Ppic (peptidylprolyl isomerase C)

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Gene: Ppic (peptidylprolyl isomerase C) Mus musculus

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Symbol:

Ppic

Name:

peptidylprolyl isomerase C

RGD ID:

1551298

MGI Page

MGI

Description:

Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human PPIC (peptidylprolyl isomerase C).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cyclophilin C; CyP-20; CyP-20c; peptidyl-prolyl cis-trans isomerase C; PPIase C; rotamase C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPIC (peptidylprolyl isomerase C)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Ppic (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ppic (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPIC (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PPIC (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppic (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPIC (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPIC (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ppic (peptidylprolyl isomerase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Ppic (peptidylprolyl isomerase C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PPIC (peptidylprolyl isomerase C)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CPR5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CPR2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	cyn-5	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Drosophila melanogaster (fruit fly):	ninaA	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	ppic	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	53,539,413 - 53,551,079 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	53,539,404 - 53,551,187 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	53,406,341 - 53,418,007 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	53,406,332 - 53,418,115 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	53,565,995 - 53,577,661 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	53,531,710 - 53,543,376 (-)	NCBI		MGSCv36	mm8
Celera	18	54,714,243 - 54,725,974 (-)	NCBI		Celera
Cytogenetic Map	18	D1	NCBI
cM Map	18	29.03	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Congenital Lower Urinary Tract Obstruction (ISO)

familial adenomatous polyposis 1 (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Stomach Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (EXP)

1,1-dichloroethene (EXP)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (ISO)

acetamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP,ISO)

alpha-Zearalanol (ISO)

Aroclor 1254 (EXP)

arsenite(3-) (EXP)

atrazine (ISO)

belinostat (ISO)

benzo[a]pyrene (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (ISO)

bisphenol F (EXP,ISO)

calcitriol (ISO)

cannabidiol (EXP)

chlorpyrifos (EXP)

ciguatoxin CTX1B (EXP)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

Cuprizon (ISO)

cytarabine (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

flutamide (ISO)

folic acid (EXP)

furan (ISO)

glycidol (ISO)

indole-3-methanol (ISO)

indometacin (ISO)

isobutanol (ISO)

ivermectin (ISO)

lead(0) (ISO)

lipopolysaccharide (EXP)

menadione (ISO)

mercury dibromide (ISO)

methamphetamine (EXP)

oxaliplatin (ISO)

ozone (EXP)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (EXP)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

PhIP (ISO)

pirinixic acid (EXP)

prothioconazole (ISO)

rotenone (EXP,ISO)

SB 431542 (ISO)

sodium arsenate (EXP)

sodium arsenite (ISO)

Soman (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

thioacetamide (ISO)

thiram (ISO)

titanium dioxide (EXP)

topotecan (ISO)

trichostatin A (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein folding (IBA,IEA)

protein peptidyl-prolyl isomerization (ISO)

regulation of transcription by RNA polymerase II (IEA)

Cellular Component

cytoplasm (IBA,IEA)

intracellular membrane-bounded organelle (IBA)

Molecular Function

cyclosporin A binding (IBA,ISO)

peptidyl-prolyl cis-trans isomerase activity (IBA,IDA,ISO)

protein binding (IPI)

RNA polymerase II CTD heptapeptide repeat P3 isomerase activity (IEA)

RNA polymerase II CTD heptapeptide repeat P6 isomerase activity (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased NK cell number (IAGP)

increased transitional stage T1 B cell number (IAGP)

increased transitional stage T2 B cell number (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.	Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1618811	PMID:1652374	PMID:8203464	PMID:8265636	PMID:8341703	PMID:10349636	PMID:10545201	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12477932
PMID:14610273	PMID:15385446	PMID:15489334	PMID:15604097	PMID:16141072	PMID:16141073	PMID:16458478	PMID:16602821	PMID:21267068	PMID:21873635	PMID:32325033	PMID:33864384
PMID:34321999

Genomics

Comparative Map Data

Ppic
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	53,539,413 - 53,551,079 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	53,539,404 - 53,551,187 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	53,406,341 - 53,418,007 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	53,406,332 - 53,418,115 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	53,565,995 - 53,577,661 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	53,531,710 - 53,543,376 (-)	NCBI		MGSCv36	mm8
Celera	18	54,714,243 - 54,725,974 (-)	NCBI		Celera
Cytogenetic Map	18	D1	NCBI
cM Map	18	29.03	NCBI

PPIC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	123,023,250 - 123,036,725 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	123,023,250 - 123,036,725 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	122,358,945 - 122,372,420 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	122,386,977 - 122,400,324 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	122,386,976 - 122,400,324	NCBI
Celera	5	118,313,549 - 118,326,899 (-)	NCBI		Celera
Cytogenetic Map	5	q23.2	NCBI
HuRef	5	117,547,085 - 117,560,441 (-)	NCBI		HuRef
CHM1_1	5	121,791,686 - 121,805,032 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	123,539,800 - 123,553,272 (-)	NCBI		T2T-CHM13v2.0

