SERP1 (stress associated endoplasmic reticulum protein 1) - Rat Genome Database

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Gene: SERP1 (stress associated endoplasmic reticulum protein 1) Homo sapiens
Analyze
Symbol: SERP1
Name: stress associated endoplasmic reticulum protein 1
RGD ID: 1601762
HGNC Page HGNC:10759
Description: Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to act upstream of or within several processes, including positive regulation of organ growth; positive regulation of peptide hormone secretion; and positive regulation of translation. Located in cytoplasmic microtubule.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC117327; MGC133321; MGC133322; RAMP4; ribosome associated membrane protein 4; ribosome-attached membrane protein 4; stress-associated endoplasmic reticulum protein 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383150,541,998 - 150,546,496 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3150,541,998 - 150,603,228 (-)EnsemblGRCh38hg38GRCh38
GRCh373150,259,785 - 150,264,283 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363151,742,470 - 151,747,118 (-)NCBINCBI36Build 36hg18NCBI36
Celera3148,672,684 - 148,677,330 (-)NCBICelera
Cytogenetic Map3q25.1NCBI
HuRef3147,633,487 - 147,638,133 (-)NCBIHuRef
CHM1_13150,222,832 - 150,227,480 (-)NCBICHM1_1
T2T-CHM13v2.03153,293,254 - 153,297,751 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
celastrol  (EXP)
cisplatin  (EXP)
clofibric acid  (ISO)
clothianidin  (EXP)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP,ISO)
dibutyl phthalate  (ISO)
diuron  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
entinostat  (EXP)
ethanol  (ISO)
fipronil  (ISO)
folic acid  (ISO)
gedunin  (EXP)
genistein  (EXP,ISO)
glafenine  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
methapyrilene  (ISO)
methidathion  (ISO)
methylmercury chloride  (EXP)
nefazodone  (ISO)
nickel atom  (EXP)
nimesulide  (ISO)
oxidopamine  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
sodium arsenite  (EXP)
sunitinib  (EXP)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
thiram  (EXP)
Tributyltin oxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
triphenyl phosphate  (EXP)
tunicamycin  (EXP)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP)
vinclozolin  (ISO)
vorinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10601334   PMID:10931946   PMID:11076863   PMID:11230166   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15489336   PMID:16344560   PMID:16381901   PMID:19913121   PMID:20516149  
PMID:20628086   PMID:21103663   PMID:21816823   PMID:21832049   PMID:21873635   PMID:21956116   PMID:22419128   PMID:22526458   PMID:23264731   PMID:24489003   PMID:24623722   PMID:25416956  
PMID:25719802   PMID:28597972   PMID:28902358   PMID:29544880   PMID:31318583   PMID:32184288   PMID:32296183   PMID:32513696   PMID:32534478   PMID:34349018   PMID:34613934   PMID:35575683  
PMID:36417821   PMID:36949045  


