KRT33A (keratin 33A) - Rat Genome Database

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Gene: KRT33A (keratin 33A) Homo sapiens
Analyze
Symbol: KRT33A
Name: keratin 33A
RGD ID: 1314759
HGNC Page HGNC:6450
Description: Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Located in extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Ha-3I; HA3I; hair keratin, type I Ha3-I; hard keratin, type I,3I; hHa3-I; K33A; keratin 33A, type I; keratin, hair, acidic, 3A; keratin, type I cuticular Ha3-I; keratin-33A; Krt1-3; KRTHA3A
RGD Orthologs
Mouse
Rat
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,346,092 - 41,350,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,346,092 - 41,350,828 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,502,344 - 39,507,080 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,755,897 - 36,760,582 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,755,896 - 36,760,582NCBI
Celera1736,155,587 - 36,160,272 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,265,846 - 35,270,566 (-)NCBIHuRef
CHM1_11739,737,689 - 39,742,409 (-)NCBICHM1_1
T2T-CHM13v2.01742,201,624 - 42,206,360 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7565656   PMID:7686952   PMID:9756910   PMID:10391933   PMID:12477932   PMID:15617563   PMID:16831889   PMID:17353931   PMID:21873635   PMID:23580065   PMID:25324306   PMID:26618866  
PMID:28515276   PMID:33838681   PMID:35864588  


Genomics

Comparative Map Data
KRT33A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,346,092 - 41,350,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,346,092 - 41,350,828 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,502,344 - 39,507,080 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,755,897 - 36,760,582 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,755,896 - 36,760,582NCBI
Celera1736,155,587 - 36,160,272 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,265,846 - 35,270,566 (-)NCBIHuRef
CHM1_11739,737,689 - 39,742,409 (-)NCBICHM1_1
T2T-CHM13v2.01742,201,624 - 42,206,360 (-)NCBIT2T-CHM13v2.0
Krt33a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,902,025 - 99,907,038 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,902,021 - 99,907,038 (-)EnsemblGRCm39 Ensembl
GRCm3811100,011,199 - 100,016,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,011,195 - 100,016,212 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,872,513 - 99,877,526 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361199,827,292 - 99,832,302 (-)NCBIMGSCv36mm8
Celera11110,627,526 - 110,632,533 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.35NCBI
Krt33a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81085,442,988 - 85,447,947 (-)NCBIGRCr8
mRatBN7.21084,942,584 - 84,947,544 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1084,942,573 - 84,947,478 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1089,961,352 - 89,965,835 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01089,459,499 - 89,463,982 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01084,851,464 - 84,855,947 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
RGSC_v3.41088,941,299 - 88,945,785 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1083,662,311 - 83,666,797 (-)NCBICelera
Cytogenetic Map10q31NCBI
KRT33A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,413,472 - 21,418,494 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,413,472 - 21,418,494 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,875,217 - 20,880,239 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0922,134,481 - 22,139,503 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1920,920,389 - 20,925,411 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0921,186,406 - 21,191,428 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,290,215 - 21,295,237 (+)NCBIUU_Cfam_GSD_1.0
LOC101956833