Ppic
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	49,040,690 - 49,053,296 (-)	NCBI		GRCr8
mRatBN7.2	18	46,842,410 - 46,855,016 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	46,842,409 - 46,855,017 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	48,900,407 - 48,912,990 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	49,604,751 - 49,617,347 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	47,406,327 - 47,418,910 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	48,372,039 - 48,384,645 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	48,372,041 - 48,384,645 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	47,585,434 - 47,598,040 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	48,886,548 - 48,899,154 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	48,924,172 - 48,936,777 (-)	NCBI
Celera	18	45,024,826 - 45,037,432 (-)	NCBI		Celera
Cytogenetic Map	18	q11	NCBI

Ppic
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955521	1,138,779 - 1,143,356 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955521	1,138,779 - 1,143,345 (-)	NCBI	ChiLan1.0	ChiLan1.0

PPIC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	118,310,584 - 118,324,206 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	116,464,247 - 116,477,625 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	118,415,061 - 118,428,438 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	124,195,133 - 124,208,527 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	124,195,133 - 124,208,527 (-)	Ensembl	panpan1.1		panPan2

PPIC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	12,882,676 - 12,893,337 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	12,883,113 - 12,889,427 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	11,664,158 - 11,676,350 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	13,588,849 - 13,601,068 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	13,589,286 - 13,601,063 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	12,328,586 - 12,340,940 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	12,147,497 - 12,159,701 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	12,777,661 - 12,790,143 (-)	NCBI		UU_Cfam_GSD_1.0

Ppic
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	135,327,310 - 135,349,748 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936575	3,408,547 - 3,431,021 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936575	3,408,568 - 3,430,974 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPIC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	126,531,365 - 126,547,753 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	126,531,356 - 126,547,775 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	131,748,541 - 131,764,135 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPIC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	26,079,473 - 26,095,595 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	26,075,893 - 26,095,604 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	52,032,395 - 52,048,741 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppic
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	18,991,646 - 19,002,556 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624774	18,991,651 - 19,002,503 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ppic
441 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	168
Count of miRNA genes:	142
Interacting mature miRNAs:	153
Transcripts:	ENSMUST00000025419
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1302163	Bmd16_m	bone mineral density 16 (mouse)			Not determined		18	29667914	63668060	Mouse
1302099	Hdlq30_m	HDL QTL 30 (mouse)			Not determined		18	51668300	85668468	Mouse
11252137	Modvl5_m	modifier of vacuolated lens 5 (mouse)					18	51052156	85052311	Mouse
