PPIC (peptidylprolyl isomerase C)

Gene: PPIC (peptidylprolyl isomerase C) Pan paniscus

Analyze

Symbol:

PPIC

Name:

peptidylprolyl isomerase C

RGD ID:

11996800

Description:

ENCODES a protein that exhibits cyclosporin A binding (inferred); isomerase activity (inferred); peptidyl-prolyl cis-trans isomerase activity (inferred); INVOLVED IN protein folding (inferred); ASSOCIATED WITH Congenital Lower Urinary Tract Obstruction (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred); intracellular membrane-bounded organelle (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

peptidyl-prolyl cis-trans isomerase C

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	118,310,584 - 118,324,206 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	116,464,247 - 116,477,625 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	118,415,061 - 118,428,438 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	124,195,133 - 124,208,527 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	124,195,133 - 124,208,527 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Congenital Lower Urinary Tract Obstruction (ISO)

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Stomach Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein folding (IEA)

Cellular Component

cytosol (IEA)

intracellular membrane-bounded organelle (IEA)

plasma membrane (IEA)

Molecular Function

cyclosporin A binding (IEA)

isomerase activity (IEA)

peptidyl-prolyl cis-trans isomerase activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

PPIC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	118,310,584 - 118,324,206 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	116,464,247 - 116,477,625 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	118,415,061 - 118,428,438 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	124,195,133 - 124,208,527 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	124,195,133 - 124,208,527 (-)	Ensembl	panpan1.1		panPan2

PPIC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	123,023,250 - 123,036,725 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	123,023,250 - 123,036,725 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	122,358,945 - 122,372,420 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	122,386,977 - 122,400,324 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	122,386,976 - 122,400,324	NCBI
Celera	5	118,313,549 - 118,326,899 (-)	NCBI		Celera
Cytogenetic Map	5	q23.2	NCBI
HuRef	5	117,547,085 - 117,560,441 (-)	NCBI		HuRef
CHM1_1	5	121,791,686 - 121,805,032 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	123,539,800 - 123,553,272 (-)	NCBI		T2T-CHM13v2.0

Ppic
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	53,539,413 - 53,551,079 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	53,539,404 - 53,551,187 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	53,406,341 - 53,418,007 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	53,406,332 - 53,418,115 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	53,565,995 - 53,577,661 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	53,531,710 - 53,543,376 (-)	NCBI		MGSCv36	mm8
Celera	18	54,714,243 - 54,725,974 (-)	NCBI		Celera
Cytogenetic Map	18	D1	NCBI
cM Map	18	29.03	NCBI

Ppic
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	49,040,690 - 49,053,296 (-)	NCBI		GRCr8
mRatBN7.2	18	46,842,410 - 46,855,016 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	46,842,409 - 46,855,017 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	48,900,407 - 48,912,990 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	49,604,751 - 49,617,347 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	47,406,327 - 47,418,910 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	48,372,039 - 48,384,645 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	48,372,041 - 48,384,645 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	47,585,434 - 47,598,040 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	48,886,548 - 48,899,154 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	48,924,172 - 48,936,777 (-)	NCBI
Celera	18	45,024,826 - 45,037,432 (-)	NCBI		Celera
Cytogenetic Map	18	q11	NCBI

Ppic
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955521	1,138,779 - 1,143,356 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955521	1,138,779 - 1,143,345 (-)	NCBI	ChiLan1.0	ChiLan1.0

PPIC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	12,882,676 - 12,893,337 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	12,883,113 - 12,889,427 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	11,664,158 - 11,676,350 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	13,588,849 - 13,601,068 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	13,589,286 - 13,601,063 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	12,328,586 - 12,340,940 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	12,147,497 - 12,159,701 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	12,777,661 - 12,790,143 (-)	NCBI		UU_Cfam_GSD_1.0

Ppic
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	135,327,310 - 135,349,748 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936575	3,408,547 - 3,431,021 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936575	3,408,568 - 3,430,974 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPIC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	126,531,365 - 126,547,753 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	126,531,356 - 126,547,775 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	131,748,541 - 131,764,135 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPIC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	26,079,473 - 26,095,595 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	26,075,893 - 26,095,604 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	52,032,395 - 52,048,741 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppic
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	18,991,646 - 19,002,556 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624774	18,991,651 - 19,002,503 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003826694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034960413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000062900 ⟹ ENSPPAP00000039987

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	124,195,133 - 124,208,527 (-)	Ensembl

RefSeq Acc Id:

XM_003826694 ⟹ XP_003826742

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	118,310,584 - 118,324,206 (-)	NCBI
NHGRI_mPanPan1	5	116,464,247 - 116,477,625 (-)	NCBI
Mhudiblu_PPA_v0	5	118,415,061 - 118,428,438 (-)	NCBI
PanPan1.1	5	124,195,133 - 124,208,527 (-)	NCBI