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560220,757,184 - 20,781,165 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493649016,294,365 - 16,299,268 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT33A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11221,250,439 - 21,255,565 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,363,117 - 21,368,238 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in KRT33A
40 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3		 pathogenic
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2		 pathogenic
GRCh38/hg38 17q12-21.31(chr17:39199873-45629579)x3 copy number gain See cases [RCV000052479] Chr17:39199873..45629579 [GRCh38]
Chr17:37356126..43706945 [GRCh37]
Chr17:34609652..41062728 [NCBI36]
Chr17:17q12-21.31		 pathogenic
NM_004138.3(KRT33A):c.264C>T (p.Ile88=) single nucleotide variant Malignant melanoma [RCV000071466] Chr17:41350504 [GRCh38]
Chr17:39506756 [GRCh37]
Chr17:36760282 [NCBI36]
Chr17:17q21.2		 not provided
NM_004138.4(KRT33A):c.215A>G (p.Glu72Gly) single nucleotide variant Malignant tumor of prostate [RCV000149156] Chr17:41350553 [GRCh38]
Chr17:39506805 [GRCh37]
Chr17:17q21.2		 uncertain significance
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_004138.4(KRT33A):c.623G>A (p.Arg208His) single nucleotide variant Inborn genetic diseases [RCV003240719] Chr17:41347188 [GRCh38]
Chr17:39503440 [GRCh37]
Chr17:17q21.2		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q21.2(chr17:39502398-39527866)x1 copy number loss not provided [RCV000739513] Chr17:39502398..39527866 [GRCh37]
Chr17:17q21.2		 benign
GRCh37/hg19 17q21.2(chr17:39502409-39531402)x1 copy number loss not provided [RCV000739514] Chr17:39502409..39531402 [GRCh37]
Chr17:17q21.2		 benign
NM_004138.4(KRT33A):c.1040C>A (p.Ala347Glu) single nucleotide variant Inborn genetic diseases [RCV003198008] Chr17:41346505 [GRCh38]
Chr17:39502757 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.916C>T (p.Arg306Cys) single nucleotide variant Inborn genetic diseases [RCV002729597] Chr17:41346629 [GRCh38]
Chr17:39502881 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.448T>G (p.Ser150Ala) single nucleotide variant Inborn genetic diseases [RCV002818789] Chr17:41348623 [GRCh38]
Chr17:39504875 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.998A>G (p.Glu333Gly) single nucleotide variant Inborn genetic diseases [RCV002864621] Chr17:41346547 [GRCh38]
Chr17:39502799 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.622C>T (p.Arg208Cys) single nucleotide variant Inborn genetic diseases [RCV002992350] Chr17:41347189 [GRCh38]
Chr17:39503441 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.245C>T (p.Ala82Val) single nucleotide variant Inborn genetic diseases [RCV002688533] Chr17:41350523 [GRCh38]
Chr17:39506775 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.53C>T (p.Ser18Phe) single nucleotide variant Inborn genetic diseases [RCV002684132] Chr17:41350715 [GRCh38]
Chr17:39506967 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.1178G>A (p.Arg393His) single nucleotide variant Inborn genetic diseases [RCV003000832] Chr17:41346156 [GRCh38]
Chr17:39502408 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.659A>G (p.Asp220Gly) single nucleotide variant Inborn genetic diseases [RCV002978906] Chr17:41347152 [GRCh38]
Chr17:39503404 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.1183C>T (p.Arg395Trp) single nucleotide variant Inborn genetic diseases [RCV002823336] Chr17:41346151 [GRCh38]
Chr17:39502403 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.31A>G (p.Ser11Gly) single nucleotide variant Inborn genetic diseases [RCV002823337] Chr17:41350737 [GRCh38]
Chr17:39506989 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.689G>A (p.Ser230Asn) single nucleotide variant Inborn genetic diseases [RCV002662285] Chr17:41347122 [GRCh38]
Chr17:39503374 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.134A>G (p.Asn45Ser) single nucleotide variant Inborn genetic diseases [RCV002888578] Chr17:41350634 [GRCh38]
Chr17:39506886 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.1126A>G (p.Asn376Asp) single nucleotide variant Inborn genetic diseases [RCV002783943] Chr17:41346208 [GRCh38]