11532716	Sluc41c_m	susceptibility to lung cancer 41c (mouse)					18	22619914	56620127	Mouse
11532715	Sluc41b_m	susceptibility to lung cancer 41b (mouse)					18	22619914	56620127	Mouse
10412184	Sstapa1_m	Suseptibility to Staphylococus aureus infection 1 (mouse)			Not determined		18	46541546	57590708	Mouse
11532710	Sluc41a_m	susceptibility to lung cancer 41a (mouse)					18	22619914	56620127	Mouse
25823171	Hrsq10_m	host response to SARS QTL 10, D4% weight (mouse)					18	27241115	58827077	Mouse
11532709	Sluc41_m	susceptibility to lung cancer 41 (mouse)					18	20953694	57590708	Mouse
10412244	Par5_m	pulmonary adenoma resistance 5 (mouse)			Not determined		18	51668300	85668468	Mouse
1301400	Lmr13_m	leishmaniasis resistance 13 (mouse)			Not determined		18	28109380	62109518	Mouse
25823174	Hrsq11_m	host response to SARS QTL 11, log titer (mouse)					18	27241115	58827077	Mouse
1301215	Thcr_m	T helper cell response (mouse)			Not determined		18	45130604	68778777	Mouse
1301853	Heal9_m	wound healing/regeneration 9 (mouse)			Not determined		18	52805276	86805416	Mouse
25823173	Hrsq12_m	host response to SARS QTL 12, hemorrhage (mouse)					18	24895881	78339555	Mouse
1301570	Sluc14_m	susceptibility to lung cancer 14 (mouse)			Not determined		18	22619914	56620127	Mouse
1357639	Obsty4_m	obesity 4 (mouse)			Not determined		18	39619914	84638778	Mouse
4142443	Pgis1_m	proteoglycan induced spondylitis 1 (mouse)			Not determined		18	53291022	76914293	Mouse
1558849	W3q15_m	weight 3 weeks QTL 15 (mouse)			Not determined		18	5041119	61272643	Mouse
12880412	V125Dq12_m	vitamin D active form serum level QTL 12 (mouse)					18	30233067	64233067	Mouse
1301771	Pcyts6_m	plasmacytoma susceptibility 6 (mouse)			Not determined		18	35658632	69658851	Mouse
1301902	Hrtfm4_m	heart failure modifier 4 (mouse)			Not determined		18	43311120	77311343	Mouse
1300877	Adip8_m	adiposity 8 (mouse)			Not determined		18	22619914	56620127	Mouse
4141857	Mhysq5_m	male hybrid sterility QTL 5 (mouse)			Not determined			28130604	62130739	Mouse
1300685	Scc5_m	colon tumor susceptibility 5 (mouse)			Not determined		18	31988480	65988629	Mouse
4142366	Chlq10_m	circulating hormone level QTL 10 (mouse)			Not determined		18	36291022	70291180	Mouse
12050070	Nabq2_m	nasal bone morphology QTL 2 (mouse)					18	39103677	73103793	Mouse
1357630	Tgq1_m	triglyceride QTL 1 (mouse)			Not determined		18	51052156	85052311	Mouse
12904745	Carcdq2_m	cardiac collagen deposition QTL 2 (mouse)					18	46423287	80423287	Mouse
11039493	Ltpr8d_m	Leishmania tropica response 8d (mouse)					18	46874903	80875042	Mouse
1357690	Vtbt19_m	vertebral trabecular bone trait 19 (mouse)			Not determined		18	33091043	67091221	Mouse
11039494	Ltpr8b_m	Leishmania tropica response 8b (mouse)					18	46874903	80875042	Mouse
4142031	Moen1_m	modifier of engrailed QTL 1 (mouse)			Not determined		18	24115560	58115730	Mouse
15039381	Ltgq8_m	liver triglyceride QTL 8 (mouse)					18	38206569	72206569	Mouse
1302050	Radpf4_m	radiation pulmonary fibrosis 4 (mouse)			Not determined		18	52966156	68778777	Mouse
12904950	Smmq3_m	soleus muscle mass QTL 3 (mouse)					18	26056875	60056875	Mouse
15039383	Mvlq5_m	microvesicular liver lesion QTL 5 (mouse)					18	38206569	72206569	Mouse
25823167	Hrsq5_m	host response to SARS QTL 5, D3% weight (mouse)					18	27241115	58827077	Mouse
1357603	Mom3_m	modifier of Min 3 (mouse)			Not determined		18	14030023	67098962	Mouse
13463476	Hctq8_m	hematocrit QTL 8 (mouse)					18	21217580	55217727	Mouse
27226723	Tibw9_m	tibia width 9, proximal, 16 week (mouse)					18	3200000	60933072	Mouse
15039384	Liviq1_m	liver inflammation QTL 1 (mouse)					18	38206569	72206569	Mouse
15039386	Mvlq4_m	macrovesicular liver lesion QTL 4 (mouse)					18	38206569	72206569	Mouse
27226720	Tibw5_m	tibia width 5, proximal, 10 week (mouse)					18	50433067	62633071	Mouse

