AMMECR1L (AMMECR1 like) - Rat Genome Database

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Gene: AMMECR1L (AMMECR1 like) Homo sapiens
Analyze
Symbol: AMMECR1L
Name: AMMECR1 like
RGD ID: 1605931
HGNC Page HGNC:28658
Description: Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AMME chromosomal region gene 1-like; AMMECR1-like; AMMECR1-like protein; FLJ38552; MGC4268
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: AMMECR1LP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382127,861,630 - 127,885,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2127,861,630 - 127,885,967 (-)EnsemblGRCh38hg38GRCh38
GRCh372128,619,204 - 128,643,530 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362128,335,674 - 128,358,904 (-)NCBINCBI36Build 36hg18NCBI36
Celera2121,930,156 - 121,953,388 (-)NCBICelera
Cytogenetic Map2q14.3NCBI
HuRef2120,925,501 - 120,949,646 (-)NCBIHuRef
CHM1_12128,624,214 - 128,648,542 (-)NCBICHM1_1
T2T-CHM13v2.02128,296,887 - 128,321,215 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334   PMID:17207965   PMID:19322201   PMID:20098747   PMID:21873635   PMID:22087225   PMID:23602568   PMID:26186194   PMID:27432908   PMID:28514442  
PMID:29193635   PMID:30021884   PMID:33961781   PMID:34315543   PMID:35563538  


Genomics

Comparative Map Data
AMMECR1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382127,861,630 - 127,885,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2127,861,630 - 127,885,967 (-)EnsemblGRCh38hg38GRCh38
GRCh372128,619,204 - 128,643,530 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362128,335,674 - 128,358,904 (-)NCBINCBI36Build 36hg18NCBI36
Celera2121,930,156 - 121,953,388 (-)NCBICelera
Cytogenetic Map2q14.3NCBI
HuRef2120,925,501 - 120,949,646 (-)NCBIHuRef
CHM1_12128,624,214 - 128,648,542 (-)NCBICHM1_1
T2T-CHM13v2.02128,296,887 - 128,321,215 (-)NCBIT2T-CHM13v2.0
Ammecr1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391831,891,457 - 31,917,136 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1831,892,879 - 31,915,796 (+)EnsemblGRCm39 Ensembl
GRCm381831,758,504 - 31,784,083 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1831,759,826 - 31,782,743 (+)EnsemblGRCm38mm10GRCm38
MGSCv371831,919,534 - 31,942,397 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361831,902,890 - 31,925,753 (+)NCBIMGSCv36mm8
Celera1832,247,440 - 32,270,246 (+)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1817.84NCBI
Ammecr1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81823,661,649 - 23,685,391 (+)NCBIGRCr8
mRatBN7.21823,386,114 - 23,411,177 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1823,386,903 - 23,410,920 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1823,516,338 - 23,539,255 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01824,265,365 - 24,288,279 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01823,611,305 - 23,634,222 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01824,539,530 - 24,563,576 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1824,540,659 - 24,563,576 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01824,256,630 - 24,281,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41824,175,222 - 24,198,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11824,201,417 - 24,223,692 (+)NCBI
Celera1823,140,658 - 23,163,573 (+)NCBICelera
Cytogenetic Map18p12NCBI
Ammecr1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554592,654,361 - 2,678,080 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554592,654,361 - 2,678,080 (+)NCBIChiLan1.0ChiLan1.0
AMMECR1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21347,759,074 - 47,783,757 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B47,774,318 - 47,812,676 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B32,391,258 - 32,415,660 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B128,526,664 - 128,549,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B128,526,669 - 128,549,436 (-)Ensemblpanpan1.1panPan2
