NBPF2P (NBPF member 2, pseudogene) - Rat Genome Database

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Gene: NBPF2P (NBPF member 2, pseudogene) Homo sapiens
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Symbol: NBPF2P
Name: NBPF member 2, pseudogene
RGD ID: 1606651
HGNC Page HGNC:31987
Description: This pseudogene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Apr 2013]
Type: pseudo (Ensembl: unprocessed_pseudogene)
RefSeq Status: REVIEWED
Previously known as: neuroblastoma breakpoint family member 2, pseudogene
Related Functional Gene: NBPF3  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38121,423,108 - 21,427,960 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl121,424,625 - 21,427,967 (-)EnsemblGRCh38hg38GRCh38
GRCh37121,749,601 - 21,754,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36121,622,088 - 21,627,140 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map1p36.12NCBI
HuRef119,993,526 - 19,998,375 (-)NCBIHuRef
CHM1_1121,861,597 - 21,866,447 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16079250   PMID:22973535  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:402
Count of miRNA genes:265
Interacting mature miRNAs:275
Transcripts:ENST00000426482, ENST00000453025
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 11 2 7 1 2 66 1
Low 1933 1023 1218 215 625 87 2597 843 2266 272 1203 1211 137 858 1377 4
Below cutoff 414 1630 393 320 735 293 1393 1048 1302 111 138 319 29 314 1097

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_005533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL592309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000453025
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl121,424,625 - 21,427,967 (-)Ensembl

Additional Information

Database Acc Id Source(s)
COSMIC NBPF2P COSMIC
Ensembl Genes ENSG00000227001 Ensembl
GTEx ENSG00000227001 GTEx
HGNC ID HGNC:31987 ENTREZGENE
Human Proteome Map NBPF2P Human Proteome Map
NCBI Gene 343381 ENTREZGENE
PharmGKB PA142671282 PharmGKB


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-07 NBPF2P  NBPF member 2, pseudogene    neuroblastoma breakpoint family member 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2015-11-24 NBPF2P  neuroblastoma breakpoint family member 2, pseudogene    neuroblastoma breakpoint family, member 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2011-07-27 NBPF2P  neuroblastoma breakpoint family, member 2, pseudogene  NBPF2P  neuroblastoma breakpoint family, member 2 (pseudogene)  Symbol and/or name change 5135510 APPROVED