MARCHF10 (membrane associated ring-CH-type finger 10) - Rat Genome Database

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Gene: MARCHF10 (membrane associated ring-CH-type finger 10) Homo sapiens
Analyze
Symbol: MARCHF10
Name: membrane associated ring-CH-type finger 10
RGD ID: 1601818
HGNC Page HGNC:26655
Description: Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FLJ35757; MARCH-X; MARCH10; membrane associated ring finger 10; membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase; membrane-associated RING finger protein 10; membrane-associated RING-CH protein X; probable E3 ubiquitin-protein ligase MARCH10; probable E3 ubiquitin-protein ligase MARCHF10; ring finger protein 190; RING-type E3 ubiquitin transferase MARCH10; RING-type E3 ubiquitin transferase MARCHF10; RNF190; testis secretory sperm-binding protein Li 228n
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381762,701,314 - 62,808,314 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1762,701,314 - 62,808,344 (-)EnsemblGRCh38hg38GRCh38
GRCh371760,778,675 - 60,885,675 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361758,132,407 - 58,239,437 (-)NCBINCBI36Build 36hg18NCBI36
Celera1755,166,551 - 55,273,592 (-)NCBICelera
Cytogenetic Map17q23.2NCBI
HuRef1756,145,700 - 56,254,053 (-)NCBIHuRef
CHM1_11760,842,970 - 60,949,946 (-)NCBICHM1_1
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MARCHF10Human1,2-dimethylhydrazine decreases expressionISORGD:161704364804641,2-Dimethylhydrazine results in decreased expression of MARCHF10 mRNACTDPMID:22206623
MARCHF10Human17alpha-ethynylestradiol affects expressionISORGD:16170436480464Ethinyl Estradiol affects the expression of MARCHF10 mRNACTDPMID:17555576
MARCHF10Human17beta-estradiol 3-benzoate decreases methylationISORGD:13116926480464estradiol 3-benzoate results in decreased methylation of MARCHF10 promoterCTDPMID:27415467
MARCHF10Humanbenzo[a]pyrene affects methylationEXP 6480464Benzo(a)pyrene affects the methylation of MARCHF10 5' UTRCTDPMID:27901495
MARCHF10Humanbenzo[a]pyrene decreases methylationEXP 6480464Benzo(a)pyrene results in decreased methylation of MARCHF10 promoterCTDPMID:27901495
MARCHF10Humanbenzo[a]pyrene increases methylationEXP 6480464Benzo(a)pyrene results in increased methylation of MARCHF10 3' UTRCTDPMID:27901495
MARCHF10Humanbenzo[e]pyrene increases methylationEXP 6480464benzo(e)pyrene results in increased methylation of MARCHF10 exonCTDPMID:30157460
MARCHF10Humanbisphenol A decreases expressionISORGD:13116926480464bisphenol A results in decreased expression of MARCHF10 mRNACTDPMID:25181051
MARCHF10Humanchlorpyrifos decreases expressionISORGD:16170436480464Chlorpyrifos results in decreased expression of MARCHF10 mRNACTDPMID:37019170
MARCHF10Humanethylparaben decreases expressionEXP 6480464ethyl-p-hydroxybenzoate results in decreased expression of MARCHF10 mRNACTDPMID:37690743
MARCHF10Humanfenvalerate increases expressionISORGD:13116926480464fenvalerate results in increased expression of MARCHF10 mRNACTDPMID:30307764
MARCHF10Humanfuran increases methylationISORGD:13116926480464furan results in increased methylation of MARCHF10 geneCTDPMID:22079235
MARCHF10Humangentamycin increases expressionISORGD:13116926480464Gentamicins results in increased expression of MARCHF10 mRNACTDPMID:33387578
MARCHF10Humanmethapyrilene increases methylationEXP 6480464Methapyrilene results in increased methylation of MARCHF10 exonCTDPMID:30157460
MARCHF10Humansodium arsenite increases expressionEXP 6480464sodium arsenite results in increased expression of MARCHF10 mRNACTDPMID:29301061
MARCHF10Humantitanium dioxide decreases expressionISORGD:16170436480464titanium dioxide results in decreased expression of MARCHF10 mRNACTDPMID:29264374
MARCHF10Humantrichloroethene increases expressionISORGD:13116926480464Trichloroethylene results in increased expression of MARCHF10 mRNACTDPMID:33387578
MARCHF10Humanvancomycin increases expressionISORGD:16170436480464Vancomycin results in increased expression of MARCHF10 mRNACTDPMID:18930951