Chr17:39502460 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.835G>A (p.Val279Ile) single nucleotide variant Inborn genetic diseases [RCV002767451] Chr17:41346885 [GRCh38]
Chr17:39503137 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.224G>A (p.Arg75His) single nucleotide variant Inborn genetic diseases [RCV002768715] Chr17:41350544 [GRCh38]
Chr17:39506796 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.555G>C (p.Glu185Asp) single nucleotide variant Inborn genetic diseases [RCV002768453] Chr17:41348516 [GRCh38]
Chr17:39504768 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.488G>T (p.Arg163Leu) single nucleotide variant Inborn genetic diseases [RCV002697142] Chr17:41348583 [GRCh38]
Chr17:39504835 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.454C>T (p.Arg152Trp) single nucleotide variant Inborn genetic diseases [RCV003006588] Chr17:41348617 [GRCh38]
Chr17:39504869 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.745A>C (p.Thr249Pro) single nucleotide variant Inborn genetic diseases [RCV002763745] Chr17:41347066 [GRCh38]
Chr17:39503318 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.141C>G (p.Phe47Leu) single nucleotide variant Inborn genetic diseases [RCV002981829] Chr17:41350627 [GRCh38]
Chr17:39506879 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.1090G>A (p.Asp364Asn) single nucleotide variant Inborn genetic diseases [RCV002803456] Chr17:41346455 [GRCh38]
Chr17:39502707 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.719G>A (p.Arg240His) single nucleotide variant Inborn genetic diseases [RCV002986349] Chr17:41347092 [GRCh38]
Chr17:39503344 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.127A>G (p.Asn43Asp) single nucleotide variant Inborn genetic diseases [RCV002989186] Chr17:41350641 [GRCh38]
Chr17:39506893 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.427A>G (p.Thr143Ala) single nucleotide variant Inborn genetic diseases [RCV002673687] Chr17:41349350 [GRCh38]
Chr17:39505602 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.479A>G (p.Asn160Ser) single nucleotide variant Inborn genetic diseases [RCV002988202] Chr17:41348592 [GRCh38]
Chr17:39504844 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.757G>A (p.Glu253Lys) single nucleotide variant Inborn genetic diseases [RCV003214699] Chr17:41346963 [GRCh38]
Chr17:39503215 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.1109A>G (p.Asn370Ser) single nucleotide variant Inborn genetic diseases [RCV003260968] Chr17:41346225 [GRCh38]
Chr17:39502477 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.1033G>A (p.Val345Met) single nucleotide variant Inborn genetic diseases [RCV003183589] Chr17:41346512 [GRCh38]
Chr17:39502764 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.82G>A (p.Gly28Ser) single nucleotide variant Inborn genetic diseases [RCV003190276] Chr17:41350686 [GRCh38]
Chr17:39506938 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.938A>G (p.Gln313Arg) single nucleotide variant Inborn genetic diseases [RCV003173243] Chr17:41346607 [GRCh38]
Chr17:39502859 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.853G>A (p.Glu285Lys) single nucleotide variant Inborn genetic diseases [RCV003265571] Chr17:41346867 [GRCh38]
Chr17:39503119 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.1086C>A (p.Ser362Arg) single nucleotide variant Inborn genetic diseases [RCV003344982] Chr17:41346459 [GRCh38]
Chr17:39502711 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.986G>T (p.Arg329Leu) single nucleotide variant Inborn genetic diseases [RCV003346864] Chr17:41346559 [GRCh38]
Chr17:39502811 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.389A>G (p.Gln130Arg) single nucleotide variant Inborn genetic diseases [RCV003347135] Chr17:41349388 [GRCh38]
Chr17:39505640 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.229C>G (p.Leu77Val) single nucleotide variant Inborn genetic diseases [RCV003375998] Chr17:41350539 [GRCh38]
Chr17:39506791 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_004138.4(KRT33A):c.878G>A (p.Arg293Gln) single nucleotide variant Inborn genetic diseases [RCV003344633] Chr17:41346667 [GRCh38]