AMMECR1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11922,715,611 - 22,747,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1922,726,419 - 22,744,432 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1922,962,782 - 22,995,123 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01924,041,709 - 24,074,486 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1924,051,437 - 24,074,484 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11922,696,659 - 22,729,413 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01922,940,809 - 22,973,124 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01924,071,887 - 24,104,696 (+)NCBIUU_Cfam_GSD_1.0
Ammecr1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530398,146,540 - 98,170,991 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646943,445,725 - 43,471,226 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646943,445,707 - 43,471,170 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMMECR1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1559,453,722 - 59,476,517 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11559,453,070 - 59,476,526 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21566,209,522 - 66,238,678 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AMMECR1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1102,330,828 - 2,358,239 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl102,335,031 - 2,358,391 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606120,404,483 - 20,429,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ammecr1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473214,313,808 - 14,339,847 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473214,314,257 - 14,339,942 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AMMECR1L
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q14.3-21.1(chr2:127440559-129427805)x3 copy number gain See cases [RCV000052948] Chr2:127440559..129427805 [GRCh38]
Chr2:128198135..130185378 [GRCh37]
Chr2:127914605..129901848 [NCBI36]
Chr2:2q14.3-21.1		 pathogenic
GRCh38/hg38 2q14.1-21.3(chr2:118086324-134964738)x1 copy number loss See cases [RCV000054058] Chr2:118086324..134964738 [GRCh38]
Chr2:118843900..135722308 [GRCh37]
Chr2:118560370..135438778 [NCBI36]
Chr2:2q14.1-21.3		 pathogenic
GRCh38/hg38 2q14.3(chr2:121824798-128870804)x1 copy number loss See cases [RCV000054059] Chr2:121824798..128870804 [GRCh38]
Chr2:122582374..129628378 [GRCh37]
Chr2:122298844..129344848 [NCBI36]
Chr2:2q14.3		 pathogenic
GRCh38/hg38 2q14.3(chr2:122324343-128371704)x1 copy number loss See cases [RCV000054060] Chr2:122324343..128371704 [GRCh38]
Chr2:123081919..129129278 [GRCh37]
Chr2:122798389..128845748 [NCBI36]
Chr2:2q14.3		 pathogenic
NM_001199140.1(AMMECR1L):c.543C>T (p.Pro181=) single nucleotide variant Malignant melanoma [RCV000065052] Chr2:127870904 [GRCh38]
Chr2:128628478 [GRCh37]
Chr2:128344948 [NCBI36]
Chr2:2q14.3		 not provided
GRCh38/hg38 2q14.3(chr2:123169989-128460075)x1 copy number loss See cases [RCV000135455] Chr2:123169989..128460075 [GRCh38]
Chr2:123927565..129217649 [GRCh37]
Chr2:123644035..128934119 [NCBI36]
Chr2:2q14.3		 pathogenic
GRCh38/hg38 2q14.3-22.1(chr2:123445762-140592538)x1 copy number loss See cases [RCV000136714] Chr2:123445762..140592538 [GRCh38]
Chr2:124203338..141350107 [GRCh37]
Chr2:123919808..141066577 [NCBI36]
Chr2:2q14.3-22.1		 pathogenic
GRCh38/hg38 2q14.3-21.1(chr2:122847356-129545581)x1 copy number loss See cases [RCV000137467] Chr2:122847356..129545581 [GRCh38]
Chr2:123604932..130303154 [GRCh37]
Chr2:123321402..130019624 [NCBI36]
Chr2:2q14.3-21.1		 likely pathogenic
GRCh38/hg38 2q14.3-21.1(chr2:127063206-130527454)x3 copy number gain See cases [RCV000138369] Chr2:127063206..130527454 [GRCh38]
