Tmem258l4 (transmembrane protein 258 like 4) - Rat Genome Database

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Gene: Tmem258l4 (transmembrane protein 258 like 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tmem258l4 (Ensembl: AABR07040624.1)
Name: transmembrane protein 258 like 4 (Ensembl:transmembrane protein 258 like 2)
RGD ID: 1595433
Description: Predicted to be involved in protein N-linked glycosylation. Predicted to be part of oligosaccharyltransferase complex.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC680191; similar to UPF0197 protein C11orf10 homolog; transmembrane protein 258-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X103,860,709 - 103,861,011 (-)NCBIGRCr8
mRatBN7.2X99,067,744 - 99,069,746 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX99,069,098 - 99,069,337 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X106,606,937 - 106,636,203 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X106,514,955 - 106,515,229 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X123,375,265 - 123,375,562 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmem258l4Ratprotein N-linked glycosylation involved_inIEAUniRule:UR0012307561600115GO_REF:0000104UniProtGO_REF:0000104
Tmem258l4Ratresponse to endoplasmic reticulum stress involved_inIBAMGI:1916288|PANTHER:PTN0003418751600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmem258l4Ratendoplasmic reticulum membrane is_active_inIBAFB:FBgn0036667|PANTHER:PTN000341875|UniProtKB:P611651600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmem258l4Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Tmem258l4Ratmembrane located_inIEAUniRule:UR0012307561600115GO_REF:0000104UniProtGO_REF:0000104
Tmem258l4Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Tmem258l4Ratoligosaccharyltransferase complex part_ofIEAInterPro:IPR0079151600115GO_REF:0000002InterProGO_REF:0000002
Tmem258l4Ratoligosaccharyltransferase complex part_ofIEAUniRule:UR0012307561600115GO_REF:0000104UniProtGO_REF:0000104

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmem258l4Ratoligosaccharyltransferase complex binding enablesIBAMGI:1916288|PANTHER:PTN0003418751600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Tmem258l4
4 total Variants

The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
RefSeq Transcripts XM_003752111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_063280429   ⟹   XP_063136499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X103,860,709 - 103,861,011 (-)NCBI
Protein RefSeqs XP_063136499 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070069.2
RefSeq Acc Id: XP_063136499   ⟸   XM_063280429
- UniProtKB: A0A0G2JWZ0 (UniProtKB/TrEMBL)


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 10 of 10 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-1636 BioCyc
Ensembl Genes ENSRNOG00000058183 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082858.2 UniProtKB/TrEMBL
InterPro TMEM258/Ost5 UniProtKB/TrEMBL
NCBI Gene 680191 ENTREZGENE
PANTHER UNCHARACTERIZED UniProtKB/TrEMBL
Pfam Ost5 UniProtKB/TrEMBL
PhenoGen Tmem258l4 PhenoGen
RatGTEx ENSRNOG00000058183 RatGTEx
UniProt A0A0G2JWZ0 ENTREZGENE, UniProtKB/TrEMBL
1 to 10 of 10 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-17 Tmem258l4  transmembrane protein 258 like 4  Tmem258l1  transmembrane protein 258 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Tmem258l1  transmembrane protein 258 like 1  LOC680191  similar to UPF0197 protein C11orf10 homolog  Symbol and Name Changed 1299863 APPROVED
2006-11-20 LOC680191  similar to UPF0197 protein C11orf10 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL