/hg19 17q11.1-11.2(chr17:25403446-31685464)x3 copy number gain not provided [RCV000762776] Chr17:25403446..31685464 [GRCh37]
Chr17:17q11.1-11.2
likely pathogenic
GRCh37/hg19 17p11.2-q11.2(chr17:21308559-26655801)x3 copy number gain See cases [RCV000240004] Chr17:21308559..26655801 [GRCh37]
Chr17:17p11.2-q11.2
uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q11.1-11.2(chr17:25248166-30645676)x1 copy number loss Mitogen-activated protein kinase kinase inhibitor response [RCV000626439] Chr17:25248166..30645676 [GRCh37]
Chr17:17q11.1-11.2
drug response
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p11.2-q11.2(chr17:21279289-27474974)x2 copy number gain not provided [RCV000739439] Chr17:21279289..27474974 [GRCh37]
Chr17:17p11.2-q11.2
likely pathogenic
1 to 10 of 24 rows

Predicted Target Of
Summary Value
Count of predictions:2042
Count of miRNA genes:783
Interacting mature miRNAs:877
Transcripts:ENST00000226230, ENST00000336687, ENST00000582113, ENST00000582384, ENST00000583381
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 19 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597091411GWAS1187485_Hatrophic macular degeneration, age-related macular degeneration, wet macular degeneration QTL GWAS1187485 (human)1e-08atrophic macular degeneration, age-related macular degeneration, wet macular degeneration172832269828322699Human
597122322GWAS1218396_Hblood protein measurement QTL GWAS1218396 (human)9e-29blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)172832269828322699Human
597275326GWAS1371400_Hage-related macular degeneration, COVID-19 QTL GWAS1371400 (human)3e-09age-related macular degeneration, COVID-19172832269828322699Human
597301363GWAS1397437_HPAX-interacting protein 1 measurement QTL GWAS1397437 (human)4e-12PAX-interacting protein 1 measurement172832269828322699Human
597172369GWAS1268443_Hpoly(A) RNA polymerase, mitochondrial measurement QTL GWAS1268443 (human)2e-17poly(A) RNA polymerase, mitochondrial measurement172832269828322699Human
597143518GWAS1239592_Hlow density lipoprotein cholesterol measurement QTL GWAS1239592 (human)5e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)172832618128326182Human
597121693GWAS1217767_Hblood protein measurement QTL GWAS1217767 (human)1e-12blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)172832269828322699Human
597123419GWAS1219493_Hblood protein measurement QTL GWAS1219493 (human)1e-14blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)172832269828322699Human
597235540GWAS1331614_Hblood protein measurement QTL GWAS1331614 (human)3e-31blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)172832269828322699Human
597172790GWAS1268864_Hcarboxypeptidase Z measurement QTL GWAS1268864 (human)4e-15carboxypeptidase Z measurement172832269828322699Human

1 to 10 of 19 rows
SHGC-11786  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,655,146 - 26,655,232UniSTSGRCh37
Build 361723,679,273 - 23,679,359RGDNCBI36
Celera1723,516,888 - 23,516,974RGD
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map17q11.2UniSTS
HuRef819,331,779 - 19,331,848UniSTS
GeneMap99-G3 RH Map171526.0UniSTS
RH17628  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,655,050 - 26,655,209UniSTSGRCh37
Build 361723,679,177 - 23,679,336RGDNCBI36
Celera1723,516,792 - 23,516,951RGD
Cytogenetic Map17q11.2UniSTS
HuRef1722,863,444 - 22,863,603UniSTS
RH24980  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,655,433 - 26,655,644UniSTSGRCh37
Build 361723,679,560 - 23,679,771RGDNCBI36
Celera1723,517,175 - 23,517,386RGD
Cytogenetic Map17q11.2UniSTS
HuRef1722,863,827 - 22,864,038UniSTS
SHGC-132058  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,655,369 - 26,655,687UniSTSGRCh37
Build 361723,679,496 - 23,679,814RGDNCBI36
Celera1723,517,111 - 23,517,429RGD
Cytogenetic Map17q11.2UniSTS
HuRef1722,863,763 - 22,864,081UniSTS
TNG Radiation Hybrid Map1710748.0UniSTS
UniSTS:21338  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,655,372 - 26,655,588UniSTSGRCh37
Build 361723,679,499 - 23,679,715RGDNCBI36
Celera1723,517,114 - 23,517,330RGD
HuRef1722,863,766 - 22,863,982UniSTS
D20S1105  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,655,352 - 26,655,584UniSTSGRCh37
Build 361723,679,479 - 23,679,711RGDNCBI36
Celera1723,517,094 - 23,517,326RGD
Cytogenetic Map17q11.2UniSTS
HuRef1722,863,746 - 22,863,978UniSTS
Stanford-G3 RH Map171023.0UniSTS
GeneMap99-G3 RH Map171524.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2249 4969 1726 2351 5 624 1948 465 2268 7297 6463 53 3732 1 850 1740 1617 175 1