1 to 18 of 18 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MARCHF10Humanprotein ubiquitination involved_inIEAUniPathway:UPA00143150520179 UniProtGO_REF:0000041

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MARCHF10Humanmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
MARCHF10Humanprotein binding enablesIPIUniProtKB:Q96HA8|UniProtKB:Q9H3U1|UniProtKB:Q9NQW6-2150520179 PMID:25416956IntActPMID:25416956
MARCHF10Humanprotein binding enablesIPIUniProtKB:O43464|UniProtKB:Q7Z699|UniProtKB:Q8WXH2150520179 PMID:32814053IntActPMID:32814053
MARCHF10Humanprotein binding enablesIPIUniProtKB:Q9H3U1150520179 PMID:31515488, PMID:32296183IntActPMID:31515488|PMID:32296183
MARCHF10Humantransferase activity enablesIEAUniProtKB-KW:KW-0808150520179 UniProtGO_REF:0000043
MARCHF10Humanzinc ion binding enablesIEAInterPro:IPR011016150520179 InterProGO_REF:0000002
MARCHF10Humanzinc ion binding enablesIEAUniProtKB-KW:KW-0863150520179 UniProtGO_REF:0000043


#
Reference Title
Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:14702039   PMID:15489334   PMID:17604280   PMID:19549727   PMID:19724895   PMID:19851296   PMID:20198315   PMID:21658281   PMID:21832049   PMID:21873635   PMID:23602568  
PMID:23686814   PMID:24722188   PMID:25416956   PMID:27107014   PMID:31515488   PMID:32296183   PMID:32814053  



MARCHF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381762,701,314 - 62,808,314 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1762,701,314 - 62,808,344 (-)EnsemblGRCh38hg38GRCh38
GRCh371760,778,675 - 60,885,675 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361758,132,407 - 58,239,437 (-)NCBINCBI36Build 36hg18NCBI36
Celera1755,166,551 - 55,273,592 (-)NCBICelera
Cytogenetic Map17q23.2NCBI
HuRef1756,145,700 - 56,254,053 (-)NCBIHuRef
CHM1_11760,842,970 - 60,949,946 (-)NCBICHM1_1
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBIT2T-CHM13v2.0
Marchf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911105,251,624 - 105,348,527 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11105,251,624 - 105,347,561 (-)EnsemblGRCm39 Ensembl
GRCm3811105,360,798 - 105,457,701 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11105,360,798 - 105,456,735 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711105,469,840 - 105,499,479 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611105,217,744 - 105,272,814 (-)NCBIMGSCv36mm8
Celera11117,094,272 - 117,123,876 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.73NCBI
Marchf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81090,832,647 - 90,975,700 (-)NCBIGRCr8
mRatBN7.21090,332,783 - 90,423,109 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1090,332,784 - 90,421,588 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1095,382,178 - 95,471,096 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01094,845,350 - 94,934,268 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01090,263,550 - 90,352,488 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01093,591,187 - 93,681,507 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1093,591,188 - 93,679,974 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01093,350,038 - 93,439,947 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41094,762,789 - 94,855,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11094,777,159 - 94,870,147 (-)NCBI
Celera1089,015,563 - 89,104,950 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Marchf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554788,931,191 - 9,018,656 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554788,931,511 - 9,024,645 (+)NCBIChiLan1.0ChiLan1.0
MARCHF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21978,856,475 - 79,129,525 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11783,674,996 - 83,947,072 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01756,765,318 - 57,005,576 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11761,914,713 - 62,027,464 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1761,914,713 - 62,027,464 (-)Ensemblpanpan1.1panPan2
MARCHF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1910,880,225 - 10,968,991 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl910,880,226 - 10,961,157 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha911,905,886 - 11,994,600 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0912,541,972 - 12,630,777 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl912,541,973 - 12,622,742 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1911,490,017 - 11,578,452 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0915,954,881 - 16,043,271 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0915,958,697 - 16,047,459 (+)NCBIUU_Cfam_GSD_1.0
Marchf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560215,612,955 - 15,699,910 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365413,494,464 - 3,618,580 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365413,494,590 - 3,581,621 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARCHF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,969,769 - 16,052,680 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11215,969,915 - 16,052,445 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,861,982 - 15,944,352 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MARCHF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11658,466,882 - 58,574,222 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607729,099,127 - 29,210,962 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Marchf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624849220,875 - 316,789 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624849224,553 - 454,822 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in MARCHF10
89 total Variants

