H1-7 (H1.7 linker histone) - Rat Genome Database

Name: H1-7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: H1-7 (H1.7 linker histone) Homo sapiens

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Symbol:

H1-7

Name:

H1.7 linker histone

RGD ID:

1604474

HGNC Page

HGNC:24893

Description:

Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation; negative regulation of DNA recombination; and spermatid nucleus differentiation. Located in nucleus.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

H1 histone family member N, testis specific; H1 histone family, member N, testis-specific; H1.7; H1FNT; H1T2; HANP1; haploid germ cell-specific nuclear protein 1; histone H1.7; histone H1t2; testis secretory sperm-binding protein Li 223n; testis-specific H1 histone

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	48,328,980 - 48,330,279 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	48,328,980 - 48,330,279 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	48,722,763 - 48,724,062 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,009,030 - 47,010,329 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	47,520,294 - 47,521,593 (+)	NCBI		Celera
Cytogenetic Map	12	q13.11	NCBI
HuRef	12	45,755,928 - 45,757,227 (+)	NCBI		HuRef
CHM1_1	12	48,688,136 - 48,689,435 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	48,290,314 - 48,291,613 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2-palmitoylglycerol (EXP)

arsane (EXP)

arsenic atom (EXP)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

clothianidin (EXP)

dibutyl phthalate (ISO)

epoxiconazole (ISO)

p-chloromercuribenzoic acid (EXP)

titanium dioxide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IEA)

chromosome condensation (IBA,IEA)

negative regulation of DNA recombination (IBA)

sperm DNA condensation (ISS)

spermatid nucleus elongation (ISS)

spermatogenesis (IEA)

Cellular Component

chromatin (ISS)

chromosome (IEA)

male germ cell nucleus (ISO)

nucleus (HDA,IBA,IEA)

Molecular Function

ATP binding (IEA)

DNA binding (IEA)

double-stranded DNA binding (IBA)

nucleosomal DNA binding (IBA)

protein binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15710904	PMID:16055721	PMID:16533358	PMID:21630459	PMID:21873635	PMID:22650316	PMID:24614311	PMID:24781148	PMID:26689747	PMID:28514442	PMID:32296183
PMID:33961781	PMID:36180920

Genomics

Comparative Map Data

H1-7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	48,328,980 - 48,330,279 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	48,328,980 - 48,330,279 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	48,722,763 - 48,724,062 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,009,030 - 47,010,329 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	47,520,294 - 47,521,593 (+)	NCBI		Celera
Cytogenetic Map	12	q13.11	NCBI
HuRef	12	45,755,928 - 45,757,227 (+)	NCBI		HuRef
CHM1_1	12	48,688,136 - 48,689,435 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	48,290,314 - 48,291,613 (+)	NCBI		T2T-CHM13v2.0

H1f7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	98,153,863 - 98,155,188 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	98,153,867 - 98,155,174 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	98,255,982 - 98,257,307 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	98,255,986 - 98,257,293 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	98,086,413 - 98,087,738 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	98,084,016 - 98,085,313 (-)	NCBI		MGSCv36	mm8
Celera	15	100,387,598 - 100,388,923 (-)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	54.26	NCBI

H1f7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,287,569 - 131,288,936 (-)	NCBI		GRCr8
mRatBN7.2	7	129,408,521 - 129,409,888 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,408,359 - 129,409,930 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	131,213,591 - 131,214,958 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,439,117 - 133,440,484 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,351,612 - 133,352,979 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	139,871,491 - 139,872,858 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	139,871,479 - 139,872,900 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	139,015,809 - 139,017,176 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	136,995,394 - 136,996,761 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	125,899,914 - 125,901,281 (-)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

LOC106146871
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955500	7,329,361 - 7,329,842 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC117975443
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,677,304 - 45,861,164 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,672,412 - 45,857,925 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	40,244,979 - 40,262,470 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	41,280,957 - 41,282,281 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	41,281,177 - 41,281,944 (-)	Ensembl	panpan1.1		panPan2
PanPan1.1 Ensembl	12	41,281,177 - 41,281,944 (-)	NCBI	panpan1.1		panPan2

H1-7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	6,389,797 - 6,396,021 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	6,389,908 - 6,391,174 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	39,881,927 - 39,888,151 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	6,457,201 - 6,463,429 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	27	6,393,405 - 6,399,629 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	6,429,260 - 6,435,485 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	40,200,972 - 40,207,197 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101974551
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	66,964,013 - 66,964,967 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936512	6,199,894 - 6,200,786 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