Chr2:127820782..131285027 [GRCh37]
Chr2:127537252..131001497 [NCBI36]
Chr2:2q14.3-21.1		 uncertain significance
GRCh38/hg38 2q14.1-14.3(chr2:115302067-129071130)x1 copy number loss See cases [RCV000141584] Chr2:115302067..129071130 [GRCh38]
Chr2:116059643..129828703 [GRCh37]
Chr2:115776113..129545173 [NCBI36]
Chr2:2q14.1-14.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q14.3-22.1(chr2:128490257-138210164)x1 copy number loss See cases [RCV000445892] Chr2:128490257..138210164 [GRCh37]
Chr2:2q14.3-22.1		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q12.1-24.3(chr2:104172062-168223828)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626436] Chr2:104172062..168223828 [GRCh37]
Chr2:2q12.1-24.3		 drug response
GRCh37/hg19 2q14.2-22.1(chr2:120571363-141627287)x1 copy number loss See cases [RCV000512348] Chr2:120571363..141627287 [GRCh37]
Chr2:2q14.2-22.1		 pathogenic
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3		 likely pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NC_000002.12:g.124348648_129410245del deletion See cases [RCV001568390] Chr2:124348648..129410245 [GRCh38]
Chr2:2q14.3-21.1		 not provided
NM_001199140.2(AMMECR1L):c.244G>C (p.Ala82Pro) single nucleotide variant not provided [RCV000948607] Chr2:127873991 [GRCh38]
Chr2:128631565 [GRCh37]
Chr2:2q14.3		 benign
GRCh37/hg19 2q14.3-21.2(chr2:122952356-133826358)x1 copy number loss See cases [RCV001194541] Chr2:122952356..133826358 [GRCh37]
Chr2:2q14.3-21.2		 likely pathogenic
GRCh37/hg19 2q14.3(chr2:128494642-128910835)x3 copy number gain not provided [RCV001005315] Chr2:128494642..128910835 [GRCh37]
Chr2:2q14.3		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q13-22.3(chr2:111484468-146333604)x3 copy number gain not provided [RCV001832896] Chr2:111484468..146333604 [GRCh37]
Chr2:2q13-22.3		 pathogenic
GRCh37/hg19 2q14.3-22.2(chr2:122699106-143799629)x1 copy number loss not provided [RCV001832883] Chr2:122699106..143799629 [GRCh37]
Chr2:2q14.3-22.2		 pathogenic
GRCh37/hg19 2q14.3(chr2:128024782-129332242) copy number gain not specified [RCV002053228] Chr2:128024782..129332242 [GRCh37]
Chr2:2q14.3		 uncertain significance
GRCh37/hg19 2q13-22.3(chr2:112475655-145691999)x3 copy number gain 2q13q22.3 microduplication syndrome [RCV002226436] Chr2:112475655..145691999 [GRCh37]
Chr2:2q13-22.3		 pathogenic
NC_000002.11:g.(?_127806102)_(129076137_?)del deletion Thrombophilia due to protein C deficiency, autosomal dominant [RCV003110990] Chr2:127806102..129076137 [GRCh37]
Chr2:2q14.3		 pathogenic
NC_000002.11:g.(?_127451420)_(129076137_?)del deletion not provided [RCV003119332] Chr2:127451420..129076137 [GRCh37]
Chr2:2q14.3		 pathogenic
NM_001199140.2(AMMECR1L):c.725A>G (p.Asp242Gly) single nucleotide variant not specified [RCV004244230] Chr2:127866996 [GRCh38]
Chr2:128624570 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.242C>T (p.Pro81Leu) single nucleotide variant not specified [RCV004152116] Chr2:127873993 [GRCh38]
Chr2:128631567 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.445C>T (p.Arg149Trp) single nucleotide variant not specified [RCV004119342] Chr2:127871322 [GRCh38]
Chr2:128628896 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.380G>A (p.Arg127Gln) single nucleotide variant not specified [RCV004117507] Chr2:127873855 [GRCh38]
Chr2:128631429 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.74A>G (p.Lys25Arg) single nucleotide variant not specified [RCV004159878] Chr2:127874161 [GRCh38]
Chr2:128631735 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.229A>T (p.Thr77Ser) single nucleotide variant not specified [RCV004091483] Chr2:127874006 [GRCh38]
Chr2:128631580 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.479T>C (p.Met160Thr) single nucleotide variant not specified [RCV004324419] Chr2:127871288 [GRCh38]
