LRATD1 (LRAT domain containing 1) - Rat Genome Database

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Gene: LRATD1 (LRAT domain containing 1) Homo sapiens
Analyze
Symbol: LRATD1
Name: LRAT domain containing 1
RGD ID: 1602648
HGNC Page HGNC:20743
Description: Involved in cell morphogenesis and cell motility. Predicted to be located in cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FAM84A; family with sequence similarity 84 member A; family with sequence similarity 84, member A; FLJ35392; neurologic sensory protein 1; neurological/sensory 1; NSE1; PP11517
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38214,632,717 - 14,651,916 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl214,632,700 - 14,650,814 (+)EnsemblGRCh38hg38GRCh38
GRCh37214,772,841 - 14,792,040 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36214,690,307 - 14,693,898 (+)NCBINCBI36Build 36hg18NCBI36
Celera214,690,800 - 14,698,160 (+)NCBICelera
Cytogenetic Map2p24.3NCBI
HuRef214,623,272 - 14,630,632 (+)NCBIHuRef
CHM1_1214,702,276 - 14,709,636 (+)NCBICHM1_1
T2T-CHM13v2.0214,663,504 - 14,682,703 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell morphogenesis  (IBA,IMP)
cell motility  (IBA,IMP)

Cellular Component
cytoplasm  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Schizophrenia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334   PMID:15815621   PMID:16820875   PMID:21873635   PMID:22589738   PMID:22990118   PMID:23824909   PMID:32296183   PMID:32814053   PMID:33751775  
PMID:33961781  


Genomics

Comparative Map Data
LRATD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38214,632,717 - 14,651,916 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl214,632,700 - 14,650,814 (+)EnsemblGRCh38hg38GRCh38
GRCh37214,772,841 - 14,792,040 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36214,690,307 - 14,693,898 (+)NCBINCBI36Build 36hg18NCBI36
Celera214,690,800 - 14,698,160 (+)NCBICelera
Cytogenetic Map2p24.3NCBI
HuRef214,623,272 - 14,630,632 (+)NCBIHuRef
CHM1_1214,702,276 - 14,709,636 (+)NCBICHM1_1
T2T-CHM13v2.0214,663,504 - 14,682,703 (+)NCBIT2T-CHM13v2.0
Lratd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391214,197,599 - 14,202,039 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1214,196,831 - 14,202,055 (-)EnsemblGRCm39 Ensembl
GRCm381214,147,598 - 14,152,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1214,146,830 - 14,152,054 (-)EnsemblGRCm38mm10GRCm38
MGSCv371214,154,404 - 14,158,844 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361214,173,138 - 14,177,578 (-)NCBIMGSCv36mm8
Celera1214,497,016 - 14,501,453 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map126.93NCBI
Lratd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8642,646,515 - 42,650,988 (-)NCBIGRCr8
mRatBN7.2636,916,969 - 36,922,143 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl636,913,469 - 36,922,319 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx637,229,678 - 37,234,169 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0637,544,351 - 37,548,842 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0636,994,065 - 36,998,553 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0639,358,285 - 39,363,458 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl639,358,985 - 39,363,458 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0648,123,155 - 48,128,472 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4637,782,015 - 37,786,488 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1637,785,856 - 37,789,250 (-)NCBI
Celera636,259,766 - 36,264,239 (-)NCBICelera
Cytogenetic Map6q15NCBI
Lratd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554878,452,621 - 8,454,585 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554878,452,413 - 8,454,585 (+)NCBIChiLan1.0ChiLan1.0
