Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | ISO | KRT33B (Homo sapiens) | 6480464 | Estradiol promotes the reaction [KRT33B protein binds to ESR1 protein] | CTD | PMID:27156127 | 2-hydroxypropanoic acid | decreases expression | ISO | KRT33B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KRT33B mRNA | CTD | PMID:30851411 | antirheumatic drug | increases expression | ISO | KRT33B (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of KRT33B mRNA | CTD | PMID:24449571 | benzo[a]pyrene | increases methylation | ISO | KRT33B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of KRT33B 3' UTR more ... | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | KRT33B (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of KRT33B mRNA | CTD | PMID:31163220 | CGP 52608 | multiple interactions | ISO | KRT33B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KRT33B gene] | CTD | PMID:28238834 | clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of KRT33B mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of KRT33B mRNA] | CTD | PMID:17585979 | crocidolite asbestos | increases expression | ISO | KRT33B (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of KRT33B mRNA | CTD | PMID:25351596 | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of KRT33B mRNA | CTD | PMID:35436446 | folic acid | decreases expression | ISO | KRT33B (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of KRT33B mRNA | CTD | PMID:21867686 | methylisothiazolinone | increases expression | ISO | KRT33B (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of KRT33B mRNA | CTD | PMID:31629900 | N-methyl-4-phenylpyridinium | increases expression | ISO | KRT33B (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of KRT33B mRNA | CTD | PMID:24810058 | paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of KRT33B mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of KRT33B mRNA] | CTD | PMID:17585979 | potassium chromate | increases expression | ISO | KRT33B (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of KRT33B mRNA | CTD | PMID:22714537 | rac-lactic acid | decreases expression | ISO | KRT33B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KRT33B mRNA | CTD | PMID:30851411 | silicon dioxide | increases expression | ISO | KRT33B (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of KRT33B mRNA | CTD | PMID:25351596 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| You must be logged in to use this feature |
| {{ loginError }} |
|
|
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Gene-Chemical Interaction Annotations
Click to see Annotation Detail View
|
|
|
Phenotype Annotations
Click to see Annotation Detail View
Mammalian Phenotype
|
|
|
References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Differential expression of type I hair keratins. | Bertolino AP, etal., J Invest Dermatol 1990 Mar;94(3):297-303. |
| 2. | The RAIG family member, GPRC5D, is associated with hard-keratinized structures. | Inoue S, etal., J Invest Dermatol 2004 Mar;122(3):565-73. |
| 3. | Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation. | Meier N, etal., Mech Dev 1999 Dec;89(1-2):215-21. |
| 4. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 5. | BAC contig from a 3-cM region of mouse chromosome 11 surrounding Brca1. | Pershouse M, etal., Genomics 2000 Oct 1;69(1):139-42. |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 7. | Database resources of the National Center for Biotechnology Information. | Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6. |
| 8. | Sequence and expression of murine type I hair keratins mHa2 and mHa3. | Winter H, etal., Exp Cell Res 1994 Jun;212(2):190-200. |
Additional References at PubMed
| PMID:16831889 | PMID:21267068 | PMID:21565611 | PMID:21873635 | PMID:28964716 |
Genomics
Comparative Map Data
| Krt33b (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| KRT33B (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| LOC100516036 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| LOC103243461 (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Variants
.
Variants in Krt33b
209 total Variants 
|
