Or5ap2 (olfactory receptor family 5 subfamily AP member 2) - Rat Genome Database

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Gene: Or5ap2 (olfactory receptor family 5 subfamily AP member 2) Mus musculus
Analyze
Symbol: Or5ap2
Name: olfactory receptor family 5 subfamily AP member 2
RGD ID: 1553538
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Orthologous to human OR5AP2 (olfactory receptor family 5 subfamily AP member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2Q125-47327964-47328917; MOR201; MOR201-2; olfactory receptor 1020; olfactory receptor 201-2; olfactory receptor 5AP2; olfactory receptor MOR201-2; Olfr1020
RGD Orthologs
Human
Rat
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39285,679,764 - 85,680,842 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl285,677,374 - 85,682,138 (+)EnsemblGRCm39 Ensembl
GRCm38285,849,420 - 85,850,498 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl285,847,030 - 85,851,794 (+)EnsemblGRCm38mm10GRCm38
MGSCv37285,689,577 - 85,690,655 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36285,650,293 - 85,651,246 (+)NCBIMGSCv36mm8
Celera287,432,636 - 87,433,714 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or5ap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39285,679,764 - 85,680,842 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl285,677,374 - 85,682,138 (+)EnsemblGRCm39 Ensembl
GRCm38285,849,420 - 85,850,498 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl285,847,030 - 85,851,794 (+)EnsemblGRCm38mm10GRCm38
MGSCv37285,689,577 - 85,690,655 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36285,650,293 - 85,651,246 (+)NCBIMGSCv36mm8
Celera287,432,636 - 87,433,714 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.68NCBI
OR5AP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,641,489 - 56,642,439 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,641,489 - 56,642,439 (-)EnsemblGRCh38hg38GRCh38
GRCh371156,408,965 - 56,409,915 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,165,541 - 56,166,491 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,165,540 - 56,166,491NCBI
Celera1153,756,649 - 53,757,599 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1152,746,384 - 52,747,334 (-)NCBIHuRef
CHM1_11156,275,227 - 56,276,177 (-)NCBICHM1_1
T2T-CHM13v2.01156,579,476 - 56,580,426 (-)NCBIT2T-CHM13v2.0
Or5ap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8391,324,160 - 91,325,113 (+)NCBIGRCr8
mRatBN7.2370,917,491 - 70,918,444 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl370,914,231 - 70,919,218 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx374,311,969 - 74,312,922 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0382,910,495 - 82,911,448 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0380,686,114 - 80,687,067 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0373,235,594 - 73,236,547 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl373,235,594 - 73,236,547 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0379,804,150 - 79,805,103 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4369,097,837 - 69,098,790 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1368,994,208 - 68,995,162 (+)NCBI
Celera370,249,881 - 70,250,834 (+)NCBICelera
Cytogenetic Map3q24NCBI
OR5AP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11839,349,882 - 39,350,835 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1839,349,885 - 39,350,835 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,895,242 - 38,896,195 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01840,030,112 - 40,031,065 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1840,030,115 - 40,031,065 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11839,632,378 - 39,633,331 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01839,199,452 - 39,200,405 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01839,782,107 - 39,783,060 (+)NCBIUU_Cfam_GSD_1.0
LOC100518174
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2214,116,162 - 14,117,115 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC119624250
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl116,394,225 - 16,396,724 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038113,719,607 - 113,720,606 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Or5ap2
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:41
Interacting mature miRNAs:41
Transcripts:ENSMUST00000055840
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25170327685703425Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse

Markers in Region
UniSTS:495416  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38285,849,420 - 85,850,498UniSTSGRCm38
MGSCv37285,689,577 - 85,690,655UniSTSGRCm37
Celera287,432,636 - 87,433,714UniSTS
Cytogenetic Map2E1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000055840   ⟹   ENSMUSP00000058242
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl285,679,764 - 85,680,842 (+)Ensembl
GRCm38.p6 Ensembl285,849,420 - 85,850,498 (+)Ensembl
Ensembl Acc Id: ENSMUST00000215347   ⟹   ENSMUSP00000150285
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl285,677,374 - 85,682,138 (+)Ensembl
GRCm38.p6 Ensembl285,847,030 - 85,851,794 (+)Ensembl
RefSeq Acc Id: NM_146580   ⟹   NP_666791
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39285,679,764 - 85,680,842 (+)NCBI
GRCm38285,849,420 - 85,850,498 (+)ENTREZGENE
MGSCv37285,689,577 - 85,690,655 (+)RGD
Celera287,432,636 - 87,433,714 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_666791   ⟸   NM_146580
- UniProtKB: Q8VFK7 (UniProtKB/Swiss-Prot),   Q0VEQ7 (UniProtKB/TrEMBL),   A0A1L1STE7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000058242   ⟸   ENSMUST00000055840
Ensembl Acc Id: ENSMUSP00000150285   ⟸   ENSMUST00000215347

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VFK7-F1-model_v2 AlphaFold Q8VFK7 1-317 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030854 AgrOrtholog
Ensembl Genes ENSMUSG00000046975 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000055840 ENTREZGENE
  ENSMUST00000055840.7 UniProtKB/Swiss-Prot
  ENSMUST00000215347.3 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Olfact_rcpt UniProtKB/Swiss-Prot
KEGG Report mmu:258573 UniProtKB/Swiss-Prot
MGD MGI:3030854 ENTREZGENE
NCBI Gene 258573 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_4 UniProtKB/Swiss-Prot
PhenoGen Or5ap2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  OLFACTORYR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0A1L1STE7 ENTREZGENE
  O1020_MOUSE UniProtKB/Swiss-Prot
  Q0VEQ7 ENTREZGENE
  Q8VFK7 ENTREZGENE
UniProt Secondary A0A1L1STE7 UniProtKB/Swiss-Prot
  Q0VEQ7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or5ap2  olfactory receptor family 5 subfamily AP member 2  Olfr1020  olfactory receptor 1020  Symbol and/or name change 5135510 APPROVED