LRATD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212111,875,720 - 111,878,956 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A111,879,692 - 111,884,222 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A14,630,016 - 14,635,367 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl2A14,767,049 - 14,767,927 (+)Ensemblpanpan1.1panPan2
LRATD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11710,658,511 - 10,660,730 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1710,659,777 - 10,660,685 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1710,601,907 - 10,610,106 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01710,781,633 - 10,789,835 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1710,782,798 - 10,783,706 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11710,646,902 - 10,655,099 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01710,657,481 - 10,665,043 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01710,679,556 - 10,687,756 (+)NCBIUU_Cfam_GSD_1.0
Lratd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629255,149,649 - 55,150,748 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493735985,928 - 86,755 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRATD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3122,716,040 - 122,731,791 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13122,716,029 - 122,720,957 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23143,905,448 - 143,910,293 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRATD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11493,016,709 - 93,022,670 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1493,020,404 - 93,021,282 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604519,244,941 - 19,251,510 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lratd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248651,721,911 - 1,724,115 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248651,719,711 - 1,724,056 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LRATD1
11 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2p25.3-23.1(chr2:30141-31766749)x3 copy number gain See cases [RCV000052929] Chr2:30141..31766749 [GRCh38]
Chr2:30141..31991818 [GRCh37]
Chr2:20141..31845322 [NCBI36]
Chr2:2p25.3-23.1
pathogenic
GRCh38/hg38 2p25.3-24.3(chr2:30342-14866951)x3 copy number gain See cases [RCV000052931] Chr2:30342..14866951 [GRCh38]
Chr2:30342..15007075 [GRCh37]
Chr2:20342..14924526 [NCBI36]
Chr2:2p25.3-24.3
pathogenic
GRCh38/hg38 2p25.3-16.1(chr2:66097-55570637)x3 copy number gain See cases [RCV000052933] Chr2:66097..55570637 [GRCh38]
Chr2:66097..55797773 [GRCh37]
Chr2:56097..55651277 [NCBI36]
Chr2:2p25.3-16.1
pathogenic
GRCh38/hg38 2p25.2-24.3(chr2:6531172-16103799)x1 copy number loss See cases [RCV000053978] Chr2:6531172..16103799 [GRCh38]
Chr2:6671304..16243921 [GRCh37]
Chr2:6588755..16161372 [NCBI36]
Chr2:2p25.2-24.3
pathogenic
GRCh38/hg38 2p25.3-23.2(chr2:30341-28419664)x3 copy number gain See cases [RCV000135398] Chr2:30341..28419664 [GRCh38]
Chr2:30341..28642531 [GRCh37]
Chr2:20341..28496035 [NCBI36]
Chr2:2p25.3-23.2
pathogenic
GRCh38/hg38 2p24.3(chr2:13664310-16228425)x1 copy number loss See cases [RCV000137049] Chr2:13664310..16228425 [GRCh38]
Chr2:13804435..16409693 [GRCh37]
Chr2:13721886..16273174 [NCBI36]
Chr2:2p24.3
pathogenic
GRCh38/hg38 2p25.3-23.3(chr2:17019-26318846)x3 copy number gain See cases [RCV000137344] Chr2:17019..26318846 [GRCh38]
Chr2:17019..26541714 [GRCh37]
Chr2:7019..26395218 [NCBI36]
Chr2:2p25.3-23.3
pathogenic
GRCh38/hg38 2p25.3-24.1(chr2:1664615-23664142)x3 copy number gain See cases [RCV000137913] Chr2:1664615..23664142 [GRCh38]
Chr2:1668387..23887012 [GRCh37]
Chr2:1647394..23740517 [NCBI36]
Chr2:2p25.3-24.1
pathogenic|likely pathogenic
GRCh38/hg38 2p25.3-24.1(chr2:17019-20001056)x3 copy number gain See cases [RCV000141226] Chr2:17019..20001056 [GRCh38]
Chr2:17019..20200817 [GRCh37]
Chr2:7019..20064298 [NCBI36]
Chr2:2p25.3-24.1
