Or7g27 (olfactory receptor family 7 subfamily G member 27) - Rat Genome Database

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Gene: Or7g27 (olfactory receptor family 7 subfamily G member 27) Mus musculus
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Symbol: Or7g27
Name: olfactory receptor family 7 subfamily G member 27
RGD ID: 1550995
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including OR7G2 (olfactory receptor family 7 subfamily G member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x5J8B7W6RL5-13522154-13521822; GA_x6K02T2PVTD-13076685-13077623; MGC157541; MOR150; MOR150-1; MOR150-1P; MOR150-2; olfactory receptor 1522, pseudogene 1; olfactory receptor 845; olfactory receptor GA_x5J8B7W6RL5-13522154-13521822; olfactory receptor MOR150-1P; olfactory receptor MOR150-2; Olfr1522-ps1; Olfr845
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39919,249,755 - 19,250,696 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl919,247,753 - 19,253,014 (+)EnsemblGRCm39 Ensembl
GRCm38919,338,459 - 19,339,400 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl919,336,457 - 19,341,718 (+)EnsemblGRCm38mm10GRCm38
MGSCv37919,142,903 - 19,143,844 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36919,088,864 - 19,089,802 (+)NCBIMGSCv36mm8
Celera916,617,564 - 16,618,505 (+)NCBICelera
Cytogenetic Map9A2NCBI
cM Map97.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:15081110   PMID:21267068   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or7g27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39919,249,755 - 19,250,696 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl919,247,753 - 19,253,014 (+)EnsemblGRCm39 Ensembl
GRCm38919,338,459 - 19,339,400 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl919,336,457 - 19,341,718 (+)EnsemblGRCm38mm10GRCm38
MGSCv37919,142,903 - 19,143,844 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36919,088,864 - 19,089,802 (+)NCBIMGSCv36mm8
Celera916,617,564 - 16,618,505 (+)NCBICelera
Cytogenetic Map9A2NCBI
cM Map97.27NCBI
OR7G2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,100,407 - 9,107,475 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl199,100,407 - 9,107,475 (-)EnsemblGRCh38hg38GRCh38
GRCh37199,211,083 - 9,218,151 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,073,945 - 9,074,982 (-)NCBINCBI36Build 36hg18NCBI36
Build 34199,073,944 - 9,074,982NCBI
Celera199,108,385 - 9,109,422 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef198,794,541 - 8,795,578 (-)NCBIHuRef
CHM1_1199,212,647 - 9,213,684 (-)NCBICHM1_1
T2T-CHM13v2.0199,226,573 - 9,233,642 (-)NCBIT2T-CHM13v2.0
Or7g31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8825,332,469 - 25,333,407 (-)NCBIGRCr8
mRatBN7.2817,056,179 - 17,057,117 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl817,053,661 - 17,057,239 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx821,062,683 - 21,063,621 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0819,360,512 - 19,361,450 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0817,276,438 - 17,277,376 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0819,332,109 - 19,333,047 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl819,332,109 - 19,333,047 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0819,400,511 - 19,401,449 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4817,484,318 - 17,485,256 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1817,484,317 - 17,485,256 (-)NCBI
Celera818,471,387 - 18,472,325 (-)NCBICelera
Cytogenetic Map8q13NCBI
OR7G13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12051,634,215 - 51,635,174 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2051,497,790 - 51,498,728 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02052,156,210 - 52,157,148 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2052,156,210 - 52,157,148 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12051,362,921 - 51,363,859 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,788,667 - 51,789,605 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02052,030,336 - 52,031,274 (-)NCBIUU_Cfam_GSD_1.0
LOC110259632
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1267,202,992 - 67,203,963 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in Or7g27
40 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSMUST00000071259
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
35673312Ari7_mantibody response to influenza 7, day 45, IgG3 (mouse)9780000122211296Mouse
1300849Sles4_msystemic lupus erythmatosus suppressor 4 (mouse)Not determined9910756237306370Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130341840Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902913Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse

Markers in Region
UniSTS:491967  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38919,338,429 - 19,339,471UniSTSGRCm38
MGSCv37919,142,873 - 19,143,915UniSTSGRCm37
Celera916,617,534 - 16,618,576UniSTS
Cytogenetic Map9A2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000071259   ⟹   ENSMUSP00000071239
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl919,249,755 - 19,250,696 (+)Ensembl
GRCm38.p6 Ensembl919,338,459 - 19,339,400 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213344   ⟹   ENSMUSP00000149986
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl919,247,795 - 19,253,014 (+)Ensembl
GRCm38.p6 Ensembl919,336,499 - 19,341,718 (+)Ensembl
Ensembl Acc Id: ENSMUST00000215572   ⟹   ENSMUSP00000150474
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl919,247,753 - 19,253,014 (+)Ensembl
GRCm38.p6 Ensembl919,336,457 - 19,341,718 (+)Ensembl
RefSeq Acc Id: NM_207145   ⟹   NP_997028
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39919,249,755 - 19,250,696 (+)NCBI
GRCm38919,338,459 - 19,339,400 (+)ENTREZGENE
MGSCv37919,142,903 - 19,143,844 (+)RGD
Celera916,617,564 - 16,618,505 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_997028 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI27983 (Get FASTA)   NCBI Sequence Viewer  
  AAL61505 (Get FASTA)   NCBI Sequence Viewer  
  AAM26990 (Get FASTA)   NCBI Sequence Viewer  
  AAP71326 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000071239
  ENSMUSP00000071239.3
  ENSMUSP00000149986.2
  ENSMUSP00000150474.2
RefSeq Acc Id: NP_997028   ⟸   NM_207145
- UniProtKB: Q7TRG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000071239   ⟸   ENSMUST00000071259
Ensembl Acc Id: ENSMUSP00000149986   ⟸   ENSMUST00000213344
Ensembl Acc Id: ENSMUSP00000150474   ⟸   ENSMUST00000215572
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TRG2-F1-model_v2 AlphaFold Q7TRG2 1-312 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030679 AgrOrtholog
Ensembl Genes ENSMUSG00000061614 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000071259 ENTREZGENE
  ENSMUST00000071259.3 UniProtKB/TrEMBL
  ENSMUST00000213344.2 UniProtKB/TrEMBL
  ENSMUST00000215572.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258249 UniProtKB/TrEMBL
MGD MGI:3030679 ENTREZGENE
NCBI Gene 258249 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 7G2 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or7g27 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TRG2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or7g27  olfactory receptor family 7 subfamily G member 27  Olfr845  olfactory receptor 845  Symbol and/or name change 5135510 APPROVED
2016-02-23 Olfr845  olfactory receptor 845  Olfr1522-ps1  olfactory receptor 1522, pseudogene 1  Data merged from RGD:1618034 737654 PROVISIONAL