1 to 10 of 106 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2
pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3
pathogenic
GRCh37/hg19 17q23-24(chr17:59209629-64222315)x3 copy number gain See cases [RCV000052485] Chr17:59209629..64222315 [GRCh37]
Chr17:56564411..61652777 [NCBI36]
Chr17:17q23-24
pathogenic
NM_001100875.2(MARCH10):c.877G>A (p.Glu293Lys) single nucleotide variant Malignant melanoma [RCV000071595] Chr17:62736991 [GRCh38]
Chr17:60814352 [GRCh37]
Chr17:58168084 [NCBI36]
Chr17:17q23.2
not provided
NM_001100875.2(MARCH10):c.211-5694C>A single nucleotide variant Lung cancer [RCV000100594] Chr17:62765700 [GRCh38]
Chr17:60843061 [GRCh37]
Chr17:17q23.2
uncertain significance
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1
pathogenic
GRCh38/hg38 17q23.2-23.3(chr17:61631101-63219455)x1 copy number loss See cases [RCV000140458] Chr17:61631101..63219455 [GRCh38]
Chr17:59708462..61296816 [GRCh37]
Chr17:57063244..58650548 [NCBI36]
Chr17:17q23.2-23.3
likely pathogenic|uncertain significance
GRCh38/hg38 17q23.2(chr17:62039036-62927189)x3 copy number gain See cases [RCV000141715] Chr17:62039036..62927189 [GRCh38]
Chr17:60116397..61004550 [GRCh37]
Chr17:57471179..58358282 [NCBI36]
Chr17:17q23.2
likely pathogenic|uncertain significance
GRCh37/hg19 17q22-23.3(chr17:56321134-62080001)x3 copy number gain See cases [RCV000240364] Chr17:56321134..62080001 [GRCh37]
Chr17:17q22-23.3
pathogenic
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3
pathogenic
1 to 10 of 106 rows

Predicted Target Of
Summary Value
Count of predictions:2600
Count of miRNA genes:833
Interacting mature miRNAs:979
Transcripts:ENST00000311269, ENST00000456609, ENST00000544856, ENST00000578346, ENST00000579620, ENST00000580520, ENST00000582358, ENST00000582568, ENST00000583600, ENST00000583803
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597208860GWAS1304934_Hneuroticism measurement QTL GWAS1304934 (human)4e-08depressive symptom measurement176271771362717714Human
597273806GWAS1369880_Hphysical activity measurement QTL GWAS1369880 (human)9e-11wellness/fitness trait (VT:1000152)voluntary body mobility/immobility measurement (CMO:0000954)176277419862774199Human
597203265GWAS1299339_Hwellbeing measurement QTL GWAS1299339 (human)3e-08wellness/fitness trait (VT:1000152)176271771362717714Human
597323024GWAS1419098_Heducational attainment QTL GWAS1419098 (human)0.0000001educational attainment176276129262761293Human
407128938GWAS777914_Hsudden cardiac arrest QTL GWAS777914 (human)0.0000004sudden cardiac arrest176270157162701572Human

