Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Plxdc1 | Mouse | (-)-alpha-phellandrene | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of PLXDC1 mRNA | CTD | PMID:25075043 | Plxdc1 | Mouse | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of PLXDC1 mRNA | CTD | PMID:28960355 | Plxdc1 | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PLXDC1 mRNA | CTD | PMID:22206623 | Plxdc1 | Mouse | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | Plxdc1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PLXDC1 mRNA | CTD | PMID:21570461 | Plxdc1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PLXDC1 mRNA | CTD | PMID:34747641 | Plxdc1 | Mouse | 2,4-D | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol more ... | CTD | PMID:37567420 | Plxdc1 | Mouse | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PLXDC1 mRNA | CTD | PMID:20188158 | Plxdc1 | Mouse | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of PLXDC1 mRNA | CTD | PMID:30951980 | Plxdc1 | Mouse | 6-propyl-2-thiouracil | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PLXDC1 mRNA | CTD | PMID:24780913 | Plxdc1 | Mouse | aflatoxin B1 | decreases methylation | ISO | PLXDC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PLXDC1 intron | CTD | PMID:30157460 | Plxdc1 | Mouse | Aflatoxin B2 alpha | decreases methylation | ISO | PLXDC1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of PLXDC1 intron | CTD | PMID:30157460 | Plxdc1 | Mouse | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol more ... | CTD | PMID:37567420 | Plxdc1 | Mouse | alpha-phellandrene | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of PLXDC1 mRNA | CTD | PMID:25075043 | Plxdc1 | Mouse | alpha-Zearalanol | multiple interactions | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PLXDC1 mRNA | CTD | PMID:35163327 | Plxdc1 | Mouse | antirheumatic drug | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of PLXDC1 mRNA | CTD | PMID:24449571 | Plxdc1 | Mouse | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of PLXDC1 mRNA | CTD | PMID:21569818 | Plxdc1 | Mouse | benzo[a]pyrene | decreases methylation | ISO | PLXDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PLXDC1 3' UTR and Benzo(a)pyrene results in decreased methylation of PLXDC1 promoter | CTD | PMID:27901495 | Plxdc1 | Mouse | benzo[a]pyrene | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PLXDC1 mRNA | CTD | PMID:22316170 | Plxdc1 | Mouse | bisphenol A | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PLXDC1 mRNA | CTD | PMID:25181051 more ... | Plxdc1 | Mouse | bisphenol A | increases methylation | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of PLXDC1 gene | CTD | PMID:28505145 | Plxdc1 | Mouse | bisphenol A | multiple interactions | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of PLXDC1 gene | CTD | PMID:28505145 | Plxdc1 | Mouse | bisphenol A | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PLXDC1 mRNA | CTD | PMID:27685785 | Plxdc1 | Mouse | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of PLXDC1 mRNA | CTD | PMID:29038090 | Plxdc1 | Mouse | C60 fullerene | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | fullerene C60 results in decreased expression of PLXDC1 mRNA | CTD | PMID:19167457 | Plxdc1 | Mouse | cadmium atom | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PLXDC1 mRNA | CTD | PMID:35301059 | Plxdc1 | Mouse | cadmium dichloride | decreases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of PLXDC1 mRNA | CTD | PMID:38382870 | Plxdc1 | Mouse | cadmium dichloride | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PLXDC1 mRNA | CTD | PMID:35301059 | Plxdc1 | Mouse | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Plxdc1 | Mouse | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of PLXDC1 mRNA | CTD | PMID:23125180 | Plxdc1 | Mouse | chromium(6+) | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of PLXDC1 mRNA | CTD | PMID:38479592 | Plxdc1 | Mouse | Cuprizon | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of PLXDC1 mRNA | CTD | PMID:26577399 | Plxdc1 | Mouse | D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol more ... | CTD | PMID:37567420 | Plxdc1 | Mouse | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of PLXDC1 mRNA | CTD | PMID:22733784 | Plxdc1 | Mouse | diazinon | decreases methylation | ISO | PLXDC1 (Homo sapiens) | 6480464 | Diazinon results in decreased methylation of PLXDC1 gene | CTD | PMID:22964155 | Plxdc1 | Mouse | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PLXDC1 mRNA | CTD | PMID:30529165 | Plxdc1 | Mouse | dorsomorphin | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Plxdc1 | Mouse | endosulfan | increases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of PLXDC1 mRNA | CTD | PMID:29391264 | Plxdc1 | Mouse | entinostat | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | entinostat results in increased expression of PLXDC1 mRNA | CTD | PMID:27188386 | Plxdc1 | Mouse | entinostat | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLXDC1 mRNA | CTD | PMID:27188386 | Plxdc1 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of