Or2a5 (olfactory receptor family 2 subfamily A member 5) - Rat Genome Database

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Gene: Or2a5 (olfactory receptor family 2 subfamily A member 5) Mus musculus
Analyze
Symbol: Or2a5
Name: olfactory receptor family 2 subfamily A member 5
RGD ID: 1553880
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR2A5 (olfactory receptor family 2 subfamily A member 5).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2P3E9-4663051-4662119; MGC130305; MOR261-; MOR261-13; olfactory receptor 448; olfactory receptor MOR261-13; Olfr448
RGD Orthologs
Human
Rat
Bonobo
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39642,873,387 - 42,874,319 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl642,867,375 - 42,876,019 (+)EnsemblGRCm39 Ensembl
GRCm38642,896,453 - 42,897,385 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl642,890,441 - 42,899,085 (+)EnsemblGRCm38mm10GRCm38
MGSCv37642,846,452 - 42,847,384 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36642,826,060 - 42,826,992 (+)NCBIMGSCv36mm8
Celera642,842,797 - 42,843,729 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map620.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:16602821   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or2a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39642,873,387 - 42,874,319 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl642,867,375 - 42,876,019 (+)EnsemblGRCm39 Ensembl
GRCm38642,896,453 - 42,897,385 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl642,890,441 - 42,899,085 (+)EnsemblGRCm38mm10GRCm38
MGSCv37642,846,452 - 42,847,384 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36642,826,060 - 42,826,992 (+)NCBIMGSCv36mm8
Celera642,842,797 - 42,843,729 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map620.96NCBI
OR2A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387144,048,948 - 144,058,845 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7144,048,948 - 144,058,845 (+)EnsemblGRCh38hg38GRCh38
GRCh377143,746,041 - 143,755,938 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367143,378,428 - 143,379,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 347143,185,142 - 143,186,078NCBI
Celera7138,380,756 - 138,381,691 (+)NCBICelera
Cytogenetic Map7q35NCBI
HuRef7137,947,020 - 137,947,955 (+)NCBIHuRef
CHM1_17143,684,862 - 143,685,797 (+)NCBICHM1_1
T2T-CHM13v2.07145,329,435 - 145,339,332 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27143,085,710 - 143,086,645 (+)NCBI
Or2a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8472,856,094 - 72,857,026 (+)NCBIGRCr8
mRatBN7.2471,856,084 - 71,857,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl471,853,931 - 71,858,347 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_WKY_Bbb_1.0471,149,204 - 71,150,136 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0472,480,540 - 72,481,472 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl472,480,540 - 72,481,472 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04137,178,372 - 137,179,304 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4470,795,367 - 70,796,299 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1471,071,496 - 71,072,429 (+)NCBI
Celera466,805,791 - 66,806,723 (+)NCBICelera
Cytogenetic Map4q24NCBI
LOC100977815
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26180,761,492 - 180,770,476 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1732,776,522 - 32,777,457 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07135,907,481 - 135,908,506 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17148,396,699 - 148,397,699 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7148,396,727 - 148,397,662 (+)Ensemblpanpan1.1panPan2
OR2A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,842,189 - 5,843,121 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,842,189 - 5,843,121 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha166,889,741 - 6,890,673 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0165,696,040 - 5,696,972 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl165,696,040 - 5,696,972 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1165,635,960 - 5,636,892 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,493,816 - 5,494,748 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0165,563,365 - 5,564,298 (-)NCBIUU_Cfam_GSD_1.0
LOC103227151
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121112,786,666 - 112,791,526 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660729,538,621 - 9,560,234 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:44
Interacting mature miRNAs:44
Transcripts:ENSMUST00000058668
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse

Markers in Region
UniSTS:485062  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38642,896,453 - 42,897,385UniSTSGRCm38
MGSCv37642,846,452 - 42,847,384UniSTSGRCm37
Celera642,842,797 - 42,843,729UniSTS
Cytogenetic Map6B2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000058668   ⟹   ENSMUSP00000059195
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl642,873,387 - 42,874,319 (+)Ensembl
GRCm38.p6 Ensembl642,896,453 - 42,897,385 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213952   ⟹   ENSMUSP00000150419
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl642,867,662 - 42,876,019 (+)Ensembl
GRCm38.p6 Ensembl642,890,728 - 42,899,085 (+)Ensembl
Ensembl Acc Id: ENSMUST00000214529   ⟹   ENSMUSP00000148884
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl642,867,375 - 42,876,019 (+)Ensembl
GRCm38.p6 Ensembl642,890,441 - 42,899,085 (+)Ensembl
RefSeq Acc Id: NM_146273   ⟹   NP_666385
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39642,873,387 - 42,874,319 (+)NCBI
GRCm38642,896,453 - 42,897,385 (+)ENTREZGENE
MGSCv37642,846,452 - 42,847,384 (+)RGD
Celera642,842,797 - 42,843,729 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_666385   ⟸   NM_146273
- UniProtKB: Q8VES9 (UniProtKB/TrEMBL),   Q3B7Z1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000150419   ⟸   ENSMUST00000213952
Ensembl Acc Id: ENSMUSP00000059195   ⟸   ENSMUST00000058668
Ensembl Acc Id: ENSMUSP00000148884   ⟸   ENSMUST00000214529
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VES9-F1-model_v2 AlphaFold Q8VES9 1-310 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030282 AgrOrtholog
Ensembl Genes ENSMUSG00000043119 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000058668 ENTREZGENE
  ENSMUST00000058668.4 UniProtKB/TrEMBL
  ENSMUST00000213952.3 UniProtKB/TrEMBL
  ENSMUST00000214529.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258270 UniProtKB/TrEMBL
MGD MGI:3030282 ENTREZGENE
NCBI Gene 258270 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 2A5 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2a5 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q3B7Z1 ENTREZGENE, UniProtKB/TrEMBL
  Q8VES9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or2a5  olfactory receptor family 2 subfamily A member 5  Olfr448  olfactory receptor 448  Symbol and/or name change 5135510 APPROVED