D17S794  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371760,817,253 - 60,817,484UniSTSGRCh37
GRCh371760,817,252 - 60,817,543UniSTSGRCh37
Build 361758,170,984 - 58,171,275RGDNCBI36
Celera1755,205,129 - 55,205,360UniSTS
Celera1755,205,128 - 55,205,419RGD
Cytogenetic Map17q23.2UniSTS
HuRef1756,184,206 - 56,184,437UniSTS
HuRef1756,184,205 - 56,184,496UniSTS
Marshfield Genetic Map1783.4UniSTS
Marshfield Genetic Map1783.4RGD
Genethon Genetic Map1784.2UniSTS
TNG Radiation Hybrid Map1726693.0UniSTS
deCODE Assembly Map1792.02UniSTS
Stanford-G3 RH Map172666.0UniSTS
GeneMap99-GB4 RH Map17394.04UniSTS
Whitehead-RH Map17451.6UniSTS
Whitehead-YAC Contig Map17 UniSTS
NCBI RH Map17670.6UniSTS
GeneMap99-G3 RH Map173167.0UniSTS
SHGC-84552  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371760,784,902 - 60,785,231UniSTSGRCh37
Build 361758,138,634 - 58,138,963RGDNCBI36
Celera1755,172,778 - 55,173,107RGD
Cytogenetic Map17q23.2UniSTS
HuRef1756,151,927 - 56,152,256UniSTS
TNG Radiation Hybrid Map1726684.0UniSTS
SHGC-105257  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371760,821,673 - 60,821,966UniSTSGRCh37
Build 361758,175,405 - 58,175,698RGDNCBI36
Celera1755,209,549 - 55,209,842RGD
Cytogenetic Map17q23.2UniSTS
HuRef1756,188,626 - 56,188,919UniSTS
AU048752  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17q23.2UniSTS
HuRef1756,182,785 - 56,184,407UniSTS
D17S794  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17q23.2UniSTS
TNG Radiation Hybrid Map1726693.0UniSTS
Stanford-G3 RH Map172666.0UniSTS
GeneMap99-GB4 RH Map17394.04UniSTS
NCBI RH Map17671.3UniSTS
GeneMap99-G3 RH Map173167.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1009 2224 2110 1703 4657 1189 1787 3 309 1188 155 1999 4937 4900 12 3607 757 1642 1367 163


1 to 30 of 52 rows
RefSeq Transcripts NM_001100875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_152598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011524435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011524436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011524437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008484791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_934406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 52 rows