Chr2:128628862 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.272G>A (p.Arg91Gln) single nucleotide variant not specified [RCV004344822] Chr2:127873963 [GRCh38]
Chr2:128631537 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.858G>T (p.Glu286Asp) single nucleotide variant not specified [RCV004348868] Chr2:127865169 [GRCh38]
Chr2:128622743 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.891C>T (p.Asn297=) single nucleotide variant not provided [RCV003429266] Chr2:127865136 [GRCh38]
Chr2:128622710 [GRCh37]
Chr2:2q14.3		 likely benign
GRCh37/hg19 2q14.3(chr2:124806439-128906413)x1 copy number loss not provided [RCV003484871] Chr2:124806439..128906413 [GRCh37]
Chr2:2q14.3		 uncertain significance
GRCh37/hg19 2q14.3(chr2:125361063-129616153)x3 copy number gain not specified [RCV003986353] Chr2:125361063..129616153 [GRCh37]
Chr2:2q14.3		 uncertain significance
GRCh37/hg19 2q12.2-21.2(chr2:106755586-134302739)x1 copy number loss not specified [RCV003986380] Chr2:106755586..134302739 [GRCh37]
Chr2:2q12.2-21.2		 pathogenic
NM_001199140.2(AMMECR1L):c.920A>G (p.Asn307Ser) single nucleotide variant not specified [RCV004409837] Chr2:127865107 [GRCh38]
Chr2:128622681 [GRCh37]
Chr2:2q14.3		 uncertain significance
NM_001199140.2(AMMECR1L):c.844A>G (p.Ile282Val) single nucleotide variant not specified [RCV004642834] Chr2:127865183 [GRCh38]
Chr2:128622757 [GRCh37]
Chr2:2q14.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2604
Count of miRNA genes:857
Interacting mature miRNAs:986
Transcripts:ENST00000272647, ENST00000393001
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407315716GWAS964692_HQT interval QTL GWAS964692 (human)3e-10QT intervalQT interval (CMO:0000235)2127862798127862799Human
406897157GWAS546133_Heducational attainment QTL GWAS546133 (human)7e-09educational attainment2127866537127866538Human
407030484GWAS679460_Hwheezing QTL GWAS679460 (human)0.000003wheezing2127876046127876047Human
406963757GWAS612733_Hsevere acute respiratory syndrome, COVID-19 QTL GWAS612733 (human)5e-09severe acute respiratory syndrome, COVID-192127871978127871979Human

Markers in Region
RH122312  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372128,630,846 - 128,631,120UniSTSGRCh37
Build 362128,347,316 - 128,347,590RGDNCBI36
Celera2121,941,799 - 121,942,073RGD
Cytogenetic Map2q21UniSTS
HuRef2120,937,145 - 120,937,419UniSTS
TNG Radiation Hybrid Map275033.0UniSTS
WI-17503  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372128,620,294 - 128,620,421UniSTSGRCh37
Build 362128,336,764 - 128,336,891RGDNCBI36
Celera2121,931,246 - 121,931,373RGD
Cytogenetic Map2q21UniSTS
HuRef2120,926,591 - 120,926,718UniSTS
GeneMap99-GB4 RH Map2459.78UniSTS
Whitehead-RH Map2742.5UniSTS
AFMa204xe5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372128,638,292 - 128,638,441UniSTSGRCh37
Build 362128,354,762 - 128,354,911RGDNCBI36
Celera2121,949,243 - 121,949,394RGD
Cytogenetic Map2q21UniSTS
HuRef2120,944,594 - 120,944,745UniSTS
Whitehead-RH Map2742.4UniSTS
NCBI RH Map21006.6UniSTS
RH70799  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372128,619,831 - 128,619,971UniSTSGRCh37
Build 362128,336,301 - 128,336,441RGDNCBI36
Celera2121,930,783 - 121,930,923RGD
Cytogenetic Map2q21UniSTS
HuRef2120,926,128 - 120,926,268UniSTS
GeneMap99-GB4 RH Map2462.47UniSTS
NCBI RH Map21001.4UniSTS
RH78129  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372128,620,151 - 128,620,285UniSTSGRCh37
Build 362128,336,621 - 128,336,755RGDNCBI36
Celera2121,931,103 - 121,931,237RGD
Cytogenetic Map2q21UniSTS
HuRef2120,926,448 - 120,926,582UniSTS
NCBI RH Map21006.2UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2432 2788 2245 4942 1723 2345 4 622 1948 464 2268 7281 6454 52 3708 847 1731 1612 171