Sequence:

show sequence

ACCGGGAGCGCGCAGGCGCAGCCGGCCGGGAGTCCCGTCAGCTGTCCCAGAGCCTGTGTCGCGC
CCGTGCCGGTAGCGCCCGTGCCGGTAGCGCCGCTGCCACCGCTCACCATGGGCCCGGGTCCTCG
GCTGCTGCTACCTCTCGTGCTTTGCGTGGGGCTCGGCGCACTTGTGTTTTCTTCGGGGGCCGAG
GGCTTCCGCAAGCGAGGCCCCTCGGTGACGGCCAAGGTCTTCTTTGATGTGAGGATTGGAGACA
AAGATGTTGGCAGAATTGTTATTGGCCTCTTTGGAAAAGTTGTGCCCAAGACAGTGGAAAATTT
TGTTGCTCTAGCAACAGGAGAGAAAGGATATGGATATAAAGGAAGCAGGTTTCATCGTGTCATC
AAGGATTTCATGATTCAAGGAGGTGACATCACCGCTGGAGATGGCACTGGGGGTGTGAGCATCT
ATGGTGAGACATTTCCAGATGAGAACTTCAAGCTGAAGCACTATGGCATTGGGTGGGTCAGCAT
GGCCAACGCTGGGCCTGACACCAATGGCTCTCAGTTCTTTATCACCTTGACCAAGCCCACCTGG
TTGGATGGCAAACATGTGGTGTTTGGAAAAGTCATTGATGGGATGACAGTGGTGCACTCCATAG
AGCTCCAAGCAACTGATGGGCATGACCGTCCACTCACCAACTGCTCGATCGTCAACAGTGGCAA
GATAGACGTGAAAACGCCTTTTGTGGTTGAGGTCGCTGATTGGTGACACAACTGGCAGAAAACA
AGGATACGCTTTGGCAGGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTTTG
TGTGTGTGTGTGTGGTGTGTTGTCTTTCAATTATTTGCTTTTTTTTTTTACTTTCTTTTTGTAT
TCTATCCCAGATCACAGGAAAGTTATAAAAATCAAACCGTCACCCTTTAGTTTGCTTGAACTTT
AGTAAACCACCTGCTTAGGGACTTTGAACTTAAATATATCCCCTCCCTCAAGTGGTGCTATTTT
AAAACTAAAAAAAACTTTGAATTGGCTATTTTTTTAATGCAATATTTTTTTTCTGAATTCATTA
TGATCCCCATATTGGGTAATGCTGAACATTTATCTGAAACAGATGAGGATATTAAGTTTATTAT
TTTGTATCCAAACAGAAATTCAGAGAAAGGGAAATTTGACTAGTGTAATCTGAGATATGTCATA
GGGATTTCTTTCTGACAAAAGGGTGCTTTGCTGTTCTTTATATTAAATACTTTTAGATCAAC

hide sequence

Protein Sequences


Protein RefSeqs	XP_003826742	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000039987
	ENSPPAP00000039987.1

RefSeq Acc Id:

XP_003826742 ⟸ XM_003826694

- UniProtKB:

A0A2R9CNV6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGPGPRLLLPLVLCVGLGALVFSSGAEGFRKRGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVP
KTVENFVALATGEKGYGYKGSRFHRVIKDFMIQGGDITAGDGTGGVSIYGETFPDENFKLKHYG
IGWVSMANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVIDGMTVVHSIELQATDGHDRPLTNCS
IVNSGKIDVKTPFVVEVADW

hide sequence

RefSeq Acc Id:

ENSPPAP00000039987 ⟸ ENSPPAT00000062900

Protein Domains

PPIase cyclophilin-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000042661	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000062900.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.100.10	UniProtKB/TrEMBL
InterPro	Cyclophilin-like_dom_sf	UniProtKB/TrEMBL
	Cyclophilin-type_PPIase_CS	UniProtKB/TrEMBL
	Cyclophilin-type_PPIase_dom	UniProtKB/TrEMBL
KEGG Report	pps:100975611	UniProtKB/TrEMBL
NCBI Gene	PPIC	ENTREZGENE
PANTHER	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	UniProtKB/TrEMBL
	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H	UniProtKB/TrEMBL
Pfam	Pro_isomerase	UniProtKB/TrEMBL
PRINTS	CSAPPISMRASE	UniProtKB/TrEMBL
PROSITE	CSA_PPIASE_1	UniProtKB/TrEMBL
	CSA_PPIASE_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50891	UniProtKB/TrEMBL
UniProt	A0A2R9CNV6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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