Ensembl Acc Id: ENST00000311269   ⟹   ENSP00000311496
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,701,314 - 62,808,314 (-)Ensembl
Ensembl Acc Id: ENST00000456609   ⟹   ENSP00000416177
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,701,314 - 62,806,653 (-)Ensembl
Ensembl Acc Id: ENST00000544856   ⟹   ENSP00000443746
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,704,948 - 62,808,290 (-)Ensembl
Ensembl Acc Id: ENST00000578346
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,780,940 - 62,808,325 (-)Ensembl
Ensembl Acc Id: ENST00000579620
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,701,314 - 62,736,517 (-)Ensembl
Ensembl Acc Id: ENST00000580520   ⟹   ENSP00000464220
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,701,314 - 62,744,514 (-)Ensembl
Ensembl Acc Id: ENST00000582358
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,701,314 - 62,703,432 (-)Ensembl
Ensembl Acc Id: ENST00000582568   ⟹   ENSP00000463572
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,749,976 - 62,759,991 (-)Ensembl
Ensembl Acc Id: ENST00000583600   ⟹   ENSP00000463080
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,701,315 - 62,808,344 (-)Ensembl
Ensembl Acc Id: ENST00000583803   ⟹   ENSP00000463029
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1762,788,507 - 62,806,640 (-)Ensembl
RefSeq Acc Id: NM_001100875   ⟹   NP_001094345
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,806,640 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)RGD
Build 361758,132,407 - 58,237,743 (-)NCBI Archive
Celera1755,166,551 - 55,273,592 (-)RGD
HuRef1756,145,700 - 56,254,090 (-)NCBI
CHM1_11760,842,970 - 60,948,255 (-)NCBI
T2T-CHM13v2.01763,571,227 - 63,676,703 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001288779   ⟹   NP_001275708
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,808,314 (-)NCBI
HuRef1756,145,700 - 56,254,090 (-)NCBI
CHM1_11760,842,970 - 60,949,983 (-)NCBI
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001288780   ⟹   NP_001275709
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,704,905 - 62,808,314 (-)NCBI
HuRef1756,145,700 - 56,254,090 (-)NCBI
CHM1_11760,846,561 - 60,949,983 (-)NCBI
T2T-CHM13v2.01763,574,818 - 63,678,377 (-)NCBI
Sequence:
RefSeq Acc Id: NM_152598   ⟹   NP_689811
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,808,314 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)RGD
Build 361758,132,407 - 58,239,437 (-)NCBI Archive
Celera1755,166,551 - 55,273,592 (-)RGD
HuRef1756,145,700 - 56,254,090 (-)NCBI
CHM1_11760,842,970 - 60,949,983 (-)NCBI
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257095   ⟹   XP_005257152
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,808,314 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257096   ⟹   XP_005257153
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,806,640 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257097   ⟹   XP_005257154
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,806,640 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257098   ⟹   XP_005257155
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,808,314 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257100   ⟹   XP_005257157
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,808,314 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257102   ⟹   XP_005257159
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,808,314 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257103   ⟹   XP_005257160
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,704,905 - 62,808,314 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257106   ⟹   XP_005257163
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,795,044 (-)NCBI
GRCh371760,778,675 - 60,885,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524435   ⟹   XP_011522737
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,808,314 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524436   ⟹   XP_011522738
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,806,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524437   ⟹   XP_011522739
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,701,314 - 62,806,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054315255   ⟹   XP_054171230
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBI
RefSeq Acc Id: XM_054315256   ⟹   XP_054171231
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,676,703 (-)NCBI
RefSeq Acc Id: XM_054315257   ⟹   XP_054171232
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,676,703 (-)NCBI
RefSeq Acc Id: XM_054315258   ⟹   XP_054171233
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBI
RefSeq Acc Id: XM_054315259   ⟹   XP_054171234
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBI
RefSeq Acc Id: XM_054315260   ⟹   XP_054171235
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBI
RefSeq Acc Id: XM_054315261   ⟹   XP_054171236
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,676,703 (-)NCBI
RefSeq Acc Id: XM_054315262   ⟹   XP_054171237
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,678,377 (-)NCBI
RefSeq Acc Id: XM_054315263   ⟹   XP_054171238
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,676,703 (-)NCBI
RefSeq Acc Id: XM_054315264   ⟹   XP_054171239
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,575,409 - 63,678,377 (-)NCBI
RefSeq Acc Id: XM_054315265   ⟹   XP_054171240
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,571,227 - 63,665,107 (-)NCBI
RefSeq Acc Id: XM_054315266   ⟹   XP_054171241
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,620,036 - 63,678,377 (-)NCBI
RefSeq Acc Id: XM_054315267   ⟹   XP_054171242
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,620,036 - 63,676,703 (-)NCBI
RefSeq Acc Id: XR_008484791
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01763,581,617 - 63,678,377 (-)NCBI
RefSeq Acc Id: XR_934406
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,711,704 - 62,808,314 (-)NCBI
Sequence:
1 to 30 of 46 rows
Protein RefSeqs NP_001094345 (Get FASTA)   NCBI Sequence Viewer  
  NP_001275708 (Get FASTA)   NCBI Sequence Viewer  
  NP_001275709 (Get FASTA)   NCBI Sequence Viewer  
  NP_689811 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257152 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257153 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257154 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257155 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257157 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257159 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257160 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257163 (Get FASTA)   NCBI Sequence Viewer  
  XP_011522737 (Get FASTA)   NCBI Sequence Viewer  
  XP_011522738 (Get FASTA)   NCBI Sequence Viewer  
  XP_011522739 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171230 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171231 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171232 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171233 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171234 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171235 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171236 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171237 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171238 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171239 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171240 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171241 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171242 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH35021 (Get FASTA)   NCBI Sequence Viewer  
  AEE61238 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 46 rows
1 to 5 of 35 rows
1 to 5 of 35 rows
RefSeq Acc Id: NP_689811   ⟸   NM_152598
- Peptide Label: isoform 1
- UniProtKB: Q8IYS7 (UniProtKB/Swiss-Prot),   D3DU09 (UniProtKB/Swiss-Prot),   Q8N7Z7 (UniProtKB/Swiss-Prot),   Q8NA82 (UniProtKB/Swiss-Prot),   A0A140VKA1 (UniProtKB/TrEMBL),   B3KVK0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001094345   ⟸   NM_001100875
- Peptide Label: isoform 1
- UniProtKB: Q8IYS7 (UniProtKB/Swiss-Prot),   D3DU09 (UniProtKB/Swiss-Prot),   Q8N7Z7 (UniProtKB/Swiss-Prot),   Q8NA82 (UniProtKB/Swiss-Prot),   A0A140VKA1 (UniProtKB/TrEMBL),   B3KVK0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005257159   ⟸   XM_005257102
- Peptide Label: isoform X5
- UniProtKB: B3KVK0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005257157   ⟸   XM_005257100
- Peptide Label: isoform X4
- UniProtKB: B3KVK0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005257155   ⟸   XM_005257098
- Peptide Label: isoform X2
- UniProtKB: B3KVK0 (UniProtKB/TrEMBL)
- Sequence:
RING-CH-type