Genomics

Comparative Map Data
SERP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383150,541,998 - 150,546,496 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3150,541,998 - 150,603,228 (-)EnsemblGRCh38hg38GRCh38
GRCh373150,259,785 - 150,264,283 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363151,742,470 - 151,747,118 (-)NCBINCBI36Build 36hg18NCBI36
Celera3148,672,684 - 148,677,330 (-)NCBICelera
Cytogenetic Map3q25.1NCBI
HuRef3147,633,487 - 147,638,133 (-)NCBIHuRef
CHM1_13150,222,832 - 150,227,480 (-)NCBICHM1_1
T2T-CHM13v2.03153,293,254 - 153,297,751 (-)NCBIT2T-CHM13v2.0
Serp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39358,429,390 - 58,433,305 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl358,427,238 - 58,433,313 (-)EnsemblGRCm39 Ensembl
GRCm38358,521,969 - 58,525,884 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl358,519,817 - 58,525,892 (-)EnsemblGRCm38mm10GRCm38
MGSCv37358,325,891 - 58,329,806 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36358,609,907 - 58,613,683 (-)NCBIMGSCv36mm8
Celera358,214,581 - 58,218,497 (-)NCBICelera
Cytogenetic Map3DNCBI
cM Map328.58NCBI
Serp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82144,907,204 - 144,911,187 (-)NCBIGRCr8
mRatBN7.22142,757,254 - 142,761,243 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2142,757,270 - 142,761,116 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2149,395,820 - 149,399,804 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02147,502,521 - 147,506,506 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02142,134,951 - 142,138,938 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02148,718,279 - 148,722,263 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2148,718,280 - 148,722,263 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02168,135,806 - 168,139,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42147,866,072 - 147,870,096 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12147,816,035 - 147,820,059 (-)NCBI
Celera2137,185,924 - 137,189,868 (-)NCBICelera
Cytogenetic Map2q26NCBI
Serp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554481,738,242 - 1,743,107 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554481,738,242 - 1,742,807 (-)NCBIChiLan1.0ChiLan1.0
SERP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22148,430,669 - 148,434,849 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13148,435,911 - 148,439,579 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03147,559,607 - 147,564,668 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13155,133,115 - 155,194,354 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3155,133,115 - 155,137,241 (-)Ensemblpanpan1.1panPan2
SERP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha2345,063,215 - 45,068,765 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02345,826,565 - 45,831,428 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2345,827,066 - 45,831,168 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12345,415,858 - 45,421,400 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02345,467,757 - 45,473,286 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02345,719,078 - 45,724,635 (-)NCBIUU_Cfam_GSD_1.0
SERP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1390,756,855 - 90,761,560 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11390,756,845 - 90,761,400 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21398,825,370 - 98,829,927 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SERP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11540,146,868 - 40,150,873 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1540,146,977 - 40,149,022 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604112,965,549 - 12,970,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473027,969,185 - 27,973,575 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473027,969,185 - 27,973,447 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SERP1