H1-7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	78,698,577 - 78,700,109 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	78,699,291 - 78,700,227 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	81,891,927 - 81,892,942 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103238227
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	44,557,985 - 44,559,218 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	201,608,799 - 201,610,031 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101702847
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624816	3,931,613 - 3,932,549 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in H1-7
25 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3	copy number gain	See cases [RCV000139555]	Chr12:121271..133196807 [GRCh38] Chr12:282465..133773393 [GRCh37] Chr12:100698..132283466 [NCBI36] Chr12:12p13.33-q24.33	pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3	copy number gain	See cases [RCV000258805]	Chr12:1..133851895 [GRCh37] Chr12:12p13.33-q24.33	pathogenic\|likely pathogenic
GRCh37/hg19 12p11.21-q13.12(chr12:31886971-50360461)x3	copy number gain	See cases [RCV000207454]	Chr12:31886971..50360461 [GRCh37] Chr12:12p11.21-q13.12	pathogenic
GRCh37/hg19 12q11-13.12(chr12:37857750-49791459)x3	copy number gain	See cases [RCV000448835]	Chr12:37857750..49791459 [GRCh37] Chr12:12q11-13.12	pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3	copy number gain	See cases [RCV000510482]	Chr12:173787..133777902 [GRCh37] Chr12:12p13.33-q24.33	pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)	copy number gain	See cases [RCV000511643]	Chr12:173787..133777902 [GRCh37] Chr12:12p13.33-q24.33	pathogenic
NC_000012.11:g.26370251_54361538inv	inversion	not specified [RCV000714265]	Chr12:26370251..54361538 [GRCh37] Chr12:12p12.1-q13.13	uncertain significance
NM_181788.1(H1-7):c.112A>G (p.Thr38Ala)	single nucleotide variant	not specified [RCV004297175]	Chr12:48329403 [GRCh38] Chr12:48723186 [GRCh37] Chr12:12q13.11	uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3	copy number gain	not provided [RCV000750246]	Chr12:191619..133777645 [GRCh37] Chr12:12p13.33-q24.33	pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3	copy number gain	not provided [RCV000750253]	Chr12:621220..133779118 [GRCh37] Chr12:12p13.33-q24.33	pathogenic
GRCh37/hg19 12q11-13.12(chr12:37873948-49578619)x3	copy number gain	See cases [RCV001353185]	Chr12:37873948..49578619 [GRCh37] Chr12:12q11-13.12	likely pathogenic
GRCh37/hg19 12q11-13.12(chr12:37857750-49791459)	copy number gain	not specified [RCV002052988]	Chr12:37857750..49791459 [GRCh37] Chr12:12q11-13.12	pathogenic
GRCh37/hg19 12q12-13.11(chr12:44661149-48921204)x1	copy number loss	not provided [RCV002291537]	Chr12:44661149..48921204 [GRCh37] Chr12:12q12-13.11	pathogenic
NM_181788.1(H1-7):c.139G>A (p.Gly47Arg)	single nucleotide variant	not specified [RCV004337438]	Chr12:48329430 [GRCh38] Chr12:48723213 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.350C>T (p.Ala117Val)	single nucleotide variant	not specified [RCV004396429]	Chr12:48329641 [GRCh38] Chr12:48723424 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.278A>T (p.Lys93Met)	single nucleotide variant	not specified [RCV004396427]	Chr12:48329569 [GRCh38] Chr12:48723352 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.382C>T (p.Pro128Ser)	single nucleotide variant	not specified [RCV004396431]	Chr12:48329673 [GRCh38] Chr12:48723456 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.424C>G (p.Arg142Gly)	single nucleotide variant	not specified [RCV004396433]	Chr12:48329715 [GRCh38] Chr12:48723498 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.428C>A (p.Ala143Asp)	single nucleotide variant	not specified [RCV004396434]	