pathogenic
GRCh38/hg38 2p25.3-22.3(chr2:12770-33711509)x3 copy number gain See cases [RCV000141829] Chr2:12770..33711509 [GRCh38]
Chr2:12770..33936576 [GRCh37]
Chr2:2770..33790080 [NCBI36]
Chr2:2p25.3-22.3
pathogenic
GRCh38/hg38 2p25.3-23.3(chr2:12770-25039694)x3 copy number gain See cases [RCV000141877] Chr2:12770..25039694 [GRCh38]
Chr2:12770..25262563 [GRCh37]
Chr2:2770..25116067 [NCBI36]
Chr2:2p25.3-23.3
pathogenic
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3 copy number gain See cases [RCV000141494] Chr2:7495123..87705899 [GRCh38]
Chr2:7635254..88005418 [GRCh37]
Chr2:7552705..87786533 [NCBI36]
Chr2:2p25.1-11.2
benign
GRCh38/hg38 2p25.3-21(chr2:236816-45983232)x3 copy number gain See cases [RCV000143682] Chr2:236816..45983232 [GRCh38]
Chr2:236816..46210371 [GRCh37]
Chr2:226816..46063875 [NCBI36]
Chr2:2p25.3-21
pathogenic
GRCh37/hg19 2p24.3(chr2:14617464-16467586)x1 copy number loss See cases [RCV000446084] Chr2:14617464..16467586 [GRCh37]
Chr2:2p24.3
pathogenic
NC_000002.11:g.(?_11326144)_(16240708_?)del deletion Schizophrenia [RCV000416804] Chr2:11326144..16240708 [GRCh37]
Chr2:11243595..16158159 [NCBI36]
Chr2:2p25.1-24.3
likely pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p25.3-24.1(chr2:12770-20081474)x3 copy number gain See cases [RCV000510934] Chr2:12770..20081474 [GRCh37]
Chr2:2p25.3-24.1
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
NC_000002.12:g.(?_11177745)_(16113827_?)del deletion Schizophrenia [RCV000754225] Chr2:11177745..16113827 [GRCh38]
Chr2:2p25.1-24.3
likely pathogenic
GRCh37/hg19 2p24.3-24.2(chr2:12269293-18259781)x3 copy number gain not provided [RCV000847286] Chr2:12269293..18259781 [GRCh37]
Chr2:2p24.3-24.2
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p25.1-24.3(chr2:8935077-15722794)x1 copy number loss not provided [RCV001836520] Chr2:8935077..15722794 [GRCh37]
Chr2:2p25.1-24.3
uncertain significance
GRCh37/hg19 2p24.3(chr2:14774068-15679480)x1 copy number loss not provided [RCV002214219] Chr2:14774068..15679480 [GRCh37]
Chr2:2p24.3
likely pathogenic
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13
pathogenic
NM_145175.4(LRATD1):c.515C>G (p.Ala172Gly) single nucleotide variant not specified [RCV004298621] Chr2:14634494 [GRCh38]
Chr2:14774618 [GRCh37]
Chr2:2p24.3
uncertain significance
GRCh37/hg19 2p25.3-22.3(chr2:706460-35523639)x3 copy number gain not provided [RCV002473946] Chr2:706460..35523639 [GRCh37]
Chr2:2p25.3-22.3
pathogenic
GRCh37/hg19 2p24.3(chr2:14712689-14901673)x1 copy number loss not provided [RCV002473813] Chr2:14712689..14901673 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.868G>T (p.Asp290Tyr) single nucleotide variant not specified [RCV004284983] Chr2:14634847 [GRCh38]
Chr2:14774971 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.613G>C (p.Glu205Gln) single nucleotide variant not specified [RCV004322722] Chr2:14634592 [GRCh38]
Chr2:14774716 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.101C>G (p.Ala34Gly) single nucleotide variant not specified [RCV004349219] Chr2:14634080 [GRCh38]
Chr2:14774204 [GRCh37]
Chr2:2p24.3
uncertain significance
GRCh37/hg19 2p24.3(chr2:12289529-16104486)x1 copy number loss not specified [RCV003986345] Chr2:12289529..16104486 [GRCh37]
Chr2:2p24.3
pathogenic
GRCh37/hg19 2p25.2-24.1(chr2:6375088-23538518)x3 copy number gain not specified [RCV003986320] Chr2:6375088..23538518 [GRCh37]
Chr2:2p25.2-24.1
pathogenic
GRCh37/hg19 2p25.3-22.3(chr2:12771-35541353)x3 copy number gain See cases [RCV004442780] Chr2:12771..35541353 [GRCh37]
Chr2:2p25.3-22.3
pathogenic
NM_145175.4(LRATD1):c.120T>G (p.Asp40Glu) single nucleotide variant not specified [RCV004410647] Chr2:14634099 [GRCh38]
Chr2:14774223 [GRCh37]
Chr2:2p24.3
likely benign
NM_145175.4(LRATD1):c.176C>T (p.Pro59Leu) single nucleotide variant not specified [RCV004410648] Chr2:14634155 [GRCh38]