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001199140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005263806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011511952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011511954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011511955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011511956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047445956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC012306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK024993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK026685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC067124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC084552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000272647   ⟹   ENSP00000272647
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,630 - 127,885,956 (-)Ensembl
Ensembl Acc Id: ENST00000393001   ⟹   ENSP00000376726
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,637 - 127,884,860 (-)Ensembl
Ensembl Acc Id: ENST00000679574   ⟹   ENSP00000506697
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,645 - 127,885,945 (-)Ensembl
Ensembl Acc Id: ENST00000679797   ⟹   ENSP00000505986
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,630 - 127,885,956 (-)Ensembl
Ensembl Acc Id: ENST00000680045   ⟹   ENSP00000506104
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,649 - 127,885,956 (-)Ensembl
Ensembl Acc Id: ENST00000680145   ⟹   ENSP00000506553
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,649 - 127,885,883 (-)Ensembl
Ensembl Acc Id: ENST00000680246   ⟹   ENSP00000505484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,649 - 127,885,967 (-)Ensembl
Ensembl Acc Id: ENST00000680431   ⟹   ENSP00000505675
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,654 - 127,885,945 (-)Ensembl
Ensembl Acc Id: ENST00000680603   ⟹   ENSP00000506318
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,649 - 127,885,574 (-)Ensembl
Ensembl Acc Id: ENST00000680886   ⟹   ENSP00000505606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,649 - 127,885,961 (-)Ensembl
Ensembl Acc Id: ENST00000681313   ⟹   ENSP00000505989
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,639 - 127,885,945 (-)Ensembl
Ensembl Acc Id: ENST00000681549   ⟹   ENSP00000505095
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,630 - 127,885,956 (-)Ensembl
Ensembl Acc Id: ENST00000681844   ⟹   ENSP00000505104
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,861,649 - 127,885,574 (-)Ensembl
Ensembl Acc Id: ENST00000695238   ⟹   ENSP00000511759
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2127,864,979 - 127,865,125 (-)Ensembl
RefSeq Acc Id: NM_001199140   ⟹   NP_001186069
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,861,630 - 127,885,956 (-)NCBI
GRCh372128,619,204 - 128,643,635 (-)NCBI
HuRef2120,925,501 - 120,949,646 (-)ENTREZGENE
CHM1_12128,624,214 - 128,648,542 (-)NCBI
T2T-CHM13v2.02128,296,887 - 128,321,215 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001410953   ⟹   NP_001397882
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,861,630 - 127,885,956 (-)NCBI
T2T-CHM13v2.02128,296,887 - 128,321,215 (-)NCBI
RefSeq Acc Id: NM_001410954   ⟹   NP_001397883
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,861,630 - 127,885,956 (-)NCBI
T2T-CHM13v2.02128,296,887 - 128,321,215 (-)NCBI
RefSeq Acc Id: NM_031445   ⟹   NP_113633
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,861,630 - 127,884,860 (-)NCBI
GRCh372128,619,204 - 128,643,635 (-)NCBI
Build 362128,335,674 - 128,358,904 (-)NCBI Archive
Celera2121,930,156 - 121,953,388 (-)RGD
HuRef2120,925,501 - 120,949,646 (-)ENTREZGENE
CHM1_12128,624,214 - 128,647,462 (-)NCBI
T2T-CHM13v2.02128,296,887 - 128,320,119 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005263806   ⟹   XP_005263863
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,861,630 - 127,885,956 (-)NCBI
