Or56a4 (olfactory receptor family 56 subfamily A member 4) - Rat Genome Database

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Gene: Or56a4 (olfactory receptor family 56 subfamily A member 4) Mus musculus
Analyze
Symbol: Or56a4
Name: olfactory receptor family 56 subfamily A member 4
RGD ID: 1553012
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR56A4 (olfactory receptor family 56 subfamily A member 4).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2PBJ9-7786441-7785503; MOR40; MOR40-8P; olfactory receptor 684; olfactory receptor GA_x6K02T2PBJ9-7786441-7785503; Olfr684
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397104,805,949 - 104,806,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7104,803,899 - 104,812,860 (-)EnsemblGRCm39 Ensembl
GRCm387105,156,742 - 105,157,680 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,154,692 - 105,163,653 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,305,256 - 112,306,194 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367105,030,563 - 105,031,501 (-)NCBIMGSCv36mm8
Celera7105,431,807 - 105,432,745 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:12477932   PMID:14611657   PMID:21267068   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or56a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397104,805,949 - 104,806,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7104,803,899 - 104,812,860 (-)EnsemblGRCm39 Ensembl
GRCm387105,156,742 - 105,157,680 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,154,692 - 105,163,653 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,305,256 - 112,306,194 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367105,030,563 - 105,031,501 (-)NCBIMGSCv36mm8
Celera7105,431,807 - 105,432,745 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.77NCBI
OR56A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,999,445 - 6,006,946 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,999,445 - 6,006,946 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,020,675 - 6,028,176 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,979,857 - 5,980,954 (-)NCBINCBI36Build 36hg18NCBI36
Build 34115,979,856 - 5,980,954NCBI
Celera116,142,864 - 6,143,961 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef115,683,345 - 5,684,442 (-)NCBIHuRef
CHM1_1116,022,494 - 6,023,591 (-)NCBICHM1_1
T2T-CHM13v2.0116,057,948 - 6,065,449 (-)NCBIT2T-CHM13v2.0
Or56a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81168,912,530 - 168,913,468 (-)NCBIGRCr8
mRatBN7.21159,500,672 - 159,501,610 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1159,500,672 - 159,501,610 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1167,518,023 - 167,518,961 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01174,704,003 - 174,704,941 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01167,591,656 - 167,592,594 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,990,693 - 169,991,631 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01177,005,303 - 177,006,241 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41162,881,818 - 162,882,756 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11162,977,294 - 162,978,233 (-)NCBI
Celera1157,440,365 - 157,441,303 (-)NCBICelera
Cytogenetic Map1q32NCBI
LOC100989488
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v298,437,054 - 8,444,549 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1118,400,952 - 8,408,447 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,135,566 - 6,136,762 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,816,805 - 5,818,001 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,816,864 - 5,817,961 (-)Ensemblpanpan1.1panPan2
OR56A4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,315,080 - 29,316,523 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,315,471 - 29,316,412 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,006,434 - 29,018,235 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02130,130,308 - 30,141,858 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12129,453,126 - 29,464,663 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02129,619,175 - 29,630,779 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02129,809,961 - 29,823,836 (-)NCBIUU_Cfam_GSD_1.0
LOC110262266
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.193,885,910 - 3,887,115 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103241655
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1158,772,635 - 58,778,929 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl158,772,946 - 58,773,887 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038156,631,260 - 156,632,453 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Or56a4
27 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:34
Interacting mature miRNAs:36
Transcripts:ENSMUST00000060893
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)787849208108099207Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
13464255Ifvrq2_minfluenza virus resistance QTL 2 (mouse)792500698106455693Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse

Markers in Region
UniSTS:491973  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387105,156,715 - 105,157,719UniSTSGRCm38
MGSCv377112,305,229 - 112,306,233UniSTSGRCm37
Celera7105,431,780 - 105,432,784UniSTS
Cytogenetic Map7E3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000060893   ⟹   ENSMUSP00000055880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7104,805,949 - 104,806,887 (-)Ensembl
GRCm38.p6 Ensembl7105,156,742 - 105,157,680 (-)Ensembl
Ensembl Acc Id: ENSMUST00000215552   ⟹   ENSMUSP00000149627
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7104,803,899 - 104,812,698 (-)Ensembl
GRCm38.p6 Ensembl7105,154,692 - 105,163,491 (-)Ensembl
Ensembl Acc Id: ENSMUST00000215744   ⟹   ENSMUSP00000149904
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7104,803,899 - 104,812,791 (-)Ensembl
GRCm38.p6 Ensembl7105,154,692 - 105,163,584 (-)Ensembl
Ensembl Acc Id: ENSMUST00000217136   ⟹   ENSMUSP00000150107
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7104,803,899 - 104,812,860 (-)Ensembl
GRCm38.p6 Ensembl7105,154,692 - 105,163,653 (-)Ensembl
RefSeq Acc Id: NM_207249   ⟹   NP_997132
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397104,805,949 - 104,806,887 (-)NCBI
GRCm387105,156,742 - 105,157,680 (-)ENTREZGENE
MGSCv377112,305,256 - 112,306,194 (-)RGD
Celera7105,431,807 - 105,432,745 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_997132 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI20637 (Get FASTA)   NCBI Sequence Viewer  
  AAI20639 (Get FASTA)   NCBI Sequence Viewer  
  AAP71151 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000055880
  ENSMUSP00000055880.5
  ENSMUSP00000149627.2
  ENSMUSP00000149904.2
  ENSMUSP00000150107.2
RefSeq Acc Id: NP_997132   ⟸   NM_207249
- UniProtKB: Q7TRN8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000150107   ⟸   ENSMUST00000217136
Ensembl Acc Id: ENSMUSP00000055880   ⟸   ENSMUST00000060893
Ensembl Acc Id: ENSMUSP00000149904   ⟸   ENSMUST00000215744
Ensembl Acc Id: ENSMUSP00000149627   ⟸   ENSMUST00000215552
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TRN8-F1-model_v2 AlphaFold Q7TRN8 1-312 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030518 AgrOrtholog
Ensembl Genes ENSMUSG00000047225 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000060893 ENTREZGENE
  ENSMUST00000060893.7 UniProtKB/TrEMBL
  ENSMUST00000215552.2 UniProtKB/TrEMBL
  ENSMUST00000215744.2 UniProtKB/TrEMBL
  ENSMUST00000217136.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_rcpt UniProtKB/TrEMBL
KEGG Report mmu:244187 UniProtKB/TrEMBL
MGD MGI:3030518 ENTREZGENE
NCBI Gene 244187 ENTREZGENE
PANTHER OLFACTORY RECEPTOR 56A4 UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 56B1-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or56a4 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TRN8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or56a4  olfactory receptor family 56 subfamily A member 4  Olfr684  olfactory receptor 684  Symbol and/or name change 5135510 APPROVED