Chr2:14774279 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.410C>T (p.Pro137Leu) single nucleotide variant not specified [RCV004410649] Chr2:14634389 [GRCh38]
Chr2:14774513 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.505G>A (p.Ala169Thr) single nucleotide variant not specified [RCV004410650] Chr2:14634484 [GRCh38]
Chr2:14774608 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.744C>G (p.His248Gln) single nucleotide variant not specified [RCV004410651] Chr2:14634723 [GRCh38]
Chr2:14774847 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.809G>A (p.Arg270His) single nucleotide variant not specified [RCV004410652] Chr2:14634788 [GRCh38]
Chr2:14774912 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.81C>G (p.Asp27Glu) single nucleotide variant not specified [RCV004410653] Chr2:14634060 [GRCh38]
Chr2:14774184 [GRCh37]
Chr2:2p24.3
uncertain significance
NM_145175.4(LRATD1):c.830G>A (p.Arg277His) single nucleotide variant not specified [RCV004637447] Chr2:14634809 [GRCh38]
Chr2:14774933 [GRCh37]
Chr2:2p24.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3596
Count of miRNA genes:1116
Interacting mature miRNAs:1364
Transcripts:ENST00000295092, ENST00000331243, ENST00000464947, ENST00000497769
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407220214GWAS869190_Htrauma exposure measurement QTL GWAS869190 (human)0.000002trauma exposure measurement21464000714640008Human

Markers in Region
SHGC-36750  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37214,777,204 - 14,777,328UniSTSGRCh37
Build 36214,694,655 - 14,694,779RGDNCBI36
Celera214,695,194 - 14,695,318RGD
Cytogenetic Map2p24.3UniSTS
HuRef214,627,666 - 14,627,790UniSTS
RH99165  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37214,775,965 - 14,776,084UniSTSGRCh37
Build 36214,693,416 - 14,693,535RGDNCBI36
Celera214,693,955 - 14,694,074RGD
Cytogenetic Map2p24.3UniSTS
HuRef214,626,427 - 14,626,546UniSTS
GeneMap99-GB4 RH Map256.45UniSTS
RH78874  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37214,779,978 - 14,780,098UniSTSGRCh37
Build 36214,697,429 - 14,697,549RGDNCBI36
Celera214,697,968 - 14,698,088RGD
Cytogenetic Map2p24.3UniSTS
HuRef214,630,440 - 14,630,560UniSTS
NCBI RH Map265.3UniSTS
D2S1661E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37214,777,223 - 14,777,338UniSTSGRCh37
Build 36214,694,674 - 14,694,789RGDNCBI36
Celera214,695,213 - 14,695,328RGD
Cytogenetic Map2p24.3UniSTS
HuRef214,627,685 - 14,627,800UniSTS
GeneMap99-GB4 RH Map256.45UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2418 2788 2228 4922 1700 2258 5 607 1209 447 2231 6536 5742 34 3719 1 837 1713 1542 174 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001369364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_144632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC011897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF086407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF370404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI432449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ417080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK092654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI547868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM998595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX113099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY017941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000295092   ⟹   ENSP00000295092
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl214,632,717 - 14,640,041 (+)Ensembl
Ensembl Acc Id: ENST00000331243   ⟹   ENSP00000330681
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl214,632,700 - 14,637,227 (+)Ensembl
Ensembl Acc Id: ENST00000464947
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl214,635,496 - 14,649,641 (+)Ensembl
Ensembl Acc Id: ENST00000497769
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl214,635,091 - 14,650,814 (+)Ensembl