Chr12:48329719 [GRCh38] Chr12:48723502 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.290A>C (p.His97Pro)	single nucleotide variant	not specified [RCV004396428]	Chr12:48329581 [GRCh38] Chr12:48723364 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.470G>A (p.Arg157His)	single nucleotide variant	not specified [RCV004396435]	Chr12:48329761 [GRCh38] Chr12:48723544 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.112A>T (p.Thr38Ser)	single nucleotide variant	not specified [RCV004396423]	Chr12:48329403 [GRCh38] Chr12:48723186 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.187T>A (p.Leu63Met)	single nucleotide variant	not specified [RCV004396425]	Chr12:48329478 [GRCh38] Chr12:48723261 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.373G>T (p.Val125Phe)	single nucleotide variant	not specified [RCV004396430]	Chr12:48329664 [GRCh38] Chr12:48723447 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.484C>T (p.Arg162Cys)	single nucleotide variant	not specified [RCV004396437]	Chr12:48329775 [GRCh38] Chr12:48723558 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.117G>C (p.Gln39His)	single nucleotide variant	not specified [RCV004396424]	Chr12:48329408 [GRCh38] Chr12:48723191 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.218G>A (p.Gly73Glu)	single nucleotide variant	not specified [RCV004396426]	Chr12:48329509 [GRCh38] Chr12:48723292 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.419G>A (p.Gly140Asp)	single nucleotide variant	not specified [RCV004396432]	Chr12:48329710 [GRCh38] Chr12:48723493 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.473G>A (p.Arg158His)	single nucleotide variant	not specified [RCV004396436]	Chr12:48329764 [GRCh38] Chr12:48723547 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.506G>A (p.Arg169Lys)	single nucleotide variant	not specified [RCV004396438]	Chr12:48329797 [GRCh38] Chr12:48723580 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.548A>G (p.Asn183Ser)	single nucleotide variant	not specified [RCV004396439]	Chr12:48329839 [GRCh38] Chr12:48723622 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.704G>A (p.Arg235Gln)	single nucleotide variant	not specified [RCV004396440]	Chr12:48329995 [GRCh38] Chr12:48723778 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.706A>G (p.Ser236Gly)	single nucleotide variant	not specified [RCV004396441]	Chr12:48329997 [GRCh38] Chr12:48723780 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.748G>A (p.Ala250Thr)	single nucleotide variant	not specified [RCV004396442]	Chr12:48330039 [GRCh38] Chr12:48723822 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.751C>A (p.Gln251Lys)	single nucleotide variant	not specified [RCV004396443]	Chr12:48330042 [GRCh38] Chr12:48723825 [GRCh37] Chr12:12q13.11	likely benign
NM_181788.1(H1-7):c.715C>G (p.Pro239Ala)	single nucleotide variant	not specified [RCV004627261]	Chr12:48330006 [GRCh38] Chr12:48723789 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.142G>A (p.Gly48Arg)	single nucleotide variant	not specified [RCV004627263]	Chr12:48329433 [GRCh38] Chr12:48723216 [GRCh37] Chr12:12q13.11	uncertain significance
NM_181788.1(H1-7):c.442C>T (p.Pro148Ser)	single nucleotide variant	not specified [RCV004627264]	Chr12:48329733 [GRCh38] Chr12:48723516 [GRCh37] Chr12:12q13.11	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	225
Count of miRNA genes:	213
Interacting mature miRNAs:	225
Transcripts:	ENST00000335017
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
407238885	GWAS887861_H	body height QTL GWAS887861 (human)		0.000002	body height (VT:0001253)	body height (CMO:0000106)	12	48330001	48330002	Human
407087078	GWAS736054_H	osteoarthritis, knee QTL GWAS736054 (human)		1e-08	osteoarthritis, knee		12	48329541	48329542	Human