Markers in Region

UniSTS:224401

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	18	53,406,787 - 53,406,889	UniSTS	GRCm38
MGSCv37	18	53,566,441 - 53,566,543	UniSTS	GRCm37
Celera	18	54,714,689 - 54,714,791	UniSTS
Cytogenetic Map	18	D1	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_008908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC109291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK131931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK150654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK151449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK168911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC025861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M74227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000025419 ⟹ ENSMUSP00000025419

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	18	53,539,404 - 53,551,187 (-)	Ensembl
GRCm38.p6 Ensembl	18	53,406,332 - 53,418,115 (-)	Ensembl

RefSeq Acc Id:

NM_008908 ⟹ NP_032934

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	18	53,539,413 - 53,551,079 (-)	NCBI
GRCm38	18	53,406,341 - 53,418,007 (-)	ENTREZGENE
MGSCv37	18	53,565,995 - 53,577,661 (-)	RGD
Celera	18	54,714,243 - 54,725,974 (-)	RGD
cM Map	18		ENTREZGENE

Sequence:

show sequence

CCGGAGCCTAAGGTTGCGCCCGTGCCATCGTTGCCACTTCCACCGCGCACCATGAGCCCGGGTC
CCCGTCTGCTGCTGCCCGCGGTGCTCTGCCTGGGGCTTGGAGCCCTGGTGTCTTCTTCGGGGTC
CTCAGGCGTCCGAAAACGAGGTCCCTCGGTGACGGACAAGGTCTTCTTTGATGTGAGGATCGGA
GACAAAGATGTGGGTAGAATTGTGATTGGCCTCTTTGGAAACGTTGTACCCAAGACGGTGGAAA
ACTTCGTGGCTCTGGCAACAGGAGAGAAAGGCTACGGGTACAAGGGCAGCATCTTCCACCGTGT
CATCAAGGACTTCATGATTCAAGGAGGGGACTTCACAGCTAGAGATGGCACTGGAGGGATGAGC
ATCTATGGTGAGACATTTCCGGATGAGAACTTCAAACTGAAGCACTATGGCATTGGCTGGGTCA
GCATGGCCAATGCTGGACCAGACACCAACGGATCCCAGTTCTTCATCACCTTGACCAAGCCCAC
CTGGTTGGATGGCAAACACGTTGTATTTGGAAAAGTCCTAGATGGGATGACTGTGGTACATTCC
ATTGAACTTCAAGCAACAGATGGCCATGACCGCCCACTCACCGACTGCACCATCGTCAACAGTG
GCAAGATAGATGTGAAAACACCCTTTGTGGTTGAGGTCCCTGATTGGTGACAGAAATGGCGGAA
GACAGGAAACACACTGGCTGGCCCATGTGCACATCTGTGATCCACCAGCAGTCTTTTAGTTACT
TAAAAGTTGTAGTTAAAAAAATTTCTCATTTAATTTTCCAGTCTCGATTGCAATAACAAAATCA
ACCACACAGTCAGATGTCTCAACAAACACCTGTCATCCCAGTATTTGGGAAGTGCAGGCAGGAG
GATCAGGGGTTCAAGGCCAGCCTGGGCTAACAGTAAGTTTGAGGCTAGCCTTGTCTGTTACATA
AGTAATAACAATAAAAATCAATCAAAGTCCTGCTCAGGAATTTTAAATTGAACGACATATCCTT
CTTTTCTAGTGGTGCTATTTTCAAATCAAAAAACTTTGCATTGGCTATTTGTTTTTACAAACAT
GGTTGAGTTTCACACGGTTCCTTGTGATCTCCATTTGGGTGACCCGAGGGTTTGTTTGAGGAAG
GTGACTATAATGAAGGTTAGCATTTTCTGTTCAAATAGTTCTTGTTCAGGCAAAGGGAAATTTG
AGTAGTATCATATGCTGTATATCATGAGCATTCTGGGGCTTGGATGTTCTTTATATTAAATACT
TTTTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_032934	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA37511	(Get FASTA)	NCBI Sequence Viewer
	AAH25861	(Get FASTA)	NCBI Sequence Viewer
	BAE20880	(Get FASTA)	NCBI Sequence Viewer
	BAE29741	(Get FASTA)	NCBI Sequence Viewer
	BAE30409	(Get FASTA)	NCBI Sequence Viewer
	BAE40724	(Get FASTA)	NCBI Sequence Viewer
	EDL09909	(Get FASTA)	NCBI Sequence Viewer
	EDL09910	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000025419
	ENSMUSP00000025419.8
GenBank Protein	P30412	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_032934 ⟸ NM_008908
- Peptide Label:	precursor
- UniProtKB:	P30412 (UniProtKB/Swiss-Prot), Q3UC73 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSPGPRLLLPAVLCLGLGALVSSSGSSGVRKRGPSVTDKVFFDVRIGDKDVGRIVIGLFGNVVP KTVENFVALATGEKGYGYKGSIFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYG IGWVSMANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVLDGMTVVHSIELQATDGHDRPLTDCT IVNSGKIDVKTPFVVEVPDW hide sequence

Ensembl Acc Id:

ENSMUSP00000025419 ⟸ ENSMUST00000025419

Protein Domains

PPIase cyclophilin-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P30412-F1-model_v2	AlphaFold	P30412	1-212	view protein structure

Promoters

RGD ID:

13677810

Promoter ID:

EPDNEW_M23054

Type:

initiation region

Name:

Ppic_1

Description:

Mus musculus peptidylprolyl isomerase C , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	18	53,418,025 - 53,418,085	EPDNEW

RGD ID:

6829469

Promoter ID:

MM_KWN:25296

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, BoneMarrow_2Hour, ES_Cell, Kidney, Lung, MEF_B4, MEF_B6

Transcripts:

ENSMUST00000025419

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	18	53,577,501 - 53,578,001 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:97751	AgrOrtholog
Ensembl Genes	ENSMUSG00000024538	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000025419	ENTREZGENE
	ENSMUST00000025419.9	UniProtKB/Swiss-Prot
Gene3D-CATH	2.40.100.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Cyclophilin-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cyclophilin-type_PPIase_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cyclophilin-type_PPIase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:19038	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:97751	ENTREZGENE
NCBI Gene	19038	ENTREZGENE
PANTHER	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Pro_isomerase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ppic	PhenoGen
PRINTS	CSAPPISMRASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CSA_PPIASE_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CSA_PPIASE_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50891	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	P30412	ENTREZGENE, UniProtKB/Swiss-Prot
	Q3UC73	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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