RefSeq Acc Id: NM_001369364   ⟹   NP_001356293
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38214,632,717 - 14,640,041 (+)NCBI
T2T-CHM13v2.0214,663,504 - 14,670,828 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145175   ⟹   NP_660158
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38214,632,717 - 14,640,041 (+)NCBI
GRCh37214,772,810 - 14,780,170 (+)RGD
Build 36214,690,307 - 14,693,898 (+)NCBI Archive
Celera214,690,800 - 14,698,160 (+)RGD
HuRef214,623,272 - 14,630,632 (+)RGD
CHM1_1214,702,276 - 14,709,636 (+)NCBI
T2T-CHM13v2.0214,663,504 - 14,670,828 (+)NCBI
Sequence:
RefSeq Acc Id: NR_144632
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38214,632,717 - 14,651,916 (+)NCBI
T2T-CHM13v2.0214,663,504 - 14,682,703 (+)NCBI
Sequence:
RefSeq Acc Id: NP_660158   ⟸   NM_145175
- UniProtKB: Q8NAH7 (UniProtKB/Swiss-Prot),   Q86UZ2 (UniProtKB/Swiss-Prot),   A6NP76 (UniProtKB/Swiss-Prot),   Q8TAM5 (UniProtKB/Swiss-Prot),   Q96KN4 (UniProtKB/Swiss-Prot),   B2RB24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001356293   ⟸   NM_001369364
- UniProtKB: Q96KN4 (UniProtKB/Swiss-Prot),   Q8NAH7 (UniProtKB/Swiss-Prot),   Q86UZ2 (UniProtKB/Swiss-Prot),   A6NP76 (UniProtKB/Swiss-Prot),   Q8TAM5 (UniProtKB/Swiss-Prot),   B2RB24 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000330681   ⟸   ENST00000331243
Ensembl Acc Id: ENSP00000295092   ⟸   ENST00000295092
Protein Domains
LRAT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96KN4-F1-model_v2 AlphaFold Q96KN4 1-292 view protein structure

Promoters
RGD ID:6859670
Promoter ID:EPDNEW_H3000
Type:initiation region
Name:FAM84A_1
Description:family with sequence similarity 84 member A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38214,632,722 - 14,632,782EPDNEW
RGD ID:6797471
Promoter ID:HG_KWN:31578
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000331243,   ENST00000359969,   OTTHUMT00000239308
Position:
Human AssemblyChrPosition (strand)Source
Build 36214,690,041 - 14,690,541 (+)MPROMDB
RGD ID:6797472
Promoter ID:HG_KWN:31579
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000381456,   OTTHUMT00000323612,   OTTHUMT00000323614,   UC010EXK.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36214,692,041 - 14,692,541 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:20743 AgrOrtholog
COSMIC LRATD1 COSMIC
Ensembl Genes ENSG00000162981 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000295092 ENTREZGENE
  ENST00000295092.3 UniProtKB/Swiss-Prot
  ENST00000331243 ENTREZGENE
  ENST00000331243.4 UniProtKB/Swiss-Prot
Gene3D-CATH endopeptidase domain like (from Nostoc punctiforme) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000162981 GTEx
HGNC ID HGNC:20743 ENTREZGENE
Human Proteome Map LRATD1 Human Proteome Map
InterPro LRAT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRATD1_LRATD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:151354 UniProtKB/Swiss-Prot
NCBI Gene 151354 ENTREZGENE
OMIM 611234 OMIM
PANTHER PROTEIN FAM84B-RELATED UniProtKB/TrEMBL
  PROTEIN LRATD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46341 UniProtKB/Swiss-Prot
Pfam LRAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142671854 PharmGKB
PROSITE LRAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6NP76 ENTREZGENE
  B2RB24 ENTREZGENE, UniProtKB/TrEMBL
  FA84A_HUMAN UniProtKB/Swiss-Prot
  Q86UZ2 ENTREZGENE
  Q8NAH7 ENTREZGENE
  Q8TAM5 ENTREZGENE
  Q96KN4 ENTREZGENE
UniProt Secondary A6NP76 UniProtKB/Swiss-Prot
  Q86UZ2 UniProtKB/Swiss-Prot
  Q8NAH7 UniProtKB/Swiss-Prot
  Q8TAM5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-05 LRATD1  LRAT domain containing 1  FAM84A  family with sequence similarity 84 member A  Symbol and/or name change 5135510 APPROVED
2015-11-24 FAM84A  family with sequence similarity 84 member A    family with sequence similarity 84, member A  Symbol and/or name change 5135510 APPROVED