GRCh372128,619,204 - 128,643,635 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011511956   ⟹   XP_011510258
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,866,912 - 127,885,956 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017005063   ⟹   XP_016860552
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,869,454 - 127,885,956 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047445956   ⟹   XP_047301912
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,869,454 - 127,885,956 (-)NCBI
RefSeq Acc Id: XM_054344108   ⟹   XP_054200083
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02128,296,887 - 128,321,215 (-)NCBI
RefSeq Acc Id: XM_054344109   ⟹   XP_054200084
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02128,304,711 - 128,321,215 (-)NCBI
RefSeq Acc Id: XM_054344110   ⟹   XP_054200085
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02128,302,169 - 128,321,215 (-)NCBI
RefSeq Acc Id: XM_054344111   ⟹   XP_054200086
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02128,304,711 - 128,321,215 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001186069 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397882 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397883 (Get FASTA)   NCBI Sequence Viewer  
  NP_113633 (Get FASTA)   NCBI Sequence Viewer  
  XP_005263863 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510258 (Get FASTA)   NCBI Sequence Viewer  
  XP_016860552 (Get FASTA)   NCBI Sequence Viewer  
  XP_047301912 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200083 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200084 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200085 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200086 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH16181 (Get FASTA)   NCBI Sequence Viewer  
  AAH78174 (Get FASTA)   NCBI Sequence Viewer  
  BAG65038 (Get FASTA)   NCBI Sequence Viewer  
  EAW95346 (Get FASTA)   NCBI Sequence Viewer  
  EAW95347 (Get FASTA)   NCBI Sequence Viewer  
  EAW95348 (Get FASTA)   NCBI Sequence Viewer  
  EAW95349 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000272647
  ENSP00000272647.6
  ENSP00000376726
  ENSP00000376726.1
  ENSP00000505095.1
  ENSP00000505104
  ENSP00000505104.1
  ENSP00000505484
  ENSP00000505484.1
  ENSP00000505606
  ENSP00000505606.1
  ENSP00000505675.1
  ENSP00000505986.1
  ENSP00000505989.1
  ENSP00000506104.1
  ENSP00000506318.1
  ENSP00000506553.1
  ENSP00000506697.1
  ENSP00000511759.1
GenBank Protein Q6DCA0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113633   ⟸   NM_031445
- Peptide Label: isoform 1
- UniProtKB: B4E276 (UniProtKB/Swiss-Prot),   Q6DCA0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001186069   ⟸   NM_001199140
- Peptide Label: isoform 1
- UniProtKB: B4E276 (UniProtKB/Swiss-Prot),   Q6DCA0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005263863   ⟸   XM_005263806
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011510258   ⟸   XM_011511956
- Peptide Label: isoform X3
- UniProtKB: A0A7P0Z4N3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016860552   ⟸   XM_017005063
- Peptide Label: isoform X4
- UniProtKB: A0A7P0Z4N3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000272647   ⟸   ENST00000272647
Ensembl Acc Id: ENSP00000376726   ⟸   ENST00000393001
Ensembl Acc Id: ENSP00000505484   ⟸   ENST00000680246
Ensembl Acc Id: ENSP00000506553   ⟸   ENST00000680145
Ensembl Acc Id: ENSP00000505986   ⟸   ENST00000679797
Ensembl Acc Id: ENSP00000505104   ⟸   ENST00000681844
Ensembl Acc Id: ENSP00000505675   ⟸   ENST00000680431
Ensembl Acc Id: ENSP00000505606   ⟸   ENST00000680886
Ensembl Acc Id: ENSP00000506104   ⟸   ENST00000680045
Ensembl Acc Id: ENSP00000506318   ⟸   ENST00000680603
Ensembl Acc Id: ENSP00000506697   ⟸   ENST00000679574