PLXDC1 mRNA | CTD | PMID:30319688 | Plxdc1 | Mouse | ethanol | affects expression | EXP | | 6480464 | Ethanol affects the expression of PLXDC1 mRNA | CTD | PMID:30319688 | Plxdc1 | Mouse | fonofos | decreases methylation | ISO | PLXDC1 (Homo sapiens) | 6480464 | Fonofos results in decreased methylation of PLXDC1 promoter | CTD | PMID:22847954 | Plxdc1 | Mouse | fructose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol more ... | CTD | PMID:37567420 | Plxdc1 | Mouse | furan | increases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | furan results in increased expression of PLXDC1 mRNA | CTD | PMID:27387713 | Plxdc1 | Mouse | genistein | multiple interactions | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of PLXDC1 gene | CTD | PMID:28505145 | Plxdc1 | Mouse | glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol more ... | CTD | PMID:37567420 | Plxdc1 | Mouse | GW 4064 | decreases expression | EXP | | 6480464 | GW 4064 results in decreased expression of PLXDC1 mRNA | CTD | PMID:26655953 | Plxdc1 | Mouse | hydralazine | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of PLXDC1 mRNA | CTD | PMID:17183730 | Plxdc1 | Mouse | methoxychlor | affects methylation | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of PLXDC1 gene | CTD | PMID:35440735 | Plxdc1 | Mouse | methylmercury chloride | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of PLXDC1 mRNA | CTD | PMID:28001369 | Plxdc1 | Mouse | nitrofen | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | nitrofen results in decreased expression of PLXDC1 mRNA | CTD | PMID:33484710 | Plxdc1 | Mouse | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PLXDC1 mRNA | CTD | PMID:34911549 | Plxdc1 | Mouse | paracetamol | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of PLXDC1 mRNA | CTD | PMID:33387578 | Plxdc1 | Mouse | paraquat | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of PLXDC1 mRNA | CTD | PMID:32680482 | Plxdc1 | Mouse | parathion | decreases methylation | ISO | PLXDC1 (Homo sapiens) | 6480464 | Parathion results in decreased methylation of PLXDC1 promoter | CTD | PMID:22847954 | Plxdc1 | Mouse | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of PLXDC1 mRNA | CTD | PMID:37995155 | Plxdc1 | Mouse | perfluorooctanoic acid | multiple interactions | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PLXDC1 mRNA | CTD | PMID:35163327 | Plxdc1 | Mouse | progesterone | decreases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | Progesterone results in decreased expression of PLXDC1 mRNA | CTD | PMID:21795739 | Plxdc1 | Mouse | resveratrol | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | resveratrol results in increased expression of PLXDC1 mRNA | CTD | PMID:25436977 | Plxdc1 | Mouse | rotenone | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of PLXDC1 mRNA | CTD | PMID:28374803 | Plxdc1 | Mouse | SB 431542 | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Plxdc1 | Mouse | sodium arsenite | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PLXDC1 mRNA | CTD | PMID:38568856 | Plxdc1 | Mouse | succimer | multiple interactions | EXP | | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of PLXDC1 mRNA | CTD | PMID:21641980 | Plxdc1 | Mouse | terbufos | decreases methylation | ISO | PLXDC1 (Homo sapiens) | 6480464 | terbufos results in decreased methylation of PLXDC1 promoter | CTD | PMID:22847954 | Plxdc1 | Mouse | testosterone | increases expression | EXP | | 6480464 | Testosterone deficiency results in increased expression of PLXDC1 mRNA | CTD | PMID:33848595 | Plxdc1 | Mouse | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of PLXDC1 mRNA | CTD | PMID:17484886 | Plxdc1 | Mouse | thioacetamide | decreases expression | ISO | Plxdc1 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of PLXDC1 mRNA | CTD | PMID:34492290 | Plxdc1 | Mouse | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of PLXDC1 mRNA | CTD | PMID:27760801 | Plxdc1 | Mouse | titanium dioxide | increases methylation | EXP | | 6480464 | titanium dioxide results in increased methylation of PLXDC1 promoter | CTD | PMID:35295148 | Plxdc1 | Mouse | trichostatin A | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PLXDC1 mRNA | CTD | PMID:24935251 | Plxdc1 | Mouse | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of PLXDC1 mRNA | CTD | PMID:33045310 | Plxdc1 | Mouse | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of PLXDC1 mRNA | CTD | PMID:30912803 | Plxdc1 | Mouse | valproic acid | multiple interactions | ISO | PLXDC1 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of PLXDC1 mRNA more ... | CTD | PMID:17183730 and PMID:27188386 | Plxdc1 | Mouse | valproic acid | affects expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PLXDC1 mRNA | CTD | PMID:25979313 | Plxdc1 | Mouse | valproic acid | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PLXDC1 mRNA | CTD | PMID:23179753 more ... | Plxdc1 | Mouse | vorinostat | increases expression | ISO | PLXDC1 (Homo sapiens) | 6480464 | vorinostat results in increased expression of PLXDC1 mRNA | CTD | PMID:27188386 | |