Chr17:39502919 [GRCh37]
Chr17:17q21.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:205
Count of miRNA genes:193
Interacting mature miRNAs:203
Transcripts:ENST00000007735
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH103983  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371739,502,020 - 39,502,205UniSTSGRCh37
Build 361736,755,546 - 36,755,731RGDNCBI36
Celera1736,155,236 - 36,155,421RGD
Cytogenetic Map17q12-q21UniSTS
HuRef1735,265,522 - 35,265,707UniSTS
GeneMap99-GB4 RH Map17306.52UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 12 1
Medium 1 164 1 30 3 1 3 71
Low 11 11 7 33 4 1 146 8 24 23 428 35 34 3 79 1
Below cutoff 498 582 277 151 244 51 1294 481 1512 84 244 253 106 257 833 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000007735   ⟹   ENSP00000007735
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1741,346,092 - 41,350,828 (-)Ensembl
RefSeq Acc Id: NM_004138   ⟹   NP_004129
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,346,092 - 41,350,828 (-)NCBI
GRCh371739,502,344 - 39,507,064 (-)NCBI
Build 361736,755,897 - 36,760,582 (-)NCBI Archive
Celera1736,155,587 - 36,160,272 (-)RGD
HuRef1735,265,846 - 35,270,566 (-)NCBI
CHM1_11739,737,689 - 39,742,409 (-)NCBI
T2T-CHM13v2.01742,201,624 - 42,206,360 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524786   ⟹   XP_011523088
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,346,092 - 41,348,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054316025   ⟹   XP_054172000
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01742,201,624 - 42,203,562 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_004129   ⟸   NM_004138
- UniProtKB: Q6NTB9 (UniProtKB/Swiss-Prot),   B2RA87 (UniProtKB/Swiss-Prot),   Q6ZZB9 (UniProtKB/Swiss-Prot),   O76009 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011523088   ⟸   XM_011524786
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000007735   ⟸   ENST00000007735
RefSeq Acc Id: XP_054172000   ⟸   XM_054316025
- Peptide Label: isoform X1
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O76009-F1-model_v2 AlphaFold O76009 1-404 view protein structure

Promoters
RGD ID:7234969
Promoter ID:EPDNEW_H23230
Type:multiple initiation site
Name:KRT33A_1
Description:keratin 33A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,350,743 - 41,350,803EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6450 AgrOrtholog
COSMIC KRT33A COSMIC
Ensembl Genes ENSG00000006059 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000261986 UniProtKB/Swiss-Prot
  ENSG00000292027 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000007735 ENTREZGENE
  ENST00000007735.4 UniProtKB/Swiss-Prot
  ENST00000576236.1 UniProtKB/Swiss-Prot
  ENST00000709590.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
  Single helix bin UniProtKB/Swiss-Prot
  Vasodilator-stimulated phosphoprotein UniProtKB/Swiss-Prot
GTEx ENSG00000006059 GTEx
  ENSG00000261986 GTEx
  ENSG00000292027 GTEx
HGNC ID HGNC:6450 ENTREZGENE
Human Proteome Map KRT33A Human Proteome Map
InterPro IF_conserved UniProtKB/Swiss-Prot
  IF_rod_dom UniProtKB/Swiss-Prot
  Keratin_I UniProtKB/Swiss-Prot
KEGG Report hsa:3883 UniProtKB/Swiss-Prot
NCBI Gene 3883 ENTREZGENE
OMIM 602761 OMIM
PANTHER KERATIN, TYPE I CUTICULAR HA3-I UniProtKB/Swiss-Prot
  PTHR23239 UniProtKB/Swiss-Prot
Pfam Filament UniProtKB/Swiss-Prot
PharmGKB PA30239 PharmGKB
PRINTS TYPE1KERATIN UniProtKB/Swiss-Prot
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot
  IF_ROD_2 UniProtKB/Swiss-Prot
SMART Filament UniProtKB/Swiss-Prot
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/Swiss-Prot
UniProt B2RA87 ENTREZGENE
  KT33A_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q6NTB9 ENTREZGENE
  Q6ZZB9 ENTREZGENE
UniProt Secondary B2RA87 UniProtKB/Swiss-Prot
  Q6NTB9 UniProtKB/Swiss-Prot
  Q6ZZB9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 KRT33A  keratin 33A    keratin 33A, type I  Symbol and/or name change 5135510 APPROVED
2015-01-27 KRT33A  keratin 33A, type I    keratin 33A  Symbol and/or name change 5135510 APPROVED