Ensembl Acc Id: ENSP00000505989   ⟸   ENST00000681313
Ensembl Acc Id: ENSP00000505095   ⟸   ENST00000681549
RefSeq Acc Id: XP_047301912   ⟸   XM_047445956
- Peptide Label: isoform X2
- UniProtKB: A0A7P0TAB6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000511759   ⟸   ENST00000695238
RefSeq Acc Id: NP_001397883   ⟸   NM_001410954
- Peptide Label: isoform 3
- UniProtKB: A0A7P0T9C2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397882   ⟸   NM_001410953
- Peptide Label: isoform 2
- UniProtKB: A0A7P0Z454 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200083   ⟸   XM_054344108
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054200085   ⟸   XM_054344110
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054200086   ⟸   XM_054344111
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054200084   ⟸   XM_054344109
- Peptide Label: isoform X2
- UniProtKB: A0A7P0TAB6 (UniProtKB/TrEMBL)
Protein Domains
AMMECR1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6DCA0-F1-model_v2 AlphaFold Q6DCA0 1-310 view protein structure

Promoters
RGD ID:6861506
Promoter ID:EPDNEW_H3918
Type:initiation region
Name:AMMECR1L_1
Description:AMMECR1 like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382127,885,947 - 127,886,007EPDNEW
RGD ID:6796767
Promoter ID:HG_KWN:34894
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   Lymphoblastoid
Transcripts:ENST00000272647
Position:
Human AssemblyChrPosition (strand)Source
Build 362128,360,191 - 128,360,691 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:28658 AgrOrtholog
COSMIC AMMECR1L COSMIC
Ensembl Genes ENSG00000144233 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000272647 ENTREZGENE
  ENST00000272647.10 UniProtKB/Swiss-Prot
  ENST00000393001 ENTREZGENE
  ENST00000393001.1 UniProtKB/Swiss-Prot
  ENST00000679574.1 UniProtKB/TrEMBL
  ENST00000679797.1 UniProtKB/TrEMBL
  ENST00000680045.1 UniProtKB/TrEMBL
  ENST00000680145.1 UniProtKB/TrEMBL
  ENST00000680246 ENTREZGENE
  ENST00000680246.1 UniProtKB/TrEMBL
  ENST00000680431.1 UniProtKB/TrEMBL
  ENST00000680603.1 UniProtKB/TrEMBL
  ENST00000680886 ENTREZGENE
  ENST00000680886.1 UniProtKB/TrEMBL
  ENST00000681313.1 UniProtKB/TrEMBL
  ENST00000681549.1 UniProtKB/TrEMBL
  ENST00000681844 ENTREZGENE
  ENST00000681844.1 UniProtKB/TrEMBL
  ENST00000695238.1 UniProtKB/TrEMBL
GTEx ENSG00000144233 GTEx
HGNC ID HGNC:28658 ENTREZGENE
Human Proteome Map AMMECR1L Human Proteome Map
InterPro AMMECR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AMMECR1_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AMMECR1_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AMMECR1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:83607 UniProtKB/Swiss-Prot
NCBI Gene 83607 ENTREZGENE
PANTHER AMMECR1-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13016 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AMMECR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162376350 PharmGKB
PROSITE AMMECR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF143447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A7P0T8F5_HUMAN UniProtKB/TrEMBL
  A0A7P0T9C2 ENTREZGENE, UniProtKB/TrEMBL
  A0A7P0TAB6 ENTREZGENE, UniProtKB/TrEMBL
  A0A7P0TAB7_HUMAN UniProtKB/TrEMBL
  A0A7P0TAH0_HUMAN UniProtKB/TrEMBL
  A0A7P0TAX1_HUMAN UniProtKB/TrEMBL
  A0A7P0TBJ3_HUMAN UniProtKB/TrEMBL
  A0A7P0Z454 ENTREZGENE, UniProtKB/TrEMBL
  A0A7P0Z4N3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8V8THZ2_HUMAN UniProtKB/TrEMBL
  AMERL_HUMAN UniProtKB/Swiss-Prot
  B4E276 ENTREZGENE
  Q6DCA0 ENTREZGENE
UniProt Secondary B4E276 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-10 AMMECR1L  AMMECR1 like    AMMECR1-like  Symbol and/or name change 5135510 APPROVED
2012-11-20 AMMECR1L  AMMECR1-like    AMME chromosomal region gene 1-like  Symbol and/or name change 5135510 APPROVED