Markers in Region

UniSTS:484656

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	12	48,722,813 - 48,723,989	UniSTS	GRCh37
Celera	12	47,520,344 - 47,521,520	UniSTS
HuRef	12	45,755,978 - 45,757,154	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system
1103	2185	2702	1980	4552	1456	1833	1	409	1335	253	1965	5822	5414	12	3574	611	1526	1332	158

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_181788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB121028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC024257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY302593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY496854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC118635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC119787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HM005636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000335017 ⟹ ENSP00000334805

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	12	48,328,980 - 48,330,279 (+)	Ensembl

RefSeq Acc Id:

NM_181788 ⟹ NP_861453

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	12	48,328,980 - 48,330,279 (+)	NCBI
GRCh37	12	48,722,763 - 48,724,062 (+)	RGD
Build 36	12	47,009,030 - 47,010,329 (+)	NCBI Archive
Celera	12	47,520,294 - 47,521,593 (+)	RGD
HuRef	12	45,755,928 - 45,757,227 (+)	RGD
CHM1_1	12	48,688,136 - 48,689,435 (+)	NCBI
T2T-CHM13v2.0	12	48,290,314 - 48,291,613 (+)	NCBI

Sequence:

show sequence

TAAGGAACTGTGGGTAGATGGTTTGCAGGACCACATACACACACAAAATAGCCGACTAAAGAAA
GCGGTGGAGATCGAGATCAGTAAGTTTGATTTGGGAACAAAACCCTGGAGACTCTATAGGTAGG
TGACTGTTGGGGGTGGACAGGCGCTGAAGACTTGGATTGGTTTAGACCTAGAAGGAAGTGGCAT
TTGATTGGTTATTATAAGTGAAAAGGGCCCCTCCCCGGGTGAGATATGCCAGCCCCATAATTAG
GACCTGAAAATCTCTGCCAGGCCTGCCTTTGTGACGTGGCCCAGTCTACCTCAGCTATGGAACA
GGCCTTGACTGGTGAGGCCCAAAGCCGGTGGCCCCGCAGAGGCGGGAGTGGGGCCATGGCTGAG
GCGCCTGGGCCCAGTGGCGAATCCCGAGGACACTCAGCCACTCAGCTGCCAGCGGAAAAAACTG
TCGGGGGACCATCGAGGGGCTGCTCAAGCTCCGTGCTCAGAGTGTCCCAGTTGGTGCTCCAGGC
CATCTCCACTCACAAAGGGCTGACTCTGGCAGCTCTCAAGAAGGAGCTCCGAAACGCCGGCTAC
GAAGTGCGCAGGAAGAGCGGCCGCCACGAAGCGCCCAGGGGGCAGGCCAAGGCCACGCTCCTCC
GGGTCAGCGGCAGCGACGCCGCCGGCTACTTCAGGGTCTGGAAGGTTCCCAAGCCCAGGAGAAA
GCCGGGACGCGCGAGGCAAGAGGAGGGCACGCGCGCTCCCTGGAGGACCCCAGCCGCGCCCCGG
AGCTCCCGGAGGCGCCGCCAGCCCCTTCGCAAGGCGGCCAGGAAGGCCAGAGAAGTGTGGAGAC
GGAACGCGAGGGCGAAAGCCAAGGCCAATGCCAGGGCGAGGAGGACCAGGAGGGCAAGGCCGAG
AGCCAAGGAGCCGCCGTGTGCCAGAGCCAAGGAGGAAGCGGGAGCGACAGCGGCAGACGAGGGG
CGAGGACAGGCCGTGAAGGAAGACACCACGCCGAGGTCAGGGAAGGACAAGAGGCGAAGCTCCA
AGCCCAGGGAAGAGAAGCAGGAGCCCAAGAAGCCCGCACAGCGGACCATCCAGTAGCCAACGCG
GGCTAAAACCGACCGGACATCTAGCGGGCAGGGGAAGACTCCACTAAAGACTTCCACAAAGACC
TCCCCTAAATCTGAAGGTCTTCCTGATCCAGTTGGGAATGCATCTTGTGGGAGCAGCTTCACTC
CCACCACGGACCAATGCCTTTCCCCCATAGGCCCCAAGAAGAGCGGCTGTCACACTCATTGAAA
TGAAATGGACCTCTAGACCA

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Protein Sequences


Protein RefSeqs	NP_861453	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI18636	(Get FASTA)	NCBI Sequence Viewer
	AAI19788	(Get FASTA)	NCBI Sequence Viewer
	AAP60022	(Get FASTA)	NCBI Sequence Viewer
	AAS49492	(Get FASTA)	NCBI Sequence Viewer
	AEE61233	(Get FASTA)	NCBI Sequence Viewer
	BAD13382	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000334805
	ENSP00000334805.1
GenBank Protein	Q75WM6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_861453 ⟸ NM_181788

- UniProtKB:

Q5GKZ5 (UniProtKB/Swiss-Prot), Q147U8 (UniProtKB/Swiss-Prot), Q7Z694 (UniProtKB/Swiss-Prot), Q75WM6 (UniProtKB/Swiss-Prot), A0A140VK96 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEQALTGEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLV
LQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKP
RRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRA
RPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQRTIQ

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Ensembl Acc Id:

ENSP00000334805 ⟸ ENST00000335017

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q75WM6-F1-model_v2	AlphaFold	Q75WM6	1-255	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:24893	AgrOrtholog
COSMIC	H1-7	COSMIC
Ensembl Genes	ENSG00000187166	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000335017	ENTREZGENE
	ENST00000335017.1	UniProtKB/Swiss-Prot
GTEx	ENSG00000187166	GTEx
HGNC ID	HGNC:24893	ENTREZGENE
Human Proteome Map	H1-7	Human Proteome Map
KEGG Report	hsa:341567	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	341567	ENTREZGENE
OMIM	618565	OMIM
PharmGKB	PA166351836	PharmGKB
UniProt	A0A140VK96	ENTREZGENE, UniProtKB/TrEMBL
	H1FNT_HUMAN	UniProtKB/Swiss-Prot
	Q147U8	ENTREZGENE
	Q5GKZ5	ENTREZGENE
	Q75WM6	ENTREZGENE
	Q7Z694	ENTREZGENE
UniProt Secondary	Q147U8	UniProtKB/Swiss-Prot
	Q5GKZ5	UniProtKB/Swiss-Prot
	Q7Z694	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-07-30	H1-7	H1.7 linker histone	H1FNT	H1 histone family member N, testis specific	Symbol and/or name change	5135510	APPROVED
2015-11-24	H1FNT	H1 histone family member N, testis specific		H1 histone family, member N, testis-specific	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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