2 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q24-26.32(chr3:147442566-178522531)x3 copy number gain See cases [RCV000051724] Chr3:147442566..178522531 [GRCh38]
Chr3:147160353..178240319 [GRCh37]
Chr3:148643043..179723013 [NCBI36]
Chr3:3q24-26.32
pathogenic
GRCh38/hg38 3q24-29(chr3:147521892-198096565)x3 copy number gain See cases [RCV000051725] Chr3:147521892..198096565 [GRCh38]
Chr3:147239679..197823436 [GRCh37]
Chr3:148722369..199307833 [NCBI36]
Chr3:3q24-29
pathogenic
GRCh38/hg38 3q22.3-29(chr3:137126982-198110178)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|See cases [RCV000051723] Chr3:137126982..198110178 [GRCh38]
Chr3:136845824..197837049 [GRCh37]
Chr3:138328514..199321446 [NCBI36]
Chr3:3q22.3-29
pathogenic
GRCh38/hg38 3q25.1(chr3:150462960-150915627)x1 copy number loss See cases [RCV000053994] Chr3:150462960..150915627 [GRCh38]
Chr3:150180747..150633414 [GRCh37]
Chr3:151663437..152116104 [NCBI36]
Chr3:3q25.1
uncertain significance
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29
pathogenic
GRCh37/hg19 3q24-29(chr3:142995020-192997215)x4 copy number gain See cases [RCV000240256] Chr3:142995020..192997215 [GRCh37]
Chr3:3q24-29
pathogenic
GRCh37/hg19 3q24-25.2(chr3:148425748-153220169)x1 copy number loss See cases [RCV000447056] Chr3:148425748..153220169 [GRCh37]
Chr3:3q24-25.2
pathogenic
GRCh37/hg19 3q24-26.2(chr3:147180945-168415875)x1 copy number loss See cases [RCV000448130] Chr3:147180945..168415875 [GRCh37]
Chr3:3q24-26.2
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3q25.1-25.2(chr3:149404255-152786331)x1 copy number loss not provided [RCV001005477] Chr3:149404255..152786331 [GRCh37]
Chr3:3q25.1-25.2
pathogenic
GRCh37/hg19 3q24-25.1(chr3:144053029-150272658)x1 copy number loss not provided [RCV001005476] Chr3:144053029..150272658 [GRCh37]
Chr3:3q24-25.1
likely pathogenic
GRCh37/hg19 3q13.31-26.31(chr3:116620308-172042292)x3 copy number gain not provided [RCV002472621] Chr3:116620308..172042292 [GRCh37]
Chr3:3q13.31-26.31
pathogenic
GRCh37/hg19 3q22.3-26.1(chr3:138145289-162275610)x3 copy number gain See cases [RCV001194586] Chr3:138145289..162275610 [GRCh37]
Chr3:3q22.3-26.1
pathogenic
GRCh37/hg19 3q22.3-26.1(chr3:138173683-162494699) copy number gain Global developmental delay [RCV001352648] Chr3:138173683..162494699 [GRCh37]
Chr3:3q22.3-26.1
pathogenic
GRCh37/hg19 3q23-25.32(chr3:142729607-157921084)x3 copy number gain Brachycephaly [RCV001801182] Chr3:142729607..157921084 [GRCh37]
Chr3:3q23-25.32
pathogenic
GRCh37/hg19 3q24-26.1(chr3:143439359-165252122)x1 copy number loss not provided [RCV001795847] Chr3:143439359..165252122 [GRCh37]
Chr3:3q24-26.1
pathogenic
GRCh37/hg19 3q24-25.33(chr3:145486960-160504834) copy number gain not specified [RCV002053375] Chr3:145486960..160504834 [GRCh37]
Chr3:3q24-25.33
pathogenic
NC_000003.11:g.(?_148447967)_(151176497_?)del deletion Glycogen storage disease XV [RCV003120787] Chr3:148447967..151176497 [GRCh37]
Chr3:3q24-25.1
pathogenic
NM_014445.4(SERP1):c.94C>G (p.Pro32Ala) single nucleotide variant not specified [RCV004108823] Chr3:150545769 [GRCh38]
Chr3:150263556 [GRCh37]
Chr3:3q25.1
uncertain significance
NM_014445.4(SERP1):c.22C>T (p.Arg8Cys) single nucleotide variant not specified [RCV004281266] Chr3:150546114 [GRCh38]
Chr3:150263901 [GRCh37]
Chr3:3q25.1
uncertain significance
Single allele duplication not provided [RCV003448680] Chr3:140154329..197847235 [GRCh37]
Chr3:3q23-29
pathogenic
NM_014445.4(SERP1):c.189G>T (p.Arg63Ser) single nucleotide variant not specified [RCV004667129] Chr3:150544470 [GRCh38]
Chr3:150262257 [GRCh37]
Chr3:3q25.1
uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR1-1hsa-miR-1Mirtarbaseexternal_infoLuciferase reporter assay//MicroarrayFunctional MTI (WeaK)15685193
MIR204hsa-miR-204-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI21282569