Name Modeler Protein Id AA Range Protein Structure
AF-Q8NA82-F1-model_v2 AlphaFold Q8NA82 1-808 view protein structure

RGD ID:7235933
Promoter ID:EPDNEW_H23712
Type:initiation region
Name:MARCH10_1
Description:membrane associated ring-CH-type finger 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381762,808,290 - 62,808,350EPDNEW


1 to 40 of 42 rows
Database
Acc Id
Source(s)
COSMIC MARCHF10 COSMIC
Ensembl Genes ENSG00000173838 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000311269 ENTREZGENE
  ENST00000311269.10 UniProtKB/Swiss-Prot
  ENST00000456609 ENTREZGENE
  ENST00000456609.6 UniProtKB/Swiss-Prot
  ENST00000544856 ENTREZGENE
  ENST00000580520 ENTREZGENE
  ENST00000583600 ENTREZGENE
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000173838 GTEx
HGNC ID HGNC:26655 ENTREZGENE
Human Proteome Map MARCHF10 Human Proteome Map
InterPro MARCH10_RING_CH-C4HC3 UniProtKB/Swiss-Prot
  RING-CH-type_E3_ubiq-ligase UniProtKB/Swiss-Prot
  Znf_RING-CH UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report hsa:162333 UniProtKB/Swiss-Prot
NCBI Gene 162333 ENTREZGENE
OMIM 613337 OMIM
PANTHER E3 UBIQUITIN-PROTEIN LIGASE MARCHF10-RELATED UniProtKB/Swiss-Prot
  MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER UniProtKB/Swiss-Prot
Pfam RINGv UniProtKB/Swiss-Prot
PharmGKB PA166351956 PharmGKB
PROSITE ZF_RING_CH UniProtKB/Swiss-Prot
SMART RINGv UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
UniProt A0A140VKA1 ENTREZGENE, UniProtKB/TrEMBL
  B3KVK0 ENTREZGENE, UniProtKB/TrEMBL
  D3DU09 ENTREZGENE
  G3V1Q5 ENTREZGENE, UniProtKB/TrEMBL
  J3KTK3_HUMAN UniProtKB/TrEMBL
  J3KTN9 ENTREZGENE, UniProtKB/TrEMBL
  J3QLJ2_HUMAN UniProtKB/TrEMBL
  J3QRH7 ENTREZGENE, UniProtKB/TrEMBL
  MARHA_HUMAN UniProtKB/Swiss-Prot
  Q8IYS7 ENTREZGENE
  Q8N7Z7 ENTREZGENE
  Q8NA82 ENTREZGENE
UniProt Secondary D3DU09 UniProtKB/Swiss-Prot
1 to 40 of 42 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-16 MARCHF10  membrane associated ring-CH-type finger 10  MARCH10  membrane associated ring-CH-type finger 10  Symbol and/or name change 5135510 APPROVED
2015-12-01 MARCH10  membrane associated ring-CH-type finger 10  MARCH10  membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED
2012-03-01 MARCH10  membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase  MARCH10  membrane-associated ring finger (C3HC4) 10  Symbol and/or name change 5135510 APPROVED