Ensembl Acc Id: ENST00000226230   ⟹   ENSP00000226230
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,319,200 - 28,328,685 (+)Ensembl
Ensembl Acc Id: ENST00000336687   ⟹   ENSP00000466987
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,319,455 - 28,328,225 (+)Ensembl
Ensembl Acc Id: ENST00000582113   ⟹   ENSP00000462827
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,319,206 - 28,325,835 (+)Ensembl
Ensembl Acc Id: ENST00000582384   ⟹   ENSP00000462924
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,319,269 - 28,327,511 (+)Ensembl
Ensembl Acc Id: ENST00000583381   ⟹   ENSP00000466211
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,319,202 - 28,326,875 (+)Ensembl
RefSeq Acc Id: NM_014573   ⟹   NP_055388
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,319,200 - 28,328,685 (+)NCBI
GRCh371726,646,121 - 26,655,711 (+)RGD
Build 361723,670,248 - 23,679,838 (+)NCBI Archive
Celera1723,507,857 - 23,517,453 (+)RGD
HuRef1722,854,509 - 22,864,105 (+)ENTREZGENE
CHM1_11726,709,006 - 26,718,604 (+)NCBI
T2T-CHM13v2.01729,261,048 - 29,270,533 (+)NCBI
Sequence:
1 to 12 of 12 rows
Protein RefSeqs NP_055388 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16188 (Get FASTA)   NCBI Sequence Viewer  
  AAH45655 (Get FASTA)   NCBI Sequence Viewer  
  AAH91504 (Get FASTA)   NCBI Sequence Viewer  
  BAG56847 (Get FASTA)   NCBI Sequence Viewer  
  BAG61464 (Get FASTA)   NCBI Sequence Viewer  
  EAW51067 (Get FASTA)   NCBI Sequence Viewer  
  EAW51068 (Get FASTA)   NCBI Sequence Viewer  
  EAW51069 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000226230
  ENSP00000226230.6
GenBank Protein Q5BJF2 (Get FASTA)   NCBI Sequence Viewer  
1 to 12 of 12 rows
RefSeq Acc Id: NP_055388   ⟸   NM_014573
- UniProtKB: B4DS02 (UniProtKB/Swiss-Prot),   Q07823 (UniProtKB/Swiss-Prot),   Q5BJF2 (UniProtKB/Swiss-Prot),   B4DDT6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000462924   ⟸   ENST00000582384
Ensembl Acc Id: ENSP00000462827   ⟸   ENST00000582113
Ensembl Acc Id: ENSP00000466211   ⟸   ENST00000583381
Ensembl Acc Id: ENSP00000466987   ⟸   ENST00000336687
EXPERA

Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJF2-F1-model_v2 AlphaFold Q5BJF2 1-176 view protein structure

RGD ID:6794632
Promoter ID:HG_KWN:25534
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_014573
Position:
Human AssemblyChrPosition (strand)Source
Build 361723,669,851 - 23,670,351 (+)MPROMDB
RGD ID:7234339
Promoter ID:EPDNEW_H22915
Type:initiation region
Name:TMEM97_1
Description:transmembrane protein 97
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,319,200 - 28,319,260EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
COSMIC TMEM97 COSMIC
Ensembl Genes ENSG00000109084 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000226230 ENTREZGENE
  ENST00000226230.8 UniProtKB/Swiss-Prot
GTEx ENSG00000109084 GTEx
HGNC ID HGNC:28106 ENTREZGENE
Human Proteome Map TMEM97 Human Proteome Map
InterPro EXPERA UniProtKB/Swiss-Prot
  Sigma-2_receptor-like UniProtKB/Swiss-Prot
  Sigma2_recept UniProtKB/Swiss-Prot
KEGG Report hsa:27346 UniProtKB/Swiss-Prot
NCBI Gene 27346 ENTREZGENE
OMIM 612912 OMIM
PANTHER SIGMA INTRACELLULAR RECEPTOR 2 UniProtKB/Swiss-Prot
  SIGMA INTRACELLULAR RECEPTOR 2 UniProtKB/Swiss-Prot
Pfam EBP UniProtKB/Swiss-Prot
PharmGKB PA143485635 PharmGKB
PIRSF TMP_97_prd UniProtKB/Swiss-Prot
PROSITE EXPERA UniProtKB/Swiss-Prot
UniProt B4DDT6 ENTREZGENE, UniProtKB/TrEMBL
  B4DS02 ENTREZGENE
  J3KT68_HUMAN UniProtKB/TrEMBL
  J3KTD1_HUMAN UniProtKB/TrEMBL
  Q07823 ENTREZGENE
  Q5BJF2 ENTREZGENE
  Q86XC5_HUMAN UniProtKB/TrEMBL
  SGMR2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B4DS02 UniProtKB/Swiss-Prot
  Q07823 UniProtKB/Swiss-Prot
1 to 29 of 29 rows