Predicted Target Of
Summary Value
Count of predictions:2665
Count of miRNA genes:1035
Interacting mature miRNAs:1265
Transcripts:ENST00000239944, ENST00000463647, ENST00000479209, ENST00000484608, ENST00000487153, ENST00000490945, ENST00000491195, ENST00000491660
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300026BP36_HBlood pressure QTL 36 (human)4.04Blood pressurehypertension susceptibility3135720453161720453Human
1298415BP24_HBlood pressure QTL 24 (human)2.9Blood pressurehypertension susceptibility3135720453161720453Human

Markers in Region
G19910  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373150,260,445 - 150,260,553UniSTSGRCh37
Build 363151,743,135 - 151,743,243RGDNCBI36
Celera3148,673,349 - 148,673,457RGD
Cytogenetic Map3q25.1UniSTS
HuRef3147,634,152 - 147,634,260UniSTS
A002B48  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373150,260,445 - 150,260,553UniSTSGRCh37
Build 363151,743,135 - 151,743,243RGDNCBI36
Celera3148,673,349 - 148,673,457RGD
Cytogenetic Map3q25.1UniSTS
HuRef3147,634,152 - 147,634,260UniSTS
GeneMap99-GB4 RH Map3550.23UniSTS
NCBI RH Map31321.6UniSTS
D3S2808E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373150,261,712 - 150,261,798UniSTSGRCh37
Build 363151,744,402 - 151,744,488RGDNCBI36
Celera3148,674,615 - 148,674,701RGD
Cytogenetic Map3q25.1UniSTS
HuRef3147,635,418 - 147,635,504UniSTS
SHGC-56912  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373150,260,028 - 150,260,191UniSTSGRCh37
Build 363151,742,718 - 151,742,881RGDNCBI36
Celera3148,672,932 - 148,673,095RGD
Cytogenetic Map3q25.1UniSTS
TNG Radiation Hybrid Map384770.0UniSTS
RH15894  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373150,260,358 - 150,260,532UniSTSGRCh37
Build 363151,743,048 - 151,743,222RGDNCBI36
Celera3148,673,262 - 148,673,436RGD
Cytogenetic Map3q25.1UniSTS
HuRef3147,634,065 - 147,634,239UniSTS
GeneMap99-GB4 RH Map3548.72UniSTS
NCBI RH Map31320.4UniSTS
D3S2837E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373150,260,359 - 150,260,478UniSTSGRCh37
Build 363151,743,049 - 151,743,168RGDNCBI36
Celera3148,673,263 - 148,673,382RGD
Cytogenetic Map3q25.1UniSTS
HuRef3147,634,066 - 147,634,185UniSTS
GeneMap99-GB4 RH Map3550.33UniSTS
NCBI RH Map31318.2UniSTS
RH48541  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373150,263,313 - 150,263,453UniSTSGRCh37
Build 363151,746,003 - 151,746,143RGDNCBI36
Celera3148,676,216 - 148,676,356RGD
Cytogenetic Map3q25.1UniSTS
HuRef3147,637,019 - 147,637,159UniSTS
GeneMap99-GB4 RH Map3548.31UniSTS
NCBI RH Map31321.6UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4973 1726 2351 6 624 1951 465 2269 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_014445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA890577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB022427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC069236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC107426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF136975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK093929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK125413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL136807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC108314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR533472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB022941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ149087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X75694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000239944   ⟹   ENSP00000239944
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,541,998 - 150,546,496 (-)Ensembl
Ensembl Acc Id: ENST00000463647
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,566,385 - 150,583,155 (-)Ensembl
Ensembl Acc Id: ENST00000479209   ⟹   ENSP00000420076
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,541,998 - 150,603,174 (-)Ensembl
Ensembl Acc Id: ENST00000484608
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,566,799 - 150,603,168 (-)Ensembl
Ensembl Acc Id: ENST00000487153   ⟹   ENSP00000420002
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,544,292 - 150,546,501 (-)Ensembl
Ensembl Acc Id: ENST00000490945
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,565,796 - 150,603,228 (-)Ensembl
Ensembl Acc Id: ENST00000491195
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,546,790 - 150,603,170 (-)Ensembl
Ensembl Acc Id: ENST00000491660   ⟹   ENSP00000419472
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3150,545,397 - 150,546,499 (-)Ensembl
RefSeq Acc Id: NM_014445   ⟹   NP_055260
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383150,541,998 - 150,546,496 (-)NCBI
GRCh373150,259,780 - 150,264,428 (-)RGD
Build 363151,742,470 - 151,747,118 (-)NCBI Archive
Celera3148,672,684 - 148,677,330 (-)RGD
HuRef3147,633,487 - 147,638,133 (-)ENTREZGENE
CHM1_13150,222,832 - 150,227,480 (-)NCBI
T2T-CHM13v2.03153,293,254 - 153,297,751 (-)NCBI
Sequence:
RefSeq Acc Id: NP_055260   ⟸   NM_014445
- UniProtKB: D3DNI6 (UniProtKB/Swiss-Prot),   Q9Y6X1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000420076   ⟸   ENST00000479209
Ensembl Acc Id: ENSP00000419472   ⟸   ENST00000491660
Ensembl Acc Id: ENSP00000420002   ⟸   ENST00000487153
Ensembl Acc Id: ENSP00000239944   ⟸   ENST00000239944

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y6X1-F1-model_v2 AlphaFold Q9Y6X1 1-66 view protein structure

Promoters
RGD ID:6865986
Promoter ID:EPDNEW_H6158
Type:initiation region
Name:SERP1_1
Description:stress associated endoplasmic reticulum protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H6160  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383150,546,446 - 150,546,506EPDNEW
RGD ID:6801657
Promoter ID:HG_KWN:46465
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:UC003EXY.1
Position:
Human AssemblyChrPosition (strand)Source
Build 363151,746,906 - 151,748,067 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:10759 AgrOrtholog
COSMIC SERP1 COSMIC
Ensembl Genes ENSG00000120742 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000239944 ENTREZGENE
  ENST00000239944.7 UniProtKB/Swiss-Prot
  ENST00000479209.1 UniProtKB/Swiss-Prot
  ENST00000487153.1 UniProtKB/TrEMBL
  ENST00000491660.1 UniProtKB/TrEMBL
GTEx ENSG00000120742 GTEx
HGNC ID HGNC:10759 ENTREZGENE
Human Proteome Map SERP1 Human Proteome Map
InterPro ER_stress-assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:27230 UniProtKB/Swiss-Prot
NCBI Gene 27230 ENTREZGENE
OMIM 617674 OMIM
PANTHER PTHR15601 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RAMP4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162402942 PharmGKB
UniProt C9JSB0_HUMAN UniProtKB/TrEMBL
  C9JUH5_HUMAN UniProtKB/TrEMBL
  D3DNI6 ENTREZGENE
  Q9Y6X1 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary D3DNI6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 SERP1  stress associated endoplasmic reticulum protein 1    stress-associated endoplasmic reticulum protein 1  Symbol and/or name change 5135510 APPROVED